1. Gigantism
Table 4
Kevin Knox, Kaley Miller,
Hailey Ray, Ashley Spaulding

2. W, J. (2009, Janu 21). Double vision. Retrieved from http://www.jeffreymd.com/2009/01/31/double-vision/
Symptoms
• Pretty big people (usually two
standard deviations above
normal height should be)
• Delayed puberty Vos, A., & Barnes, K.
(2011). Gigantism.
Retrieved from
• Double vision or difficulty http://misskay03.edu.gl
ogster.com/gigantism
/
with side vision
W, J. (2009, Janu
21). Double vision.
Retrieved from
http://www.jeffrey
md.com/2009/01/3
1/double-vision/

3. • Headaches
• Increased sweating
• Irregular periods (females)
• Large hands and feet with
large fingers and toes

4. • Release of breast milk
• Thickening of facial
features
• Weakness
• Bulging forehead

5. Causes
• ***Excess of growth
hormone ***(Acromegaly)
• Most commonly:
Noncancerous(adenoma)
tumor of the pituitary gland

6. • Carney complex

7. Possible solutions
• Medications that
reduce growth
hormone release
such as somatostain
analogs (growth
inhibiting
hormones)
• Dopamine agonoists
but they are the
least effective

8. Radiation
therapy can be
used to bring the
growth hormone
level back to
normal but it
take 5 to 10 years
to take full effect
and often effects
other pituitary
hormones

9. • Removal of tumor on pituitary through
endonasal surgery (through nose)

10. Exams and Tests
• CT or MRI scans
-CT uses x-rays
-MRI uses magnets to align
protons and take an MDM
vector (fancy picture)

11. Exams and Tests
• CT or MRI scans
-CT uses x-rays
-MRI uses magnets to align
protons and take an MDM
vector (fancy picture) CT
MRI

12. • Failure to suppress serum growth hormone
(GH) levels after an oral glucose challenge
(maximum 75g)
• Fancy way of saying they get you hopped up on
sugar and see if your body can suppress growth
hormone like a normal person would

13. Miscellaneous
• Female to male ratio
of 1:2 (twice as
common in males)
• Commonly occurs
with Acromegaly

14. Fact Sources
• Eckman, S. (2009, 11 23). Gigantism. Retrieved from
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002157/
• Goyal, S. (n.d.). Gigantism. Retrieved from
http://www.hxbenefit.com/gigantism-definition-symptoms-causes-
treatment-and-acromegaly.html
• gigantism 2012. Encyclopædia Britannica Online School Edition.
Retrieved 23 February 2012, from http://school.eb.com/eb/article-
9036788
• drug. ( 2012). In Encyclopædia Britannica. Retrieved from
http://school.eb.com/eb/article-10969
• Encyclopædia Britannica Online School Edition, s.v. "drug,"
accessed February 23, 2012, http://school.eb.com/eb/article-10969.
• drug 2012. Encyclopædia Britannica Online School Edition.
Retrieved 23 February 2012, from http://school.eb.com/eb/article-
10969
• acromegaly. ( 2012). In Encyclopædia Britannica. Retrieved from
http://school.eb.com/eb/article-9003588