NEW WHO CLASSIFICATION

1. CNS TUMORS- WHO
Classification 2016
DR ANAMIKA DEV

2. 1. Diffuse astrocytic & oligodendroglial tumours
2. Other astrocytic tumours
3. Ependymal tumours
4. Other gliomas
5. Choroid plexus tumours
6. Neuronal & Mixed neuronal-glial tumours
7. Tumours of pineal region
8. Embryonal tumours
9. Tumours of Cranial & Paraspinal nerves
10. Meningiomas
11. Mesenchymal, non-meningothelial tumours
12. Melanocytic tumours
13. Lymphomas
14. Histiocyic tumours
15. GCT
16. Tumours of sellar regions
17. Metastatic tumours

3. 1.DIFFUSE ASTROCYTIC & OLIGODENDROGLIAL
TUMOURS: (No WHO grade I infiltrating astrocytoma)

4. 2.OTHER ASTROCYTIC TUMOURS:
More circumscribed growth pattern,
Lack IDH gene family alterations
Frequently have BRAF alterations/ TSC1/TSC2 mutations

5. 3.Ependymal tumors

6. 4.Other gliomas

7. 5. Choroid plexus tumors
• Choroid plexus papilloma
• Atypical Choroid plexus papilloma
• Choroid plexus carcinoma

8. Meningiomas
• WHO Grade 1
– Meningothelial meningioma
– Fibroblastic
– Transitional
– Psamommatous
– Secretory
– Microcystic
– Angiomatous
– Lymphoplasmacyte- rich
– metaplastic
• WHO Grade 2
– Clear cell
– Chordoid
– atypical
• WHO Grade 3
– Rhabdoid
– Papillary
– Anaplastc