This document summarizes different types of urticaria (hives), angioedema, drug eruptions, and erythema multiforme. It describes the characteristics of acute and chronic urticaria, physical urticaria, urticarial vasculitis, and contact urticaria. It also discusses erythema multiforme, Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum, fixed drug eruptions, exanthematous drug eruptions, and drug hypersensitivity syndrome. Treatment options are provided for many of these conditions.
11. AUTOIMMUNE URTICARIA
• Due autoantibodies against FC€R1 receptors or to IgE bound
to the same receptor
• Lead to cross linking of 2 adjacent FC€R1 receptors and mast
cell degranulation
15. CONTACT URTICARIA
• ALLERGIC allergen
penetrate (eg.oral allergy syn)
• NON ALLERGIC by
direct injection of vasoactive chemicals by plants(eg.nettles)
or animals(eg.caterpillars)
18. ERYTHEMA MULTIFORME
• young age
• Mainly by infecton & drugs
• MCC- herpes simplex infection
• Extremities & face
• Mucosa may be involved
• Subsides in few weeks
• Typical lesion- target lesion
19.
20.
21.
22. Target / iris lesion
• 3 ZONES
CENTRAL- dusky violaceous
erythema/blister/necrosis
MIDDLE- pale edematous
OUTER-erythema