2. INTRODUCTION
• Cancer is the uncontrolled growth of cells that do not
function properly.
• As these cells increase in number, they tend to crowd out
normal healthy cells or develop into a solid mass,
causing signs and symptoms of disease to appear.
• Typically, the cancer develops at a primary site, but it
may metastasize or spread to other areas of the body.
3. TYPE OF PEDIATRIC CANCER
Leukemia
, Wilms
tumor,
Rhabdomyos
arcoma,
Osteosarcoma,
Ewing sarcoma
Retinoblastoma
,
Neuroblastoma
,
Brain
tumors,
lymphomas,
4. Leukemia
• The most common pediatric leukemia is acute
Lymphoblastic leukemia (ALL), also known as acute
lymphocytic leukemia or acute lymphoid leukemia.
• ALL is most common in children 2 and 3 years of age.
• The second most common pediatric leukemia is acute
myeloid leukemia (AML)
• The survival rate of children with AML is less favorable
than that of children with ALL
6. Lymphoma
• The third most common type of cancer in children is
lymphoma,
• These malignancies arise in the lymphoid cells and have
their own biologic subtypes.
7. Ewing Sarcoma
• Ewing sarcoma is the second most common type of bone
malignancy in children and adolescents.
• It is thought that Ewing sarcoma originates from neural crest
cells;
• Ewing sarcomas are considered to be a tumor primarily of the
bone or soft tissue.
• Common sites for Ewing sarcoma are the vertebral column,
pelvis, rib, and long bones such as the femur, tibia, and fibula
• Approximately 56% of patients who develop Ewing sarcoma
are 10 to 20 years old.
8. Wilms Tumor
• Wilms tumor, also called nephroblastoma, is the most
common malignancy of the kidney in children.
• Children younger than 6 years of age are more likely to
have Wilms tumor than are older children;
• it is commonly diagnosed between 3 and 4 years of age.
• The primary signs and symptoms of Wilms tumor are
abdominal swelling or mass, fever, anaemia
&hypertension.