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©2011 Quest Software, Inc. All rights reserved.
How Big Data Can
Revolutionize
Pharmaceutical R&D
1
©2011 Quest Software, Inc. All rights reserved.
After transforming customer-facing functions such as
sales and marketing, big data is extending its reach to
other parts of the enterprise. In research and
development, for example, big data and analytics are
being adopted across industries, including
pharmaceuticals.
As per McKinsey Global Institute estimation, “Applying
big-data strategies to better inform decision making
could generate up to $100 billion in value annually
across the US health-care system, by optimizing
innovation, improving the efficiency of research and
clinical trials, and building new tools for physicians,
consumers, insurers, and regulators to meet the promise
of more individualized approaches.”
2
©2011 Quest Software, Inc. All rights reserved.
In the Health-care & Pharmaceutical industries, data growth
is generated from several sources, including the R&D
process itself, retailers, patients, and caregivers.
Effectively utilizing these data will help pharmaceutical
companies better identify new potential drug candidates and
develop them into effective, approved and reimbursed
medicines more quickly.
Let’s imagine the vision, However many pharmaceutical
companies are wary about investing significantly in
improving big-data analytical capabilities, partly because
there are few examples of peers creating a lot of value from
it.
3
©2011 Quest Software, Inc. All rights reserved.
• Predictive modeling of biological processes and drugs
becomes significantly more sophisticated and widespread.
By leveraging the diversity of available molecular and
clinical data, predictive modeling could help identify new
potential-candidate molecules with a high probability of
being successfully developed into drugs that act on
biological targets safely and effectively.
4
©2011 Quest Software, Inc. All rights reserved.
• Patients are identified to enrol in clinical trials based on
more sources—for example, social media—than doctors’
visits. Furthermore, the criteria for including patients in a
trial could take significantly more factors (for instance,
genetic information) into account to target specific
populations, thereby enabling trials that are smaller,
shorter, less expensive, and more powerful.
5
©2011 Quest Software, Inc. All rights reserved.
• Trials are monitored in real time to rapidly identify
safety or operational signals requiring action to avoid
significant and potentially costly issues such as
adverse events and unnecessary delays.
6
©2011 Quest Software, Inc. All rights reserved.
• Instead of rigid data silos that are difficult to exploit,
data are captured electronically and flow easily between
functions. This easy flow is essential for powering the
real-time and predictive analytics that generate business
value.
7
©2011 Quest Software, Inc. All rights reserved.
CONCLUSION
The road ahead is indeed challenging, but the big-data
opportunity in pharmaceutical R&D is real, and the
rewards will be great for companies that succeed.
8
©2011 Quest Software, Inc. All rights reserved.
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How Big Data Can Revolutionize Pharmaceutical R&D

  • 1. 0 ©2011 Quest Software, Inc. All rights reserved. How Big Data Can Revolutionize Pharmaceutical R&D
  • 2. 1 ©2011 Quest Software, Inc. All rights reserved. After transforming customer-facing functions such as sales and marketing, big data is extending its reach to other parts of the enterprise. In research and development, for example, big data and analytics are being adopted across industries, including pharmaceuticals. As per McKinsey Global Institute estimation, “Applying big-data strategies to better inform decision making could generate up to $100 billion in value annually across the US health-care system, by optimizing innovation, improving the efficiency of research and clinical trials, and building new tools for physicians, consumers, insurers, and regulators to meet the promise of more individualized approaches.”
  • 3. 2 ©2011 Quest Software, Inc. All rights reserved. In the Health-care & Pharmaceutical industries, data growth is generated from several sources, including the R&D process itself, retailers, patients, and caregivers. Effectively utilizing these data will help pharmaceutical companies better identify new potential drug candidates and develop them into effective, approved and reimbursed medicines more quickly. Let’s imagine the vision, However many pharmaceutical companies are wary about investing significantly in improving big-data analytical capabilities, partly because there are few examples of peers creating a lot of value from it.
  • 4. 3 ©2011 Quest Software, Inc. All rights reserved. • Predictive modeling of biological processes and drugs becomes significantly more sophisticated and widespread. By leveraging the diversity of available molecular and clinical data, predictive modeling could help identify new potential-candidate molecules with a high probability of being successfully developed into drugs that act on biological targets safely and effectively.
  • 5. 4 ©2011 Quest Software, Inc. All rights reserved. • Patients are identified to enrol in clinical trials based on more sources—for example, social media—than doctors’ visits. Furthermore, the criteria for including patients in a trial could take significantly more factors (for instance, genetic information) into account to target specific populations, thereby enabling trials that are smaller, shorter, less expensive, and more powerful.
  • 6. 5 ©2011 Quest Software, Inc. All rights reserved. • Trials are monitored in real time to rapidly identify safety or operational signals requiring action to avoid significant and potentially costly issues such as adverse events and unnecessary delays.
  • 7. 6 ©2011 Quest Software, Inc. All rights reserved. • Instead of rigid data silos that are difficult to exploit, data are captured electronically and flow easily between functions. This easy flow is essential for powering the real-time and predictive analytics that generate business value.
  • 8. 7 ©2011 Quest Software, Inc. All rights reserved. CONCLUSION The road ahead is indeed challenging, but the big-data opportunity in pharmaceutical R&D is real, and the rewards will be great for companies that succeed.
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