3. Company Snapshot A Medicine Portfolio That Helps Prevent Disease and Promote Better Health at Every Stage of Life $71.3 Billion Combined Revenue in 2008 Sales in ~150 Countries Over 100,000 Colleagues Worldwide #1 Primary and #1 Specialty Care Company Globally Over 60 Products With Sales Greater Than $100 Million 16 Products With Sales Greater Than $1 Billion 78 Manufacturing Sites Worldwide Major R&D Operations and Partnerships in North America, Europe and Asia
4. Our Operating Model BioPharmaceutical Businesses Diversified Businesses Manufacturing Enabling Functions Customer Focused Primary Care Specialty Care Oncology Established Products Emerging Markets Animal Health Capsugel Consumer Healthcare Nutrition Nine Diverse Businesses Supported by Two Focused Research Organizations Business Units Including: Development, Medical, Sales & Marketing PharmaTherapeutics Research & Development BioTherapeutics Research & Development
5. Innovative Therapies in Key Areas of Unmet Medical Needs Neuroscience Oncology Pain/Inflammation Metabolic Disorders Vaccines Infectious Diseases Biotherapeutics Our Focus is on High Priority Disease Areas and Enhanced Biologics Capabilities
6. Research & Development – Highlights The Long Road to a New Medicine * 12-15 Year Process Discovery Exploratory Development Registration Full Development Idea Candidate Medicine Tested in 3-10,000 Patients (Phase III) Studies in 100-300 Patients (Phase II) Clinical Data Analysis New Medicine Formulations Developed Large Amounts of Candidate Medicine Synthesized Extensive Safety Studies Studies in Healthy Volunteers Phase I Project Team and Plans Early Safety Studies Candidate Screening Synthesis of Compounds
7. Research & Development – Highlights Our Pipeline (as of October 16, 2009) Pfizer Discovery Portfolio includes projects from BBC, IDU and PGRD as at Sept 2, 2009 Pfizer Clinical Portfolio (Phase 1 and beyond) includes publicly disclosed projects as of Sept 2, 2009 Wyeth Portfolio as of July 21, 2009 Pfizer Wyeth Phase 1 Phase 2 Phase 3 Reg Discovery Projects 42 31 25 3 199 14 16 7 4 240 259 360 Combined Portfolio Total = 600