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Journal Reading
PEMBIMBING: DR. ARIF TRI PRASETYO, MKED.KLIN, SPBP-RE
OLEH CAROLINE DEWI
Introduction
 In the 1970s, Behan and Wilson1 coined the concept of angiotome, which
refers to the 3-dimensional tissue unit supplied by a dynamic vascular
network  development of keystone flap
 The KF procedure was first described in 2003
 Highlight the KF’s versatility, reliability, and efficiency in multiple
reconstructive scenarios and raise questions about its successful perfusion.
 The clinical evidence that claims the efficiency of this reconstructive
strategy is overwhelming.
 However, KF is barely addressed in specialized literature and is still far from
becoming a firstline tool in clinical practice. This study reports our
experience using KF and proposes the concept of pedicular area.
Material and methods
 A prospective study was developed from October 2014 to December 2016
(26 months) at Fundación Hospital de la Misericordia and during the main
author’s private practice
 Doppler marking in search of perforators was not performed in any of the
cases.
 The average follow-up time was 10 months, and in all cases, preoperative
and postoperative photographic records were taken.
Result
Surgical Technique
In this series, the trapezoidal design was always the
first step.
Based on this, the axes and edges were adapted to
the donor area, maintaining, as much as possible, the
major axis of the flap parallel to the defect and, at
least in 1 end, the V-Y closure design to optimize the
advance
The major axis of the flap parallel to the cutaneous
nerves and/or known perforators to include them or
over the so-called hot spots.  However, it was
unnecessary in this series.
Proposed an increase in the flap area in relation to the
defect size to “recruit more perforators,” obtaining
defect-size ratios of up to 5:1  In this series, larger
flaps are ideal not for vascular safety but to replace the
entire aesthetic subunits and make the scar less
conspicuous.
Besides, this could prevent the transgression of natural
folds or the location of scars in the area of excessive
pressure (Figs. 2 and 4).
Major advances cannot be made without
circumferential incision of the flaps up to the fascia.
This never caused persistent venous congestion or
arterial damage that compromised flap viability;
therefore, repair of a sacrificed vein was never
considered
no partial or total flap losses, significant incidence
of lymphedema, or healing problems.
does not require identification and skeletonization of source vessel or
specific perforator.  eliminates the risks, complexity, morbidity, and
surgical time implied in these procedures.
NERVE
Preservation of cutaneous nerves is recommended to
exploit neurocutaneous circulation and to preserve KF
sensitivity.
 many of this series flaps exhibited sensitivity in the
postoperative period despite the sectioning of the
superficial nerves and small anchorage areas. (reason
unknown)
VASCULAR
surgical concern  the area that remains attached to
the bed guarantees perfusion
the greater the anchoring area, the smaller the flap
advance potential
Larger flaps dissected up to two-third of the island
in the subfascial plane  good
Dissection starts from the periphery and progresses as
needed, narrowing the flap attaching area to its bed,
which has been called pedicular area (PA).
In this area, no specific vessel or perforator was
isolated or previously identified, but it clearly fulfilled
the flap vascular requirements.
This area contains ubiquitous perforators or
microperforators with the same flow enhancement
observed in isolated perforators of classical flaps.
The PA could be reduced to near 10%; in other words,
up to 90% of the flap was dissected without harm, far
exceeding the ranges recommended by Behan himself
 dissections >90% (PA < 10%)
were successfully performed on
the face, back, thorax, arms,
hands, and legs.
 Whenever possible, the PA
should be located on the so-
called hot spots.
 KFs with narrow PAs presented a
different behavior. Initially, they
showed a period of variable
duration with evident venous
congestion followed by a
vasoconstriction or “white
phase,” which was always sorted
without compromising the KF
vitality (Fig. 3).
The progress achieved with these flaps is proportional to the depth of the
tissues affected and the amount of tissue lifted from its bed.
Therefore, the advance can be sequentially increased via 3 ways:
 1. To design (if possible) flaps larger than the defect, especially if the tissue
has been irradiated or presents burns sequelae, as fibrosis secondary to
these injuries can hinder tissue mobility.
 2. To intervene the underlying fascia on the entire perimeter of the flap.
 3. To dissect the KF in a subfascial plane from the flap periphery to the
chosen pedicular area, which progressively narrows from a wide central
area to a smaller one, distal to the edge of the defect
 4. To choose a not necessarily central pedicular area when designing the
omega variant. The sum of the central zone axial advance and that
achieved by the rotation and advance of the lateral segments allows
covering more extensive and distant defects (Fig. 3).
Discussion
Advantages
 Like with like tissure  aesthetic results
 Short surgical times without complex intrasurgical or postsurgical monitoring
 a single operative field
 a more “stable” perfusion
 reduce morbidity, mortality, and intrahospital stay.
 KF’s versatility, functional and aesthetic results, and low complication rate (3%–
4.6%) have far exceeded the expectations of any random perforator or flap.
 relatively easy and fast technique for the beginner and the experienced
surgeon.
 KF allowed coverage that would require free
flaps or classic perforator flaps
 KF  great alternative for the complete
reconstruction of entire facial subunits, the
recruitment of muscle components
(orbicularis oris, orbicularis oculi, and
platysma), and the successful mobilization of
innervated tissues.
 Compared with skin grafts: more efficient ,
no skin graft undesirable effects such as
retraction, pigmentation
 Narrowing the PA provides wider movement
arcs and, contrary to some opinions, allows
advances over 20cm, and rotations of up to
180 degree.
 These are similar to the helical flap results,
without the technical difficulties, poor
cosmetic results, and morbidity that it entails
Limitation
 Efficiency in intraoral and intranasal coverage has not been sufficiently
proven. Its fasciocutaneous and musculocutaneous nature lacking bone
components
 vascular dependence on perforators, caution should be exercised in areas
surgically or traumatically dissected
 May cause transgression of natural folds or scar location on areas of
excessive pressure.  so use larger flap
Conclusion
KF able to satisfy these reconstructive strategy:
 (1) provides similar tissues in terms of function, texture, color, and
sensitivity;
 (2) is versatile for any reconstructive requirement;
 (3) provokes minimal or no aesthetic or functional morbidity of donor
areas;
 (4) entails short surgical times; and
 (5) is replicable, with short learning curves and without large infrastructure
requirements
Conclusion
 Heterogeneity of the age groups, comorbidities, and anatomical areas
considered adverse to flap perfusion  new cohorts with a larger number of
patients and more strict inclusion criteria are necessary to validate our
conclusions.
 Break fixed anatomically identifiable pedicles paradigm  into “freestyle
pedicles” or “random pedicular area,” free of the complex and expensive
technical requirements of the perforator or free flaps.
Thank You

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Journal Reading- keystone flap.pptx

  • 1. Journal Reading PEMBIMBING: DR. ARIF TRI PRASETYO, MKED.KLIN, SPBP-RE OLEH CAROLINE DEWI
  • 2.
  • 3. Introduction  In the 1970s, Behan and Wilson1 coined the concept of angiotome, which refers to the 3-dimensional tissue unit supplied by a dynamic vascular network  development of keystone flap  The KF procedure was first described in 2003  Highlight the KF’s versatility, reliability, and efficiency in multiple reconstructive scenarios and raise questions about its successful perfusion.  The clinical evidence that claims the efficiency of this reconstructive strategy is overwhelming.  However, KF is barely addressed in specialized literature and is still far from becoming a firstline tool in clinical practice. This study reports our experience using KF and proposes the concept of pedicular area.
  • 4. Material and methods  A prospective study was developed from October 2014 to December 2016 (26 months) at Fundación Hospital de la Misericordia and during the main author’s private practice  Doppler marking in search of perforators was not performed in any of the cases.  The average follow-up time was 10 months, and in all cases, preoperative and postoperative photographic records were taken.
  • 6.
  • 7. Surgical Technique In this series, the trapezoidal design was always the first step. Based on this, the axes and edges were adapted to the donor area, maintaining, as much as possible, the major axis of the flap parallel to the defect and, at least in 1 end, the V-Y closure design to optimize the advance The major axis of the flap parallel to the cutaneous nerves and/or known perforators to include them or over the so-called hot spots.  However, it was unnecessary in this series.
  • 8. Proposed an increase in the flap area in relation to the defect size to “recruit more perforators,” obtaining defect-size ratios of up to 5:1  In this series, larger flaps are ideal not for vascular safety but to replace the entire aesthetic subunits and make the scar less conspicuous. Besides, this could prevent the transgression of natural folds or the location of scars in the area of excessive pressure (Figs. 2 and 4). Major advances cannot be made without circumferential incision of the flaps up to the fascia. This never caused persistent venous congestion or arterial damage that compromised flap viability; therefore, repair of a sacrificed vein was never considered no partial or total flap losses, significant incidence of lymphedema, or healing problems. does not require identification and skeletonization of source vessel or specific perforator.  eliminates the risks, complexity, morbidity, and surgical time implied in these procedures.
  • 9. NERVE Preservation of cutaneous nerves is recommended to exploit neurocutaneous circulation and to preserve KF sensitivity.  many of this series flaps exhibited sensitivity in the postoperative period despite the sectioning of the superficial nerves and small anchorage areas. (reason unknown) VASCULAR surgical concern  the area that remains attached to the bed guarantees perfusion the greater the anchoring area, the smaller the flap advance potential Larger flaps dissected up to two-third of the island in the subfascial plane  good Dissection starts from the periphery and progresses as needed, narrowing the flap attaching area to its bed, which has been called pedicular area (PA). In this area, no specific vessel or perforator was isolated or previously identified, but it clearly fulfilled the flap vascular requirements. This area contains ubiquitous perforators or microperforators with the same flow enhancement observed in isolated perforators of classical flaps. The PA could be reduced to near 10%; in other words, up to 90% of the flap was dissected without harm, far exceeding the ranges recommended by Behan himself
  • 10.  dissections >90% (PA < 10%) were successfully performed on the face, back, thorax, arms, hands, and legs.  Whenever possible, the PA should be located on the so- called hot spots.  KFs with narrow PAs presented a different behavior. Initially, they showed a period of variable duration with evident venous congestion followed by a vasoconstriction or “white phase,” which was always sorted without compromising the KF vitality (Fig. 3).
  • 11. The progress achieved with these flaps is proportional to the depth of the tissues affected and the amount of tissue lifted from its bed. Therefore, the advance can be sequentially increased via 3 ways:  1. To design (if possible) flaps larger than the defect, especially if the tissue has been irradiated or presents burns sequelae, as fibrosis secondary to these injuries can hinder tissue mobility.  2. To intervene the underlying fascia on the entire perimeter of the flap.  3. To dissect the KF in a subfascial plane from the flap periphery to the chosen pedicular area, which progressively narrows from a wide central area to a smaller one, distal to the edge of the defect  4. To choose a not necessarily central pedicular area when designing the omega variant. The sum of the central zone axial advance and that achieved by the rotation and advance of the lateral segments allows covering more extensive and distant defects (Fig. 3).
  • 12.
  • 13. Discussion Advantages  Like with like tissure  aesthetic results  Short surgical times without complex intrasurgical or postsurgical monitoring  a single operative field  a more “stable” perfusion  reduce morbidity, mortality, and intrahospital stay.  KF’s versatility, functional and aesthetic results, and low complication rate (3%– 4.6%) have far exceeded the expectations of any random perforator or flap.  relatively easy and fast technique for the beginner and the experienced surgeon.
  • 14.  KF allowed coverage that would require free flaps or classic perforator flaps  KF  great alternative for the complete reconstruction of entire facial subunits, the recruitment of muscle components (orbicularis oris, orbicularis oculi, and platysma), and the successful mobilization of innervated tissues.  Compared with skin grafts: more efficient , no skin graft undesirable effects such as retraction, pigmentation  Narrowing the PA provides wider movement arcs and, contrary to some opinions, allows advances over 20cm, and rotations of up to 180 degree.  These are similar to the helical flap results, without the technical difficulties, poor cosmetic results, and morbidity that it entails
  • 15. Limitation  Efficiency in intraoral and intranasal coverage has not been sufficiently proven. Its fasciocutaneous and musculocutaneous nature lacking bone components  vascular dependence on perforators, caution should be exercised in areas surgically or traumatically dissected  May cause transgression of natural folds or scar location on areas of excessive pressure.  so use larger flap
  • 16. Conclusion KF able to satisfy these reconstructive strategy:  (1) provides similar tissues in terms of function, texture, color, and sensitivity;  (2) is versatile for any reconstructive requirement;  (3) provokes minimal or no aesthetic or functional morbidity of donor areas;  (4) entails short surgical times; and  (5) is replicable, with short learning curves and without large infrastructure requirements
  • 17. Conclusion  Heterogeneity of the age groups, comorbidities, and anatomical areas considered adverse to flap perfusion  new cohorts with a larger number of patients and more strict inclusion criteria are necessary to validate our conclusions.  Break fixed anatomically identifiable pedicles paradigm  into “freestyle pedicles” or “random pedicular area,” free of the complex and expensive technical requirements of the perforator or free flaps.