Almac Solid State Chemistry Feb 10 Linked In

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Linda_Mccausland

An overview of Solid State Chemistry Services at Almac

Technology

Solid State Services at ALMAC Supporting the development of APIs from invention to launch February 2010

Overview ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Solid State Services ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

What makes us different? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Crystal Form ,[object Object],[object Object],1. Polymorphs and Salts http://pipeline.corante.com/archives/2009/08/25/ 2. Editorial, OPRD 15 Jan 2010

Effect of Polymorphism on Solubility Solubility of the fluoroquinolone (US Patent 5,985,893)

We consider the Whole Process Preferred Form Desired properties ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Micronise Issues: Form change De-lumping Particle size reduction Provides consistency ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Final Product Preferred Form Desired properties

Pre-formulation & Formulation Development Services ,[object Object],[object Object],[object Object],[object Object],[object Object]

Legal support (technical) ,[object Object],[object Object],[object Object]

Conclusion Almac can support every stage of the drug development process. We have solid state services to support differing research needs and budgets. Almac provides an integrated approach to drug substance and drug product.

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