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23rd Annual
Investment Conference & Luncheon
Opportunities In Challenging Markets

                 Presented by:

       Tim Moore, CFA®, Portfolio Manager
     Dennis Wassung, CFA®, Portfolio Manager
            Craig Goryl, CFA®, Analyst
Productivity & Efficiency Theme

           Timothy Moore, CFA®
             Portfolio Manager
       Cabot Money Management, Inc.
              216 Essex Street
        Salem, Massachusetts 01970
               800-888-6468
                eCabot.com
What is Productivity?
Productivity = Ratio of Output for each Input of Labor, Equipment and Capital/Cash

Efficiency = similar to Productivity but takes into account Effectiveness & Wastage (input focus)

You can be Productive but not Efficient if you consume a lot of resources to perform something quicker!



Measured By: Minutes Per Good Produced or Revenue per Employee or Revenue Per Total Comp

US Productivity Improvements = +2% Annually (Peak was „00-‟07 at +2.5% average annually)



Technology is #1 Driver of Productivity due to Innovation (Tech = ~25% of Cabot Equities exposure)
What is Productivity?




US derives 80% of its GDP from Services (Only 20% from Manufacturing compared to 36% 1980; World Bank)
What are the Benefits of
          Productivity/Efficiency?
 Higher Standard of Living (#1 benefit)
 Better Innovation (#2 benefit and underappreciated)
 Time & Cost Savings (from a reduction in work hours per
  project or lower overall cost per unit of achievement)
 Improved Education
 More Availability of Medicine
 Improved Social Programs
 Increased Real Incomes (more so in emerging markets)
Productivity Examples In Our Lives?
 Computer                     Tablets & Smartphones (every 2.5
 Internet                      cannibalize 1 desktop or laptop)
 Ecommerce                    Digital Wallet/Dollars
 Cell phones                  Electronic Medical Records
 Software Applications        Laser or Robotic Surgeries
 GPS Navigation Devices       MRI‟s
 Mobility                     Extended Battery Life
 Blogging & Text Messaging    Automobiles (not horse & carriage)
                               Air Travel
                               Alternative Energy (Solar & Wind)
Stock Specific Trends?
                  Datacenters Storage
                    Mobile Devices
            Enterprise Relationship Software
Global Sharing Capabilities of Data & Health Records, etc
Cloud Computing (Virtualization & Software As a Service)
               Cyber Security & Privacy
                      3D Printing
              Solar Panels or Wind Farms
The Downside of Productivity?
 Loss of Work hours & Jobs = Higher Unemployment because not as many
  workers needed to be hired to replace others (Outsourcing to Asia, etc)
 More Distractions (constant online news flow, too many emails, wasted
  time browsing internet, online video games, social media overindulgence)

 Easily Impacted by Cultures (countries or workplace), Location,
  Optimization, Resources Availability

 Cyber Security Issues & Identity Theft

 Need to address Bottlenecks, Workflow Inhibitors & Unmotivated Workers

 Not Easily or Objectively Measurable (3 different models/formulas to measure
  it with each having its own merit and validity)
Big Data & Mobile Revolution

         Dennis Wassung, CFA®
           Portfolio Manager
      Cabot Money Management, Inc.
             216 Essex Street
       Salem, Massachusetts 01970
              800-888-6468
               eCabot.com
The World Is Changing
Investment Opportunities
   Mobile Devices & Components
   Internet & Data Infrastructure
   Security – Network & Data
   Cloud Computing & Internet Software
Genomics and Personalized Medicine

              Craig Goryl, CFA®
                Equity Analyst
         Cabot Money Management, Inc.
                216 Essex Street
          Salem, Massachusetts 01970
                 800-888-6468
                  eCabot.com
Genomics – What is it?
Genomics – The study of organisms‟ hereditary
information. An organism‟s genome is its
complete set of DNA.

DNA – The chemical compound containing
instructions for developing and directing all the
body‟s activities. An identical copy is in each cell.

DNA Sequencing – The process of determining
the exact order of the chemical bases that make
up DNA, about 6.2 billion in total for a human.

The map of a person‟s DNA can tell us a lot about them, from their eye
color to their likelihood of developing cancer. Scientists understand parts of
the map, but most of it is still a mystery.
Genomics – Why is this Important?
Predictive Medicine – Based on my DNA, what are my chances of
developing a particular disease?

Diagnostics – What disease is this? Is it an aggressive form in need of
treatment, or is it better to wait?

Therapeutics – What causes this disease, and what drugs will cure it?

At the heart of genomics is the promise of personalized medicine. Because of
differences in DNA, treatments do not work the same for everyone. Someday
our current practice - prescribing the same drug for everyone who has a
given disease - will seem archaic. This is truly a revolution in healthcare.
Genomics – Key Trends
Sequencing – Getting faster and
cheaper every day

Bioinformatics – Managing and
analyzing huge data volume is a
problem

Commercialization – What knowledge is public domain? What is
proprietary?
Genomics – Key Trends
Privacy and Ethics
    Your DNA map is deeply personal; you wouldn‟t want to share
      it. Yet insurance companies can‟t operate with “information
      asymmetry.” They need to know what you know, or their
      business model falls apart.
    Infants and DNA sequencing – Where should we draw the line
      on unnatural selection or modifying DNA? Where will other
      cultures draw it?
    Is it helpful or harmful to know my chances of developing
      Alzheimer's? Who else should know? What is the accuracy of
      this prediction?
Genomics – Investment Opportunities
Sequencing equipment – This is an increasingly competitive
space with some parallels to personal computing. But sequencing
companies are positioned to expand into other products like
DNA analytics, informatics, storage, etc.

Diagnostics – the most advanced area in terms of
commercializing our knowledge of genetic information; a
beneficiary of cheap sequencing.

Ongoing research – We are always learning and searching for
new ways to help our clients capitalize on this important theme.
Market Research




Craig Goryl and Rob Lutts tour The Broad Institute
23rd Annual
Investment Conference & Luncheon

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Sl12 opportunities in challenging markets

  • 2. Opportunities In Challenging Markets Presented by: Tim Moore, CFA®, Portfolio Manager Dennis Wassung, CFA®, Portfolio Manager Craig Goryl, CFA®, Analyst
  • 3. Productivity & Efficiency Theme Timothy Moore, CFA® Portfolio Manager Cabot Money Management, Inc. 216 Essex Street Salem, Massachusetts 01970 800-888-6468 eCabot.com
  • 4. What is Productivity? Productivity = Ratio of Output for each Input of Labor, Equipment and Capital/Cash Efficiency = similar to Productivity but takes into account Effectiveness & Wastage (input focus) You can be Productive but not Efficient if you consume a lot of resources to perform something quicker! Measured By: Minutes Per Good Produced or Revenue per Employee or Revenue Per Total Comp US Productivity Improvements = +2% Annually (Peak was „00-‟07 at +2.5% average annually) Technology is #1 Driver of Productivity due to Innovation (Tech = ~25% of Cabot Equities exposure)
  • 5. What is Productivity? US derives 80% of its GDP from Services (Only 20% from Manufacturing compared to 36% 1980; World Bank)
  • 6. What are the Benefits of Productivity/Efficiency?  Higher Standard of Living (#1 benefit)  Better Innovation (#2 benefit and underappreciated)  Time & Cost Savings (from a reduction in work hours per project or lower overall cost per unit of achievement)  Improved Education  More Availability of Medicine  Improved Social Programs  Increased Real Incomes (more so in emerging markets)
  • 7. Productivity Examples In Our Lives?  Computer  Tablets & Smartphones (every 2.5  Internet cannibalize 1 desktop or laptop)  Ecommerce  Digital Wallet/Dollars  Cell phones  Electronic Medical Records  Software Applications  Laser or Robotic Surgeries  GPS Navigation Devices  MRI‟s  Mobility  Extended Battery Life  Blogging & Text Messaging  Automobiles (not horse & carriage)  Air Travel  Alternative Energy (Solar & Wind)
  • 8. Stock Specific Trends? Datacenters Storage Mobile Devices Enterprise Relationship Software Global Sharing Capabilities of Data & Health Records, etc Cloud Computing (Virtualization & Software As a Service) Cyber Security & Privacy 3D Printing Solar Panels or Wind Farms
  • 9. The Downside of Productivity?  Loss of Work hours & Jobs = Higher Unemployment because not as many workers needed to be hired to replace others (Outsourcing to Asia, etc)  More Distractions (constant online news flow, too many emails, wasted time browsing internet, online video games, social media overindulgence)  Easily Impacted by Cultures (countries or workplace), Location, Optimization, Resources Availability  Cyber Security Issues & Identity Theft  Need to address Bottlenecks, Workflow Inhibitors & Unmotivated Workers  Not Easily or Objectively Measurable (3 different models/formulas to measure it with each having its own merit and validity)
  • 10. Big Data & Mobile Revolution Dennis Wassung, CFA® Portfolio Manager Cabot Money Management, Inc. 216 Essex Street Salem, Massachusetts 01970 800-888-6468 eCabot.com
  • 11. The World Is Changing
  • 12.
  • 13.
  • 14. Investment Opportunities  Mobile Devices & Components  Internet & Data Infrastructure  Security – Network & Data  Cloud Computing & Internet Software
  • 15. Genomics and Personalized Medicine Craig Goryl, CFA® Equity Analyst Cabot Money Management, Inc. 216 Essex Street Salem, Massachusetts 01970 800-888-6468 eCabot.com
  • 16. Genomics – What is it? Genomics – The study of organisms‟ hereditary information. An organism‟s genome is its complete set of DNA. DNA – The chemical compound containing instructions for developing and directing all the body‟s activities. An identical copy is in each cell. DNA Sequencing – The process of determining the exact order of the chemical bases that make up DNA, about 6.2 billion in total for a human. The map of a person‟s DNA can tell us a lot about them, from their eye color to their likelihood of developing cancer. Scientists understand parts of the map, but most of it is still a mystery.
  • 17. Genomics – Why is this Important? Predictive Medicine – Based on my DNA, what are my chances of developing a particular disease? Diagnostics – What disease is this? Is it an aggressive form in need of treatment, or is it better to wait? Therapeutics – What causes this disease, and what drugs will cure it? At the heart of genomics is the promise of personalized medicine. Because of differences in DNA, treatments do not work the same for everyone. Someday our current practice - prescribing the same drug for everyone who has a given disease - will seem archaic. This is truly a revolution in healthcare.
  • 18. Genomics – Key Trends Sequencing – Getting faster and cheaper every day Bioinformatics – Managing and analyzing huge data volume is a problem Commercialization – What knowledge is public domain? What is proprietary?
  • 19. Genomics – Key Trends Privacy and Ethics  Your DNA map is deeply personal; you wouldn‟t want to share it. Yet insurance companies can‟t operate with “information asymmetry.” They need to know what you know, or their business model falls apart.  Infants and DNA sequencing – Where should we draw the line on unnatural selection or modifying DNA? Where will other cultures draw it?  Is it helpful or harmful to know my chances of developing Alzheimer's? Who else should know? What is the accuracy of this prediction?
  • 20. Genomics – Investment Opportunities Sequencing equipment – This is an increasingly competitive space with some parallels to personal computing. But sequencing companies are positioned to expand into other products like DNA analytics, informatics, storage, etc. Diagnostics – the most advanced area in terms of commercializing our knowledge of genetic information; a beneficiary of cheap sequencing. Ongoing research – We are always learning and searching for new ways to help our clients capitalize on this important theme.
  • 21. Market Research Craig Goryl and Rob Lutts tour The Broad Institute