Myocardial infarction, or heart attack, is a leading cause of death in the United States, with about one million people experiencing an MI each year. The risk of death from a STEMI, a type of heart attack, is around 10% in developed countries. An MI occurs when a plaque in the coronary arteries ruptures, blocking blood flow. Chest pain is the most common symptom of a heart attack, though it can present atypically in some groups. Signs of a heart attack include changes in vital signs, heart sounds, and ECG findings. The immediate treatment for a suspected heart attack includes oxygen, nitrates, aspirin, and morphine to relieve pain and open blood vessels.