1. Alexander Schlachterman
alexschlach@gmail.com
215 450 9390
Post Graduate Training
7/2013-Present Gastroenterology Fellowship
University of Florida, UF Health, Gainesville, Florida
7/2010-6/2013 Internal Medicine Residency/Internship
Hahnemann University Hospital / Drexel University College of Medicine, Philadelphia,
Pennsylvania.
7/2009-6/2010 General Surgery-Preliminary Internship
Hahnemann University Hospital / Drexel University College of Medicine, Philadelphia,
Pennsylvania.
Education
8/2005-6/2009 Universidad Central del Caribe Medical School, Bayamon, Puerto Rico
M.D., 6/2009
9/2003-6/2004 University of the Sciences in Philadelphia, Philadelphia, Pennsylvania
Graduate course work: Cell Biology and Biotechnology
9/1996-06/1999 University of Pennsylvania, Philadelphia, Pennsylvania
Bachelor of Arts: Biology/Immunology
Certification
BLS Basic Life Support
ACLS Advanced Cardiac Life Support
ATLS Advanced Trauma Life Support
Employment
2004-present Research Consultant, Independent consultant to principal investigators of medical
research, specializing in murine models. Clients & Collaborators:
• Children’s Hospital of Phila • Howard Hughes Medical Inst, Phila
• University of Penn, Phila. • University of Alabama, Birmingham
• U. of Florida, Gainesville • Univesidad Central del Caribe, PR
• Wistar Institue, Phila. • Fox Chase Cancer Center, Phila.
• Intrexon Corp, VA.
2003-2005 Senior Research Associate, Katherine High, MD, Children’s Hospital of
Philadelphia/Howard Hughes Medical Institute, Department of Hematology,
Philadelphia, PA. Investigate gene therapy treatments for hemophilia.
2002-2003 Scientist, David Sutton, GlaxoSmithKline, Dept. of Molecular and Cellular Oncology,
Collegeville, PA. Investigated in-vivo drug efficacy on tumor growth.
2000-2002 Research Specialist, Amit Maity, MD, PhD, University of Pennsylvania School of
Medicine, Dept. of Radiation Oncology, Philadelphia, PA. Studied the effects of
hyperbaric medicine on tumor growth and gene expression due to hypoxia.
1998-2000 Research Technician, Ali Naji, MD, PhD, University of Pennsylvania School of
Medicine, Harrison Dept. of Surgical Research, Philadelphia, PA. Investigated the
pathogenesis of autoimmune diabetes and transplant rejection.
1998-1999 Senior Thesis, Ali Naji, MD, PhD, University of Pennsylvania School of Medicine,
Philadelphia, PA. “Anergic T Cells: Active Suppressors or Idle Bystanders?” and
“Investigation of the Nature of Peripheral Immune Tolerance to Self.”

2. Alexander Schlachterman
alexschlach@gmail.com
215 450 9390
Publications / Book Chapter:
Sherman A, Schlachterman A, Cooper M, Merricks EP, Raymer RA, Bellinger DA, Herzog RW, Nichols
TC. Portal vein delivery of viral vectors for gene therapy for hemophilia. Methods Mol Biol.
2014;1114:413-26. Book Chapter. PMID: 24557919
Comparison of Internal Medicine Residents to GI Fellows in the Assessment of Patients with GI bleeding
at an Inner-City University Teaching Hospital: Are Patients Triaged Appropriately? Priti Bijpuria,
Schlachterman, A. and Ahmad, A., In press; Hospital Medicine.
Solomon, M., Schlachterman, A., Morgenstern, R. Iatrogenic duodenal perforation
treated with endoscopic placement of metallic clips, A Case Report. Case Reports in Medicine,
2012; 2012:609750. Epub 2012 Feb 12.PMCID: PMC3297480.
Schlachterman, A., Ahmad, A.. Gastrointestinal Morbidity following Crack-Cocaine Use: Clinical
Observation., Practical Gastroenterology, Fellows’ Corner, December 2011. 35(12)54-55.
Ivanciu, L., Toso, R., Schlachterman, A., Liu, J., Arruda,V. R. and Camire, R. M.. A zymogen-like factor
Xa variant corrects the coagulation defect in hemophilia. Nature Biotechnology. 2011 Oct 23;29(11):1028-
33. PMID:22020385.
Li H., Malani N., Hamilton S.R., Schlachterman, A., Bussadori G., Edmonson S.E., Shah R., Arruda V.R.,
Mingozzi F., Wright J.F., Bushman F.D., High K.A.. Assessing the potential for AAV vector genotoxicity in
a murine model. Blood. 2011 Jun 16;117(24):6739. PMID:21106988.
Gupta, S., Kühnich, J., Mustafa, A., Lhotak, S., Schlachterman, A., Slifker, M. J., Klein-Szanto, A., High,
K.A., Austin, R.C. and Kruger, W.D.. Mouse Models of Cystathionine β-Synthase Deficiency Reveal
Significant Threshold Effects of Hyperhomocysteinemia. FASEB J. 2009 Mar;23(3):883-93.
PMID:18987302
Aljamali, M.N., Margaritis, P., Schlachterman, A., Tai, S.J., Roy, E., Bunte, R., Camire, R.M., High,
K.A.. Long-term expression of murine activated factor VII is safe, but elevated levels cause premature
mortality. J Clin Invest. 2008 May;118(5):1825-34. PMID:18398505.
Schlachterman, A., Valle F., Morell, L., Azios, N.G., Cubano, L.A. and Dharmawardhane, S.. Red wine
polyphenols reduce breast tumor growth in a nude mouse model. Translational Oncology, 1(1)19-27.
March 2008. PMID:18607509
Murphy, S.L., Li, H., Zhou, S., Schlachterman, A., High, K.A.. Prolonged Susceptibility to Antibody-
mediated Neutralization for Adeno-associated Vectors Targeted to the Liver. Molecular Therapy. 2008
Jan;16(1):138-45. PMID:17955024.
Cao, O., Armstrong, E., Schlachterman, A., Wang, L., Okita, D.K., Conti-Fine, B., High, K.A., Herzog,
R.W.. Immune Deviation by Mucosal Antigen Administration Suppresses Gene Transfer-Induced Inhibitor
formation to FIX. Blood. 2006 Jul 15;108(2):480-6. PMID:16543469.
Schlachterman, A., Liu, J., Fergusi, C., Schuettrumpf, J. and Arruda, V.R.. In Vivo Evidence of
Modulation of the Hemophilia Phenotype by the Factor V Leiden. Journal of Thrombosis and
Haemostasis. 3:2730-2737, December 2005. PMID:16359510.
Schuettrumpf, J., Zou, J., Zhang, Y., Schlachteman, A., Lui, Y., Edmonson, S., Xiao, W. and Arruda,V.R..
The Inhibitory Effects of Anticoagulation on In Vivo Gene Transfer by Adeno-associated Viral or
Adenoviral Vectors. Molecular Therapy, 3(1) 88-97. Oct. 2005.
PMID:16230049.
Wang, L., Dobrzynski, E., Schlachterman, A., Cao, O., Herzog, R.W.. Systemic protein delivery by
muscle-gene transfer is limited by a local immune response. Blood. 1;105(11):4226-34. June 2005.
PMID:15713796.

3. Alexander Schlachterman
alexschlach@gmail.com
215 450 9390
Zhang, H., High, K.A., Wu, Q., Yang, P., Schlachterman, A., Yu, S., Yi, N., Hsu, H. and Mountz, J.D..
Genetic Analysis of the Antibody Response to AAV2 and Factor IX. Molecular Therapy. 11(6):866-74, June
2005. PMID:15922957.
Schuettrumpf, J., Herzog, R.W., Schlachteman, A., Kaufhold, A., .Stafford, D.W. and Arruda, V.R..
Factor IX Variants Improve GeneTherapy Efficacy for Hemophilia. Blood, 105(6):2316-23, March 2005.
PMID:15550487.
Margariti, P., Arruda, V.R., Aljamali, M., Camire, R.M., Schlachterman, A. and High, K.A.. Novel
Therapeutic Approach for Hemophilia Using Gene Delivery of an Engineered Secreted Activated Factor
VII. Journal of Clinical Investigation.113(7):1025-31, April 2004. PMID:15057309
Greeley, S.A., Moore, D.J., Noorchashm, H., Noto, L., Schlachterman, A., Rostami, S., Koeberlein, B.
Barker, C.F. and Naji, A.. Impaired Activation of Islet-Reactive CD4 T Cells in Pancreatic Lymph Nodes of
B Cell-Deficient Nonobeses Diabetic Mice. Journal of Immunology. 167(8):4351-7, October. 15, 2001.
PMID:11591759.
Schlachterman, A., Noorchashm, H., Barker, C.F. and Naji, A.. Maintenance of Peripheral Tolerance to
Allografts is Mediated Via Immunological Ignorance: A Correlation with Resistance to AICD. American
Journal of Transplantation, ASTA supplement 2000.
Noorchashm, H., Moore, D.J., Lieu, Y.K., Noorchashm, N., Schlachterman, A., Song, H.K., Barker C.F.,
and Naji, A.. Contribution of the Innate Immune System to Autoimmune Diabetes: A Role for the CR1/CR2
Complement Receptors. Cellular Immunology. 195(1):75-9, July 10, 1999. PMID:10433799.
Noorchashm, H., Lieu, Y., Noorchashm, N., Rostami, S., Greeley, S.A., Schlachterman, A., Song, H.K.,
Noto, L., Jevnikar, A., Barker, C.F. and Naji, A.. I-Ag7-Mediated Antigen Presentation by B Lymphocytes
I Critical in Overcoming a Checkpoint in T Cell Tolerance to Islet Cells of Nonobese Diabetic Mice.
Journal of Immunology. 162(5):2467-71, July 1999. PMID:10395666.
Current Projects:
Pancreatic Function Tests; What is the best approach? Schlachterman, A. Gupte, A, and Forsmark, C.
Alimentary Pharmacology & Therapeutics. Invited Review 2015.
Cystic neoplasm and IPMN. Schlachterman, A, Gupte, A., Brugge, W. and Forsmark, C.. Lippincott
Book Chapter.
Impact of preoperative endoscopic ultrasound in patients undergoing surgery for non-cystic lesions of the
pancreas. Schlachterman A , Perbtani Y, Williamson JB, Draganov P, Gupte A, Wagh M, Forsmark C
and Chauhan S. DDW 2014- submission
Impact of Pre-Operative Endoscopic Ultrasound in Diagnosis of Cystic Lesions of the Pancreas. Perbtani
Y, Schlachterman A , Williamson JB, Draganov P, Gupte A, Wagh M, Forsmark C and Chauhan S.
DDW 2014- submission
Current and Future Treatments for Hepatocellular Carcinoma. A. Schlachterman, W. Craft, E.
Hilgenfeldt, A. Mitra and R. Cabrera. Review article, World Journal of Gastroenterology- submission
Hepatitis C: treatment considerations in the difficult to treat patient. E.Hilgenfeldt, A. Schlachterman,
R.Firpi. Invited Review.

4. Alexander Schlachterman
alexschlach@gmail.com
215 450 9390
Presentations
Oral International Society on Thrombosis and Haemostasis, Factor V Leiden as a Modifier of Severe
Hemophilia Phenotype in Murine Models. Schlachterman, A., Liu, J., Fergusi, C., Schuettrumpf,
J. and Arruda, V.R.., Sydney, Austalia., August 2005.
Oral American Society of Gene Therapy, Assessing Hemostatic Efficacy of Continuous Expression of
Factor VIIa after AAV-Mediated, Liver-Directed Gene Transfer in Hemophilia A and B mice.
Schlachterman, A. and High, K.A., St. Louis, MO., June 2005.
Oral American Society of Hematology, In Vivo Evidence of Modulation of the Hemophilia Phenotype
by the Factor V Leiden. Schlachterman, A., Liu, J., Fergusi, C., Schuettrumpf, J. and Arruda,
V.R.,San Diego, CA., December 2004.
Oral Hemostasis, Thrombosis and Artherosclerosis Workshop, Thomas Jefferson University School of
Medicine, In Vivo Evidence of Modulation of the Hemophilia Phenotype by the Factor V Leiden.
Schlachterman, A., Liu, J., Fergusi, C., Schuettrumpf, J. and Arruda, V.R.., Philadelphia, PA.,
November 2004.
Poster American Pancreatic Association. Impact of preoperative EUS in patients undergoing surgery for
solid and cystic lesions of the pancreas. Schlachterman A, Perbtani Y, Williamson JB and S.
Chauhan S. Big Island-Kona, Hawaii, November 8, 2014.
Poster American College of Gastroenterology, Iatrogenic Duodenal Perforation Treated with
Endoscopic Placement of Metallic Clips. Schlachterman A, Solomon M, Dekki G and
Morgenstern R. San Diego, CA, October 2013.
Poster American College of Gastroenterology, High-grade Dysplastic Villous Adenoma Arising from
Barrett’s Esophagus. Schlachterman A, Yang D, Collin D and Gupte A., Philadelphia, PA,
October 2014.
Poster Digestive Disease Week, Comparison of Internal Medicine Residents to GI Fellows in the
Assessment of Patients with GI bleeding at an Inner-City University Teaching Hospital: Are
Patients Triaged Appropriately? Schlachterman, A., Priti Bijpuria and Ahmad, A., San Diego,
May 22, 2012.
Poster Discovery Day-Research Day, Drexel University College of Medicine, Colonoscopy in HIV
Population,Retrospective ChartReview., Schlachterman, A., Matin, A., Ousteky, D., Naples, S.,
and Ringold, D., Philadelphia, PA, October 6, 2011
Poster Pennsylvania Society of Gastroenterology, Colonoscopy in HIV Population, Retrospective Chart
Review., Schlachterman, A., Matin, A., Ousteky, D., Naples, S., and Ringold, D., Bedford,
Pennsylvania, September 24, 2011.
Poster Digestive Disease Week, Colonoscopy in HIV Population, Retrospective Chart Review.,
Schlachterman, A., Matin, A., Ousteky, D., Naples, S., and Ringold, D., Chicago, May 10, 2011.
Poster Discovery Day-Research Day, Drexel University College of Medicine, Gastrointestinal Morbidity
following Crack-Cocaine Use: Clinical Observation., Schlachterman, A. and Nunez, A.
Philadelphia, Pennsylvania, October, 2010.
Poster Research Centers in Minority Institutions, Prevention of Breast Cancer Progression by Grape
Polyphenols. Schlachterman, A., Valle F., Morell, L., Azios, N.G., Cubano, L.A. and
Dharmawardhane, S., San Juan, Puerto Rico, January, 2006.
Poster Universidad Central del Caribe Medical School Scientific Investigation Symposium,Prevention of

5. Alexander Schlachterman
alexschlach@gmail.com
215 450 9390
Breast Cancer Progression by Grape Polyphenols. Schlachterman, A.,Valle F., Morell, L.,
Azios, N.G., Cubano, L.A. and Dharmawardhane, S., Bayamon, Puerto Rico. April 20, 2007.,
2007.
Poster Children’s Hospital of Philadelphia Fellow’s Research Poster Day, Factor V Leiden as a Modifier
of Severe Hemophilia Phenotype in Murine Models. Schlachterman, A., Liu, J., Fergusi, C.,
Schuettrumpf, J. and Arruda, V.R., Philadelphia, PA., February 2005.
Poster American Society of Hematology, Assessing Hemostatic Efficacy of Continous Expression of
Factor VIIa Following Administration of AAV Vectors into Hemophilia B Mice. Schlachterman,
A., Liu, J., and High, K.A.. San Diego, CA., December 2004.
Awards
James H. Johnson, MD Scholarship Award, Florida Gastroenterologic Society, September 12-14, 2014,
Boca Raton, FL.
Resident of the month January 2011, Drexel Internal Medicine, Hahnemann University Hospital.
Pennsylvania Society of Gastroenterology September 2011, 3rd
place Poster Presentation. Colonoscopy in
HIV Population, Retrospective Chart Review.
Drexel Research Day 2011, 3rd
place Poster Presentation. Colonoscopy in HIV Population, Retrospective
Chart Review.
Saris Family Parents in Medicine Award. Drexel University College of Medicine, Philadelphia, PA,
November 11, 2010.
UCC 2nd
Scientific Investigation Symposium. First prize cash award. Red wine polyphenols reduce breast
tumor growth in a nude mouse model. Bayamon, Puerto Rico., April 20, 2007.
Young Investigator Award from The International Society on Thrombosis and Haemostasis XXth
Congress, Factor V Leiden as a Modifier of Severe Hemophilia Phenotype in Murine Models. Sydney,
Austalia., August 2005.
Travel Awards from The American Society of Hematology , Assessing Hemostatic Efficacy of
Continous Expression of Factor VIIa Following Administration of AAV Vectors into Hemophilia B Mice.
San Diego, CA., December 2004.
Peer Review Abstract Publications:
Hilgenfeldt E, Schlachterman A, and Wagh M. Pneumopericardium as the presenting sign of esophageal
fistula following atrial ablation. American College of Gastroenterology 2014, Philadelphia
Khullar V, Schlachterman A and Sharma A., Stent or No Stent: Aortoesophageal Fistula from swallowing a
fish bone. American College of Gastroenterology 2014, Philadelphia
Ivanciu, L., Toso, R., Schlachterman, A., Downey, B.S., Liu, J-H., Arruda, V.R., and Camire,
R.M. Zymogen-like factor Xa variants improve hemostasis in hemophilia mice. XXIIth
Congress of the
International Society on Thrombosis and Haemostasis, July 11-16, 2009 Boston, MA. Journal of
Thrombosis and Haemostasis 2009; 7; Supplement 2, (Abstract #AS-TH-013)
Ivanciu, L., Toso, R., Schlachterman, A., Downey, B.S., Liu, J-H., Arruda, V.R., and Camire, R.M.
Factor Xa variants as novel bypass agents for the treatment of hemophilia in murine models. 50th
Annual
Meeting of the American Society of Hematology, December 6-9, 2008 San Francisco, CA. Blood
Supplement 2008, 112 (Abstract #239)

6. Alexander Schlachterman
alexschlach@gmail.com
215 450 9390
Schlachterman, A., Valle, F., Wall, K., Azios, N., Cubano, L., Washington, V. and Dharmawardhane. S.
Prevention of Breast Cancer Progression by Grape Polyphenols. Research Centers in Minority
Institutions/Universidad Central Del Caribe, December 2006.
Aljamali, M., Schlachterman, A., Margaritis, P., Arruda, V., Dunn, D., Ware, J. and High, K.A. Gene
Transfer-mediated Expression of Murine Factor VIIa Improves Clot Formation in a Mouse Model for
Bernard-Soulier Syndrome. American Society of Gene Therapy, June 2006.
Schuettrumpf, J., Schalchterman, A., Zou, J., Furguia, C., Baila, S. and Arruda. V.. Assessing the Role of
Continuous Activated Protein C (APC) Expression in Murine Thrombosis Models American Society of
Hemotolgy, December 2005.
Chu, K., Schlachterman, A., and High. K.A.. Characterization and Gene Silencing of a Novol Gla-
containing Protein. International Society of Thrombosis and Haemostais, Sydney, August 2005.
Alexander Schlachterman, J. Liu, P. Margaritis & K. High.. Assessing Hemostatic Efficacy of Continous
Expression of Factor VIIa After AAV-Mediated, Liver-Directed Gene Transfer In Hemophilia A and B
Mice. American Society of Gene Therapy, June 2005.
J.Schuettrumpf, A. Schalchterman, J. Zou, J. Liu, C Furguia and V. Arruda.. Antithrombotic Effects of
Endogenous Expressed Activated Protein C (aPC) in Murine Models. American Society of Gene Therapy,
June 2005.
Chen, J., Hsu, H., Schlachterman, A., High, K.A., and Mountz. J. Determination of Specific Th1 ans Th2
CD4 T Cell Responces in AAV2- and AAV8-Mediated Human Factor IX Gene Therapy in Mice. American
Society of Gene Therapy, June 2005.
Chen, J., Hsu, H., Schlachterman, A., High, K.A. and Mountz. J.. Cytotoxic T Lymphocyte Response to
AAV2- ans AAV8-Mediated Human Factor IX Gene Therapy in Mice. American Society of Gene Therapy,
June 2005.
Hsieh, M., Khazi, F., Schlachterman, A., Liu, Y. and High, K.A. Persistance of AAV capsid In
Transduced Cells. American Society of Gene Therapy, June 2005.
AAV-Mediated Gene Transfer to Endothelial Cells. Mo-Ying Hsieh, Yi-Lin Liu, Alexander
Schlachterman and Katherine High. American Society of Gene Therapy, June 2005.
Analysis of AAV integration events by ligation mediated PCR. Khazi, FR, Schlachterman, A and High,
KA. American Society of Gene Therapy, June 2005.
rAAV2 Integration Junctions Isolated without In Vivo Selection Bias Show a Preference to 5’ Regions of
Open Reading Frames Khazi, FR, Schlachterman, A and High, KA.. American Society of Gene Therapy,
June 2005.
Effects of hyperbaric oxygen exposure on experimental head and neck tumor growth, oxygenation, and
vasculature. Shi Y, Schlachterman A, Lee CS, Wu J, Koch CJ, Thom SR, Maity A, Bernhard EJ. Head
Neck. 2005.
Assessing Hemostatic Efficacy of Continous Expression of Factor VIIa Following Administration of AAV
Vectors into Hemophilia B Mice. Alexander Schlachterman, Jinhua Liu, Majed Aljamali, & Katherine A.
High.. American Society of Hemotolgy, December 2004.
In Vivo Evidence of Modulation of the Hemophilia Phenotype by the Factor V Leiden Alexander
Schlachterman, Jinhua Liu, Yi-Lin Liu, Katherine A. High, MD & Valder Arruda MD, PhD.. American
Society of Hemotolgy, December 2004.

7. Alexander Schlachterman
alexschlach@gmail.com
215 450 9390
A Novel Deletion in the Fviii B-Domain That Reduces Transgene Size While Preserving FVIII Activity. Yi-
Lin Liu, Hua Zhu, Alexander Schlachterman, Heesoon Chang, Rodney M. Camire, and Katherine A.
High. Blood, American Society of Hemotolgy, 104: 3182, 2004.
Duration of Immunologically Detectable AAV-2 Capsid in an Animal Model. Sabatino DE, Mingozzi F,
Brooks DC, Schlachterman A, Edmonson S, Couto L, Colosi P, Chen H, Ertl HCJ and K.A. High.
American Society of Gene Therapy, Molecular Therapy 9:S16. May 2004.
Animal Model of Transient Transaminitis and Diminished Factor IX Expression Following AAV-Mediated,
Liver-Directed Gene Transfer for Hemophilia B. Sabatino DE, Brooks DC, Schlachterman A, Liu YL,
Chen H, Colosi P, Couto L, and KA High. American Society of Hematology, Blood 102: 493a. 2003.
Development of Peripheral Tolerance ‘Neo-Self’ Skin Grafts Resulting from T Cell Ignorance. Alexander
Schlachterman, Alison Reed, Clyde F. Barker, Ali Naji and Hooman Noorchashm. American Journal of
Transplantation, Vol. 2(S3) Abs 424. 249-276, April 2002.
Engineered Reduction of Thymic T Cell Production Rate Promotes the Development of Peripheral
Tolerance to Skin Allographs. Alison Reed, Alexander Schlachterman, Yasaman Zarrabi, Clyde F.
Barker, Ali Naji and Hooman Noorchashm. American Journal of Transplantation Vol. 2(S3) Abs 466. 249-
276, April 2002.