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HawkPartners Perspective on
Payer Research
Discussion Document
August 2012




For more information contact:

Scott Wilkerson
Scott.wilkerson@hawkpartners.com
301 951-7046
The US health insurance landscape includes a mix of
    private commercial plans and government payers

                                   US Healthcare Payer Landscape
               8%
                      Other Gov’t                             Medicare                                         Age of
                      Programs                                                                                Covered
                                                                                                              Under Age 18
               6%
                                                  Medicaid                         Private Health             Age 18-65
                                                                                     Insurance
 Avg. Annual                                                                                                  Age 65+
  Spending
Growth, 2005- 4%                 Out of Pocket/                                                               Relative size of
    2010                          Uninsured*                                                                  circle
                                                                                                              represents total
                                                                                                              covered lives

               2%




               0%
                                      $250                  $500                  $750               $1,000
                                      Estimated Total Spending, US$B (2011)
        *Estimated covered lives based on number of uninsured
        Sources: US Census; Congressional Budget Office; CMS.gov “National Health Expenditures 2010-2020”
                                                                                                                        2
Both commercial health insurance and PBM markets are
consolidating, with large players increasingly dominant

Largest US Private Health Insurers                             US Pharmacy Benefit Managers
 Share of Total Premiums Written (2010)                               Share of Members (2010)




                                                                            32%        All Others

                   50%

                              All Others                                    4%         Argus Health Systems, Inc.
                                                                            5%         MedImpact Healthcare Systems
                                                                            6%         NovoLogix
                   3%         Highmark Inc.                                 8%
                   4%         Health Care Services                                     Health Information Designs, Inc.
                   5%         Aetna Inc.                                    9%         ICORE Healthcare, Inc.
                   6%         Humana Inc.
                                                                            10%        Medco Health Solutions, Inc.*
                   8%         Kaiser Permanente

                   10%        WellPoint                                     13%        CVS/Caremark Rx, Inc

                   16%        UnitedHealth Group                            13%        Express Scripts Inc.


                                                                      *Acquired by Express Scripts in April 2012
Sources: AM Mindpower Solutions; Pharmacy Benefit Manager Institute

                                                                                                                   3
Payer influence in the pharmaceutical marketplace has
risen dramatically
 As health care costs continue to rise, therapeutic categories become more
  crowded, and products become less differentiated, payers will gain even more
  influence
                               Which pharmaceutical stakeholder is the most
                                              influential?
           34%           33% 32%

                                                                                     26%


                                                   18%           17%                               2001-2006
     14%                                                               14%                         2007-2011
                                             10%


                                                                                            2%

      Payers            Specialists        Key Opinion             Others            General
                                             Leaders                               Practitioners

   Source: Monitor survey of 256 executives from large and mid-sized pharmaceutical companies

                                                                                                         4
As they gain influence, payers are looking for a more
strategic relationship with pharma companies




                                        Payers
Greater flexibility and
transparency with
                                    Private Insurers   More information about the
pricing/contracts                   Medicare           total cost of care vs.
                                    Medicaid           alternative therapies
                                    Other gov’t
                                     programs
                                    PBMs



Value-added programs to assist                          Providing information about
patients, pharmacists and clinicians                    their products and pipeline

       Payers are looking for pharma companies to partner with them to
             achieve better, more cost-effective patient outcomes
                                                                               5
The current environment has enhanced the need for market
research to understand payer needs and expectations

                    Potential Uses of Payer Market Research

        Clinical
                                Market Launch and
     Development/                                               LOE
                                     Growth
      Pre Launch

 • Market opportunity          • Value proposition      • LOE strategic
   assessment                    testing                  planning
 • Clinical trial              • Customer experience    • Generic competition
   design/endpoints              research                 impact assessment
 • Pricing and                 • New indications        • LOE messaging
   formulary tier                assessment/testing       testing
   placement                   • Specialty pharmacy
 • Packaging                     needs research
   /distribution strategy


                                                                           6
If done right, payer research provides significant insights
      Pharmaceutical Payer Research – Key Success Factors:

 1.
 1    Reaching the RIGHT respondents
       • Recruiting influential respondents from the leading national plans requires
         a strong network and database of MCO contacts, as well as utilizing senior
         recruiters with payer experience



 2.
 2    Mining maximum insights
       • Maximizing insights from payer research requires using skilled moderators
         with deep category knowledge, an understanding of payer dynamics, and
         appropriate sensitivity to payer time constraints and confidentiality issues



 3
 3.   Integrating the results
       • Significant value can be added by integrating payer insights with data from
         different areas, including physician and patient research, market
         forecasting, customer experience tracking, and competitive intelligence

                                                                                        7
HawkPartners has extensive experience with both private
payers and other large scale health organizations

 We have experience interviewing and surveying MCOs, PBMs, Specialty
  Pharmacies, and other payer organizations

    – We also have experience with other large scale health organizations, including key
       stakeholders from both Integrated Delivery Networks and large medical groups

 Working with our field partners, HawkPartners utilizes databases of specifically
  targeted Medical and Pharmacy Directors in managed care organizations

    – We recruit using phone, fax and email information, and conduct additional desk research as
       needed, especially to reach larger national plans and PBMs

    – Telephone recruitment is conducted by trained executive interviewers with prior experience
       recruiting these types of respondents

 HawkPartners and our field partners have recruited respondents from the
  largest US commercial plans and PBMs

    – We have also successfully recruited a wide range of payers in Europe and Asia Pacific




                                                                                                   8
HawkPartners has successfully completed payer
research in US, EU and other markets
 HawkPartners has completed projects with payers on such topics as customer
 experience, new product evaluation, prioritization of coverage considerations in a
 therapeutic area, product messaging development, as well as broader therapeutic
 category trends
                      Examples of HawkPartners Payer Research
  •   Oncology Payer Customer Experience Assessment (US)*
  •   HDL Market Opportunity Assessment (US & EU)
  •   Market Opportunity Assessment for New Product Formulation/Delivery (US)*
  •   Stroke Treatment Assessment (US &EU)
  •   Omega-3 Market Opportunity Assessment (US)
  •   Therapeutic Category Long-Term Opportunity Analysis (US & EU)*
  •   Chronic Pain Product Comparator Research (US)
  •   Ophthalmology Perceptions/Trends (US & EU)
  •   Diabetic Macular Edema Opportunity Assessment (Emerging Markets: Latin America, Eastern
      Europe, Africa/Middle East, Asia)
  •   Chronic Pain Product Profile Refresh (US)
  •   Impact of Packaging / Distribution Changes on Respiratory Medication (US)
  •   Bone Healing Development Strategy (US, EU, & Japan)
  •   Understanding Specialty Pharmacy Considerations for High-Risk Patient Groups (US)
        *see case study

                                                                                                9
Case Study: Measuring customer experience drivers
among payer account customers
 Challenge: Client seeks to establish a baseline measure of payer account customers’
  experiences to understand how well their needs are being addressed through partnerships
  with pharmaceutical companies.

         Most Important Pharma Company Attributes                                  HawkPartners’ Approach:
                      % Ranked in Top Three
       65%                   n=45
                                                                                      Utilized a quali-quant research
                                                         % Ranked #2 and 3            approach with pharmacy and
                                                         % Ranked #1                  medical directors from HMOs,
                    52%
                                                                                      PBMs and specialty pharmacy
       33%
                                                                                      to obtain a baseline read on key
                                  36%                                                 customer experience metrics as
                   37%                            30%                                 well as rich insights on CE
                                   14%                            23%
                                                                                      drivers.

       32%                                         25%            20%              Results: Client is using the
                                   22%                                                results to develop value-added
                   15%
                                                   5%              6%
                                                                                      programs to assist clinicians,
                                                                                      pharmacists and patients in
   Fair pricing   Resources      Listens to   Resources          Info for
                  to assist      needs of     to assist          health
                                                                                      partnership with payer
                  patients       managed      physicians/        economic             organizations.
                                 care         pharmacists        analysis

                              *Note: data has been disguised to protect confidentiality                         10
Case Study: Scenario planning for an existing medication
facing new category entrants
 Challenge: Pharmaceutical client recognizes the changing market landscape (new class
  of agents that is easier to use and the availability of a generic formulation of the market
  leader) and needs to proactively address to these issues.

             Perceived Benefits                      Questions / Drawbacks
                                                                                              HawkPartners’
             • Reduction in costs with                                                         Approach: Conducted
Pharmacy                                 • Cost
               lack of monitoring
Directors                                • All concerns expressed by physicians                qualitative research with
             • Easier to administer
                                         •   How will we know if it is absorbed?               specialist physicians,
                                         •   Dosage adjustments for BMI?
             • Ease of Admin
                                         •   Reversibility?
                                                                                               pharmacy directors and
Physicians   • Increased compliance
             • No need to monitor
                                         •   Metabolization?                                   other payers, exposing
                                         •   How to measure efficacy?
                                         •   Indications?                                      them to a product profile
                                         • Cost – will most likely be Tier 3 (with the         and eliciting their
Managed      • Reduction in costs with
                                           potential for one new agent on Tier 2)              feedback on their
                                                 • Will not impact coverage of current
Care           lack of monitoring                                                              perceived evolution of
                                                   branded meds as the expectation is that
Decision       requirements
                                                   all will already be Tier 3 when new
Makers       • Easier to administer
                                                   mechanism agents are introduced
                                                                                               the market and decision
                                         • All concerns expressed by physicians                making criteria.

  Results: Feedback confirmed that the agent will indeed face challenges but identified
    several potential strategies and tactics for the client to explore to retain share and
    deepen existing relationships with pharmacy and medical directors.

                                                                                                                     11
Case Study: Leveraging payer feedback to assess the
    market opportunity for a new product
    Challenge: To inform its development strategy for a new agent, a pharma client needed
       insights into the category’s evolving treatment paradigm, the role of both current and
       emerging treatment options, and unmet needs of payers.

                                                                                                     HawkPartners’ Approach:
             Category Coverage Decision Considerations                                                Conducted qualitative
    Efficacy            Safety              Cost             Guidelines       Administration          research with payers and
 Cost of entry      Cost of entry    Does drive           Given expense  Associated costs        KOLs. Augmented these
 Most important     Second in         coverage              of (Treatment       are key – so        findings with secondary
  but not really      importance but     • Especially if no   Type), Payers       (mechanism A)
  differentiating     not really           other advantage    want evidence       is preferred to     market research, including
  now                 differentiating  Total cost matters, will work in          (B)                 case studies of analogous
                      today                                   population         Frequency is
 Better efficacy                       includes admin-
                                                               • Or would         less important
                                                                                                      agents.
  alone may not      Superior safety related, e.g. office
                                        visits for                prefer agents   (but less often
  drive displace-     alone would
  ment of older       not drive         (Procedure)               which have      can help with      Results: Findings
                                                                  that data       better
  treatments          preferred        Rebates/contracts
                                                             Helps drive step    compliance)         revealed that payers will
                      status            can be vital in
                     But less safety   status decisions      decisions                               play a critical role in
                      is a big                                                                        shaping the category’s
                      problem
                                                                                                      treatment paradigm due to
                                                                                                      the agent’s expected high
                                                                                                      price and payers’ doubts
                                                                                                      regarding generics and
                                                                                                      other substitutes.
                                                                                                                           12

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HawkPartners Perspective on Payer Research

  • 1. HawkPartners Perspective on Payer Research Discussion Document August 2012 For more information contact: Scott Wilkerson Scott.wilkerson@hawkpartners.com 301 951-7046
  • 2. The US health insurance landscape includes a mix of private commercial plans and government payers US Healthcare Payer Landscape 8% Other Gov’t Medicare Age of Programs Covered Under Age 18 6% Medicaid Private Health Age 18-65 Insurance Avg. Annual Age 65+ Spending Growth, 2005- 4% Out of Pocket/ Relative size of 2010 Uninsured* circle represents total covered lives 2% 0% $250 $500 $750 $1,000 Estimated Total Spending, US$B (2011) *Estimated covered lives based on number of uninsured Sources: US Census; Congressional Budget Office; CMS.gov “National Health Expenditures 2010-2020” 2
  • 3. Both commercial health insurance and PBM markets are consolidating, with large players increasingly dominant Largest US Private Health Insurers US Pharmacy Benefit Managers Share of Total Premiums Written (2010) Share of Members (2010) 32% All Others 50% All Others 4% Argus Health Systems, Inc. 5% MedImpact Healthcare Systems 6% NovoLogix 3% Highmark Inc. 8% 4% Health Care Services Health Information Designs, Inc. 5% Aetna Inc. 9% ICORE Healthcare, Inc. 6% Humana Inc. 10% Medco Health Solutions, Inc.* 8% Kaiser Permanente 10% WellPoint 13% CVS/Caremark Rx, Inc 16% UnitedHealth Group 13% Express Scripts Inc. *Acquired by Express Scripts in April 2012 Sources: AM Mindpower Solutions; Pharmacy Benefit Manager Institute 3
  • 4. Payer influence in the pharmaceutical marketplace has risen dramatically  As health care costs continue to rise, therapeutic categories become more crowded, and products become less differentiated, payers will gain even more influence Which pharmaceutical stakeholder is the most influential? 34% 33% 32% 26% 18% 17% 2001-2006 14% 14% 2007-2011 10% 2% Payers Specialists Key Opinion Others General Leaders Practitioners Source: Monitor survey of 256 executives from large and mid-sized pharmaceutical companies 4
  • 5. As they gain influence, payers are looking for a more strategic relationship with pharma companies Payers Greater flexibility and transparency with  Private Insurers More information about the pricing/contracts  Medicare total cost of care vs.  Medicaid alternative therapies  Other gov’t programs  PBMs Value-added programs to assist Providing information about patients, pharmacists and clinicians their products and pipeline Payers are looking for pharma companies to partner with them to achieve better, more cost-effective patient outcomes 5
  • 6. The current environment has enhanced the need for market research to understand payer needs and expectations Potential Uses of Payer Market Research Clinical Market Launch and Development/ LOE Growth Pre Launch • Market opportunity • Value proposition • LOE strategic assessment testing planning • Clinical trial • Customer experience • Generic competition design/endpoints research impact assessment • Pricing and • New indications • LOE messaging formulary tier assessment/testing testing placement • Specialty pharmacy • Packaging needs research /distribution strategy 6
  • 7. If done right, payer research provides significant insights Pharmaceutical Payer Research – Key Success Factors: 1. 1 Reaching the RIGHT respondents • Recruiting influential respondents from the leading national plans requires a strong network and database of MCO contacts, as well as utilizing senior recruiters with payer experience 2. 2 Mining maximum insights • Maximizing insights from payer research requires using skilled moderators with deep category knowledge, an understanding of payer dynamics, and appropriate sensitivity to payer time constraints and confidentiality issues 3 3. Integrating the results • Significant value can be added by integrating payer insights with data from different areas, including physician and patient research, market forecasting, customer experience tracking, and competitive intelligence 7
  • 8. HawkPartners has extensive experience with both private payers and other large scale health organizations  We have experience interviewing and surveying MCOs, PBMs, Specialty Pharmacies, and other payer organizations – We also have experience with other large scale health organizations, including key stakeholders from both Integrated Delivery Networks and large medical groups  Working with our field partners, HawkPartners utilizes databases of specifically targeted Medical and Pharmacy Directors in managed care organizations – We recruit using phone, fax and email information, and conduct additional desk research as needed, especially to reach larger national plans and PBMs – Telephone recruitment is conducted by trained executive interviewers with prior experience recruiting these types of respondents  HawkPartners and our field partners have recruited respondents from the largest US commercial plans and PBMs – We have also successfully recruited a wide range of payers in Europe and Asia Pacific 8
  • 9. HawkPartners has successfully completed payer research in US, EU and other markets  HawkPartners has completed projects with payers on such topics as customer experience, new product evaluation, prioritization of coverage considerations in a therapeutic area, product messaging development, as well as broader therapeutic category trends Examples of HawkPartners Payer Research • Oncology Payer Customer Experience Assessment (US)* • HDL Market Opportunity Assessment (US & EU) • Market Opportunity Assessment for New Product Formulation/Delivery (US)* • Stroke Treatment Assessment (US &EU) • Omega-3 Market Opportunity Assessment (US) • Therapeutic Category Long-Term Opportunity Analysis (US & EU)* • Chronic Pain Product Comparator Research (US) • Ophthalmology Perceptions/Trends (US & EU) • Diabetic Macular Edema Opportunity Assessment (Emerging Markets: Latin America, Eastern Europe, Africa/Middle East, Asia) • Chronic Pain Product Profile Refresh (US) • Impact of Packaging / Distribution Changes on Respiratory Medication (US) • Bone Healing Development Strategy (US, EU, & Japan) • Understanding Specialty Pharmacy Considerations for High-Risk Patient Groups (US) *see case study 9
  • 10. Case Study: Measuring customer experience drivers among payer account customers  Challenge: Client seeks to establish a baseline measure of payer account customers’ experiences to understand how well their needs are being addressed through partnerships with pharmaceutical companies. Most Important Pharma Company Attributes  HawkPartners’ Approach: % Ranked in Top Three 65% n=45 Utilized a quali-quant research % Ranked #2 and 3 approach with pharmacy and % Ranked #1 medical directors from HMOs, 52% PBMs and specialty pharmacy 33% to obtain a baseline read on key 36% customer experience metrics as 37% 30% well as rich insights on CE 14% 23% drivers. 32% 25% 20%  Results: Client is using the 22% results to develop value-added 15% 5% 6% programs to assist clinicians, pharmacists and patients in Fair pricing Resources Listens to Resources Info for to assist needs of to assist health partnership with payer patients managed physicians/ economic organizations. care pharmacists analysis *Note: data has been disguised to protect confidentiality 10
  • 11. Case Study: Scenario planning for an existing medication facing new category entrants  Challenge: Pharmaceutical client recognizes the changing market landscape (new class of agents that is easier to use and the availability of a generic formulation of the market leader) and needs to proactively address to these issues. Perceived Benefits Questions / Drawbacks  HawkPartners’ • Reduction in costs with Approach: Conducted Pharmacy • Cost lack of monitoring Directors • All concerns expressed by physicians qualitative research with • Easier to administer • How will we know if it is absorbed? specialist physicians, • Dosage adjustments for BMI? • Ease of Admin • Reversibility? pharmacy directors and Physicians • Increased compliance • No need to monitor • Metabolization? other payers, exposing • How to measure efficacy? • Indications? them to a product profile • Cost – will most likely be Tier 3 (with the and eliciting their Managed • Reduction in costs with potential for one new agent on Tier 2) feedback on their • Will not impact coverage of current Care lack of monitoring perceived evolution of branded meds as the expectation is that Decision requirements all will already be Tier 3 when new Makers • Easier to administer mechanism agents are introduced the market and decision • All concerns expressed by physicians making criteria.  Results: Feedback confirmed that the agent will indeed face challenges but identified several potential strategies and tactics for the client to explore to retain share and deepen existing relationships with pharmacy and medical directors. 11
  • 12. Case Study: Leveraging payer feedback to assess the market opportunity for a new product  Challenge: To inform its development strategy for a new agent, a pharma client needed insights into the category’s evolving treatment paradigm, the role of both current and emerging treatment options, and unmet needs of payers.  HawkPartners’ Approach: Category Coverage Decision Considerations Conducted qualitative Efficacy Safety Cost Guidelines Administration research with payers and  Cost of entry  Cost of entry  Does drive  Given expense  Associated costs KOLs. Augmented these  Most important  Second in coverage of (Treatment are key – so findings with secondary but not really importance but • Especially if no Type), Payers (mechanism A) differentiating not really other advantage want evidence is preferred to market research, including now differentiating  Total cost matters, will work in (B) case studies of analogous today population  Frequency is  Better efficacy includes admin- • Or would less important agents. alone may not  Superior safety related, e.g. office visits for prefer agents (but less often drive displace- alone would ment of older not drive (Procedure) which have can help with  Results: Findings that data better treatments preferred  Rebates/contracts  Helps drive step compliance) revealed that payers will status can be vital in  But less safety status decisions decisions play a critical role in is a big shaping the category’s problem treatment paradigm due to the agent’s expected high price and payers’ doubts regarding generics and other substitutes. 12