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RISE program
Research proposal
 Francisco J Fuster
 While  using antiperspirant deodorant:
 -No smell
 -No sweat
 How does the antiperspirant work?
 -It clogs sweat ducts with aluminum
  compounds.
 Excessive   aluminum concentrations
  cause:
 -estrogen like effects that stimulate breast
  cancer cell growth.
 -cell membranes more fluid.
 Sweat Regulates:
 Body Temperature
 =can be affected by heat absorption.
    -so darker races sweat more due to
 light attraction by pigmentation.
 High   aluminum concentrations:
 -Make cell membranes more fluid. Like
  the disease Alzheimer’s which is why this
  is linked to the disease.
 Experiments with aluminum in blood:
 -prove that it causes fluidity in cell
  membrane
A safe consumption of aluminum:
 -<5 μg/kg/day.
 Most of it is removed by the kidneys.
 Any higher consumption can lead to
  many other symptons.
 Sweat Toxins:
 Dermcidin
  =Regulates the skin flora, functions as a
  natural antibiotic.
 Any substance absorbed needs to be
  released.
 -Ex. Nicotine from cigarettes.
 To find and avoid a probable cause of
  breast cancer.
 This may cause breast cancer because:
 -Toxins from sweat mutate lymphatic
  nodules from the nearby area.
• Do antiperspirant deodorants stimulate the
  growth of breast cancer cells?
• Do they cause harm to any other part of the
  human body?
• What is the quantity of aluminum being
  absorbed by the users?
Antiperspirant deodorant causes:
-Breast cancer
-trap toxins in the body
-Aluminum concentrations can further
 harm the human body.
-Is linked to Alzheimer’s disease.
 The more a person sweats while using
 the antiperspirant deodorant the more
 probability for additional health
 problems.
 Primarily:
  -Survey a population of 300 people.
    =Find out those who have used
 antiperspirant deodorant for more than a
 year.
This would take convincing those who use
 the antiperspirant deodorant to volunteer
 for an serum aluminum test which
 indicates the level of aluminum in blood.
 Volunteers  will be notified of their rights.
 At least 50 control and 50 experimental
  volunteers will be needed.
 Ask for history of cancer in family.
 Exercise is questioned.
 Race.
 Compare the levels of aluminum between
  control and experimental, the normal
  level of aluminum in blood, race and
  amount of exercise.
   www.nih.gov
   Jones J. Can rumors cause cancer? Journal of the National Cancer Institute
    2000; 92(18):1469–1471.

   Darbre PD. Underarm cosmetics and breast cancer. Journal of Applied
    Toxicology 2003; 23(2):89–95.

   Darbre PD. Aluminium, antiperspirants and breast cancer. Journal of
    Inorganic Biochemistry 2005; 99(9):1912–1919.

   Harvey PW, Everett DJ. Significance of the detection of esters of p-
    hydroxybenzoic acid (parabens) in human breast tumours. Journal of
    Applied Toxicology 2004; 24(1):1–4.
   Darbre PD, Aljarrah A, Miller WR, et al. Concentrations of parabens
    in human breast tumours. Journal of Applied Toxicology 2004;
    24(1):5–13.

   Mirick DK, Davis S, Thomas DB. Antiperspirant use and the risk of
    breast cancer. Journal of the National Cancer Institute 2002;
    94(20):1578–1580.

   McGrath KG. An earlier age of breast cancer diagnosis related to
    more frequent use of antiperspirants/deodorants and underarm
    shaving. European Journal of Cancer 2003; 12(6):479–485.

   Fakri S, Al-Azzawi A, Al-Tawil N. Antiperspirant use as a risk factor
    for breast cancer in Iraq. Eastern Mediterranean Health Journal
    2006; 12(3-4):478–482.
   Susan J. van Rensburg1, Machteld E. Carstens1, Felix C. V. Potocnik2,
    Abraham K. Aucamp3, Joshua J. F. Taljaard1 and Klaus R. Koch4
    Neurochemical Research a journal of Springer Netherlands 2005
    pgs 825-829
   Immune Mechanisms Against Extracellular Pathogens
    Nature Encyclopaedia of Life Sciences
   www.googlescholar.com

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Long term effects of antiperspirant deodorant1

  • 1. RISE program Research proposal Francisco J Fuster
  • 2.  While using antiperspirant deodorant: -No smell -No sweat  How does the antiperspirant work? -It clogs sweat ducts with aluminum compounds.
  • 3.  Excessive aluminum concentrations cause: -estrogen like effects that stimulate breast cancer cell growth. -cell membranes more fluid.
  • 4.  Sweat Regulates: Body Temperature =can be affected by heat absorption. -so darker races sweat more due to light attraction by pigmentation.
  • 5.  High aluminum concentrations: -Make cell membranes more fluid. Like the disease Alzheimer’s which is why this is linked to the disease.  Experiments with aluminum in blood: -prove that it causes fluidity in cell membrane
  • 6. A safe consumption of aluminum: -<5 μg/kg/day.  Most of it is removed by the kidneys.  Any higher consumption can lead to many other symptons.
  • 7.  Sweat Toxins: Dermcidin =Regulates the skin flora, functions as a natural antibiotic. Any substance absorbed needs to be released. -Ex. Nicotine from cigarettes.
  • 8.  To find and avoid a probable cause of breast cancer.  This may cause breast cancer because: -Toxins from sweat mutate lymphatic nodules from the nearby area.
  • 9. • Do antiperspirant deodorants stimulate the growth of breast cancer cells? • Do they cause harm to any other part of the human body? • What is the quantity of aluminum being absorbed by the users?
  • 10. Antiperspirant deodorant causes: -Breast cancer -trap toxins in the body -Aluminum concentrations can further harm the human body. -Is linked to Alzheimer’s disease.
  • 11.  The more a person sweats while using the antiperspirant deodorant the more probability for additional health problems.
  • 12.  Primarily: -Survey a population of 300 people. =Find out those who have used antiperspirant deodorant for more than a year. This would take convincing those who use the antiperspirant deodorant to volunteer for an serum aluminum test which indicates the level of aluminum in blood.
  • 13.  Volunteers will be notified of their rights.  At least 50 control and 50 experimental volunteers will be needed.  Ask for history of cancer in family.  Exercise is questioned.  Race.  Compare the levels of aluminum between control and experimental, the normal level of aluminum in blood, race and amount of exercise.
  • 14. www.nih.gov  Jones J. Can rumors cause cancer? Journal of the National Cancer Institute 2000; 92(18):1469–1471.  Darbre PD. Underarm cosmetics and breast cancer. Journal of Applied Toxicology 2003; 23(2):89–95.  Darbre PD. Aluminium, antiperspirants and breast cancer. Journal of Inorganic Biochemistry 2005; 99(9):1912–1919.  Harvey PW, Everett DJ. Significance of the detection of esters of p- hydroxybenzoic acid (parabens) in human breast tumours. Journal of Applied Toxicology 2004; 24(1):1–4.
  • 15. Darbre PD, Aljarrah A, Miller WR, et al. Concentrations of parabens in human breast tumours. Journal of Applied Toxicology 2004; 24(1):5–13.  Mirick DK, Davis S, Thomas DB. Antiperspirant use and the risk of breast cancer. Journal of the National Cancer Institute 2002; 94(20):1578–1580.  McGrath KG. An earlier age of breast cancer diagnosis related to more frequent use of antiperspirants/deodorants and underarm shaving. European Journal of Cancer 2003; 12(6):479–485.  Fakri S, Al-Azzawi A, Al-Tawil N. Antiperspirant use as a risk factor for breast cancer in Iraq. Eastern Mediterranean Health Journal 2006; 12(3-4):478–482.
  • 16. Susan J. van Rensburg1, Machteld E. Carstens1, Felix C. V. Potocnik2, Abraham K. Aucamp3, Joshua J. F. Taljaard1 and Klaus R. Koch4 Neurochemical Research a journal of Springer Netherlands 2005 pgs 825-829  Immune Mechanisms Against Extracellular Pathogens Nature Encyclopaedia of Life Sciences  www.googlescholar.com