More Related Content More from ssuser53e121 (9) Peripheral_Neuropathy.ppt9. 12/13/2022
CBC, ESR, FBS, TSH, B12, LFT, Hep screen,
SPEP, UPEP, Toxicology screen
Autoantibodies:
Anti-GM1
Anti-MAG
Paraneoplastic: Anti-Hu
NCS/EMG
CSF
Genetic
Nerve biopsy
Laboratory
23. 12/13/2022
(1) Median Neuropathy
Most common
CTS: Most common
Women 3:1, DM, rheumatoid arthritis,
hypothyroidism, pregnancy
Nocturnal numbness or pain
Dropping things: APB
+ Tinel’s, phalen’s signs
NCS/EMG
Splinting vs. surgical decompression
28. 12/13/2022
(4) Common Peroneal Neuropathy
Compression:
Coma, prolonged bed rest, crossed legs
Trauma
Systemic disorders:
HNPP, DM, Leprosy
Foot drop, steppage gait
NCS/EMG
Rx:
33. 12/13/2022
(1) Acute Idiopathic Inflammatory
Polyneuropathy (GBS or AIDP)
Clinical Features:
Acute to subacute
Preceding illness (Flue, GI, Vaccine..)
Distal ascending symmetric weakness
Respiratory involvement
Sensory complaints>finding
Absent reflexes
Autonomic
CN
34. 12/13/2022
Cont GBS
Dx:
CSF protein
Normal CSF cell count (<10)
NCS:
Slow motor velocity
HIV-1 in suspected patients
Rx:
Plasmapharesis, IVIG
Symptomatic: Respiratory, DVT,
Autonomic, Nutrition....
Prognosis:
35. 12/13/2022
(2) Chronic inflammatory Demyelinating
Polyneuropathy (CIDP)
Chronic progressive or relapsing course
Similar to GBS
Similar CSF
Electrodiagnosis:
Demyelinating & axonal
Steroids
Plasma exchange, IVIG
Immunosuppression
36. 12/13/2022
(3) Diabetic Neuropathies
0-93% may develop PN
Symmetric PN:
Mixed (most common)
Predominantly sensory
Autonomic
Asymmetric neuropathy:
Mononeuropathy multiplex
Lumbar radiculopathy (2nd common)
Cranial Neuropathy