CT of Pheochromocytoma: Findings in Symptomatic & Incidentally Discovered Tumors

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CT of Pheochromocytoma: Findings in Symptomatic & Incidentally Discovered Tumors Gaspar A. Motta-Ramirez, M.D. Erick M. Remer, M.D. Brian R. Herts, M.D. Amir Hamriahian, M.D. Inderbir S. Gill, MB. BCh. Emmanuel Bravo, M.D.

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Objective: The prognostic indictors of age-related poor outcomes in patients with acute myeloid leukemia (AML) are still controversial. The aim of this work was to provide comprehensive insights into the effect of different hemocytes and to investigate the association between age and clinical features in adult patients with AML. Study Design: A retrospective study was performed to determine the role of age in the therapeutic outcomes of AML. A total of 166 newly diagnosed adult patients’ data from January 2015 to November 2019 in Zhongshan Hospital of Xiamen University were collected and analyzed. Results: Older patients presented a poorer prognosis (p=0.001) with shorter overall survival, which is served as age-related outcomes. Binary logistic regression demonstrated that cytogenetic risk (OR=4.508, 95% CI 2.733–7.435), leukocyte (OR=7.410, 95% CI 1.139–5.910), and bone marrow blast cells (OR=3.261, 95% CI 1.075–5.615) were independent indictors for age-related prognosis. In addition, Kaplan-Meier curve also revealed that the above factors were associated with overall survival (all p values <0.001). Conclusion: Cytogenetic risk, leukocyte, and bone marrow blast cells are dominant factors which account for the age-related poor outcomes and shorter overall survival in AML. Keywords: acute myeloid leukemia, adult, cytogenetic risk, hemocyte, leukemia, overall survival

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Journal of the Formosan Medical Association (2011) 110, 695e700 Available online at www.sciencedirect.com journal homepage: www.jfma-online.com ORIGINAL ARTICLE A multivariable logistic regression equation to evaluate prostate cancer Jhih-Cheng Wang a, Steven K. Huan a, Jinn-Rung Kuo b, Chin-Li Lu c, Hung Lin a, Kun-Hung Shen a,* a Division of Urology, Departments of Surgery, Chi-Mei Medical Center, Tainan, Taiwan b Division of Neurosurgery, Department of Surgery, Chi-Mei Medical Center, Tainan, Taiwan c Department of Medical Research, Chi-Mei Medical Center, Tainan, Taiwan Received 29 January 2010; received in revised form 14 May 2010; accepted 9 August 2010 KEYWORDS Logistic regression; men’s health; probability; prostate cancer; risk factor; score * Corresponding author. Division of U Taiwan 710. E-mail address: [email protected] 0929-6646/$ - see front matter Copyr doi:10.1016/j.jfma.2011.09.005 Background/Purpose: A possible means of decreasing prostate cancer mortality is through improved early detection. We attempted to create an equation to predict the likelihood of having prostate cancer. Methods: Between January 2005 and May 2008, patients who received prostate biopsies were retrospective evaluated. The relationship between the possibility of prostate cancer and the following variables were evaluated: age; serum prostate specific antigen (PSA) level, prostate volume, numbers of prostatic biopsies, digital rectal examination (DRE) findings, and the presence of hypoechoic nodule under transrectal ultrasonography. Results: A multivariate regression model was created to predict the possibility of having prostate cancer, and a receiver-operating characteristic (ROC) curve was drawn based on the predictive scoring equation. Using a predictive equation, P Z 1/(1 � e�x), where X Z �4.88, þ 1.11 (if DRE positive), þ 0.75 (if hypoechoic nodule of prostate present), þ 1.27 (when 7 < PSA � 10), þ 2.02 (when 10 < PSA � 24), þ 2.28 (when 24 < PSA � 50), þ 3.93 (when 50 < PSA), þ 1.23 (when 65 < age � 75), þ 1.66 (when 75 < age), followed by ROC curve analysis, we showed that the sensitivity was 88.5% and specificity was 79.1% in predicting the possibility of prostate cancer. Conclusion: Clinicians can tailor each patient’s follow-up according to the nomogram based on this equation to increase the efficacy of evaluating for prostate cancer. Copyright ª 2011, Elsevier Taiwan LLC & Formosan Medical Association. All rights reserved. rology, Department of Surgery, Chi-Mei Medical Center, 901 Chung Hwa Road, Yung Kang City, Tainan, il.com (K.-H. Shen). ight ª 2011, Elsevier Taiwan LLC & Formosan Medical Association. All rights reserved. mailto:[email protected] http://dx.doi.org/10.1016/j.jfma.2011.09.005 www.sciencedirect.com/science/journal/09296646 http://www.jfma-online.com http://dx.doi.org/10.1016/j.jfma.2011.09.005 http://dx.doi.org/10.1016/j.jfma.2011.09.005 696 J.-C. Wang et al. Prostate cancer is the most common solid malignancy ...

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