Hydropic degeneration is a type of cellular injury characterized by the accumulation of fluid within cells, causing them to swell. This fluid accumulation can displace or compress organelles and impair cellular function, ultimately leading to cell death if left unresolved. Causes of hydropic degeneration include ischemic injury from reduced blood flow, certain infections, toxins, metabolic disorders, and genetic disorders. Microscopically, hydropic degeneration is evident by cellular swelling, vacuolation within the cytoplasm, distorted cell shape, nuclear pyknosis, and loss of cellular function.

1. Hydropic degeneration
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2. Introduction
• Hydropic degeneration, also known as cellular
swelling or vacuolar degeneration, is a type of cellular
injury characterized by the accumulation of fluid
within cell

3. Cont...
•The accumulation of fluid within the cell can
cause the cell to swell and can lead to the
formation of vacuoles within the cytoplasm.
This can displace or compress cellular
organelles, impair cellular metabolism, and
ultimately result in cell death if the
underlying cause is not resolved.

4. Cusses of Hydropic degeneration
•1. Ischemic injury: A lack of oxygen and
nutrients due to reduced blood flow can
cause cells to become swollen and Hydropic.
2. Infections: Certain viral, bacterial, or
fungal infections can cause cellular swelling
and Hydropic degeneration.

5. Cont..
3. Toxins: Exposure to toxins such as drugs,
chemicals, or poisons can damage cells and
cause Hydropic degeneration.
4. Metabolic disorders: Certain metabolic
disorders, such as liver or kidney disease, can
cause fluid accumulation within cells and lead
to Hydropic degeneration.

6. Cont..
•5. Genetic disorders: Certain
genetic disorders can cause
abnormal cellular metabolism and
lead to Hydropic degeneration.

7. Microscopic futures of Hydropic degeneration
•1. Cellular swelling: Cells appear larger than
normal due to the accumulation of fluid
within the cytoplasm.
•2. Vacuolation: The cytoplasm of affected
cells may contain numerous clear vacuoles,
which may displace or compress cellular
organelles

8. Cont..
•3. Distorted cellular shape: Cells may lose
their normal shape due to the accumulation
of fluid and Vacuolation.
4. Pyknosis: The nucleus of affected cells
may become shrunken and condensed.

9. Cont...
•5. Loss of cellular function: The
accumulation of fluid and
Vacuolation can interfere with
cellular metabolism and lead to
impaired cellular function.

10. •Thanks