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Journal of Clinical and
Medical Images
ISSN: 2640-9615
Clinical Images
Tumoral Calcinosis as a Bone Pseudotumor
Babak A1*
, Tarhani F2
and Sabzyan K3
1
Assistant Professor of Pediatric Hematology-Oncology, Lorestan University of Medical Sciences, Khoramabad
2
Assistant Professor of Pediatric, Lorestan University of Medical Sciences, Khoramabad
3
Assistant Professor of Pediatric Nephrology, Lorestan University of Medical Sciences, Khoramabad
Volume 3 Issue 1- 2020
Received Date: 19 Dec 2019
Accepted Date: 31 Dec 2019
Published Date: 04 Jan 2020
*Corresponding Author (s): : Babak Abdolkarimi, Assistant Professor of Pediatric Hematol-
ogy-Oncology, ShahiMadani Hospital, Lorestan University of Medical Sciences, Khoramabad,
Iran, Tel: 09183605274, E-mail: b.abdolkarimi@yahoo.com
clinandmedimages.com
Citation: Babak A, Assistant Professor of Pediatric Hematology-Oncology, Lorestan University of Medical
Sciences, Khoramabad. Journal of Clinical and Medical Images. 2020; V3(1): 1-2.
1. Clinical Image
The radiographic findings of tumoral calcinosis in a 2- years old girl with limping include periarticular
ovaloid calcifications or calcified cysts with calcium layering in the dependent portion giving the
appearance of sedimentation sign.
Tumoral calcinosis is a rare condition in which there is calcium deposition in the soft tissue in
periarticular location around joints. The accumulations are outside the joint capsule. They are
frequently (0.5–3%) seen in patients undergoing renal dialysis. This radiologic diagnosis mimics
tumoral features such as osteosaromma. Infact this is a pseudotumor.
Combining the laboratory tests like serum chemistry levels particularly markers for assessing the
phosphate metabolism, parathyroid, albumin and protein, 24-h urine sample, is essential part of the
work up. Also collagen vascular disease should be worked up. The diagnosis in this patient was also
confirmed by genetics using whole exome sequencing (WES) and found to have GALNT3 mutation.
These lesions are usually painless but may result in deformity or restricted motion of the adjacent joint.
(Figure 1 and 2).
Figure1:There are large unilateral ovaloid soft-tissue multilocular
calcifications seen around the hips with internal cystic and
sedimentation levels. The underlying bony structures are
unremarkable before treatment.
Figure2: Normal X-ray after mass resection

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Tumoral Calcinosis as a Bone Pseudotumor

  • 1. Journal of Clinical and Medical Images ISSN: 2640-9615 Clinical Images Tumoral Calcinosis as a Bone Pseudotumor Babak A1* , Tarhani F2 and Sabzyan K3 1 Assistant Professor of Pediatric Hematology-Oncology, Lorestan University of Medical Sciences, Khoramabad 2 Assistant Professor of Pediatric, Lorestan University of Medical Sciences, Khoramabad 3 Assistant Professor of Pediatric Nephrology, Lorestan University of Medical Sciences, Khoramabad Volume 3 Issue 1- 2020 Received Date: 19 Dec 2019 Accepted Date: 31 Dec 2019 Published Date: 04 Jan 2020 *Corresponding Author (s): : Babak Abdolkarimi, Assistant Professor of Pediatric Hematol- ogy-Oncology, ShahiMadani Hospital, Lorestan University of Medical Sciences, Khoramabad, Iran, Tel: 09183605274, E-mail: b.abdolkarimi@yahoo.com clinandmedimages.com Citation: Babak A, Assistant Professor of Pediatric Hematology-Oncology, Lorestan University of Medical Sciences, Khoramabad. Journal of Clinical and Medical Images. 2020; V3(1): 1-2. 1. Clinical Image The radiographic findings of tumoral calcinosis in a 2- years old girl with limping include periarticular ovaloid calcifications or calcified cysts with calcium layering in the dependent portion giving the appearance of sedimentation sign. Tumoral calcinosis is a rare condition in which there is calcium deposition in the soft tissue in periarticular location around joints. The accumulations are outside the joint capsule. They are frequently (0.5–3%) seen in patients undergoing renal dialysis. This radiologic diagnosis mimics tumoral features such as osteosaromma. Infact this is a pseudotumor. Combining the laboratory tests like serum chemistry levels particularly markers for assessing the phosphate metabolism, parathyroid, albumin and protein, 24-h urine sample, is essential part of the work up. Also collagen vascular disease should be worked up. The diagnosis in this patient was also confirmed by genetics using whole exome sequencing (WES) and found to have GALNT3 mutation. These lesions are usually painless but may result in deformity or restricted motion of the adjacent joint. (Figure 1 and 2). Figure1:There are large unilateral ovaloid soft-tissue multilocular calcifications seen around the hips with internal cystic and sedimentation levels. The underlying bony structures are unremarkable before treatment. Figure2: Normal X-ray after mass resection