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Prevention of Heart Disease
Raj
What is Heart Disease?
• Heart : The most hard-working muscle of
our body – pumps 4-5 litres of blood every
minute during rest
• Supplies nutrients and oxygen rich blood to
all body parts, including itself
• Coronary arteries
surrounding the heart
keep it nourished with
blood
What is Atherosclerosis
what is coronary artery disease?

• Over time, fatty deposits called plaque build up within the artery
walls. The artery becomes narrow. This is atherosclerosis
• When this occurs in the coronary arteries, heart does not get
sufficient blood, the condition is called coronary artery disease,
or coronary heart disease
Myth : fat deposits at old age!
It starts from 2 years of Complicated
age

Foam
Cells

Fatty
Streak

From First
Decade

Intermediate
Lesion
Atheroma

From Third
Decade

Adapted from Pepine CJ. Am J Cardiol. 1998;82(suppl 104).

Fibrous
Plaque

Lesion/
Rupture

From Fourth
Decade
Are Other organs Affected?

Ischemic Stroke
Coronary Heart Disease
• Angina
• MI (Heart Attack)
• Sudden Cardiac Death

Peripheral Vascular
Disease
What are the symptoms of
Coronary artery disease?
• No symptoms for long period
• Chest pain for short period on exertion
also known as Angina or minor heart
attack
• Myocardial Infarction or major heart
attack-Severe chest pain, death of
heart muscle, heart failure, irregular
heart beats
• Sudden Death
How Big is the Problem ?
• No. 1 killer disease worldwide
– 12 Million deaths annually

• During last 30 years large declines in
developed countries -rising health
awareness and government
programmes
• Alarming increase in developing
countries especially India
Why Should I (Indian) be Worried ?
• Indians More susceptible that any other ethnic
group
– 3.4 times more than Americans
– 6 times more than Chinese
– 20 times more than Japanese
– Occurs at lower cholesterol

• Get the disease at much younger age
– 5-10 years earlier than other communities

• Disease follows more severe and malignant course
– 3 times higher rate of second heart attack and two times
higher mortality than whites
Why Me ?
• Genetic predisposition
• Poor handling of fats and metabolic
syndrome
– Diabetes, obesity, high BP, Coronary artery
disease

Environmental insults
• Urbanization
• Sudden change in lifestyle
What Increases Risk?
You can’t help it !
• Age:
Men > 45;
Women > 55

• Sex
• Race
• Family History

You can !!
• High Cholesterol
• Smoking
• High Blood Pressure
• Diabetes
• Obesity
• Alcohol
• Physical Inactivity
Cholesterol ( A type of fat)
• Everybody needs cholesterol, it serves
a vital function in the body.
• It circulates in the blood.
• Too much cholesterol
can deposit in the
arteries in the form of
plaque and block them
• No symptoms till heart
attack
Where does it come from ?
65%

• Two sources of
cholesterol: Food
& made in your
body
• Food sources: All
foods containing
animal fat and meat
products

35%
Good vs. BAD Cholesterol
• LDL cholesterol is known as bad
cholesterol. It has a tendency to
increase risk of heart disease
• LDL cholesterol is a major component
of the plaque that clogs arteries
• HDL cholesterol is known as the good
cholesterol. Higher in women,
increases with exercise
• HDL cholesterol helps carry some of
the bad cholesterol out of arteries.
Obesity
• People who are overweight (10-30 % more
than their normal body weight)
• Obese have 2 to 6 times the risk of
developing heart disease
• Normal Waist-Hip Ratio
< 0.85 for women;
< 0.95 for men

• Pears or apples?
Pears and Apples
Apple- shaped are at a higher risk
Pear-shaped paunch store fat on the
hips and thighs, just below the surface of
the skin.
Apple-shaped paunch store body fat
around the abdomen and chest,
surrounding internal organs
Physical Inactivity

Every morning my brain
tells me to exercise…
….. and my body
laughs at the idea
Cigarette Smoking
•
•
•
•
•

Increases blood pressure
Decreases HDL
Damages arteries and blood cells
Increases heart attacks
Cigarette smoke contains more than
4,000 chemicals, and 200 of these
chemicals are poisonous
Cigarette Smoking
If you think YOU are smoking the cigarette, you are mistaken…
It’s the other way round !
Alcohol Consumption
• In small amounts it is beneficial: 1-2
drinks
• In large amounts it adds fat and
calories & raises BP!
• 4 drinks per day. You end up with
gastroenterologist instead of
cardiologist
• This is a very fine line! Finer for
women as they are at higher risk
Diabetes
• At any given cholesterol level, diabetic
persons have a 2 or 3 x higher risk of heart
attack or stroke
• A diabetic is more likely to die of a heart
attack than a non-diabetic
• ~80% Diabetics die from heart disease
• Risk of sudden death from a heart attack
for a diabetic is the same as that of
someone who has already had a heart
attack.
Interactions of Risk Factors
Risk operates across a continuum - no clearcut line
(Blood Pressure; Cholesterol; overweight; Smoking)
The risk is multiplicative when many risk factors coexist; risk factors often cluster together
Majority of events arise in individuals with modest
elevations of many risk factors than from marked
elevation of a single risk factor
Misfortunes always come in
by a door that has been left
open for them.
Czechoslovakian proverb
Everyday you make choices to try to
help protect yourself and your family.
In fact, protecting yourself has
become second nature—you just do
it.
But do you know what you can do to
help protect yourself from this
number 1 cause of death- Heart
Disease?
For my car, I want the best
mechanic.
But for my own body, I follow
hearsay and advice from friends,
kitty party, local quacks….
Just anyone
And decide for the worst
Creative strategies do not work !
• Karva Chauth!
• Never had a test or retest
• Never been to Doctor !
I hate them
• Never take medicines!
• My BP is normal, so stopped
meds!
• Miracle men and Miracle
Medicines! So many of them
• I am my own doctor! No fees
too
Preventing Heart Disease

Rule #1 Look before your eat
• Eat a variety of fruits and vegetables every day.
(5 servings - they are naturally low in fat and
high in vitamins and minerals and anti
oxidants). Eat colored vegetables and fruits
• Eat a variety of grain products
• Choose nonfat or low-fat products.
• Use less fat meats- chicken, fish and lean cuts
 Switch to fat-free milk—toned/skimmed milk
Dietary Guidelines
• Limit your intake of foods high in
calories and low in nutrition, including
foods like soft drinks, candy, junk food
• Limit foods high in saturated fat, transfat and cholesterol
• Eat less than 6 gms of salt a day
• Have no more than1-2 alcoholic drink a
day if you are a regular drinker
Limit / Avoid
• Foods rich in Cholesterol and Saturated
fats
–
–
–
–

Egg Yolk
Fatty meat & organ meat( Liver)
Butter chicken / Batter fried fish !
Milk fat – Desi Ghee, Butter, Cheese,
Malai, Rabri, Khurchan, Doda, Ice Cream,
full cream milk,
– Hidden Fat like Bakery biscuits, Patties (!),
Cakes, Pastries,
Cooking Oils: The mystery of
PUFA / MUFA
• Saturated Fats : Increase Cholesterol – Avoid
– Coconut oil, Palm oil, Vanaspati ghee

• Monounsaturated Fats (MUFA): Heart healthy
– Olive oil, Groundnut oil, Canola oil, Mustard oil

• Polyunsaturated Fats (PUFA): Heart healthy
– Sunflower oil, Soybean oil

• Omega-3-Fatty acids Fish oil : Heart Healthy
Rotate the oils or Mixture of oils
Preventing Heart Disease

Rule #2 Exercise
• Maintain a level of physical activity that
keeps you fit and matches the calories
you eat
• Serves several functions in preventing
and treating those at high risk
• Reduces incidence of obesity
• Increases HDL
• Lowers LDL and total cholesterol
• Helps control diabetes and hypertension
Exercise, Exercise, Exercise
• Mortality is halved in retired men who walk
more than two miles every day
• Regular exercise can halve the risk of heart
disease, particularly in men who walk briskly
• Someone who is inactive has as great a risk of
having heart disease as someone who
smokes, has high blood pressure or has high
cholesterol
• Exercise significantly reduces the chances of
diabetes and stroke
• With regular exercise, blood pressure in those
with hypertension is reduced by as much as
20mms Hg
Exercise and Heart Disease
Moderate to intense physical activity for 30-45
minutes on most days of the week is recommended
Walking for a healthy heart
• Complicated exercise machines or
sweating it out in the gym not essential

JUST WALK!
Rule # 3 Stop Smoking NOW!
• The risk of heart attack starts decreasing
within 24 hours of quitting smoking, within
1 year of quitting, CHD risk decreases
significantly, within 2 years it reaches the
level of a nonsmoker
• Smell and taste improve within days
• Within three months of quitting, the
smokers' cough disappears in most people
Rule # 3 Stop Smoking NOW!
Benefits much beyond Heart Disease
Tobacco
Diet
Physical Activity

Cardiovascular
Cancers
Diabetes
Chronic Respiratory Diseases
Osteoporosis

Alcohol

Oral Health
Mental Health
Rule # 4 Know your Number!
And that’s not your Mobile Number!

Desirable numbers
• Total cholesterol < 200;
• LDL < 100
• HDL > 40
• triglycerides < 200
• Get the levels tested routinely and keep them
under control
• The only thing worse than finding out that
you have one of these conditions is…….NOT
finding out that you have it!!
Benefits of reducing
cholesterol
10% reduction of blood
cholesterol produces 20-30%
decline in CHD deaths
All Adults >20 yrs must get tested- if normal test again
after 5 years, if elevated, work towards normalizing the
levels with lifestyle modification and drugs as needed
Controlling Blood Pressure
• Adults should have their blood pressure
checked at least once every two years, as
there are no symptoms to tell if you have
high blood pressure
• Optimal levels : 120 /80 mm Hg
• If high
– Modify your lifestyle – Diet, Weight, Exercise,
Salt restriction
– Adhere to the prescribed medication without fail,
to decrease chances of getting heart disease – Do
not stop your medicines without consulting your
doctor, even if the blood pressure becomes normal
Controlling Blood Sugar
• All adults should have their blood sugar
checked regularly, as there are no early
symptoms of diabetes
• Normal blood sugar:
• Fasting < 100; post meals <140
• If high
– Modify your lifestyle – Diet, Weight, Exercise
– Adhere to the prescribed medication without fail,
to decrease chances of getting heart disease – Do
not stop your medicines without consulting your
doctor, even if the blood sugar becomes normal
If you or someone in your family
already diagnosed with heart disease
• Don’t get disheartened – science has made
significant progress
• Just monitor risk factors much more aggressively
– Eat healthy
– Walk regularly
– Watch your weight
– Quit smoking immediately
– Keep your weight under control
– In addition to improving your heart – health these measures
are sure to enhance your appearance !!

• Adhere to you medicines & listen to your doctor
Don’t wait for a heart attack to take
an action !

Don’t wait for a second life we
are not cats!
Heart disease is often avoidable. Following a hearthealthy lifestyle doesn't have to be complicated, and it
doesn't mean you need to live a life of self-deprivation.
Instead, find ways to incorporate heart-healthy habits
into your lifestyle — and you may well enjoy a healthier
life for years to come.

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Prevention of heart disease

  • 1. Prevention of Heart Disease Raj
  • 2. What is Heart Disease? • Heart : The most hard-working muscle of our body – pumps 4-5 litres of blood every minute during rest • Supplies nutrients and oxygen rich blood to all body parts, including itself • Coronary arteries surrounding the heart keep it nourished with blood
  • 3. What is Atherosclerosis what is coronary artery disease? • Over time, fatty deposits called plaque build up within the artery walls. The artery becomes narrow. This is atherosclerosis • When this occurs in the coronary arteries, heart does not get sufficient blood, the condition is called coronary artery disease, or coronary heart disease
  • 4. Myth : fat deposits at old age! It starts from 2 years of Complicated age Foam Cells Fatty Streak From First Decade Intermediate Lesion Atheroma From Third Decade Adapted from Pepine CJ. Am J Cardiol. 1998;82(suppl 104). Fibrous Plaque Lesion/ Rupture From Fourth Decade
  • 5. Are Other organs Affected? Ischemic Stroke Coronary Heart Disease • Angina • MI (Heart Attack) • Sudden Cardiac Death Peripheral Vascular Disease
  • 6. What are the symptoms of Coronary artery disease? • No symptoms for long period • Chest pain for short period on exertion also known as Angina or minor heart attack • Myocardial Infarction or major heart attack-Severe chest pain, death of heart muscle, heart failure, irregular heart beats • Sudden Death
  • 7. How Big is the Problem ? • No. 1 killer disease worldwide – 12 Million deaths annually • During last 30 years large declines in developed countries -rising health awareness and government programmes • Alarming increase in developing countries especially India
  • 8. Why Should I (Indian) be Worried ? • Indians More susceptible that any other ethnic group – 3.4 times more than Americans – 6 times more than Chinese – 20 times more than Japanese – Occurs at lower cholesterol • Get the disease at much younger age – 5-10 years earlier than other communities • Disease follows more severe and malignant course – 3 times higher rate of second heart attack and two times higher mortality than whites
  • 9. Why Me ? • Genetic predisposition • Poor handling of fats and metabolic syndrome – Diabetes, obesity, high BP, Coronary artery disease Environmental insults • Urbanization • Sudden change in lifestyle
  • 10. What Increases Risk? You can’t help it ! • Age: Men > 45; Women > 55 • Sex • Race • Family History You can !! • High Cholesterol • Smoking • High Blood Pressure • Diabetes • Obesity • Alcohol • Physical Inactivity
  • 11. Cholesterol ( A type of fat) • Everybody needs cholesterol, it serves a vital function in the body. • It circulates in the blood. • Too much cholesterol can deposit in the arteries in the form of plaque and block them • No symptoms till heart attack
  • 12. Where does it come from ? 65% • Two sources of cholesterol: Food & made in your body • Food sources: All foods containing animal fat and meat products 35%
  • 13. Good vs. BAD Cholesterol • LDL cholesterol is known as bad cholesterol. It has a tendency to increase risk of heart disease • LDL cholesterol is a major component of the plaque that clogs arteries • HDL cholesterol is known as the good cholesterol. Higher in women, increases with exercise • HDL cholesterol helps carry some of the bad cholesterol out of arteries.
  • 14. Obesity • People who are overweight (10-30 % more than their normal body weight) • Obese have 2 to 6 times the risk of developing heart disease • Normal Waist-Hip Ratio < 0.85 for women; < 0.95 for men • Pears or apples?
  • 15. Pears and Apples Apple- shaped are at a higher risk Pear-shaped paunch store fat on the hips and thighs, just below the surface of the skin. Apple-shaped paunch store body fat around the abdomen and chest, surrounding internal organs
  • 16. Physical Inactivity Every morning my brain tells me to exercise… ….. and my body laughs at the idea
  • 17. Cigarette Smoking • • • • • Increases blood pressure Decreases HDL Damages arteries and blood cells Increases heart attacks Cigarette smoke contains more than 4,000 chemicals, and 200 of these chemicals are poisonous
  • 18. Cigarette Smoking If you think YOU are smoking the cigarette, you are mistaken… It’s the other way round !
  • 19. Alcohol Consumption • In small amounts it is beneficial: 1-2 drinks • In large amounts it adds fat and calories & raises BP! • 4 drinks per day. You end up with gastroenterologist instead of cardiologist • This is a very fine line! Finer for women as they are at higher risk
  • 20. Diabetes • At any given cholesterol level, diabetic persons have a 2 or 3 x higher risk of heart attack or stroke • A diabetic is more likely to die of a heart attack than a non-diabetic • ~80% Diabetics die from heart disease • Risk of sudden death from a heart attack for a diabetic is the same as that of someone who has already had a heart attack.
  • 21. Interactions of Risk Factors Risk operates across a continuum - no clearcut line (Blood Pressure; Cholesterol; overweight; Smoking) The risk is multiplicative when many risk factors coexist; risk factors often cluster together Majority of events arise in individuals with modest elevations of many risk factors than from marked elevation of a single risk factor
  • 22. Misfortunes always come in by a door that has been left open for them. Czechoslovakian proverb
  • 23. Everyday you make choices to try to help protect yourself and your family. In fact, protecting yourself has become second nature—you just do it. But do you know what you can do to help protect yourself from this number 1 cause of death- Heart Disease?
  • 24. For my car, I want the best mechanic. But for my own body, I follow hearsay and advice from friends, kitty party, local quacks…. Just anyone And decide for the worst
  • 25. Creative strategies do not work ! • Karva Chauth! • Never had a test or retest • Never been to Doctor ! I hate them • Never take medicines! • My BP is normal, so stopped meds! • Miracle men and Miracle Medicines! So many of them • I am my own doctor! No fees too
  • 26. Preventing Heart Disease Rule #1 Look before your eat • Eat a variety of fruits and vegetables every day. (5 servings - they are naturally low in fat and high in vitamins and minerals and anti oxidants). Eat colored vegetables and fruits • Eat a variety of grain products • Choose nonfat or low-fat products. • Use less fat meats- chicken, fish and lean cuts  Switch to fat-free milk—toned/skimmed milk
  • 27. Dietary Guidelines • Limit your intake of foods high in calories and low in nutrition, including foods like soft drinks, candy, junk food • Limit foods high in saturated fat, transfat and cholesterol • Eat less than 6 gms of salt a day • Have no more than1-2 alcoholic drink a day if you are a regular drinker
  • 28. Limit / Avoid • Foods rich in Cholesterol and Saturated fats – – – – Egg Yolk Fatty meat & organ meat( Liver) Butter chicken / Batter fried fish ! Milk fat – Desi Ghee, Butter, Cheese, Malai, Rabri, Khurchan, Doda, Ice Cream, full cream milk, – Hidden Fat like Bakery biscuits, Patties (!), Cakes, Pastries,
  • 29. Cooking Oils: The mystery of PUFA / MUFA • Saturated Fats : Increase Cholesterol – Avoid – Coconut oil, Palm oil, Vanaspati ghee • Monounsaturated Fats (MUFA): Heart healthy – Olive oil, Groundnut oil, Canola oil, Mustard oil • Polyunsaturated Fats (PUFA): Heart healthy – Sunflower oil, Soybean oil • Omega-3-Fatty acids Fish oil : Heart Healthy Rotate the oils or Mixture of oils
  • 30. Preventing Heart Disease Rule #2 Exercise • Maintain a level of physical activity that keeps you fit and matches the calories you eat • Serves several functions in preventing and treating those at high risk • Reduces incidence of obesity • Increases HDL • Lowers LDL and total cholesterol • Helps control diabetes and hypertension
  • 31. Exercise, Exercise, Exercise • Mortality is halved in retired men who walk more than two miles every day • Regular exercise can halve the risk of heart disease, particularly in men who walk briskly • Someone who is inactive has as great a risk of having heart disease as someone who smokes, has high blood pressure or has high cholesterol • Exercise significantly reduces the chances of diabetes and stroke • With regular exercise, blood pressure in those with hypertension is reduced by as much as 20mms Hg
  • 32. Exercise and Heart Disease Moderate to intense physical activity for 30-45 minutes on most days of the week is recommended
  • 33. Walking for a healthy heart • Complicated exercise machines or sweating it out in the gym not essential JUST WALK!
  • 34. Rule # 3 Stop Smoking NOW! • The risk of heart attack starts decreasing within 24 hours of quitting smoking, within 1 year of quitting, CHD risk decreases significantly, within 2 years it reaches the level of a nonsmoker • Smell and taste improve within days • Within three months of quitting, the smokers' cough disappears in most people
  • 35. Rule # 3 Stop Smoking NOW!
  • 36. Benefits much beyond Heart Disease Tobacco Diet Physical Activity Cardiovascular Cancers Diabetes Chronic Respiratory Diseases Osteoporosis Alcohol Oral Health Mental Health
  • 37. Rule # 4 Know your Number! And that’s not your Mobile Number! Desirable numbers • Total cholesterol < 200; • LDL < 100 • HDL > 40 • triglycerides < 200 • Get the levels tested routinely and keep them under control • The only thing worse than finding out that you have one of these conditions is…….NOT finding out that you have it!!
  • 38. Benefits of reducing cholesterol 10% reduction of blood cholesterol produces 20-30% decline in CHD deaths All Adults >20 yrs must get tested- if normal test again after 5 years, if elevated, work towards normalizing the levels with lifestyle modification and drugs as needed
  • 39. Controlling Blood Pressure • Adults should have their blood pressure checked at least once every two years, as there are no symptoms to tell if you have high blood pressure • Optimal levels : 120 /80 mm Hg • If high – Modify your lifestyle – Diet, Weight, Exercise, Salt restriction – Adhere to the prescribed medication without fail, to decrease chances of getting heart disease – Do not stop your medicines without consulting your doctor, even if the blood pressure becomes normal
  • 40. Controlling Blood Sugar • All adults should have their blood sugar checked regularly, as there are no early symptoms of diabetes • Normal blood sugar: • Fasting < 100; post meals <140 • If high – Modify your lifestyle – Diet, Weight, Exercise – Adhere to the prescribed medication without fail, to decrease chances of getting heart disease – Do not stop your medicines without consulting your doctor, even if the blood sugar becomes normal
  • 41. If you or someone in your family already diagnosed with heart disease • Don’t get disheartened – science has made significant progress • Just monitor risk factors much more aggressively – Eat healthy – Walk regularly – Watch your weight – Quit smoking immediately – Keep your weight under control – In addition to improving your heart – health these measures are sure to enhance your appearance !! • Adhere to you medicines & listen to your doctor
  • 42. Don’t wait for a heart attack to take an action ! Don’t wait for a second life we are not cats!
  • 43. Heart disease is often avoidable. Following a hearthealthy lifestyle doesn't have to be complicated, and it doesn't mean you need to live a life of self-deprivation. Instead, find ways to incorporate heart-healthy habits into your lifestyle — and you may well enjoy a healthier life for years to come.

Editor's Notes

  1. Atherosclerosis is a progressive disease involving the development of arterial wall lesions. As they grow, these lesions may narrow or occlude the arterial lumen. Complex lesions may also become unstable and rupture, leading to acute coronary events, such as unstable angina, myocardial infarction, and stroke. Pepine CJ. The effects of angiotensin-converting enzyme inhibition on endothelial dysfunction: potential role in myocardial ischemia. Am J Cardiol. 1998; 82(suppl 10A):244-275.
  2. Cholesterol is a soft waxy substance found among the lipids in the bloodstream and in all of your body’s cells. Everybody needs cholesterol, it serves a vital function in the body. It is a component of the nerve tissue of the brain and spinal cord as well as other major organs. We get cholesterol from two ways. Our bodies make it and the rest comes from animal products we eat. It is frequently measured to promote health and prevent disease. Desirable levels of total cholesterol levels should be at 200 or less. 240 is considered high but it will depend on the HDL and LDL levels if at this level there is a risk to your health. It is a major component of the plaque that clogs arteries. Cholesterol and other fats can’t dissolve in the blood. They have to be transported to and from cells by special carriers called lipoproteins.
  3. People who are obese have 2 to 6 times the risk of developing hypertension even if they have no other risk factors.
  4. Exercise can help control blood cholesterol, diabetes and obesity, as well as help lower blood pressure.
  5. Alcohol Consumption: In small amounts alcohol acts as a vasodilator, this is good and usually occurs in 1-2 drinks. In large amounts it acts as a vasoconstrictor which is bad. The range this occurs is 3-4 drinks. This is a very fine line. Other risk factors that may contribute to a higher risk of heart disease is an individual’s response to stress, sex hormones, and the loss of natural estrogen as women age.
  6. About 2/3 of the people with diabetes die of some type of heart or blood vessel disease.
  7. How can you stop cardiovascular disease? The heart healthy diet is designed to decrease sodium, saturated fat, including trans fatty acids which are all closely linked to high blood cholesterol and an increased risk of heart disease. It also encourages the increased intake of monounsaturated fat, Omega 3 fatty acids and soluble fiber which helps to lower blood cholesterol levels and reduce the risk of heart disease.
  8. Exercise can help control blood cholesterol, diabetes and obesity, as well as help lower blood pressure.
  9. Exercise can help control blood cholesterol, diabetes and obesity, as well as help lower blood pressure.