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Original Article



              Pharmacological and non pharmacological treatment
                 for relief of perineal pain after vaginal delivery
      Tratamento farmacológico e não farmacológico no alívio da dor perineal pós-parto normal
                                                                   Joyce Hasegawa1, Lucila Coca Leventhal2




ABSTRACT                                                                                                  Descritores: Dor; Períneo; Período pós-parto; Analgesia obstétrica;
Objective: To identify the types of pharmacological and non-                                              Parto
pharmacological treatments used during hospitalization, in the relief
of perineal pain after vaginal deliveries. Methods: Data were obtained
from medical files of patients who had vaginal deliveries during 2007.                                    INTRODUCTION
Results: The mean age of mothers was 32.4 years, and 97.7% of                                             Perineal trauma is a significant problem that affects
them suffered perineal trauma. As to treatment for relief of perineal                                     women worldwide who had vaginal deliveries, as it may
pain after a vaginal delivery, 98.5% used drugs, the most frequent of                                     cause pain and discomfort during the postpartum period.
which were non-steroidal anti-inflammatory drugs, and 62.3% of them
                                                                                                          Several factors are responsible for perineal trauma, e.g.,
also used non-drug treatments, especially ice packs. Conclusion:
It is important that healthcare professionals, who attend to new
                                                                                                          size of fetus, poor adaptation of the fetal presentation
puerperas, know how to assess and treat perineal pain. Considering                                        to the pubic symphysis, anomalous fetal positions, and
the high rates of perineal trauma following vaginal deliveries, we need                                   episiotomies(1-2).
to offer patients treatment alternatives for perineal pain, based on                                          Perineal loss of integrity may cause the woman
scientific evidence.                                                                                      postpartum discomfort and may negatively influence
                                                                                                          psychological and physical function, especially pain(3).
Keywords: Pain; Perineum; Postpartum period; Analgesia, obstetrical;                                          In breastfeeding, pain inhibits the release of
Delivery                                                                                                  oxytocin, the hormone responsible for the ejection
                                                                                                          reflex (let-down reflex) and production of breast
                                                                                                          milk. Even when there is a normal production of
RESUMO
                                                                                                          maternal milk, pain, fatigue and anxiety may impede
Objetivo: Identificar os tipos de tratamentos farmacológicos e
                                                                                                          the delivery of milk to the newborn, increasing
não farmacológicos utilizados no alívio da dor perineal após o
parto normal, utilizados pela puérpera no período de internação.                                          maternal anxiety even more and blocking the release
Métodos: Os dados foram obtidos por meio dos prontuários                                                  of oxytocin(4).
médicos de puérperas que tiveram parto normal no ano de 2007.                                                 It is important to point out that there is no reliable
Resultados: A média de idade das puérperas foi de 32,4 anos e                                             evidence that the routine use of the episiotomy has a
97,7% sofreram trauma perineal. Quanto ao tratamento para o alívio                                        beneficial effect. Episiotomies provoke a greater loss
da dor perineal, após o parto normal 98,5% utilizaram fármacos,                                           of blood and increase the incidence of dyspareunia
sendo o anti-inflamatório não esteroidal o mais frequente, e 62,3%                                        and perineal pain after birth. They are indicated in
utilizaram também o tratamento não farmacológico, o fármaco
                                                                                                          situations of fetal distress, large fetuses, prematurity,
mais utilizado foi bolsa de gelo. Conclusão: É importante que os
                                                                                                          if the perineum has little elasticity, or there is vulvar
profissionais que atendem à puérpera, saibam avaliar e tratar a dor
perineal. Considerando as elevadas taxas de traumatismo perineal                                          edema, and the threat of perineal laceration(5-6).
após o parto normal ainda presentes em nossa população, precisa-                                              Among the practices employed to avoid trauma,
se oferecer às puérperas alternativas de tratamento para a dor                                            we mention protection of the perineum and perineal
perineal, com base em evidências científicas.                                                             massage during the final expulsion period(7).

Final paper presented at Faculdade de Enfermagem do Hospital Israelita Albert Einstein – HIAE, São Paulo (SP), Brazil.
	Nurse from Faculdade de Enfermagem do Hospital Israelita Albert Einstein – HIAE, São Paulo (SP), Brasil.
1


	Obstetric nurse; PhD in Obstetric Nursing from Escola de Enfermagem da Universidade de São Paulo – USP; Lecturer at the Child-maternal Nursing Department of Faculdade de Enfermagem of Hospital
2

 Israelita Albert Einstein – HIAE, São Paulo (SP), Brazil.
	 Corresponding author: Lucila Coca Leventhal – Avenida Professor Francisco Morato, 4.293 – Butantã – CEP 05521-200 – São Paulo (SP), Brasil – Tel.: 11 3746-1001 – e-mail: lucila0308@hotmail.com
	 Received on Jan 17, 2009 – Accepted on Mar 12, 2009



einstein. 2009;7(2 Pt 1):194-200
Pharmacological and non pharmacological treatment for relief of perineal pain after vaginal delivery   195



    In an American research study carried out with                physical therapy equipment, such as ultrasound and
1,573 women in the postpartum period, 67% of                      transcutaneous electrical nerve stimulation (TENS)(2).
primiparas without episiotomies and 82.3% of those                    Ultrasound is a device that emits sound waves (16 to
with episiotomies reported perineal pain two weeks                18 kHz) with a frequency of 3 MHz, which is not audible
after birth(8).                                                   to the human ear. It requires continual assistance of the
    The physical factors associated with perineal pain            operator during treatment and; therefore, has a high
interfere in various activities of puerparas, such as             cost relative to the physical therapist’s time. TENS is a
walking, sitting, sleeping, self-care, caring for the             low frequency device (varying from 1 to 250 HZ) that
newborn, appetite, sexual dysfunction, which can lead             sends electrical impulses through the skin. It possesses
to maternal exhaustion and hinder the experience                  significant advantages such as low cost, few side effects,
of maternity, in some cases even leading to marital               and it is effective in decreasing pain and consumption
problems(1).                                                      of analgesics(15-16).
    In a study conducted with puerperas who had vaginal
deliveries in the city of São Paulo, the prevalence of pain
was 96% higher during the first 24 hours, and perineal            OBJECTIVE
pain was the most frequently cited. The women referred            To identify which types of drugs and non-drugs
interference of pain in breastfeeding, sleeping, caring           treatments are used during hospitalization in relief of
for the baby, locomotion, and elimination (voiding and            maternal perineal pain after a vaginal delivery.
evacuating)(9).
    Despite the use of measures to prevent pain, there
are several treatments for relief of perineal pain.               METHODS
Pharmacological and non-pharmacological methods                   This is a quantitative, descriptive, exploratory, and
are used to treat this discomfort(2,10).                          retrospective study. This study was developed at
    According to the Dictionary of Drug Administration            the maternity of Hospital Israelita Albert Einstein
in Nursing, 2007/2008(11), pharmacological pain relief            (HIAE). The maternity has 45 puerperium beds, four
methods include non-steroidal anti-inflammatory drugs,            delivery rooms, four prepartum/delivery/puerperium
oral analgesics, local anesthetics and opioids.                   rooms, three prepartum rooms, and one screening
    Several factors should be considered in oral                  room. During the year 2007, at this hospital there
analgesic preparations, such as intensity of pain,                were 2,931 births; 2,283 (77.9%) of them were by
probability of the medication causing constipation,               caesarian section, 569 were normal (19.3%), and 83
gastric irritation, passage of the drug to maternal milk,         by forceps (2.8%).
and more serious adverse effects, such as prolonged                   From July 3rd to July 11th, 2008, the period during
bleeding time(10).                                                which the authors were available, data were collected
    According to these criteria, paracetamol and                  in medical files. All files of women who had vaginal
ibuprofen are considered the safest ones for use during           deliveries during the period of February 1st to April 29th,
lactation, due to their short time of action and of reports       2007, were analyzed, totaling 130 patient files.
of adverse effects on the newborn(12).                                For this study, an instrument that had been
    For non-pharmacological methods, we have observed             developed by the authors themselves was used,
in practice the use of ice packs, hot compresses, and             with open-ended and closed questions, containing
sitz-baths.                                                       three parts. The first part has identification data of
    Ice packs during the first 24 hours postpartum is a           the women, such as age, level of schooling, marital
traditional method used for the immediate symptomatic             status, among others. The second part was composed
relief of pain since it anesthetizes the perineum, but            of data on gestation and delivery, such as type of
this relief is generally short-lived, and there is no             laceration and newborn birthweight. The third part
evidence of any long-term benefit. After 24 hours, heat           consisted of information on pharmacological and non-
is recommended because it increases circulation to                pharmacological methods of relieving pain used by the
the region. Forms of heat used are hot compresses or              puerpera during hospitalization.
sitz-baths. It helps to reduce perineal edema, to avoid               According to resolution 196/1996 of the National
the formation of hematomas, to relieve discomfort,                Council of Health, the project was approved by the
to promote recovery of the wound by cleaning the                  Ethics in Research Committee of HIAE (Ethics in
perineum and anus, and reduces inflammation(13-14).               Research Committee approval protocol # 842), and
    Recently, new non-drug methods have been                      authorization was requested from this Committee to
investigated for relief of pain. They are composed of             not use the informed consent form.



                                                                                                                                   einstein. 2009;7(2 Pt 1):194-200
196     Hasegawa J, Leventhal LC



    Data were analyzed using descriptive statistics                              Table 2. Data on pregnancy and delivery
and, presented in the form of tables using descriptive                            Data on pregnancy and delivery                             n      %
statistics.                                                                       Gestational age
                                                                                  37 - 41 weeks                                              123   94.6
                                                                                  32 - 36 weeks                                               7     5.4
RESULTS                                                                           Parity
                                                                                  Nullipara                                                  61    46.9
In July 2008, 130 patient medical files of puerperas who                          Primipara                                                  52    40.0
had vaginal deliveries were identified during the period                          Multipara                                                  17    13.1
from February to April 2007.                                                      Anesthesia
    Maternal age varied from 20 to 44 years, and most                             Yes                                                        128   98.5
                                                                                  No                                                          2     1.5
of them were between 20 and 34 years old (90/130;
                                                                                  Perineal trauma
69.2%); the mean was 32.4, the median was 32, and the
                                                                                  Yes                                                        127   97.7
standard deviation, 3.9. Most of them had remunerated                             No                                                          3     2.3
occupations (92.3%), had more than 12 years of                                    NB sex
schooling (98.4%), were married (93.8%), and white                                Female                                                     67    51.5
(96.9%), as can be observed on Table 1.                                           Male                                                       63    48.5
                                                                                  Birth weight
Table 1. Distribution of sociodemographic characteristics of puerperas studied    < 2,500 g                                                    5    3.9
                                                                                  2,500 – 3,500 g                                            103   79.2
 Sociodemographic characteristics                          n             %        ≥ 3,500 g                                                   22   16.9
 Age group (years)                                                               NB: newborn.
 20 – 34 years                                            90            69.2
 ≥ 35 years                                               40            30.8
 Occupation
                                                                                     Table 3 shows that the most widely used drugs
 Remunerated job                                          120           92.3     were non-steroidal anti-inflammatory drugs (91.5%),
 Housewife                                                 10           7.7      followed by oral analgesics (88.5%). Several patients
 Schooling                                                                       had more than one type of drug prescribed.
 8 - 11 years                                              1            0.8
 12 and more years                                        128           98.4
 No record                                                 1            0.8      Table 3. Distribution of pharmacological groups treatment
 Marital status                                                                   Pharmacological treatment                                   n     %
 Married                                                  122           93.8      Non-steroidal anti-inflammatory drugs                      119   91.5
 Single                                                    5            3.9       Oral analgesics                                            115   88.5
 Separated                                                 3            2.3       Local anesthetic                                            71   54.6
 Skin color                                                                       Opioids                                                     21   16.1
 White                                                    126           96.9      Did not use                                                  2    1.6
 Yellow                                                    4            3.1


    According to gestation and delivery data presented                              As to the non-pharmacological treatment (Table 4)
on Table 2, we note that all women of this study had                             used by 81 (62.3%) patients during hospitalization, ice
prenatal accompaniment, with seven or more clinical                              packs were the most frequently used (61.5%), and they
visits (100.0%); most mothers delivered at a gestational                         were prescribed up to six times a day for 20 minutes
age of 37 to 41 weeks (94.6%). As to parity, 46.9% were                          each time. The second most common treatment used
nulliparas, 40.0% primiparas, and 13.1% multiparas;                              was the warm sitz-baths (2.3%), and for some women
80.8% of them had not had abortions/miscarriages in                              more than one non-drug treatment was prescribed.
their other gestations. Most women were anesthetized
(98.5%). In 128 patients anesthetized, the most                                  Table 4. Distribution of non-pharmacological groups treatment
frequent type of anesthesia used was double anesthetic                            Non-pharmacological treatment                              n      %
block (79.7%), followed by rachianesthesia (10.9%)                                Ice packs                                                  80    61.5
and epidural block (9.4%). It was also noted that 127                             Warm sitz-bath                                              3     2.3
(97.7%) puerperas had perineal trauma.                                            Hot compresses                                              1     0.8
                                                                                  Did not use                                                49    37.7
    As to data on newborns, most were female (51.5%),
with predominant weight between 2,500 to 3,500 g
(79.2%), as presented on Table 2.                                                    Table 5 shows a high percentage of use of non-
    Of the 130 medical files selected, 98.5% women                               steroidal anti-inflammatory drugs, especially in women
used pharmacological treatment and 62.3% used non-                               with newborns weighing more than 3,500 g. The use of
pharmacological treatment.                                                       opioids was also greater (27.3%) among these patients.


einstein. 2009;7(2 Pt 1):194-200
Pharmacological and non pharmacological treatment for relief of perineal pain after vaginal delivery   197



Table 5. Distribution of women who used pharmacological and non-pharmacological         Table 7. Distribution of women who used pharmacological and non-pharmacological
treatment per newborn birth weight                                                      treatment per parity
 NB weight                 NB < 2,500 g NB 2,500 – 3,500 g NB > 3,500 g                  Parity                                           Nulliparas       Primiparas Multiparas
 Pharmacological                                                                         Pharmacological treatment                           n (%)            n (%)      n (%)
                               n (%)                 n (%)          n (%)
 treatment                                                                               Non-steroidal anti-inflammatory drugs             56 (91.8)        48 (92.3)  15 (88.2)
 Non-steroidal anti-          4 (80.0)              94 (91.3)      21 (95.4)             Oral analgesics                                   54 (88.5)        45 (86.5)  16 (94.1)
 inflammatory drugs                                                                      Local anesthetics                                 42 (68.8)        23 (44.2)   6 (35.3)
 Oral analgesics              4 (80.0)              90 (87.4)      21 (95.4)             Opioids                                            8 (13.1)        11 (21.5)   2 (11.7)
 Local anesthetics            3 (60.0)              59 (57.3)      9 (40.9)              Did not use                                        1 (1.6)          1 (1.9)        -
 Opioids                          -                 15 (14.5)      6 (27.3)              Non-pharmacological treatment
 Did not use                  1 (20.0)               1 (0.9)           -                 Ice pack                                          42 (68.8)        31 (59.6)          7 (41.2)
 Non-pharmacological treatment                                                           Warm sitz-bath                                         -            3 (5.7)               -
 Ice pack                 4 (80.0)                  62 (47.7)      14 (63.6)             Hot compresses                                     1 (1.6)              -                 -
 Warm sitz-bath               -                     2 (1.94)        1 (4.5)              Did not use                                       17 (27.8)        20 (38.5)         12 (70.6)
 Hot compresses               -                         -           1 (4.5)              Total                                             61 (100.0)       52 (100.0)       17 (100.0)
 Did not use              1 (20.0)                  41 (31.5)      7 (31.8)
 Total                    5 (100.0)                103 (100.0)    22 (100.0)
                                                                                        medical files from which we collected data, there were
NB: newborn
                                                                                        nursing notes about perineal pain, but these annotations
                                                                                        referred only to the presence or absence of the algesic
As to the non-drug treatment, ice-packs were the most
                                                                                        complaint. No record was found as to the application of
frequently used in the three groups.
                                                                                        a pain scale, report of improvement or worsening of the
    According to the type of trauma, as shown on
                                                                                        pain and/or of any interference of pain in breastfeeding,
Table 6, women with episiotomies were those who most
                                                                                        in caring for the newborn, in sleeping, or in walking,
used a non-steroidal anti-inflammatory drug (94.6%);
                                                                                        among others.
patients with lacerations usually used ice packs.
                                                                                            In a study carried out in maternities in the city of
                                                                                        Belo Horizonte, the prescription of analgesics was noted
Table 6. Distribution of women who used pharmacological and non-pharmacological         in 75.5%, and of non-steroidal anti-inflammatories in
treatment per type of trauma
                                                                                        77.8%, in the immediate postpartum period, and more
 Type of trauma                     Episiotomy Laceration Intact perineum               than one medication was prescribed simultaneously(17).
 Pharmacological treatment             n (%)     n (%)          n (%)
                                                                                        This shows the high rate of drugs prescribed for relief
 Non-steroidal anti-inflammatory     106 (94.6) 11 (73.3)     2 (66.7)
 drugs                                                                                  of pain.
 Oral analgesics                       99 (88.4)      14 (93.3)   2 (66.7)                  In the present study, among pharmacological
 Local anesthetics                     66 (59.2)      3 (20.0)    2 (66.7)              treatments used, we noted that non-steroidal anti-
 Opioids                               19 (17.0)       1 (6.7)    1 (33.3)              inflammatories were the most frequently used drugs
 Did not use                            1 (0.9)           -       1 (33.3)              in most cases. They make up the largest group of
 Non-pharmacological treatment                                                          analgesics, have moderate potency, and are widely used
 Ice pack                       65 (58.8)             14 (93.3)    1 (33.3)             in prevention and treatment of postoperative pain(18).
 Warm sitz-bath                  1 (0.9)              2 (14.3)         -                    The non-steroidal anti-inflammatory drugs are
 Hot compresses                  1 (0.9)                  -            -                among the drugs most often used by patients. However,
 Did not use                    46 (41.1)              1 (6.7)     2 (66.7)
                                                                                        among the 27 non-steroidal anti-inflammatories
 Total                         112 (100.0)           15 (100.0)   3 (100.0)
                                                                                        marketed in Brazil, only 14 contained references to
                                                                                        safety for use during breastfeeding(12,17).
    Regarding parity, as per Table 7, high indices were                                     Oral analgesics were the second most frequently
noted of the use of drugs in all three categories. However,                             used drug in this study. A bibliographic review with the
nulliparas (68.8%) utilized more local anesthetics than                                 objective of assessing analgesic efficacy and adverse
did primiparas (44.2%) and multiparas (35.3%). The                                      effects of a single dose of dipyrone for acute postoperative
use of ice was also more frequently present among the                                   pain, showed that dipyrone has efficacy similar to that of
nulliparas.                                                                             ibuprofen (400 mg) and other analgesics often used to
                                                                                        treat moderate to intense postoperative pain. The most
                                                                                        common adverse effects were somnolence, stomach
DISCUSSION                                                                              upsets, and nausea(19).
In the present study, we noted that a large number                                          The third most commonly used drug in this study
of puerperas used pharmacological and non-                                              was local anesthetic. A bibliographic review composed
pharmacological treatments for the relief of pain during                                of 976 women, with the objective of evaluating the
the postpartum period of hospitalization. In many                                       effects of topically applied anesthetics in postpartum


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198     Hasegawa J, Leventhal LC



perineal pain showed no significant differences in pain        The study was composed of patients who underwent
relief when the topic anesthetic was compared to the           instrumentation during vaginal delivery. After 48
topical use of a placebo(1).                                   hours postpartum, a statistically significant difference
     When pain passes the most intense level, codeine          was found in reduction of edema, hematomas and
derivatives are used, but they should be employed for          pain. This was greater in the group that used the new
short durations, since prolonged use predisposes toward        treatment. The authors point out that it is likely that
constipation, which is particularly important to avoid in      the results of the new treatment were significant, since
treatment of perineal pain(10,20).                             it is a new type of therapy developed specifically for the
     Lidocaine is a local anesthetic with good absorption,     perineal region. The application is made in the form of
easy administration, and the patient herself may apply         a sanitary pad that extends from the labia major to the
it. Nevertheless, a study conducted in Texas, USA, with        anal region(25).
200 women divided into two groups, one receiving                    Despite hot compresses being one of the least used
placebo and the other, lidocaine, showed no significant        methods, scientists confirm that the application of heat
difference between the two groups. Therefore, lidocaine        interrupts pain and offers comfort to the patients. Some
was not effective in the relief of perineal pain(21).          studies showed that temperatures over 40 °C (104o F)
     Rectal analgesia includes the use of a local anesthetic   block the chemical messengers of the cells responsible
that can relieve pain of any intensity, caused by perineal     for alerting the body about pain, with an effect that may
trauma within the first 24 hours after the birth, and leads    last for up to one hour. Nonetheless, relief is temporary,
to less use of other types of analgesia during the first 48    but in spite of the restricted duration of the effect of
hours when used as a rectal suppository. There is no           heat, these discoveries may be useful for making the use
information available on the relief of pain with the use       of artifices such as hot water bottles more common in
of rectal suppository for three days after delivery(22).       the relief of pain(26).
     As to non-drug treatment, the use of ice packs was             The primary purposes in application of heat are to
the most common. Cold applications are therapeutically         reduce inflammation and alleviate the pain. The time of
prescribed in order to provoke vasoconstriction. This          application should be 20 minutes at most(23).
constriction reduces blood circulation in the area of               A study was conducted with the objective of assessing
application, affording relief of pain caused by decreasing     the effect of cold and hot treatment on the perineum
pressure on nerve endings. It is also used to decrease         of women who suffered lacerations and episiotomies.
hemorrhage, deter inflammation, prevent suppuration,           It comprised 90 women in three groups: 30 in the hot
and alleviate congestion(23).                                  water bottle group, 30 in the ice pack group, and 30 in
     With the objective of evaluating the effect of            the warm sitz-bath group. The duration of treatment
cryotherapy in relief of perineal region pain in               was established as 20 minutes. Perineal discomfort was
nulliparas, who had vaginal deliveries, a randomized and       evaluated before, immediately after, and at half an
controlled clinical trial was carried out, with a sample       hour, one hour, and two hours post-treatment. There
of 114 women, comparing the use of ice packs for 20            was no significant difference among the groups before,
minutes (Experimental) with the same time of use of a          immediately after, and after treatment(27).
water bottle (Placebo) and one group without treatment              Avoidance of perineal trauma is the best method
(Control) in a maternity located in the city of São Paulo.     for prevention of pain(7), as was observed in the present
The mean initial temperature of the perineum in all            study in which patients with episiotomies used more
three groups was 32.7 °C (90.86 °F). In the group with         non-steroidal anti-inflammatory drugs.
ice packs, the perineal temperature dropped to 12.6 °C              In an American study carried out with 23,244
(54.68 °F), in the water bottle group it increased to 30.9     women using multiple analysis logistic regression, it
°C (87.62 °F), and in the Control, to 34.2 °C (93.56 °F).      was determined that the main risk factors for third and
There was a significant improvement of pain in all three       fourth degree lacerations were: primiparity, newborn
groups, reducing from 4.6 to 3.3 in a 0 to 10 scale in the     weighing more than 4 kg, use of forceps, and median
Control Group, to 2.1 in the Placebo Group, and to 1.6         episiotomy(28-29).
in the Experimental Group. In the comparison of pain                In this study, we chose not to include forceps
among the groups, the Experimental Group had the               deliveries due to the small number of cases.
lowest mean relatively to the Control Group(24).                    In the present research study, nulliparas used more
     Another study was performed with the objective of         local anesthetic than primiparas and multiparas. The
assessing the effectiveness and comparing the use of           use of ice was also predominantly present among the
an ice pack and a local anti-inflammatory (Epifoam™),          nulliparas. As to weight of the newborn, there was a high
with a new randomized and controlled-type treatment,           percentage of non-steroidal anti-inflammatory drug use
in a maternity in the Northern region of England.              among women who gave birth to babies weighing more


einstein. 2009;7(2 Pt 1):194-200
Pharmacological and non pharmacological treatment for relief of perineal pain after vaginal delivery   199



than 3,500 g. The use of opioids was also greater for                                   7.	 Enkin M, Keirse MJNC, Neilson J, Crowther C, Duley L, Hodnett E, et al. A
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                                                                                            de Saúde da Mulher. Parto, aborto e puerpério: assistência humanizada à
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einstein. 2009;7(2 Pt 1):194-200

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1259 einsteinv7n2p194-200 ing

  • 1. Original Article Pharmacological and non pharmacological treatment for relief of perineal pain after vaginal delivery Tratamento farmacológico e não farmacológico no alívio da dor perineal pós-parto normal Joyce Hasegawa1, Lucila Coca Leventhal2 ABSTRACT Descritores: Dor; Períneo; Período pós-parto; Analgesia obstétrica; Objective: To identify the types of pharmacological and non- Parto pharmacological treatments used during hospitalization, in the relief of perineal pain after vaginal deliveries. Methods: Data were obtained from medical files of patients who had vaginal deliveries during 2007. INTRODUCTION Results: The mean age of mothers was 32.4 years, and 97.7% of Perineal trauma is a significant problem that affects them suffered perineal trauma. As to treatment for relief of perineal women worldwide who had vaginal deliveries, as it may pain after a vaginal delivery, 98.5% used drugs, the most frequent of cause pain and discomfort during the postpartum period. which were non-steroidal anti-inflammatory drugs, and 62.3% of them Several factors are responsible for perineal trauma, e.g., also used non-drug treatments, especially ice packs. Conclusion: It is important that healthcare professionals, who attend to new size of fetus, poor adaptation of the fetal presentation puerperas, know how to assess and treat perineal pain. Considering to the pubic symphysis, anomalous fetal positions, and the high rates of perineal trauma following vaginal deliveries, we need episiotomies(1-2). to offer patients treatment alternatives for perineal pain, based on Perineal loss of integrity may cause the woman scientific evidence. postpartum discomfort and may negatively influence psychological and physical function, especially pain(3). Keywords: Pain; Perineum; Postpartum period; Analgesia, obstetrical; In breastfeeding, pain inhibits the release of Delivery oxytocin, the hormone responsible for the ejection reflex (let-down reflex) and production of breast milk. Even when there is a normal production of RESUMO maternal milk, pain, fatigue and anxiety may impede Objetivo: Identificar os tipos de tratamentos farmacológicos e the delivery of milk to the newborn, increasing não farmacológicos utilizados no alívio da dor perineal após o parto normal, utilizados pela puérpera no período de internação. maternal anxiety even more and blocking the release Métodos: Os dados foram obtidos por meio dos prontuários of oxytocin(4). médicos de puérperas que tiveram parto normal no ano de 2007. It is important to point out that there is no reliable Resultados: A média de idade das puérperas foi de 32,4 anos e evidence that the routine use of the episiotomy has a 97,7% sofreram trauma perineal. Quanto ao tratamento para o alívio beneficial effect. Episiotomies provoke a greater loss da dor perineal, após o parto normal 98,5% utilizaram fármacos, of blood and increase the incidence of dyspareunia sendo o anti-inflamatório não esteroidal o mais frequente, e 62,3% and perineal pain after birth. They are indicated in utilizaram também o tratamento não farmacológico, o fármaco situations of fetal distress, large fetuses, prematurity, mais utilizado foi bolsa de gelo. Conclusão: É importante que os if the perineum has little elasticity, or there is vulvar profissionais que atendem à puérpera, saibam avaliar e tratar a dor perineal. Considerando as elevadas taxas de traumatismo perineal edema, and the threat of perineal laceration(5-6). após o parto normal ainda presentes em nossa população, precisa- Among the practices employed to avoid trauma, se oferecer às puérperas alternativas de tratamento para a dor we mention protection of the perineum and perineal perineal, com base em evidências científicas. massage during the final expulsion period(7). Final paper presented at Faculdade de Enfermagem do Hospital Israelita Albert Einstein – HIAE, São Paulo (SP), Brazil. Nurse from Faculdade de Enfermagem do Hospital Israelita Albert Einstein – HIAE, São Paulo (SP), Brasil. 1 Obstetric nurse; PhD in Obstetric Nursing from Escola de Enfermagem da Universidade de São Paulo – USP; Lecturer at the Child-maternal Nursing Department of Faculdade de Enfermagem of Hospital 2 Israelita Albert Einstein – HIAE, São Paulo (SP), Brazil. Corresponding author: Lucila Coca Leventhal – Avenida Professor Francisco Morato, 4.293 – Butantã – CEP 05521-200 – São Paulo (SP), Brasil – Tel.: 11 3746-1001 – e-mail: lucila0308@hotmail.com Received on Jan 17, 2009 – Accepted on Mar 12, 2009 einstein. 2009;7(2 Pt 1):194-200
  • 2. Pharmacological and non pharmacological treatment for relief of perineal pain after vaginal delivery 195 In an American research study carried out with physical therapy equipment, such as ultrasound and 1,573 women in the postpartum period, 67% of transcutaneous electrical nerve stimulation (TENS)(2). primiparas without episiotomies and 82.3% of those Ultrasound is a device that emits sound waves (16 to with episiotomies reported perineal pain two weeks 18 kHz) with a frequency of 3 MHz, which is not audible after birth(8). to the human ear. It requires continual assistance of the The physical factors associated with perineal pain operator during treatment and; therefore, has a high interfere in various activities of puerparas, such as cost relative to the physical therapist’s time. TENS is a walking, sitting, sleeping, self-care, caring for the low frequency device (varying from 1 to 250 HZ) that newborn, appetite, sexual dysfunction, which can lead sends electrical impulses through the skin. It possesses to maternal exhaustion and hinder the experience significant advantages such as low cost, few side effects, of maternity, in some cases even leading to marital and it is effective in decreasing pain and consumption problems(1). of analgesics(15-16). In a study conducted with puerperas who had vaginal deliveries in the city of São Paulo, the prevalence of pain was 96% higher during the first 24 hours, and perineal OBJECTIVE pain was the most frequently cited. The women referred To identify which types of drugs and non-drugs interference of pain in breastfeeding, sleeping, caring treatments are used during hospitalization in relief of for the baby, locomotion, and elimination (voiding and maternal perineal pain after a vaginal delivery. evacuating)(9). Despite the use of measures to prevent pain, there are several treatments for relief of perineal pain. METHODS Pharmacological and non-pharmacological methods This is a quantitative, descriptive, exploratory, and are used to treat this discomfort(2,10). retrospective study. This study was developed at According to the Dictionary of Drug Administration the maternity of Hospital Israelita Albert Einstein in Nursing, 2007/2008(11), pharmacological pain relief (HIAE). The maternity has 45 puerperium beds, four methods include non-steroidal anti-inflammatory drugs, delivery rooms, four prepartum/delivery/puerperium oral analgesics, local anesthetics and opioids. rooms, three prepartum rooms, and one screening Several factors should be considered in oral room. During the year 2007, at this hospital there analgesic preparations, such as intensity of pain, were 2,931 births; 2,283 (77.9%) of them were by probability of the medication causing constipation, caesarian section, 569 were normal (19.3%), and 83 gastric irritation, passage of the drug to maternal milk, by forceps (2.8%). and more serious adverse effects, such as prolonged From July 3rd to July 11th, 2008, the period during bleeding time(10). which the authors were available, data were collected According to these criteria, paracetamol and in medical files. All files of women who had vaginal ibuprofen are considered the safest ones for use during deliveries during the period of February 1st to April 29th, lactation, due to their short time of action and of reports 2007, were analyzed, totaling 130 patient files. of adverse effects on the newborn(12). For this study, an instrument that had been For non-pharmacological methods, we have observed developed by the authors themselves was used, in practice the use of ice packs, hot compresses, and with open-ended and closed questions, containing sitz-baths. three parts. The first part has identification data of Ice packs during the first 24 hours postpartum is a the women, such as age, level of schooling, marital traditional method used for the immediate symptomatic status, among others. The second part was composed relief of pain since it anesthetizes the perineum, but of data on gestation and delivery, such as type of this relief is generally short-lived, and there is no laceration and newborn birthweight. The third part evidence of any long-term benefit. After 24 hours, heat consisted of information on pharmacological and non- is recommended because it increases circulation to pharmacological methods of relieving pain used by the the region. Forms of heat used are hot compresses or puerpera during hospitalization. sitz-baths. It helps to reduce perineal edema, to avoid According to resolution 196/1996 of the National the formation of hematomas, to relieve discomfort, Council of Health, the project was approved by the to promote recovery of the wound by cleaning the Ethics in Research Committee of HIAE (Ethics in perineum and anus, and reduces inflammation(13-14). Research Committee approval protocol # 842), and Recently, new non-drug methods have been authorization was requested from this Committee to investigated for relief of pain. They are composed of not use the informed consent form. einstein. 2009;7(2 Pt 1):194-200
  • 3. 196 Hasegawa J, Leventhal LC Data were analyzed using descriptive statistics Table 2. Data on pregnancy and delivery and, presented in the form of tables using descriptive Data on pregnancy and delivery n % statistics. Gestational age 37 - 41 weeks 123 94.6 32 - 36 weeks 7 5.4 RESULTS Parity Nullipara 61 46.9 In July 2008, 130 patient medical files of puerperas who Primipara 52 40.0 had vaginal deliveries were identified during the period Multipara 17 13.1 from February to April 2007. Anesthesia Maternal age varied from 20 to 44 years, and most Yes 128 98.5 No 2 1.5 of them were between 20 and 34 years old (90/130; Perineal trauma 69.2%); the mean was 32.4, the median was 32, and the Yes 127 97.7 standard deviation, 3.9. Most of them had remunerated No 3 2.3 occupations (92.3%), had more than 12 years of NB sex schooling (98.4%), were married (93.8%), and white Female 67 51.5 (96.9%), as can be observed on Table 1. Male 63 48.5 Birth weight Table 1. Distribution of sociodemographic characteristics of puerperas studied < 2,500 g 5 3.9 2,500 – 3,500 g 103 79.2 Sociodemographic characteristics n % ≥ 3,500 g 22 16.9 Age group (years) NB: newborn. 20 – 34 years 90 69.2 ≥ 35 years 40 30.8 Occupation Table 3 shows that the most widely used drugs Remunerated job 120 92.3 were non-steroidal anti-inflammatory drugs (91.5%), Housewife 10 7.7 followed by oral analgesics (88.5%). Several patients Schooling had more than one type of drug prescribed. 8 - 11 years 1 0.8 12 and more years 128 98.4 No record 1 0.8 Table 3. Distribution of pharmacological groups treatment Marital status Pharmacological treatment n % Married 122 93.8 Non-steroidal anti-inflammatory drugs 119 91.5 Single 5 3.9 Oral analgesics 115 88.5 Separated 3 2.3 Local anesthetic 71 54.6 Skin color Opioids 21 16.1 White 126 96.9 Did not use 2 1.6 Yellow 4 3.1 According to gestation and delivery data presented As to the non-pharmacological treatment (Table 4) on Table 2, we note that all women of this study had used by 81 (62.3%) patients during hospitalization, ice prenatal accompaniment, with seven or more clinical packs were the most frequently used (61.5%), and they visits (100.0%); most mothers delivered at a gestational were prescribed up to six times a day for 20 minutes age of 37 to 41 weeks (94.6%). As to parity, 46.9% were each time. The second most common treatment used nulliparas, 40.0% primiparas, and 13.1% multiparas; was the warm sitz-baths (2.3%), and for some women 80.8% of them had not had abortions/miscarriages in more than one non-drug treatment was prescribed. their other gestations. Most women were anesthetized (98.5%). In 128 patients anesthetized, the most Table 4. Distribution of non-pharmacological groups treatment frequent type of anesthesia used was double anesthetic Non-pharmacological treatment n % block (79.7%), followed by rachianesthesia (10.9%) Ice packs 80 61.5 and epidural block (9.4%). It was also noted that 127 Warm sitz-bath 3 2.3 (97.7%) puerperas had perineal trauma. Hot compresses 1 0.8 Did not use 49 37.7 As to data on newborns, most were female (51.5%), with predominant weight between 2,500 to 3,500 g (79.2%), as presented on Table 2. Table 5 shows a high percentage of use of non- Of the 130 medical files selected, 98.5% women steroidal anti-inflammatory drugs, especially in women used pharmacological treatment and 62.3% used non- with newborns weighing more than 3,500 g. The use of pharmacological treatment. opioids was also greater (27.3%) among these patients. einstein. 2009;7(2 Pt 1):194-200
  • 4. Pharmacological and non pharmacological treatment for relief of perineal pain after vaginal delivery 197 Table 5. Distribution of women who used pharmacological and non-pharmacological Table 7. Distribution of women who used pharmacological and non-pharmacological treatment per newborn birth weight treatment per parity NB weight NB < 2,500 g NB 2,500 – 3,500 g NB > 3,500 g Parity Nulliparas Primiparas Multiparas Pharmacological Pharmacological treatment n (%) n (%) n (%) n (%) n (%) n (%) treatment Non-steroidal anti-inflammatory drugs 56 (91.8) 48 (92.3) 15 (88.2) Non-steroidal anti- 4 (80.0) 94 (91.3) 21 (95.4) Oral analgesics 54 (88.5) 45 (86.5) 16 (94.1) inflammatory drugs Local anesthetics 42 (68.8) 23 (44.2) 6 (35.3) Oral analgesics 4 (80.0) 90 (87.4) 21 (95.4) Opioids 8 (13.1) 11 (21.5) 2 (11.7) Local anesthetics 3 (60.0) 59 (57.3) 9 (40.9) Did not use 1 (1.6) 1 (1.9) - Opioids - 15 (14.5) 6 (27.3) Non-pharmacological treatment Did not use 1 (20.0) 1 (0.9) - Ice pack 42 (68.8) 31 (59.6) 7 (41.2) Non-pharmacological treatment Warm sitz-bath - 3 (5.7) - Ice pack 4 (80.0) 62 (47.7) 14 (63.6) Hot compresses 1 (1.6) - - Warm sitz-bath - 2 (1.94) 1 (4.5) Did not use 17 (27.8) 20 (38.5) 12 (70.6) Hot compresses - - 1 (4.5) Total 61 (100.0) 52 (100.0) 17 (100.0) Did not use 1 (20.0) 41 (31.5) 7 (31.8) Total 5 (100.0) 103 (100.0) 22 (100.0) medical files from which we collected data, there were NB: newborn nursing notes about perineal pain, but these annotations referred only to the presence or absence of the algesic As to the non-drug treatment, ice-packs were the most complaint. No record was found as to the application of frequently used in the three groups. a pain scale, report of improvement or worsening of the According to the type of trauma, as shown on pain and/or of any interference of pain in breastfeeding, Table 6, women with episiotomies were those who most in caring for the newborn, in sleeping, or in walking, used a non-steroidal anti-inflammatory drug (94.6%); among others. patients with lacerations usually used ice packs. In a study carried out in maternities in the city of Belo Horizonte, the prescription of analgesics was noted Table 6. Distribution of women who used pharmacological and non-pharmacological in 75.5%, and of non-steroidal anti-inflammatories in treatment per type of trauma 77.8%, in the immediate postpartum period, and more Type of trauma Episiotomy Laceration Intact perineum than one medication was prescribed simultaneously(17). Pharmacological treatment n (%) n (%) n (%) This shows the high rate of drugs prescribed for relief Non-steroidal anti-inflammatory 106 (94.6) 11 (73.3) 2 (66.7) drugs of pain. Oral analgesics 99 (88.4) 14 (93.3) 2 (66.7) In the present study, among pharmacological Local anesthetics 66 (59.2) 3 (20.0) 2 (66.7) treatments used, we noted that non-steroidal anti- Opioids 19 (17.0) 1 (6.7) 1 (33.3) inflammatories were the most frequently used drugs Did not use 1 (0.9) - 1 (33.3) in most cases. They make up the largest group of Non-pharmacological treatment analgesics, have moderate potency, and are widely used Ice pack 65 (58.8) 14 (93.3) 1 (33.3) in prevention and treatment of postoperative pain(18). Warm sitz-bath 1 (0.9) 2 (14.3) - The non-steroidal anti-inflammatory drugs are Hot compresses 1 (0.9) - - among the drugs most often used by patients. However, Did not use 46 (41.1) 1 (6.7) 2 (66.7) among the 27 non-steroidal anti-inflammatories Total 112 (100.0) 15 (100.0) 3 (100.0) marketed in Brazil, only 14 contained references to safety for use during breastfeeding(12,17). Regarding parity, as per Table 7, high indices were Oral analgesics were the second most frequently noted of the use of drugs in all three categories. However, used drug in this study. A bibliographic review with the nulliparas (68.8%) utilized more local anesthetics than objective of assessing analgesic efficacy and adverse did primiparas (44.2%) and multiparas (35.3%). The effects of a single dose of dipyrone for acute postoperative use of ice was also more frequently present among the pain, showed that dipyrone has efficacy similar to that of nulliparas. ibuprofen (400 mg) and other analgesics often used to treat moderate to intense postoperative pain. The most common adverse effects were somnolence, stomach DISCUSSION upsets, and nausea(19). In the present study, we noted that a large number The third most commonly used drug in this study of puerperas used pharmacological and non- was local anesthetic. A bibliographic review composed pharmacological treatments for the relief of pain during of 976 women, with the objective of evaluating the the postpartum period of hospitalization. In many effects of topically applied anesthetics in postpartum einstein. 2009;7(2 Pt 1):194-200
  • 5. 198 Hasegawa J, Leventhal LC perineal pain showed no significant differences in pain The study was composed of patients who underwent relief when the topic anesthetic was compared to the instrumentation during vaginal delivery. After 48 topical use of a placebo(1). hours postpartum, a statistically significant difference When pain passes the most intense level, codeine was found in reduction of edema, hematomas and derivatives are used, but they should be employed for pain. This was greater in the group that used the new short durations, since prolonged use predisposes toward treatment. The authors point out that it is likely that constipation, which is particularly important to avoid in the results of the new treatment were significant, since treatment of perineal pain(10,20). it is a new type of therapy developed specifically for the Lidocaine is a local anesthetic with good absorption, perineal region. The application is made in the form of easy administration, and the patient herself may apply a sanitary pad that extends from the labia major to the it. Nevertheless, a study conducted in Texas, USA, with anal region(25). 200 women divided into two groups, one receiving Despite hot compresses being one of the least used placebo and the other, lidocaine, showed no significant methods, scientists confirm that the application of heat difference between the two groups. Therefore, lidocaine interrupts pain and offers comfort to the patients. Some was not effective in the relief of perineal pain(21). studies showed that temperatures over 40 °C (104o F) Rectal analgesia includes the use of a local anesthetic block the chemical messengers of the cells responsible that can relieve pain of any intensity, caused by perineal for alerting the body about pain, with an effect that may trauma within the first 24 hours after the birth, and leads last for up to one hour. Nonetheless, relief is temporary, to less use of other types of analgesia during the first 48 but in spite of the restricted duration of the effect of hours when used as a rectal suppository. There is no heat, these discoveries may be useful for making the use information available on the relief of pain with the use of artifices such as hot water bottles more common in of rectal suppository for three days after delivery(22). the relief of pain(26). As to non-drug treatment, the use of ice packs was The primary purposes in application of heat are to the most common. Cold applications are therapeutically reduce inflammation and alleviate the pain. The time of prescribed in order to provoke vasoconstriction. This application should be 20 minutes at most(23). constriction reduces blood circulation in the area of A study was conducted with the objective of assessing application, affording relief of pain caused by decreasing the effect of cold and hot treatment on the perineum pressure on nerve endings. It is also used to decrease of women who suffered lacerations and episiotomies. hemorrhage, deter inflammation, prevent suppuration, It comprised 90 women in three groups: 30 in the hot and alleviate congestion(23). water bottle group, 30 in the ice pack group, and 30 in With the objective of evaluating the effect of the warm sitz-bath group. The duration of treatment cryotherapy in relief of perineal region pain in was established as 20 minutes. Perineal discomfort was nulliparas, who had vaginal deliveries, a randomized and evaluated before, immediately after, and at half an controlled clinical trial was carried out, with a sample hour, one hour, and two hours post-treatment. There of 114 women, comparing the use of ice packs for 20 was no significant difference among the groups before, minutes (Experimental) with the same time of use of a immediately after, and after treatment(27). water bottle (Placebo) and one group without treatment Avoidance of perineal trauma is the best method (Control) in a maternity located in the city of São Paulo. for prevention of pain(7), as was observed in the present The mean initial temperature of the perineum in all study in which patients with episiotomies used more three groups was 32.7 °C (90.86 °F). In the group with non-steroidal anti-inflammatory drugs. ice packs, the perineal temperature dropped to 12.6 °C In an American study carried out with 23,244 (54.68 °F), in the water bottle group it increased to 30.9 women using multiple analysis logistic regression, it °C (87.62 °F), and in the Control, to 34.2 °C (93.56 °F). was determined that the main risk factors for third and There was a significant improvement of pain in all three fourth degree lacerations were: primiparity, newborn groups, reducing from 4.6 to 3.3 in a 0 to 10 scale in the weighing more than 4 kg, use of forceps, and median Control Group, to 2.1 in the Placebo Group, and to 1.6 episiotomy(28-29). in the Experimental Group. In the comparison of pain In this study, we chose not to include forceps among the groups, the Experimental Group had the deliveries due to the small number of cases. lowest mean relatively to the Control Group(24). In the present research study, nulliparas used more Another study was performed with the objective of local anesthetic than primiparas and multiparas. The assessing the effectiveness and comparing the use of use of ice was also predominantly present among the an ice pack and a local anti-inflammatory (Epifoam™), nulliparas. As to weight of the newborn, there was a high with a new randomized and controlled-type treatment, percentage of non-steroidal anti-inflammatory drug use in a maternity in the Northern region of England. among women who gave birth to babies weighing more einstein. 2009;7(2 Pt 1):194-200
  • 6. Pharmacological and non pharmacological treatment for relief of perineal pain after vaginal delivery 199 than 3,500 g. The use of opioids was also greater for 7. Enkin M, Keirse MJNC, Neilson J, Crowther C, Duley L, Hodnett E, et al. A these patients. guide to effective care pregnancy and childbirth. Oxford: Oxford University Press; 2000. An adequate treatment of pain is not only a 8. Declercq E, Cunningham DK, Johnson C, Sakala C. Mother’s reports of pathophysiological issue, it is also an ethical and postpartum pain associated with vaginal and cesarean deliveries: results of a economic issue. The best control of pain avoids national survey. Birth. 2008;35(1):16-24. unnecessary suffering, which negatively interferes, for 9. Alexandre CW, Kimura AF, Tsunechiro MA, Oliveira SMJV. A interferência da example, in breastfeeding as the pain causes stress and dor nas atividades e necessidades da puérpera. Nursing. 2006;93(9):664-8. discomfort. Treatment affords greater satisfaction and 10. Enkin M, Keirse MJNC, Neilson J, Crowther C, Duley L, Hodnett E, et al. Dor e reduces the costs related to possible complications, desconforto perineais. In: Enkin M, Keirse MJNC, Neilson J, Crowther C, Duley which may in turn determine longer hospitalization L, Hodnett E, et al. Guia para atenção efetiva na gravidez e no parto. Rio de Janeiro: Guanabara Koogan; 2004. p. 243-7. periods(30-31). 11. Dicionário de Administração de Medicamentos na Enfermagem: 2007/2008. 5a ed. Rio de Janeiro: EPUB; 2006. CONCLUSION 12. Chaves RG, Lamounier JA, César CC, Corradi MAL, Mello RP de, Gontijo CM, et al. Amamentação e uso de antiinflamatórios não esteróides pela The most widely drugs used by the puerperant during nutriz: informações científicas versus conteúdo em bulas de medicamentos hospitalization were non-steroidal anti-inflammatory comercializadas no Brasil. 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