Body Composition, Exercise Physiology, & Metabolism Core at the University of California, San Francisco
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Body Composition, Exercise Physiology, & Metabolism Core at the University of California, San Francisco
- 1. Clinical & Translational BODY COMPOSITION, EXERCISE PHYSIOLOGY, Sciences Institute AND METABOLISM CORE Kathleen Mulligan, PhD, Core Director UCSF OVERVIEW SERVICES • Testing performed by specialists under appropriate medical supervision at Moffitt and SFGH Clinical • Dual-energy X-ray Research Centers, serving all CTSI investigators absorptiometry (DXA) for • State-of-the art equipment and methodologies body composition and bone • All services offered on a cost-recovery basis for both investigator-initiated and industry-sponsored density testing in adults, studies in adult and pediatric populations children, infants • Testing available at other CTSI locations by special arrangement • Bioimpedance analysis: • In past year, our core supported 40 CTSI protocols (35 adult, 5 pediatric) by 36 principal investigators, single and multi-frequency including 10 fellows/junior faculty • BodPod© air displacement plethysmography (Moffitt) • Anthropometry EXAMPLES OF ASSESSMENTS • Treadmill testing • Cycle ergometry OUR TEAM • Exercise testing with full EKG monitoring • Peak or max VO2 Infant DXA Spine Hip Forearm DXA for bone density • Resting energy expenditure (body composition) by indirect calorimetry Dual energy x-ray Whole-body DXA absorptiometry (DXA) (body composition) • 6-minute walk test, gait John Duda, RN speed, stair climb, grip Moffitt Lab Manager strength • Spirometry (Moffitt) • Activity monitoring • Ultrasound equipment Anthropometry Indirect calorimetry VO2 max available (Moffitt) during glucose clamp BodPod • Other testing as required • Consulting A FEW EXAMPLES OF RECENT STUDIES Viva Tai, RD, MPH • Training study personnel in DXA specialist (SFGH) • Body composition and exercise capacity in rheumatoid arthritis and lupus simple procedures • Metabolic impact of fructose restriction in obese children • Effects of tenofovir and other antiretrovirals on bone density (HIV+ and HIV-negative) • Assistance with grant • Home-based exercise program in children with cystic fibrosis preparation, data • Frailty and functional capacity in patients undergoing lung transplant interpretation • Paleolithic diet in type 2 diabetes mellitus • Visceral adiposity, HIV, and HCV: biologic mediators of hepatic steatosis • Referrals to UCSF groups for • Bone density in hepatitis other services (e.g. heavy For further information, please contact: • Metabolic effects of sleep deprivation Kathleen Mulligan, PhD • Levofloxacin in cystic fibrosis water analysis, imaging) kathleen.mulligan@ucsf.edu • Effects of HIV and menopause on musculoskeletal health • Novel interventions to reduce stress induced non-homeostatic eating • Effects of gastric bypass surgery on calcium metabolism in the spine