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  • 1. GigantismTable 4Kevin Knox, Kaley Miller,Hailey Ray, Ashley Spaulding
  • 2. W, J. (2009, Janu 21). Double vision. Retrieved from http://www.jeffreymd.com/2009/01/31/double-vision/ Symptoms • Pretty big people (usually two standard deviations above normal height should be) • Delayed puberty Vos, A., & Barnes, K. (2011). Gigantism. Retrieved from • Double vision or difficulty http://misskay03.edu.gl ogster.com/gigantism / with side vision W, J. (2009, Janu 21). Double vision. Retrieved from http://www.jeffrey md.com/2009/01/3 1/double-vision/
  • 3. • Headaches• Increased sweating• Irregular periods (females)• Large hands and feet with large fingers and toes
  • 4. • Release of breast milk• Thickening of facial features• Weakness• Bulging forehead
  • 5. Causes• ***Excess of growth hormone ***(Acromegaly)• Most commonly: Noncancerous(adenoma) tumor of the pituitary gland
  • 6. • Carney complex
  • 7. Possible solutions• Medications that reduce growth hormone release such as somatostain analogs (growth inhibiting hormones)• Dopamine agonoists but they are the least effective
  • 8. Radiationtherapy can beused to bring thegrowth hormonelevel back tonormal but ittake 5 to 10 yearsto take full effectand often effectsother pituitaryhormones
  • 9. • Removal of tumor on pituitary through endonasal surgery (through nose)
  • 10. Exams and Tests• CT or MRI scans-CT uses x-rays-MRI uses magnets to align protons and take an MDM vector (fancy picture)
  • 11. Exams and Tests• CT or MRI scans-CT uses x-rays-MRI uses magnets to align protons and take an MDM vector (fancy picture) CT MRI
  • 12. • Failure to suppress serum growth hormone (GH) levels after an oral glucose challenge (maximum 75g)• Fancy way of saying they get you hopped up on sugar and see if your body can suppress growth hormone like a normal person would
  • 13. Miscellaneous• Female to male ratio of 1:2 (twice as common in males)• Commonly occurs with Acromegaly
  • 14. Fact Sources• Eckman, S. (2009, 11 23). Gigantism. Retrieved from http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002157/• Goyal, S. (n.d.). Gigantism. Retrieved from http://www.hxbenefit.com/gigantism-definition-symptoms-causes- treatment-and-acromegaly.html• gigantism 2012. Encyclopædia Britannica Online School Edition. Retrieved 23 February 2012, from http://school.eb.com/eb/article- 9036788• drug. ( 2012). In Encyclopædia Britannica. Retrieved from http://school.eb.com/eb/article-10969• Encyclopædia Britannica Online School Edition, s.v. "drug," accessed February 23, 2012, http://school.eb.com/eb/article-10969.• drug 2012. Encyclopædia Britannica Online School Edition. Retrieved 23 February 2012, from http://school.eb.com/eb/article- 10969• acromegaly. ( 2012). In Encyclopædia Britannica. Retrieved from http://school.eb.com/eb/article-9003588