General Genome Browser

1. GenomeBrowser

3. ,
Genome Browser
4 .

6. An Interview with Ewan Birney: Keynote Speaker at O’Relly’s Bioinformatics Technology Conference 2001/10

16.
•UCSC Human Genome Browser
•50,000 Hit/Day
•3,000 users/Day
•
•1,257 Hit/Day
•10 users/Day

17. Code Name : Acuvue
Objective: !

21. 1 3
2

23. Google Maps API Presentation
SNP Population
Reference Link

25.
•Part of Generic Model Organism Database Project
•Lightweight & portable
•Highly configurable
•Clean user interface
•Promotes data sharing

26.
•Find your Favorite Gene
•Find your Favorite Domain
•Find your Favorite Oligo
•Zoom - Low Magnification
•Zoom - Medium Magnification
•Zoom - High Magnification
•Zoom - Highest Magnification
•CustomTracks

27.
•End-user
•Turn tracks on and off, change order, change packing & labeling
attributes(stored in cookie)
•Data provider
•Change fonts, colors, text.
•Change overview-genetic map, contigs, coverage, karyotype.
•Define new tracks using simple config file.
•Tinker with track appearance to hearts content.

28.
Glyphs
DAS Adaptor
Remote
Source

29.
•Add your own tracks
•Add 3d party tracks
•Distributed annotation system support

33.
Glyphs
DAS Adaptor
UCSC
Genome
Browser

34. •Gbrowse on UCSC
•Gbrowse on EnsEMBL
•Gbrowse on both

36.
Gbrowse 2
Gbrowse 1 Gbrowse 3
My Gbrowse

37.
•BioPerl and Bio::Graphics Software Libraries
•Bio::DB::GFF Database
•GadFly Database
•Plug-ins

38.
seqid source type start end score strand phase attribute
Chr1 dbsnp snp 200 300 . + . ID=SNP:rs1234;alleles:G/T
Chr1 dbsnp snp 400 700 . + . ID=SNP:rs4321;alleles:G/T

39.
1
2 3 4 5
6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
A B C
(1,2,3,7,8,9,10,11) (1,4,14,15,16,17) (1,5,20)

42. •“One Click” install on Macintosh OSX
•“Three Click” install onWindows XP
•“Tippity-tappity-tap” install on Linux/Solaris/BSD
Unix

43. Genome Browser
10 %
90 %