Albemarle is one of the few firms in the world with the facilities and expertise to help you with product development at every stage, from contract research, process development and the pilot plant right through commercial-scale manufacturing.To us, “the yes formula” is all about the world-class facilities, exceptional people and proven expertise that combine to help make you successful. And we continue to demonstrate our commitment by bringing you additional custom services that make a real difference in high-stakes industries.What’s new with us? Plenty.

1. Additional Custom Services:
More Ways We Can Say Yes
Albemarle is one of the few firms in the world with the facilities and expertise
to help you with product development at every stage, from contract research,
CGMP AND FOOD-GR ADE
process development and the pilot plant right through commercial-scale HYDROGENATION
manufacturing. To us, “the yes formula” is all about the world-class facilities, Albemarle FCS features two facilities fully
capable of both cGMP and food-grade
exceptional people and proven expertise that combine to help make you hydrogenation:
successful. And we continue to demonstrate our commitment by bringing Orangeburg, South Carolina
you additional custom services that make a real difference in high-stakes
• Strong GMP culture – more than 20
industries. What’s new with us? Plenty. years manufacturing ibuprofen
• Additional experience with
injectable APIs
Cryogenics
• FDA registered: no Form 483s in more
Our Fine Chemistry Services (FCS) division recently added new equipment at the Orangeburg,
than 20 years
South Carolina, facility to meet growing customer demand for specialized reactions involving
extreme low temperatures. The equipment allows us to run cryogenic reactions to temperatures • FDA Food Facility Registration
as low as -90° C at a 2,700-gallon scale, and has already been used to carry out a synthetic step for • ISO 9001:2000 Certified since 2003
a drug intermediate at the new operational limit.
South Haven, Michigan
Targeted investments such as this large-scale cGMP cryogenic reaction system position us well
to develop and scale-up reactions to make APIs and late-stage pharmaceutical intermediates. • FDA Registered: Manufacturing APIs
since 1978
Allowing our experts to better serve diverse customer needs simultaneously helps ensure the
success of all their projects. • FDA Food Facility Registration
• Currently supports more than 25
Specialty Polymerization
FDA-registered products
FCS recently invested in facilities to serve Albemarle’s cGMP and specialized non-cGMP polymer
markets. Within the last year, we have: Our combined equipment includes:
• Added drying capacity and small-scale (kilo lab) capabilities at one facility for cGMP • Four (4) cGMP or food-grade
biomedical and pharmaceutical polymer applications; and hydrogenation units
• Upgraded custom manufacturing capabilities and expertise at other facilities to produce new • 2,000- to 2,700-gallon capacity
and unique polymers for electronics, coatings, specialized polyolefin and other applications. • Stainless steel and Hastelloy®
Albemarle has developed, manufactured and improved polymer catalysts and catalyst systems alloy construction
on custom, confidential and commercial bases for more than 40 years. With flexible and scalable • Up to 150 psig hydrogen
custom manufacturing assets at several U.S. plants, we have the expertise and facilities to meet
a wide range of polymer manufacturing needs.

2. South Haven cGMP Hydrogenation Examples
Benzylic Hydrogenolysis Reduction of a Nitroarene
Orangeburg cGMP Hydrogenation Examples
Alkene Hydrogenation: Orangeburg Ibuprofen Process Reduction of a Nitropyridine
Food Grade Hydrogen Examples
Reductive Amination: South Haven Product Alkene Hydrogenation: Orangeburg Product
Find out how we say yes to hundreds of fine chemistry projects annually.
Albemarle is experienced and equipped to provide high-quality products and services to customers worldwide.
To learn more about our latest custom services — or find out how our extensive know-how can meet your
unique needs — contact your Albemarle Representative today.
AMERICAS E U R O P E , M I D D L E E A S T, A F R I C A
Fine Chemistry Services EMA Fine Chemistry Services
Tel: +1 225 388 7402 Tel: +32 10 48 1711
ALBSales@albemarle.com EMASales@albemarle.com
www.albemarle.com
The information presented herein is believed to be accurate and reliable, but is presented without guarantee or responsibility on the part of Albemarle Corporation. It is the responsibility
of the user to comply with all applicable laws and regulations and to provide for a safe workplace. The user should consider any information contained herein, including information about
any health or safety hazards, only as a guide, and should take those precautions that are necessary or prudent to instruct employees and to develop work practice procedures in order to
promote a safe work environment. Further, nothing contained herein shall be taken as an inducement or recommendation to manufacture or use any of the herein described materials or
processes in violation of existing or future patents.
FCS-0004 (01/11)