Hyperoxaluria is characterized by increased urinary excretion of oxalate. It can be caused by genetic mutations that result in oxalate overproduction (primary hyperoxaluria) or enteric hyperoxaluria, which can occur due to malabsorptive states and/or less well-understood genetic causes. Additionally, there are dietary factors that can impact urinary oxalate excretion. Primary and secondary hyperoxaluria are two distinct clinical expressions of hyperoxaluria.
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2. Primary Hyperoxaluria DelveInsight
Hyperoxaluria is characterized by increased urinary excretion of oxalate. It can be
caused by genetic mutations that result in oxalate overproduction (primary
hyperoxaluria) or enteric hyperoxaluria, which can occur due to malabsorptive states
and/or less well-understood genetic causes. Additionally, there are dietary factors
that can impact urinary oxalate excretion. Primary and secondary hyperoxaluria are
two distinct clinical expressions of hyperoxaluria.
Primary Hyperoxaluria Epidemiology Segmentation in the 7MM
Prevalent Cases of Primary Hyperoxaluria
Diagnosed Prevalent Cases of Primary Hyperoxaluria
Gender-specific Diagnosed Prevalent Cases of PrimaryHyperoxaluria
Age-specific Diagnosed Prevalent Cases of Primary Hyperoxaluria
Type-specific DiagnosedPrevalent Cases of Primary Hyperoxaluria
Primary Hyperoxaluria Epidemiological Insights Observed in the 7MM (2021)
The total prevalent population of Primary Hyperoxaluria in the 7MM was
estimated to be 11.9K cases.
The total prevalent population of Primary Hyperoxaluria in the US was found
to be 8.7K cases.
The total diagnosed prevalent population of Primary Hyperoxaluria in the US
was almost 2.3K cases.
The total diagnosed prevalent population of Primary Hyperoxaluria in the UK
was observed to be 202 cases.
The total diagnosed prevalent population of Primary Hyperoxaluria in
Germany was found to be 180 cases.
The total diagnosed prevalent population of Primary Hyperoxaluria in Japan
was estimated to be 80 cases.
Primary Hyperoxaluria Market Insight
The market size of Primary Hyperoxaluria in the 7MM was found to be
approximately USD 81 million in the year 2021.
3. Primary Hyperoxaluria DelveInsight
Primary Hyperoxaluria Market Drivers
Current and Future Changes in the Paradigm of Therapies
Entry of Approved Therapy
Future Potentials of Emerging Treatment
Increasing Prevalence
Global Exposure
Primary Hyperoxaluria Market Barriers
Lack of Available Long-term Data
Lack of Robust Pipeline
Delayed Diagnosis
Challenges in terms of management
Primary Hyperoxaluria Emerging Drugs
The emerging drugs in the Primary Hyperoxaluria market are
Oxabact (OC5-DB-02)
Nedosiran (DCR-PHXC)
Reloxaliase (ALLN-177)
Stiripentol (Diacomit), and several others
Primary Hyperoxaluria Key Players
The key players working in the Primary Hyperoxaluria market are
OxThera
Dicerna Pharmaceuticals, Inc
Allena Pharmaceuticals
Biocodex, and many others