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TheThe
Carbohydrates:Carbohydrates:
Sugars, Starches,Sugars, Starches,
and Fibersand Fibers
Chapter 4Chapter 4
IntroductionIntroduction
• Brain
• Glucose
• Muscles
• Glucose
• Glycogen
• Fat
• Sources of carbohydrates
• “Fattening” – mistaken thinking
ChemistChemist’s View of’s View of
CarbohydratesCarbohydrates
• Carbohydrate family
• Atoms and chemical bonds
• Monosaccharides
• Chemical shorthand
• Glucose, fructose, galactose
• Disaccharides
• Maltose, sucrose, lactose
• Polysaccharides
Atoms and Their BondsAtoms and Their Bonds
ChemistChemist’s View of’s View of
CarbohydratesCarbohydrates
• Monosaccharides – three
• Same numbers and kinds of atoms
• Differing sweetness
• Glucose – blood sugar
• Part of every disaccharide
• Fructose
• Sweetest of the sugars
• Galactose
• Only in a few foods
Chemical Structure of Glucose
The Monosaccharides
ChemistChemist’s View of’s View of
CarbohydratesCarbohydrates
• Disaccharides
• Pairs of three monosaccharides
• Maltose – two glucose units
• Sucrose – glucose and fructose
• Lactose – galactose and glucose
• Condensation
• Links two monosaccharides together
• Hydrolysis
• Breaks a disaccharide in two
Condensation and HydrolysisCondensation and Hydrolysis
of a Disaccharideof a Disaccharide
ChemistChemist’s View of’s View of
CarbohydratesCarbohydrates
• Polysaccharides
• Glycogen
• Storage form of energy in the body
• Glucose units
• Starch
• Storage form of energy
in plants
• Glucose units
Glycogen and Starch
Compared
ChemistChemist’s View of’s View of
CarbohydratesCarbohydrates
• Polysaccharides
• Fibers
• Differ from starches
• Soluble fibers – benefits
• Insoluble fibers – benefits
• Functional fibers
• Resistant starches
• Phytic acid
The Bonds of Starch and
Cellulose Compared
Carbohydrate DigestionCarbohydrate Digestion
• Ultimate goal
• Glucose for absorption and use
• Hydrolysis via enzymes
• Mouth
• Amylase
• Stomach
• Stomach acid & protein-digesting enzymes
• Role of fiber
Carbohydrate DigestionCarbohydrate Digestion
• Small intestine
• Most carbohydrate digestion
• Pancreatic amylase
• Specific disaccharide enzymes
• Maltase
• Sucrase
• Lactase
• Large intestine
• Fibers
Carbohydrate AbsorptionCarbohydrate Absorption
• Active transport
• Glucose
• Galactose
• Facilitated diffusion
• Fructose
• Liver
• Conversion of fructose and galactose
Absorption ofAbsorption of
MonosaccharidesMonosaccharides
Lactose IntoleranceLactose Intolerance
• Lactase activity
• Highest immediately after birth
• Declines with age
• Symptoms of intolerance
• Causes of intolerance beyond age
• Prevalence
• Genetically determined
Lactose IntoleranceLactose Intolerance
• Dietary changes
• Manage dairy consumption rather than
restriction
• GI bacteria
• Fermented milk products
• Individualized diets
• Potential nutrient deficiencies
• Riboflavin, vitamin D, and calcium
Carbohydrate MetabolismCarbohydrate Metabolism
• Glucose is key player
• Storing glucose as glycogen
• Liver storage
• Condensation into glycogen
• Hydrolysis for release of glucose when
needed
• Muscle storage
• Selfishly hoards glycogen
Carbohydrate MetabolismCarbohydrate Metabolism
• Glucose for energy
• Fuels most of body’s cells
• Preferred source for brain, nerve cells, and
developing red blood cells
• Cellular breakdown of glucose
• Making glucose from protein
• Amino acid conversion
• Gluconeogenesis
Carbohydrate MetabolismCarbohydrate Metabolism
• Ketone bodies from fat fragments
• Inadequate supply of carbohydrates
• Fat metabolism shifts
• Ketone body formation – starvation
• Ketosis – acid-base balance
• Carbohydrate needs for protein sparing and
prevention of ketosis
• Using glucose to make fat
The Constancy of BloodThe Constancy of Blood
GlucoseGlucose
• Steady supply in blood stream
• Intestines – food
• Liver – glycogen
• Blood glucose homeostasis
• Insulin
• Glucose from blood into cells
• Glucagon & epinephrine
• Brings glucose out from storage
Maintaining Blood GlucoseMaintaining Blood Glucose
HomeostasisHomeostasis
The Constancy of BloodThe Constancy of Blood
GlucoseGlucose
• Balancing within the normal range
• Balanced meals at regular intervals
• Diabetes
• Insulin is either inadequate or ineffective
• Type 1 diabetes
• Type 2 diabetes
• Hypoglycemia
• Prevalence
The Constancy of BloodThe Constancy of Blood
GlucoseGlucose
• Glycemic response
• Speed of glucose absorption, level of blood
glucose, and return to normal glucose levels
• Low glycemic response
• Desired
• High glycemic response
• Glycemic index
• Benefits
• Utility
Health Effects of SugarsHealth Effects of Sugars
• Pleasure in moderate amounts
• Obesity and chronic disease
• Nutrient deficiencies
• Energy with few other nutrients
• Discretionary kcalories
• Honey
• More energy per spoonful
• Health benefits
Health Effects of SugarsHealth Effects of Sugars
• Dental caries
• Bacteria ferment sugars producing acid
• Food factors associated with tooth decay
• Time of food in mouth
• Sticky foods
• Frequency of sugar consumption
• Food choices
• Factors associated with tooth decay
Recommended Intakes ofRecommended Intakes of
SugarsSugars
• Dietary Guidelines
• Reduce the intake of kcalories from added
sugars
• DRI
• Added sugars
• No more than 25% of day’s total energy
• Impact on other food groups
• WHO and FAO recommendations
Alternative SweetenersAlternative Sweeteners
• Artificial sweeteners
• Non-nutritive sweeteners
• Large doses and adverse effects
• Stevia – an herbal product
• Generally recognized as safe (GRAS)
• Sugar alcohols
• Provide kcalories
• Benefits and side effects
Health Effects of Starch andHealth Effects of Starch and
FibersFibers
• Heart disease
• Whole grains
• Sources
• Soluble fibers
• Sources
• Improving heart disease risk factors
• Diet composition for reducing heart disease
risk
Health Effects of Starch andHealth Effects of Starch and
FibersFibers
• Diabetes
• High-fiber foods
• GI health
• High-fiber foods
• Ample fluids
• Weight management
• High-fiber foods and whole grains
• Feeling of fullness
Health Effects of Starch andHealth Effects of Starch and
FibersFibers
• Cancer
• Dietary fiber and colon cancer
• Fiber supplements
• Sources of dietary fiber
• Phytochemicals
• Preventing colon cancer
• Diluting, binding, and removing
• Bacterial fermentation
Health Effects of Starch andHealth Effects of Starch and
FibersFibers
• Excessive fiber
• Insufficient energy or nutrient needs
• Abdominal discomfort, gas, diarrhea
• GI obstruction
• Nutrient absorption
• Dietary goals
• Balance, moderation, variety
Characteristics, Sources, &Characteristics, Sources, &
Health Effects of FibersHealth Effects of Fibers
Recommended Intakes ofRecommended Intakes of
Starch & FibersStarch & Fibers
• DRI for carbohydrates
• 45 to 65% of energy requirement
• RDA for carbohydrates
• 130 grams per day
• Fiber
• DV: 11.5 grams per 1000-kcalories
• DRI: 14 grams per 1000-kcalories
• No UL
From Guidelines to GroceriesFrom Guidelines to Groceries
• Grains
• 1 ounce provides about 15g of carbohydrate
• “Three are key” message
• Vegetables
• Starch content
• Fruits
• Milk and milk products
• Protein foods
From Guidelines to GroceriesFrom Guidelines to Groceries
• Read food labels
• Total carbohydrate
• Starch, fibers, sugars
• Sugars
• Added and natural sugars
Bread Labels Compared
Carbs, kCalories,Carbs, kCalories,
andand
ControversiesControversies
Highlight 4Highlight 4
CarbohydratesCarbohydrates’ kCalorie’ kCalorie
ContributionsContributions
• Obesity and the link to carbohydrates
• Total daily energy intakes have increased
• Activity levels have declined
• Increase in body weight
• Epidemiological studies
• Inverse relationship between carbs & weight
• Weight loss
• kCalorie intake
Energy Nutrients over Time
Daily Energy Intake & Increases in
Adult Body Weight over Time
SugarsSugars’ Share in the Problem’ Share in the Problem
• Increase in consumption of added sugars
• High-fructose corn syrup
• Body fat stores
• Carbohydrate cravings
• Self-imposed labeling of foods
• Carbohydrate addictions
• Not physiological or pharmacological
SugarsSugars’ Share in the Problem’ Share in the Problem
• Appetite control
• Fructose and insulin
• Flaws in plausibility
• Food form – liquid or solid
• Simple to swallow
• Energy regulation
InsulinInsulin’s Response’s Response
• Surge of insulin levels
• Glycemic effect
• Factors impacting glycemic effect
• Glycemic index and body weight
• Insulin resistance
• Fructose
• Prediabetes and metabolic syndrome
• Body’s insulin response

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Chapter4

  • 2. IntroductionIntroduction • Brain • Glucose • Muscles • Glucose • Glycogen • Fat • Sources of carbohydrates • “Fattening” – mistaken thinking
  • 3. ChemistChemist’s View of’s View of CarbohydratesCarbohydrates • Carbohydrate family • Atoms and chemical bonds • Monosaccharides • Chemical shorthand • Glucose, fructose, galactose • Disaccharides • Maltose, sucrose, lactose • Polysaccharides
  • 4. Atoms and Their BondsAtoms and Their Bonds
  • 5. ChemistChemist’s View of’s View of CarbohydratesCarbohydrates • Monosaccharides – three • Same numbers and kinds of atoms • Differing sweetness • Glucose – blood sugar • Part of every disaccharide • Fructose • Sweetest of the sugars • Galactose • Only in a few foods
  • 8. ChemistChemist’s View of’s View of CarbohydratesCarbohydrates • Disaccharides • Pairs of three monosaccharides • Maltose – two glucose units • Sucrose – glucose and fructose • Lactose – galactose and glucose • Condensation • Links two monosaccharides together • Hydrolysis • Breaks a disaccharide in two
  • 9. Condensation and HydrolysisCondensation and Hydrolysis of a Disaccharideof a Disaccharide
  • 10. ChemistChemist’s View of’s View of CarbohydratesCarbohydrates • Polysaccharides • Glycogen • Storage form of energy in the body • Glucose units • Starch • Storage form of energy in plants • Glucose units
  • 12. ChemistChemist’s View of’s View of CarbohydratesCarbohydrates • Polysaccharides • Fibers • Differ from starches • Soluble fibers – benefits • Insoluble fibers – benefits • Functional fibers • Resistant starches • Phytic acid
  • 13. The Bonds of Starch and Cellulose Compared
  • 14. Carbohydrate DigestionCarbohydrate Digestion • Ultimate goal • Glucose for absorption and use • Hydrolysis via enzymes • Mouth • Amylase • Stomach • Stomach acid & protein-digesting enzymes • Role of fiber
  • 15. Carbohydrate DigestionCarbohydrate Digestion • Small intestine • Most carbohydrate digestion • Pancreatic amylase • Specific disaccharide enzymes • Maltase • Sucrase • Lactase • Large intestine • Fibers
  • 16. Carbohydrate AbsorptionCarbohydrate Absorption • Active transport • Glucose • Galactose • Facilitated diffusion • Fructose • Liver • Conversion of fructose and galactose
  • 18. Lactose IntoleranceLactose Intolerance • Lactase activity • Highest immediately after birth • Declines with age • Symptoms of intolerance • Causes of intolerance beyond age • Prevalence • Genetically determined
  • 19. Lactose IntoleranceLactose Intolerance • Dietary changes • Manage dairy consumption rather than restriction • GI bacteria • Fermented milk products • Individualized diets • Potential nutrient deficiencies • Riboflavin, vitamin D, and calcium
  • 20. Carbohydrate MetabolismCarbohydrate Metabolism • Glucose is key player • Storing glucose as glycogen • Liver storage • Condensation into glycogen • Hydrolysis for release of glucose when needed • Muscle storage • Selfishly hoards glycogen
  • 21. Carbohydrate MetabolismCarbohydrate Metabolism • Glucose for energy • Fuels most of body’s cells • Preferred source for brain, nerve cells, and developing red blood cells • Cellular breakdown of glucose • Making glucose from protein • Amino acid conversion • Gluconeogenesis
  • 22. Carbohydrate MetabolismCarbohydrate Metabolism • Ketone bodies from fat fragments • Inadequate supply of carbohydrates • Fat metabolism shifts • Ketone body formation – starvation • Ketosis – acid-base balance • Carbohydrate needs for protein sparing and prevention of ketosis • Using glucose to make fat
  • 23. The Constancy of BloodThe Constancy of Blood GlucoseGlucose • Steady supply in blood stream • Intestines – food • Liver – glycogen • Blood glucose homeostasis • Insulin • Glucose from blood into cells • Glucagon & epinephrine • Brings glucose out from storage
  • 24. Maintaining Blood GlucoseMaintaining Blood Glucose HomeostasisHomeostasis
  • 25. The Constancy of BloodThe Constancy of Blood GlucoseGlucose • Balancing within the normal range • Balanced meals at regular intervals • Diabetes • Insulin is either inadequate or ineffective • Type 1 diabetes • Type 2 diabetes • Hypoglycemia • Prevalence
  • 26. The Constancy of BloodThe Constancy of Blood GlucoseGlucose • Glycemic response • Speed of glucose absorption, level of blood glucose, and return to normal glucose levels • Low glycemic response • Desired • High glycemic response • Glycemic index • Benefits • Utility
  • 27. Health Effects of SugarsHealth Effects of Sugars • Pleasure in moderate amounts • Obesity and chronic disease • Nutrient deficiencies • Energy with few other nutrients • Discretionary kcalories • Honey • More energy per spoonful • Health benefits
  • 28. Health Effects of SugarsHealth Effects of Sugars • Dental caries • Bacteria ferment sugars producing acid • Food factors associated with tooth decay • Time of food in mouth • Sticky foods • Frequency of sugar consumption • Food choices • Factors associated with tooth decay
  • 29. Recommended Intakes ofRecommended Intakes of SugarsSugars • Dietary Guidelines • Reduce the intake of kcalories from added sugars • DRI • Added sugars • No more than 25% of day’s total energy • Impact on other food groups • WHO and FAO recommendations
  • 30. Alternative SweetenersAlternative Sweeteners • Artificial sweeteners • Non-nutritive sweeteners • Large doses and adverse effects • Stevia – an herbal product • Generally recognized as safe (GRAS) • Sugar alcohols • Provide kcalories • Benefits and side effects
  • 31. Health Effects of Starch andHealth Effects of Starch and FibersFibers • Heart disease • Whole grains • Sources • Soluble fibers • Sources • Improving heart disease risk factors • Diet composition for reducing heart disease risk
  • 32. Health Effects of Starch andHealth Effects of Starch and FibersFibers • Diabetes • High-fiber foods • GI health • High-fiber foods • Ample fluids • Weight management • High-fiber foods and whole grains • Feeling of fullness
  • 33. Health Effects of Starch andHealth Effects of Starch and FibersFibers • Cancer • Dietary fiber and colon cancer • Fiber supplements • Sources of dietary fiber • Phytochemicals • Preventing colon cancer • Diluting, binding, and removing • Bacterial fermentation
  • 34. Health Effects of Starch andHealth Effects of Starch and FibersFibers • Excessive fiber • Insufficient energy or nutrient needs • Abdominal discomfort, gas, diarrhea • GI obstruction • Nutrient absorption • Dietary goals • Balance, moderation, variety
  • 35. Characteristics, Sources, &Characteristics, Sources, & Health Effects of FibersHealth Effects of Fibers
  • 36. Recommended Intakes ofRecommended Intakes of Starch & FibersStarch & Fibers • DRI for carbohydrates • 45 to 65% of energy requirement • RDA for carbohydrates • 130 grams per day • Fiber • DV: 11.5 grams per 1000-kcalories • DRI: 14 grams per 1000-kcalories • No UL
  • 37. From Guidelines to GroceriesFrom Guidelines to Groceries • Grains • 1 ounce provides about 15g of carbohydrate • “Three are key” message • Vegetables • Starch content • Fruits • Milk and milk products • Protein foods
  • 38. From Guidelines to GroceriesFrom Guidelines to Groceries • Read food labels • Total carbohydrate • Starch, fibers, sugars • Sugars • Added and natural sugars
  • 41. CarbohydratesCarbohydrates’ kCalorie’ kCalorie ContributionsContributions • Obesity and the link to carbohydrates • Total daily energy intakes have increased • Activity levels have declined • Increase in body weight • Epidemiological studies • Inverse relationship between carbs & weight • Weight loss • kCalorie intake
  • 43. Daily Energy Intake & Increases in Adult Body Weight over Time
  • 44. SugarsSugars’ Share in the Problem’ Share in the Problem • Increase in consumption of added sugars • High-fructose corn syrup • Body fat stores • Carbohydrate cravings • Self-imposed labeling of foods • Carbohydrate addictions • Not physiological or pharmacological
  • 45. SugarsSugars’ Share in the Problem’ Share in the Problem • Appetite control • Fructose and insulin • Flaws in plausibility • Food form – liquid or solid • Simple to swallow • Energy regulation
  • 46. InsulinInsulin’s Response’s Response • Surge of insulin levels • Glycemic effect • Factors impacting glycemic effect • Glycemic index and body weight • Insulin resistance • Fructose • Prediabetes and metabolic syndrome • Body’s insulin response