3. Where are they most
common
PAH are commonly found in developing
and third world countries.
They are the most widespread harmful
Pollutants.
China’s large population and low income
rate creates a large group of cheap labor.
Which in turn leads to the use of
Coal not only as a source of cheap electricity
But heat as well.
4. Molecular Epidemiology
Frederica Perera helped pioneer
The field of Molecular Epidemiology.
Molecular Epidemiology which applies
Molecular Analysis to genetic and
environmental factors.
5. Risk Factors
When PAH bonds with DNA
They can cause a stunt in
Development. Such as
Smaller heads and scoring
Worse on tests related to
Physical and mental develop.
Children born in areas with high PAH
Were more likely to develop some cancers.
Also PAH increases the number of adducts
In your body.
6. White Blood Cells
PAH also affect s the amount of white blood
Cells in the body. Because the PAH bonds to them .
PAH –DNA adducts promote or suppress
The likely hood of a disease. This supports the
Theory that PAH could cause cancer.
7. Bonding of PAH and DNA
PAH is so harmful because
It can form covalent bonds
Which helps adhere to any
Other molecule.
When it adheres to DNA it
Can leave a fingerprint
Which can be traced back to
The formation of the covalent
Bond.
8. Adducts
Adducts are formed when PAH and DNA
Bonds to form PAH-DNA adducts.
Once adducts are formed the PAH can cause
The genetic code to deteorate and break down.
This can cause the promotion or suppression of
A disease which was stated in slide 7.
9. What you can do
You can help lower PAH levels around you by
Not smoking, lowering your electricity use,
And trying not to have many barbecues.