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   WHO/HIV/2012.28	
  
Annex	
  7:	
  	
  Search	
  Strategies	
  
	
  
General	
  Procedures	
  (Applicable	
  to	
  all	
  PICO	
  Questions)	
  
The	
  researchers	
  searched	
  the	
  following	
  electronic	
  databases	
  the	
  date	
  ranges	
  used	
  varied	
  by	
  
question:	
  	
  
PubMed,	
  PsycINFO,	
  Sociological	
  Abstracts,	
  the	
  Cochrane	
  Central	
  Database	
  of	
  Systematic	
  Reviews,	
  
CINAHL	
  (Cumulative	
  Index	
  to	
  Nursing	
  and	
  Allied	
  Health	
  Literature),	
  and	
  EMBASE	
  
For	
  the	
  serosorting	
  question,	
  hand	
  searching	
  in	
  the	
  following	
  journals	
  was	
  also	
  conducted	
  for	
  years	
  
1990-­‐2009:	
  AIDS,	
  JAIDS,	
  AIDS	
  and	
  Behaviour,	
  AIDS	
  Education	
  and	
  Prevention,	
  and	
  AIDS	
  Care.	
  
For	
  the	
  sex	
  venue,	
  internet-­‐based,	
  and	
  social	
  marketing	
  interventions	
  the	
  following	
  databases	
  were	
  
also	
  used:	
  LILACS	
  (Latin	
  America	
  and	
  Brasil),	
  Web	
  of	
  Science	
  /	
  Web	
  of	
  Social	
  Science,	
  China	
  National	
  
Knowledge	
  Infrastructure	
  (CNKI),	
  CQ	
  VIP	
  (China)	
  
	
  
Medical	
  subject	
  headings	
  (MeSH)	
  were	
  used	
  in	
  addition	
  to	
  key	
  words	
  to	
  maximize	
  sensitivity	
  and	
  
specificity	
  of	
  searches.	
  	
  	
  
MeSH	
  terms	
  and	
  keywords	
  were	
  PICO	
  question-­‐specific	
  (see	
  below	
  for	
  terms	
  used).	
  	
  
Secondary	
  reference	
  searching	
  was	
  also	
  conducted	
  on	
  all	
  articles	
  included	
  in	
  the	
  review	
  as	
  well	
  as	
  in	
  
past	
  systematic	
  reviews	
  and	
  meta-­‐analyses.	
  	
  
Conferences	
  searched	
  included:	
  
International	
  AIDS	
  Conference	
  
Conference	
  on	
  HIV	
  Pathogenesis,	
  Treatment,	
  and	
  Prevention	
  
Conference	
  on	
  Retroviruses	
  and	
  Opportunistic	
  Infections	
  
For	
  the	
  sex	
  venue,	
  internet-­‐based,	
  and	
  social	
  marketing	
  interventions	
  the	
  following	
  databases	
  were	
  
also	
  used:	
  British	
  HIV/AIDS	
  Association,	
  2001-­‐2008,	
  Conference	
  on	
  Retroviruses	
  and	
  Opportunistic	
  
Infections	
  (CROI),	
  1994-­‐2008,	
  European	
  AIDS	
  Society	
  Conference,	
  2001	
  and	
  2003,	
  International	
  AIDS	
  
Society,	
  International	
  AIDS	
  Conference	
  (IAC),	
  1994-­‐2004,	
  International	
  AIDS	
  Society,	
  Conference	
  on	
  
HIV	
  Pathogenesis,	
  Treatment	
  and	
  Prevention	
  (IAS),	
  2001-­‐2005,	
  US	
  National	
  HIV	
  Prevention	
  
Conference,	
  1999,	
  2003,	
  and	
  2005	
  as	
  well	
  as	
  CROI	
  and	
  International	
  AIDS	
  Society	
  web	
  sites	
  for	
  
abstracts	
  presented	
  at	
  conferences	
  subsequent	
  to	
  those	
  listed	
  above	
  (CROI,	
  2009-­‐2010;	
  IAC,	
  2006-­‐
2010;	
  IAS,	
  2007-­‐2009).	
  
	
  
Articles	
  and	
  citations	
  were	
  downloaded,	
  organized,	
  and	
  reviewed.	
  	
  	
  
 
	
  
2	
  
	
  
Inclusion	
  criteria	
  
To	
  be	
  included	
  in	
  the	
  systematic	
  review	
  and	
  GRADEing	
  processes,	
  an	
  article	
  meet	
  the	
  following	
  
criteria:	
  
Published	
  in	
  a	
  peer-­‐reviewed	
  journal,	
  or	
  presented	
  as	
  an	
  abstract	
  at	
  a	
  scientific	
  conference	
  only	
  if	
  
additional	
  information	
  could	
  be	
  gleaned	
  from	
  the	
  author.	
  
Include	
  information	
  that	
  is	
  pertinent	
  to	
  at	
  least	
  1	
  PICO	
  question	
  of	
  interest.	
  
	
  
Screening	
  abstracts	
  
Two	
  independent	
  reviewers	
  screened	
  the	
  titles	
  and	
  abstracts	
  of	
  citations	
  identified	
  through	
  the	
  
search	
  strategy	
  for	
  potential	
  eligibility.	
  	
  Full	
  text	
  articles	
  were	
  obtained	
  for	
  all	
  selected	
  abstracts;	
  
each	
  article	
  was	
  reviewed	
  by	
  two	
  independent	
  reviewers	
  to	
  determine	
  eligibility	
  given	
  the	
  above	
  
inclusion	
  criteria.	
  Differences	
  between	
  the	
  two	
  reviewers	
  were	
  discussed	
  and	
  resolved	
  through	
  
consensus.	
  	
  	
  
	
  
Data	
  extraction	
  and	
  management	
  
Data	
  were	
  extracted	
  by	
  two	
  reviewers	
  using	
  standardized	
  data	
  extraction	
  spreadsheets.	
  Differences	
  
in	
  data	
  extraction	
  will	
  be	
  resolved	
  through	
  consensus.	
  The	
  following	
  information	
  was	
  gathered	
  from	
  
each	
  included	
  study:	
  
Study	
  identification;	
  author(s);	
  type	
  of	
  citation;	
  year	
  of	
  publication	
  
Study	
  description:	
  Location,	
  setting	
  &	
  target	
  group;	
  years	
  (period	
  of	
  study);	
  description	
  of	
  the	
  
intervention;	
  comparison	
  groups;	
  study	
  design;	
  sample	
  size;	
  age	
  range,	
  gender;	
  random	
  or	
  non-­‐
random	
  allocation	
  of	
  participants;	
  length	
  of	
  follow-­‐up	
  (all	
  if	
  applicable)	
  
Outcomes	
  and	
  results:	
  Outcome	
  measures;	
  effect	
  sizes;	
  confidence	
  intervals;	
  significance	
  levels	
  
Other	
  information:	
  limitations;	
  references	
  for	
  follow-­‐up;	
  secondary	
  effects/adverse	
  effects	
  
	
  
Search	
  terms	
  by	
  PICO	
  question	
  
	
  
Questions	
  1	
  and	
  2	
  
	
  
 
	
  
3	
  
Search	
  strategy	
  for	
  The	
  Cochrane	
  Library	
  
Date:	
  February	
  2011	
  
Hepatitis	
  C	
  	
  &	
  B	
  	
   Searches	
  
1	
   MeSH	
  descriptor	
  Hepatitis	
  B	
  explode	
  all	
  trees	
  
2	
   MeSH	
  descriptor	
  Hepatitis	
  B	
  virus	
  explode	
  all	
  trees	
  
3	
   Hbv:ti,ab	
  
4	
   Chb:ti,ab	
  
5	
   MeSH	
  descriptor	
  Hepacivirus	
  explode	
  all	
  trees	
  
6	
   MeSH	
  descriptor	
  Hepatitis	
  C	
  explode	
  all	
  trees	
  
7	
   Hepatitis:ab,ti	
  
8	
   HCV.ti,ab,kw	
  
9	
   CHC:ti,ab	
  
10	
   #1	
  OR	
  #2	
  OR	
  #3	
  OR	
  #4	
  OR	
  #5	
  OR	
  #6	
  OR	
  #7	
  OR	
  #8	
  OR	
  #9	
  	
  
PWID	
  filter	
   	
  
11	
   MeSH	
  descriptor	
  Substance-­‐related	
  disorder	
  explode	
  all	
  trees	
  
12	
   Drug:ti,ab,kw	
  OR	
  substance:ti,ab,kw	
  OR	
  heroin:ti,ab,kw	
  OR	
  cocaine:ti,ab,kw	
  OR	
  
opioid*:ti,ab,kw	
  OR	
  opiate*:ti,ab,kw	
  or	
  methadone:ti,ab,kw	
  OR	
  narcotic*:ti,ab,kw	
  OR	
  
PWID:ti,ab,kw	
  OR	
  psychostimulant*:ti,ab,kw	
  or	
  crack:ti,ab,kw	
  or	
  IDU:ti,ab,kw	
  	
  OR	
  
morphine:	
  ti,ab,kw	
  	
  	
  
13	
   addict*:ti,ab	
  OR	
  abus*:ti,ab	
  OR	
  user*:ti,ab	
  OR	
  inject*:ti,ab	
  	
  OR	
  dependen*:ti,ab	
  or	
  
disorder*:ti,ab	
  	
  OR	
  overdos*:ti,ab	
  
14	
   #12	
  AND	
  #13	
  
15	
   #11	
  OR	
  #14	
  
Vaccination	
  
filter	
  
	
  
16	
   "Immunization"[Mesh]	
  
17	
   Immunization:ti,ab	
  or	
  vaccinat*:ti,ab	
  OR	
  immunisation:ti,ab	
  OR	
  immunotherapy[tiab]	
  	
  	
  
18	
   MeSH	
  descriptor	
  Immunization	
  Programs	
  explode	
  all	
  trees	
  
	
  	
  	
  
19	
   #16	
  OR	
  #17	
  OR	
  #18	
  
 
	
  
4	
  
Filter	
  for	
  
intervention	
  
	
  
20	
   incentive*:ti,ab	
  OR	
  voucher*:ti,ab	
  OR	
  contingen*:ti,ab	
  or	
  money:ti,ab	
  	
  
Motivation*:ti,ab	
  OR	
  inducement[tiab]	
  OR	
  reward[tiab]	
  OR	
  prize	
  [tiab]	
  
21	
   MeSH	
  descriptor	
  "Reimbursement,	
  Incentive"	
  explode	
  all	
  trees	
  
22	
   #20	
  OR	
  #21	
  	
  
23	
   #10	
  AND	
  #15	
  AND	
  #19	
  	
  
24	
   #10	
  AND	
  #15	
  AND	
  #19	
  AND	
  #23	
  
	
  
	
  
Search	
  strategy	
  for	
  PubMed:	
  
Date:	
  February	
  2011	
  
#	
   Searches	
  
Hepatitis	
  C	
  filter:	
   	
  
1	
   Hepatitis	
  C[Mesh]	
  
2	
   Hepatitis	
  C,	
  Chronic[Mesh]	
  
3	
   "hep	
  C"[tiab]	
  
4	
   HCV[All	
  Fields]	
  
5	
   "HCV-­‐DNA"[All	
  Fields]	
  
6	
   "CHC"[All	
  Fields]	
  
7	
   hepatitis[tiab]	
  
8	
   Hepacivirus[MESH]	
  
Hepatitis	
  B	
  filter:	
   	
  
9	
   "Hepatitis	
  B"[MeSH	
  Terms]	
  
10	
   "Hepatitis	
  B,	
  Chronic"[MeSH	
  Terms]	
  
11	
   "hep	
  B”[tiab]	
  
12	
   HBV[tiab]	
  
13	
   "HBV-­‐DNA"[tiab]	
  
 
	
  
5	
  
14	
   CHB[tiab]	
  
15	
   #1	
  OR	
  #2	
  OR	
  #3	
  OR	
  #4	
  OR	
  #5	
  OR	
  #6	
  OR	
  #7	
  OR	
  #8	
  OR	
  #9	
  OR	
  #10	
  OR	
  #11	
  or	
  #12	
  or	
  
#13	
  or	
  #14	
  
PWID	
  filter	
   	
  
16	
   Substance-­‐related	
  disorder[mesh]	
  
17	
   addict*[tiab]	
  OR	
  abuse[tiab]	
  OR	
  user*[tiab]	
  OR	
  inject*[tiab]	
  OR	
  dependen*[tiab]	
  
or	
  disorder*[tiab]	
  or	
  overdos*[tiab]	
  
18	
   drug	
  [tw]	
  OR	
  alcohol	
  [tw]	
  OR	
  substance	
  [tw]	
  OR	
  amphetamine*[tw]	
  OR	
  
cocaine[tw]	
  OR	
  opioid*[tw]	
  OR	
  opiate*[tw]	
  or	
  methadone[tw]	
  OR	
  narcotic*[tw]	
  
OR	
  PWID[tw]	
  OR	
  psychostimulant*[tw]	
  or	
  crack[tiab]	
  or	
  IDU[tiab]	
  or	
  morphine	
  
[tiab]	
  
19	
   #18	
  AND	
  #17	
  
20	
   #16	
  OR	
  #19	
  
Vaccination	
  filter	
   	
  
21	
   "Immunization"[Mesh]	
  
22	
   "Immunization	
  Programs"[Mesh]	
  
23	
   Immunization[tiab]	
  or	
  vaccinat*[tiab]	
  OR	
  immunisation[tiab]	
  or	
  
immunotherapy[tiab]	
  
24	
   #21	
  OR	
  #22	
  OR	
  #23	
  
Filter	
  for	
  intervention	
   	
  
25	
   incentive*[TIAB]	
  OR	
  voucher*[tiab]	
  OR	
  contingen*[tiab]	
  or	
  money[tiab]	
  
Motivation*[tiab]	
  OR	
  inducement[tiab]	
  OR	
  reward[tiab]	
  OR	
  prize	
  [tiab]	
  
26	
   "Reimbursement,	
  Incentive"[Mesh]	
  
27	
   #25	
  OR	
  #26	
  	
  
28	
   #15	
  AND	
  #20	
  AND	
  #24	
  
29	
   #15	
  AND	
  #20	
  AND	
  #24	
  AND	
  #27	
  
30	
   Animals[mesh]	
  NOT	
  humans[mesh]	
  
31	
   #28	
  NOT	
  #30	
  
32	
   #29	
  NOT	
  #30	
  
	
  
	
  
 
	
  
6	
  
Search	
  strategy	
  for	
  EMBASE	
  	
  
Date:	
  February	
  2011	
  
Hepatitis	
  
filter	
  
	
  
1	
   'hepatitis	
  c'/exp	
  OR	
  'hepatitis	
  c'	
  OR	
  'hep	
  c'	
  OR	
  'hcv'	
  OR	
  'chc'	
  OR	
  'hepatitis'/exp	
  OR	
  
'hepatitis'	
  OR	
  'hepacivirus':ab,ti	
  OR	
  'hepatitis	
  b'/exp	
  OR	
  'hepatitis	
  b'	
  OR	
  'hep	
  b':ab,ti	
  OR	
  
'hbv':ab,ti	
  OR	
  'chb':ab,ti	
  OR	
  'hepatitis	
  virus	
  non	
  a	
  non	
  b'/exp	
  OR	
  'hepatitis	
  virus	
  non	
  a	
  
non	
  b'	
  OR	
  'hepatitis	
  b	
  virus'/exp	
  OR	
  'hepatitis	
  b	
  virus'	
  OR	
  'hepatitis	
  c	
  virus'/exp	
  OR	
  
'hepatitis	
  c	
  virus'	
  OR	
  'hepatitis	
  virus'/exp	
  OR	
  'hepatitis	
  virus'	
  
PWID	
  filter	
   	
  
2	
   'drug	
  abuse'/exp	
  OR	
  'drug	
  abuse'	
  OR	
  addict*:ab,ti	
  OR	
  abuse:ab,ti	
  OR	
  user*:ab,ti	
  OR	
  
inject*:ab,ti	
  OR	
  dependen*:ab,ti	
  OR	
  disorder*:ab,ti	
  AND	
  ('drug'/exp	
  OR	
  drug	
  OR	
  
substance	
  OR	
  'cocaine'/exp	
  OR	
  cocaine	
  OR	
  opioid*	
  OR	
  opiate*	
  OR	
  'methadone'/exp	
  OR	
  
methadone	
  OR	
  narcotic*	
  OR	
  pwid	
  OR	
  psychostimulant*	
  OR	
  crack:ab,ti	
  OR	
  idu:ab,ti	
  OR	
  
morphine:	
  ab,ti	
  )	
  
3	
   	
  	
  	
  #1	
  AND	
  #2	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
Vaccination	
  
filter	
  
	
  
4	
   Immunization:ti,ab	
  or	
  vaccinat*:ti,ab	
  OR	
  immunisation:ti,ab	
  OR	
  immunotherapy[tiab]	
  
Filter	
  for	
  
intervention	
  
	
  
5	
   incentive*:ti,ab	
  OR	
  voucher*:ti,ab	
  OR	
  contingen*:ti,ab	
  or	
  money:ti,ab	
  	
  Motivation*:ti,ab	
  
OR	
  inducement:ti,ab	
  OR	
  reward:ti,ab	
  OR	
  prize:ti,ab	
  or	
  reimbursement:ti,ab	
  
6	
   #3	
  AND	
  #4	
  	
  
7	
   #3	
  AND	
  #4	
  AND	
  #5	
  
	
  
	
  
Search	
  strategy	
  for	
  CINAHL	
  	
  
Date:	
  February	
  2011	
  
Hepatitis	
  filter	
   Searches	
  
1	
   MH	
  Hepatitis	
  B	
  	
  
2	
   MH	
  Hepatitis	
  C	
  
 
	
  
7	
  
3	
   TW	
  Hepatitis	
  	
  
4	
   TX	
  ‘hep	
  b’	
  
5	
   TX	
  ‘hep	
  C’	
  
6	
   TX	
  Hbv	
  
7	
   TX	
  Chb	
  
8	
   TX	
  HCV	
  
9	
   TX	
  CHC	
  
10	
   1	
  OR	
  2	
  OR	
  3	
  OR	
  4	
  OR	
  5	
  OR	
  6	
  OR	
  7	
  OR	
  8	
  OR	
  9	
  
PWID	
  filter	
   	
  
11	
   (MM	
  "Substance	
  Abuse,	
  Intravenous")	
  
12	
   (MM	
  "Intravenous	
  Drug	
  Users")	
  
13	
   TX	
  drug	
  OR	
  TX	
  substance	
  OR	
  TX	
  cocaine	
  OR	
  TX	
  opioid*	
  OR	
  TX	
  opiate*	
  OR	
  TX	
  methadone	
  
OR	
  TX	
  narcotic*	
  OR	
  TX	
  PWID	
  OR	
  TX	
  psychostimulant*	
  OR	
  TX	
  crack	
  OR	
  TX	
  IDU	
  or	
  TX	
  
morphine	
  OR	
  TX	
  narcotic*	
  
14	
   TX	
  addict*	
  OR	
  TX	
  abus*	
  OR	
  TX	
  user*	
  OR	
  TX	
  inject*	
  	
  OR	
  TX	
  dependen*	
  OR	
  TX	
  disorder*	
  
OR	
  TX	
  overdose	
  
15	
   13	
  AND	
  14	
  
16	
   11	
  OR	
  12	
  OR	
  15	
  
Vaccination	
  
filter	
  
	
  
17	
   (MH	
  "Immunization+")	
  
18	
   TX	
  Immunization	
  or	
  TX	
  vaccinat*	
  OR	
  TX	
  immunisation	
  OR	
  TX	
  immunotherapy	
  
19	
   17	
  OR	
  18	
  
Filter	
  for	
  
intervention	
  
	
  
20	
   TX	
  incentive*	
  OR	
  TX	
  voucher*	
  OR	
  TX	
  contingen*	
  or	
  TX	
  money	
  	
  TX	
  Motivation*	
  OR	
  TX	
  
inducement	
  OR	
  TX	
  reward:ti,ab	
  TX	
  prize	
  or	
  TX	
  reimbursement	
  
21	
   10	
  AND	
  16	
  AND	
  19	
  
22	
   10	
  AND	
  16	
  AND	
  19	
  AND	
  20	
  
	
  
	
  
 
	
  
8	
  
Search	
  strategy	
  for	
  WHO	
  regional	
  databases	
  
Date:	
  October	
  2010	
  
#	
   Searches	
  
LILACS	
   (	
  (	
  (	
  (	
  "HEPATITIS	
  B"	
  )	
  or	
  "HEPATITIS	
  B,	
  chronic"	
  )	
  or	
  "HEPATITIS	
  C"	
  )	
  or	
  "hepatitis	
  
c,	
  chronic"	
  )	
  or	
  "HEPACIVIRUS"	
  [Subject	
  descriptor]	
  or	
  "CHC"	
  or	
  "HCV"	
  or	
  
"HEPATITIS	
  B"	
  or	
  "HEPATITIS	
  C"	
  or	
  "HBV"	
  or	
  "CHB"	
  [Words]	
  and	
  (	
  (	
  (	
  "SEROLOGIC	
  
TESTS"	
  )	
  or	
  "DIAGNOSTIC	
  TESTs,	
  routine"	
  )	
  or	
  "HEPATITIS	
  ANTIGENS"	
  )	
  or	
  
"HEPATITIS	
  ANTIBODIES"	
  [Subject	
  descriptor]	
  
African	
  Index	
  Medicus	
  
Index	
  Medicus	
  for	
  the	
  
Eastern	
  
Mediterranean	
  Region	
  
(Hepatitis	
  or	
  Hep*)	
  	
  
	
  
Question	
  3	
  
	
  
	
  
Search	
  strategy	
  for	
  The	
  Cochrane	
  Library	
  
Date:	
  September	
  2011	
  
Hepatitis	
  C	
  	
  &	
  B	
  	
   Searches	
  
1	
   MeSH	
  descriptor	
  Hepatitis	
  B	
  explode	
  all	
  trees	
  
2	
   MeSH	
  descriptor	
  Hepatitis	
  B	
  virus	
  explode	
  all	
  trees	
  
3	
   Hbv:ti,ab	
  
4	
   Chb:ti,ab	
  
5	
   MeSH	
  descriptor	
  Hepacivirus	
  explode	
  all	
  trees	
  
6	
   MeSH	
  descriptor	
  Hepatitis	
  C	
  explode	
  all	
  trees	
  
7	
   Hepatitis:ab,ti	
  
8	
   HCV.ti,ab,kw	
  
9	
   CHC:ti,ab	
  
10	
   #1	
  OR	
  #2	
  OR	
  #3	
  OR	
  #4	
  OR	
  #5	
  OR	
  #6	
  OR	
  #7	
  OR	
  #8	
  OR	
  #9	
  	
  
HIV	
   	
  
 
	
  
9	
  
11	
   MeSH	
  descriptor	
  HIV	
  Infections	
  explode	
  all	
  trees	
  
12	
   MeSH	
  descriptor	
  HIV	
  explode	
  all	
  trees	
  
13	
   HIV	
  
14	
   MeSH	
  descriptor	
  Acquired	
  Immunodeficiency	
  Syndrome	
  explode	
  all	
  trees	
  
15	
   #11	
  OR	
  #12	
  OR	
  #13	
  OR	
  #14	
  
PWID	
  filter	
   	
  
16	
   MeSH	
  descriptor	
  Substance-­‐related	
  disorder	
  explode	
  all	
  trees	
  
17	
   Drug:ti,ab,kw	
  OR	
  substance:ti,ab,kw	
  OR	
  heroin:ti,ab,kw	
  OR	
  cocaine:ti,ab,kw	
  OR	
  
opioid*:ti,ab,kw	
  OR	
  opiate*:ti,ab,kw	
  or	
  methadone:ti,ab,kw	
  OR	
  narcotic*:ti,ab,kw	
  OR	
  
PWID:ti,ab,kw	
  OR	
  psychostimulant*:ti,ab,kw	
  or	
  crack:ti,ab,kw	
  or	
  IDU:ti,ab,kw	
  	
  OR	
  
morphine:	
  ti,ab,kw	
  	
  	
  
18	
   addict*:ti,ab	
  OR	
  abus*:ti,ab	
  OR	
  user*:ti,ab	
  OR	
  inject*:ti,ab	
  	
  OR	
  dependen*:ti,ab	
  or	
  
disorder*:ti,ab	
  	
  OR	
  overdos*:ti,ab	
  
19	
   #17	
  AND	
  #18	
  
20	
   #16	
  OR	
  #19	
  
Dead-­‐Space	
  
Syringes	
  
	
  
21	
   MeSH	
  descriptor	
  Syringes	
  explode	
  all	
  trees	
  
22	
   MeSH	
  descriptor	
  Needle	
  Sharing	
  explode	
  all	
  trees	
  
23	
   	
  
syringe	
  next	
  type	
  
24	
   (dead	
  AND	
  space	
  AND	
  syringe*)	
  
25	
   #21	
  OR	
  #22	
  OR	
  #23	
  OR	
  #24	
  
26	
   #10	
  OR	
  #15	
  
27	
   #20	
  AND	
  #25	
  AND	
  #26	
  
	
  
	
  
Search	
  strategy	
  for	
  PubMed:	
  
Date:	
  September	
  2011	
  
#	
   Searches	
  
 
	
  
10	
  
Hepatitis	
  C	
  filter:	
   	
  
1	
   Hepatitis	
  C[Mesh]	
  
2	
   Hepatitis	
  C,	
  Chronic[Mesh]	
  
3	
   "hep	
  C"[tiab]	
  
4	
   HCV[All	
  Fields]	
  
5	
   "HCV-­‐DNA"[All	
  Fields]	
  
6	
   "CHC"[All	
  Fields]	
  
7	
   hepatitis[tiab]	
  
8	
   Hepacivirus[MESH]	
  
Hepatitis	
  B	
  filter:	
   	
  
9	
   "Hepatitis	
  B"[MeSH	
  Terms]	
  
10	
   "Hepatitis	
  B,	
  Chronic"[MeSH	
  Terms]	
  
11	
   "hep	
  B”[tiab]	
  
12	
   HBV[tiab]	
  
13	
   "HBV-­‐DNA"[tiab]	
  
14	
   CHB[tiab]	
  
HIV	
   	
  
15	
   HIV	
  Infections[MeSH]	
  OR	
  HIV[MeSH]	
  OR	
  hiv[tw]	
  OR	
  hiv1[tw]	
  OR	
  hiv2[tw]	
  OR	
  human	
  
immunodeficiency	
  virus[tw]	
  OR	
  human	
  immunedeficiency	
  virus[tw]	
  OR	
  ((human	
  immun*)	
  
AND(deficiency	
  virus[tw]))OR	
  acquired	
  immunodeficiency	
  syndrome[tw]OR	
  acquired	
  
immunedeficiency	
  syndrome[tw]OR	
  acquired	
  immuno-­‐deficiency	
  syndrome[tw]	
  OR	
  
acquired	
  immune-­‐deficiency	
  syndrome[tw]	
  OR	
  ((acquired	
  immun*)	
  AND	
  (deficiency	
  
syndrome[tw])	
  )	
  
16	
   #1	
  OR	
  #2	
  OR	
  #3	
  OR	
  #4	
  OR	
  #5	
  OR	
  #6	
  OR	
  #7	
  OR	
  #8	
  OR	
  #9	
  OR	
  #10	
  OR	
  #11	
  OR	
  #12	
  
OR	
  #13	
  OR	
  #14	
  OR	
  #15	
  
PWID	
  filter	
   	
  
17	
   Substance-­‐related	
  disorder[mesh]	
  
18	
   addict*[tiab]	
  OR	
  abuse[tiab]	
  OR	
  user*[tiab]	
  OR	
  inject*[tiab]	
  OR	
  dependen*[tiab]	
  
or	
  disorder*[tiab]	
  or	
  overdos*[tiab]	
  
19	
   drug	
  [tw]	
  OR	
  alcohol	
  [tw]	
  OR	
  substance	
  [tw]	
  OR	
  amphetamine*[tw]	
  OR	
  
cocaine[tw]	
  OR	
  opioid*[tw]	
  OR	
  opiate*[tw]	
  or	
  methadone[tw]	
  OR	
  narcotic*[tw]	
  
OR	
  PWID[tw]	
  OR	
  psychostimulant*[tw]	
  or	
  crack[tiab]	
  or	
  IDU[tiab]	
  or	
  morphine	
  
 
	
  
11	
  
[tiab]	
  
20	
   #18	
  AND	
  #19	
  
21	
   #17	
  OR	
  #20	
  
Dead-­‐Space	
  Syringes	
   	
  
22	
   "Syringes"[Mesh]	
  
23	
   "Needle	
  Sharing"[Mesh]	
  
24	
   (dead	
  AND	
  space	
  AND	
  syringe*)	
  
25	
   LDSS[tiab]	
  OR	
  hdss[tiab]	
  
26	
   #22	
  OR	
  #23	
  OR	
  #24	
  OR	
  #25	
  
27	
   #16	
  AND	
  #21	
  AND	
  #26	
  
	
  
	
  
Search	
  strategy	
  for	
  EMBASE	
  	
  
Date:	
  September	
  2011	
  
Hepatitis	
  
filter	
  
	
  
1	
   'hepatitis	
  c'/exp	
  OR	
  'hepatitis	
  c'	
  OR	
  'hep	
  c'	
  OR	
  'hcv'	
  OR	
  'chc'	
  OR	
  'hepatitis'/exp	
  OR	
  
'hepatitis'	
  OR	
  'hepacivirus':ab,ti	
  OR	
  'hepatitis	
  b'/exp	
  OR	
  'hepatitis	
  b'	
  OR	
  'hep	
  b':ab,ti	
  OR	
  
'hbv':ab,ti	
  OR	
  'chb':ab,ti	
  OR	
  'hepatitis	
  virus	
  non	
  a	
  non	
  b'/exp	
  OR	
  'hepatitis	
  virus	
  non	
  a	
  
non	
  b'	
  OR	
  'hepatitis	
  b	
  virus'/exp	
  OR	
  'hepatitis	
  b	
  virus'	
  OR	
  'hepatitis	
  c	
  virus'/exp	
  OR	
  
'hepatitis	
  c	
  virus'	
  OR	
  'hepatitis	
  virus'/exp	
  OR	
  'hepatitis	
  virus'	
  
HIV	
  filter	
   	
  
2	
   'human	
  immunodeficiency	
  virus	
  infection'/exp	
  OR	
  'hiv':ab,ti	
  OR	
  'human	
  
immunodeficiency	
  virus':ab,ti	
  OR	
  'human	
  immuno-­‐deficiency	
  virus':ab,ti	
  OR	
  'human	
  
immune-­‐deficiency	
  virus':ab,ti	
  OR	
  'acquired	
  immune-­‐deficiency	
  syndrome':ab,ti	
  OR	
  
'acquired	
  immunedeficiency	
  syndrome':ab,ti	
  OR	
  'acquired	
  immuno-­‐deficiency	
  
syndrome':ab,ti	
  AND	
  [embase]/lim	
  
3	
   #1	
  OR	
  #2	
  
PWID	
  filter	
   	
  
4	
   'drug	
  abuse'/exp	
  OR	
  'drug	
  abuse'	
  OR	
  addict*:ab,ti	
  OR	
  abuse:ab,ti	
  OR	
  user*:ab,ti	
  OR	
  
inject*:ab,ti	
  OR	
  dependen*:ab,ti	
  OR	
  disorder*:ab,ti	
  AND	
  ('drug'/exp	
  OR	
  drug	
  OR	
  
substance	
  OR	
  'cocaine'/exp	
  OR	
  cocaine	
  OR	
  opioid*	
  OR	
  opiate*	
  OR	
  'methadone'/exp	
  OR	
  
methadone	
  OR	
  narcotic*	
  OR	
  pwid	
  OR	
  psychostimulant*	
  OR	
  crack:ab,ti	
  OR	
  idu:ab,ti	
  OR	
  
 
	
  
12	
  
morphine:	
  ab,ti	
  )	
  
5	
   	
  	
  	
  #3	
  AND	
  #4	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
Dead-­‐Space	
  
Syringes	
  
	
  
6	
   'syringe'/exp	
  OR	
  'syringe'	
  
7	
   'needle	
  sharing':ab,ti	
  
8	
   dead:ab,ti	
  AND	
  space:ab,ti	
  AND	
  syringe*:ab,ti	
  
9	
   'ldss':ab,ti	
  OR	
  'hdss':ab,ti	
  
10	
   #6	
  OR	
  #7	
  OR	
  #8	
  OR	
  #9	
  
11	
   #5	
  AND	
  #10	
  
	
  
	
  
Search	
  strategy	
  for	
  CINAHL	
  	
  
Date:	
  September	
  2011	
  
Hepatitis	
  filter	
   Searches	
  
1	
   MH	
  Hepatitis	
  B	
  	
  
2	
   MH	
  Hepatitis	
  C	
  
3	
   TW	
  Hepatitis	
  	
  
4	
   TX	
  ‘hep	
  b’	
  
5	
   TX	
  ‘hep	
  C’	
  
6	
   TX	
  Hbv	
  
7	
   TX	
  Chb	
  
8	
   TX	
  HCV	
  
9	
   TX	
  CHC	
  
10	
   1	
  OR	
  2	
  OR	
  3	
  OR	
  4	
  OR	
  5	
  OR	
  6	
  OR	
  7	
  OR	
  8	
  OR	
  9	
  
Hiv	
  filter	
   	
  
11	
   (MH	
  "HIV	
  Infections+")	
  
12	
   (MH	
  "Human	
  Immunodeficiency	
  Virus+")	
  
 
	
  
13	
  
13	
   (MH	
  "Acquired	
  Immunodeficiency	
  Syndrome")	
  
14	
   TX	
  HIV	
  
15	
   11	
  OR	
  12	
  OR	
  13	
  OR	
  14	
  	
  
16	
   10	
  OR	
  15	
  
PWID	
  filter	
   	
  
17	
   (MM	
  "Substance	
  Abuse,	
  Intravenous")	
  
18	
   (MM	
  "Intravenous	
  Drug	
  Users")	
  
19	
   TX	
  drug	
  OR	
  TX	
  substance	
  OR	
  TX	
  cocaine	
  OR	
  TX	
  opioid*	
  OR	
  TX	
  opiate*	
  OR	
  TX	
  methadone	
  
OR	
  TX	
  narcotic*	
  OR	
  TX	
  PWID	
  OR	
  TX	
  psychostimulant*	
  OR	
  TX	
  crack	
  OR	
  TX	
  IDU	
  or	
  TX	
  
morphine	
  OR	
  TX	
  narcotic*	
  
20	
   TX	
  addict*	
  OR	
  TX	
  abus*	
  OR	
  TX	
  user*	
  OR	
  TX	
  inject*	
  	
  OR	
  TX	
  dependen*	
  OR	
  TX	
  disorder*	
  
OR	
  TX	
  overdose	
  
21	
   19	
  AND	
  20	
  
22	
   17	
  OR	
  18OR	
  21	
  
Dead-­‐Space	
  
Syringes	
  
	
  
23	
   (MH	
  "Syringes")	
  
24	
   (MH	
  "Needle	
  Sharing")	
  
25	
   (dead	
  AND	
  space	
  AND	
  syringe*)	
  
26	
   TI	
  LDSS	
  OR	
  AB	
  LDSS	
  OR	
  TI	
  HDSS	
  OR	
  AB	
  HDSS	
  
27	
   23	
  OR	
  24	
  OR	
  25	
  OR	
  26	
  
28	
   16	
  AND	
  22	
  AND	
  26	
  
	
  
	
  
Questions	
  4	
  and	
  5	
  
	
  
	
  
Search	
  strategy	
  for	
  The	
  Cochrane	
  Library	
  
Date:	
  February	
  2011	
  
 
	
  
14	
  
Hepatitis	
  C	
  	
  &	
  B	
  	
   Searches	
  
1	
   MeSH	
  descriptor	
  Hepatitis	
  B	
  explode	
  all	
  trees	
  
2	
   MeSH	
  descriptor	
  Hepatitis	
  B	
  virus	
  explode	
  all	
  trees	
  
3	
   Hbv:ti,ab	
  
4	
   Chb:ti,ab	
  
5	
   MeSH	
  descriptor	
  Hepacivirus	
  explode	
  all	
  trees	
  
6	
   MeSH	
  descriptor	
  Hepatitis	
  C	
  explode	
  all	
  trees	
  
7	
   Hepatitis:ab,ti	
  
8	
   HCV.ti,ab,kw	
  
9	
   CHC:ti,ab	
  
10	
   #1	
  OR	
  #2	
  OR	
  #3	
  OR	
  #4	
  OR	
  #5	
  OR	
  #6	
  OR	
  #7	
  OR	
  #8	
  OR	
  #9	
  	
  
PWID	
  filter	
   	
  
11	
   MeSH	
  descriptor	
  Substance-­‐related	
  disorder	
  explode	
  all	
  trees	
  
12	
   Drug:ti,ab,kw	
  OR	
  substance:ti,ab,kw	
  OR	
  heroin:ti,ab,kw	
  OR	
  cocaine:ti,ab,kw	
  OR	
  
opioid*:ti,ab,kw	
  OR	
  opiate*:ti,ab,kw	
  or	
  methadone:ti,ab,kw	
  OR	
  narcotic*:ti,ab,kw	
  OR	
  
PWID:ti,ab,kw	
  OR	
  psychostimulant*:ti,ab,kw	
  or	
  crack:ti,ab,kw	
  or	
  IDU:ti,ab,kw	
  	
  OR	
  
morphine:	
  ti,ab,kw	
  	
  	
  
13	
   addict*:ti,ab	
  OR	
  abus*:ti,ab	
  OR	
  user*:ti,ab	
  OR	
  inject*:ti,ab	
  	
  OR	
  dependen*:ti,ab	
  or	
  
disorder*:ti,ab	
  	
  OR	
  overdos*:ti,ab	
  
14	
   #12	
  AND	
  #13	
  
15	
   #11	
  OR	
  #14	
  
Filter	
  for	
  	
  
intervention	
  
	
  
16	
   MeSH	
  descriptor	
  "Psychotherapy,	
  Brief"	
  explode	
  all	
  trees	
  
17	
   MeSH	
  descriptor	
  "Peer	
  Group"	
  explode	
  all	
  trees	
  
18	
   peer*:ti,ab	
  OR	
  "peer	
  support":ti,ab	
  OR	
  motivation*:ti,ab	
  OR	
  "minimal	
  
intervention":ti,ab	
  OR	
  "brief	
  intervention":ti,ab	
  OR	
  testing:ti,ab	
  OR	
  psychosocial:ti,ab	
  
OR	
  adivice:ti,ab	
  OR	
  counseling:ti,ab	
  
19	
   #16	
  OR	
  #17	
  OR	
  #18	
  
20	
   #10	
  AND	
  #15	
  AND	
  #19	
  	
  
	
  
 
	
  
15	
  
	
  
Search	
  strategy	
  for	
  PubMed	
  	
  
Date:	
  February	
  2011	
  
#	
   Searches	
  
Hepatitis	
  C	
  
filter:	
  
	
  
1	
   Hepatitis	
  C[Mesh]	
  
2	
   Hepatitis	
  C,	
  Chronic[Mesh]	
  
3	
   "hep	
  C"[tiab]	
  
4	
   HCV[All	
  Fields]	
  
5	
   "HCV-­‐DNA"[All	
  Fields]	
  
6	
   "CHC"[All	
  Fields]	
  
7	
   hepatitis[tiab]	
  
8	
   Hepacivirus[MESH]	
  
Hepatitis	
  B	
  
filter:	
  
	
  
9	
   "Hepatitis	
  B"[MeSH	
  Terms]	
  
10	
   "Hepatitis	
  B,	
  Chronic"[MeSH	
  Terms]	
  
11	
   "hep	
  B”[tiab]	
  
12	
   HBV[tiab]	
  
13	
   "HBV-­‐DNA"[tiab]	
  
14	
   CHB[tiab]	
  
15	
   #1	
  OR	
  #2	
  OR	
  #3	
  OR	
  #4	
  OR	
  #5	
  OR	
  #6	
  OR	
  #7	
  OR	
  #8	
  OR	
  #9	
  OR	
  #10	
  OR	
  #11	
  or	
  #12	
  OR	
  #13	
  OR	
  
#14	
  
PWID	
  filter	
   	
  
16	
   drug	
  [tw]	
  OR	
  substance	
  [tw]	
  OR	
  cocaine[tw]	
  OR	
  opioid*[tw]	
  OR	
  opiate*[tw]	
  or	
  
methadone[tw]	
  OR	
  narcotic*[tw]	
  OR	
  PWID[tw]	
  OR	
  psychostimulant*[tw]	
  OR	
  crack[tiab]	
  
OR	
  IDU[tiab]	
  or	
  morphine[tw]	
  
17	
   addict*[tiab]	
  OR	
  abuse[tiab]	
  OR	
  user*[tiab]	
  OR	
  inject*[tiab]	
  OR	
  dependen*[tiab]	
  or	
  
disorder*[tiab]	
  OR	
  overdos*[tiab]	
  
 
	
  
16	
  
18	
   16	
  AND	
  17	
  
19	
   Substance-­‐related	
  disorder[mesh]	
  
20	
   #18	
  OR	
  #19	
  
21	
   #15	
  AND	
  #20	
  
Filter	
  for	
  
intervention	
  
	
  
22	
   "Psychotherapy,	
  Brief"[Mesh]	
  
23	
   Counseling[mesh]	
  
24	
   "Peer	
  Group"[Mesh]	
  
25	
   advice[tiab]	
  OR	
  peer*[tiab]	
  OR	
  "peer	
  support"	
  [tiab]	
  OR	
  "Brief	
  intervention"	
  [tiab]	
  OR	
  	
  
"minimal	
  intervention"[tiab]	
  OR	
  motivation[tiab]	
  OR	
  psychosocial[tiab]	
  OR	
  
counseling[tiab]	
  OR	
  test*[tiab]	
  OR	
  testing[tiab]	
  	
  
26	
   #22	
  OR	
  #23	
  OR	
  #24	
  OR	
  #25	
  
27	
   #26	
  AND	
  #21	
  
28	
   Animals[mesh]	
  NOT	
  humans[mesh]	
  
29	
   #27	
  NOT	
  #28	
  	
  
	
  
	
  
Search	
  strategy	
  for	
  EMBASE	
  	
  
Date:	
  February	
  2011	
  
Hepatitis	
  filter:	
   	
  
1	
   'hepatitis	
  c'/exp	
  OR	
  'hepatitis	
  c'	
  OR	
  'hep	
  c'	
  OR	
  'hcv'	
  OR	
  'chc'	
  OR	
  'hepatitis'/exp	
  OR	
  
'hepatitis'	
  OR	
  'hepacivirus':ab,ti	
  OR	
  'hepatitis	
  b'/exp	
  OR	
  'hepatitis	
  b'	
  OR	
  'hep	
  b':ab,ti	
  OR	
  
'hbv':ab,ti	
  OR	
  'chb':ab,ti	
  OR	
  'hepatitis	
  virus	
  non	
  a	
  non	
  b'/exp	
  OR	
  'hepatitis	
  virus	
  non	
  a	
  
non	
  b'	
  OR	
  'hepatitis	
  b	
  virus'/exp	
  OR	
  'hepatitis	
  b	
  virus'	
  OR	
  'hepatitis	
  c	
  virus'/exp	
  OR	
  
'hepatitis	
  c	
  virus'	
  OR	
  'hepatitis	
  virus'/exp	
  OR	
  'hepatitis	
  virus'	
  
PWID	
  filter	
   	
  
2	
   'drug	
  abuse'/exp	
  OR	
  'drug	
  abuse'	
  OR	
  addict*:ab,ti	
  OR	
  abuse:ab,ti	
  OR	
  user*:ab,ti	
  OR	
  
inject*:ab,ti	
  OR	
  dependen*:ab,ti	
  OR	
  disorder*:ab,ti	
  AND	
  ('drug'/exp	
  OR	
  drug	
  OR	
  
substance	
  OR	
  'cocaine'/exp	
  OR	
  cocaine	
  OR	
  opioid*	
  OR	
  opiate*	
  OR	
  'methadone'/exp	
  OR	
  
methadone	
  OR	
  narcotic*	
  OR	
  pwid	
  OR	
  psychostimulant*	
  OR	
  crack:ab,ti	
  OR	
  idu:ab,ti	
  OR	
  
morphine:	
  ab,ti	
  )	
  
 
	
  
17	
  
3	
   	
  	
  	
  #1	
  AND	
  #2	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
Filter	
  for	
  
intervention	
  
	
  
4	
   psychosocial*:ab,ti	
  OR	
  counseling:ab,ti	
  OR	
  advice:	
  ab,ti	
  OR	
  reinforcement:	
  ab,ti	
  	
  OR	
  
motivation*:	
  ab,ti	
  OR	
  education:	
  ab,ti	
  OR	
  psychotherapy:ab,ti	
  OR	
  social:ab,ti	
  OR	
  
peer:ab,ti	
  or	
  brief	
  intervention:	
  ab,ti	
  OR	
  testing:ab,ti	
  or	
  test:ab,ti	
  
	
  
	
  
Search	
  strategy	
  for	
  CINAHL	
  	
  
Date:	
  February	
  2011	
  
#	
   Searches	
  
Hepatitis	
  filter	
   	
  
1	
   MH	
  Hepatitis	
  B	
  	
  
2	
   MH	
  Hepatitis	
  C	
  
3	
   TW	
  Hepatitis	
  	
  
4	
   TW	
  ‘hep	
  b’	
  
5	
   TW	
  ‘hep	
  C’	
  
6	
   TW	
  Hbv	
  
7	
   TW	
  Chb	
  
8	
   TW	
  HCV	
  
9	
   TW	
  CHC	
  
10	
   1	
  OR	
  2	
  OR	
  3	
  OR	
  4	
  OR	
  5	
  OR	
  6	
  OR	
  7	
  OR	
  8	
  OR	
  9	
  
PWID	
  filter	
   	
  
11	
   (MM	
  "Substance	
  Abuse,	
  Intravenous")	
  
12	
   (MM	
  "Intravenous	
  Drug	
  Users")	
  
13	
   [TX]	
  drug	
  OR	
  [TX]	
  substance	
  OR	
  [TX]	
  cocaine[tw]	
  OR	
  [TX]	
  opioid*	
  OR	
  [TX]	
  opiate*	
  
OR	
  [TX]	
  methadone	
  OR	
  [TX]	
  narcotic*	
  OR	
  [TX]	
  PWID	
  OR	
  [TX]	
  psychostimulant*	
  
OR	
  [TX]	
  crack	
  OR	
  [TX]	
  IDU	
  or	
  [TX]	
  morphine	
  OR	
  [TX]	
  narcotic*	
  
14	
   [TX]	
  addict*	
  OR	
  [TX]	
  abus*	
  OR	
  [TX]	
  user*	
  OR	
  [TX]	
  inject*	
  	
  OR	
  [TX]	
  dependen*	
  OR	
  
[TX]	
  disorder*	
  OR	
  [TX]	
  overdose	
  
 
	
  
18	
  
15	
   13	
  AND	
  14	
  
16	
   11	
  OR	
  12	
  OR	
  15	
  
Filter	
  for	
  	
  intervention	
   	
  
17	
   	
  MH	
  "Psychotherapy+"	
  
18	
   	
  (MM	
  "Peer	
  Group")	
  	
  
19	
   (MH	
  "Counseling+")	
  
20	
   [TW]peer*	
  OR	
  [TW]	
  Motivation*	
  OR	
  [TW]"minimal	
  intervention"	
  OR	
  [TW]"brief	
  
intervention"	
  OR	
  [TW]testing	
  OR	
  [TW]psychosocial	
  or	
  [tw]advice	
  OR	
  
[TW]counseling	
  
21	
   17	
  OR	
  18	
  OR	
  19	
  OR	
  20	
  
22	
   10	
  AND	
  16	
  AND	
  21	
  
	
  
	
  
Search	
  strategy	
  for	
  WHO	
  regional	
  databases	
  
Date:	
  October	
  2010	
  
#	
   Searches	
  
LILACS	
   (	
  (	
  (	
  (	
  "HEPATITIS	
  B"	
  )	
  or	
  "HEPATITIS	
  B,	
  chronic"	
  )	
  or	
  "HEPATITIS	
  C"	
  )	
  or	
  "hepatitis	
  
c,	
  chronic"	
  )	
  or	
  "HEPACIVIRUS"	
  [Subject	
  descriptor]	
  or	
  "CHC"	
  or	
  "HCV"	
  or	
  
"HEPATITIS	
  B"	
  or	
  "HEPATITIS	
  C"	
  or	
  "HBV"	
  or	
  "CHB"	
  [Words]	
  and	
  (	
  (	
  (	
  "SEROLOGIC	
  
TESTS"	
  )	
  or	
  "DIAGNOSTIC	
  TESTs,	
  routine"	
  )	
  or	
  "HEPATITIS	
  ANTIGENS"	
  )	
  or	
  
"HEPATITIS	
  ANTIBODIES"	
  [Subject	
  descriptor]	
  
African	
  Index	
  Medicus	
  
Index	
  Medicus	
  for	
  the	
  
Eastern	
  
Mediterranean	
  Region	
  
(Hepatitis	
  or	
  Hep*)	
  	
  
	
  
	
  
	
  
	
   	
  
 
	
  
19	
  
© World Health Organization 2012
All rights reserved. Publications of the World Health Organization are available on the WHO web site
(www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia,
1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail:
bookorders@who.int).
Requests for permission to reproduce or translate WHO publications – whether for sale or for
noncommercial distribution – should be addressed to WHO Press through the WHO web site
(http://www.who.int/about/licensing/copyright_form/en/index.html).
The designations employed and the presentation of the material in this publication do not imply the
expression of any opinion whatsoever on the part of the World Health Organization concerning the legal
status of any country, territory, city or area or of its authorities, or concerning the delimitation of its
frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may
not yet be full agreement.
The mention of specific companies or of certain manufacturers’ products does not imply that they are
endorsed or recommended by the World Health Organization in preference to others of a similar nature
that are not mentioned. Errors and omissions excepted, the names of proprietary products are
distinguished by initial capital letters.
All reasonable precautions have been taken by the World Health Organization to verify the information
contained in this publication. However, the published material is being distributed without warranty of
any kind, either expressed or implied. The responsibility for the interpretation and use of the material
lies with the reader. In no event shall the World Health Organization be liable for damages arising from
its use.
	
  
	
  
	
  
	
  

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Who hiv 2012.28_eng

  • 1.     WHO/HIV/2012.28   Annex  7:    Search  Strategies     General  Procedures  (Applicable  to  all  PICO  Questions)   The  researchers  searched  the  following  electronic  databases  the  date  ranges  used  varied  by   question:     PubMed,  PsycINFO,  Sociological  Abstracts,  the  Cochrane  Central  Database  of  Systematic  Reviews,   CINAHL  (Cumulative  Index  to  Nursing  and  Allied  Health  Literature),  and  EMBASE   For  the  serosorting  question,  hand  searching  in  the  following  journals  was  also  conducted  for  years   1990-­‐2009:  AIDS,  JAIDS,  AIDS  and  Behaviour,  AIDS  Education  and  Prevention,  and  AIDS  Care.   For  the  sex  venue,  internet-­‐based,  and  social  marketing  interventions  the  following  databases  were   also  used:  LILACS  (Latin  America  and  Brasil),  Web  of  Science  /  Web  of  Social  Science,  China  National   Knowledge  Infrastructure  (CNKI),  CQ  VIP  (China)     Medical  subject  headings  (MeSH)  were  used  in  addition  to  key  words  to  maximize  sensitivity  and   specificity  of  searches.       MeSH  terms  and  keywords  were  PICO  question-­‐specific  (see  below  for  terms  used).     Secondary  reference  searching  was  also  conducted  on  all  articles  included  in  the  review  as  well  as  in   past  systematic  reviews  and  meta-­‐analyses.     Conferences  searched  included:   International  AIDS  Conference   Conference  on  HIV  Pathogenesis,  Treatment,  and  Prevention   Conference  on  Retroviruses  and  Opportunistic  Infections   For  the  sex  venue,  internet-­‐based,  and  social  marketing  interventions  the  following  databases  were   also  used:  British  HIV/AIDS  Association,  2001-­‐2008,  Conference  on  Retroviruses  and  Opportunistic   Infections  (CROI),  1994-­‐2008,  European  AIDS  Society  Conference,  2001  and  2003,  International  AIDS   Society,  International  AIDS  Conference  (IAC),  1994-­‐2004,  International  AIDS  Society,  Conference  on   HIV  Pathogenesis,  Treatment  and  Prevention  (IAS),  2001-­‐2005,  US  National  HIV  Prevention   Conference,  1999,  2003,  and  2005  as  well  as  CROI  and  International  AIDS  Society  web  sites  for   abstracts  presented  at  conferences  subsequent  to  those  listed  above  (CROI,  2009-­‐2010;  IAC,  2006-­‐ 2010;  IAS,  2007-­‐2009).     Articles  and  citations  were  downloaded,  organized,  and  reviewed.      
  • 2.     2     Inclusion  criteria   To  be  included  in  the  systematic  review  and  GRADEing  processes,  an  article  meet  the  following   criteria:   Published  in  a  peer-­‐reviewed  journal,  or  presented  as  an  abstract  at  a  scientific  conference  only  if   additional  information  could  be  gleaned  from  the  author.   Include  information  that  is  pertinent  to  at  least  1  PICO  question  of  interest.     Screening  abstracts   Two  independent  reviewers  screened  the  titles  and  abstracts  of  citations  identified  through  the   search  strategy  for  potential  eligibility.    Full  text  articles  were  obtained  for  all  selected  abstracts;   each  article  was  reviewed  by  two  independent  reviewers  to  determine  eligibility  given  the  above   inclusion  criteria.  Differences  between  the  two  reviewers  were  discussed  and  resolved  through   consensus.         Data  extraction  and  management   Data  were  extracted  by  two  reviewers  using  standardized  data  extraction  spreadsheets.  Differences   in  data  extraction  will  be  resolved  through  consensus.  The  following  information  was  gathered  from   each  included  study:   Study  identification;  author(s);  type  of  citation;  year  of  publication   Study  description:  Location,  setting  &  target  group;  years  (period  of  study);  description  of  the   intervention;  comparison  groups;  study  design;  sample  size;  age  range,  gender;  random  or  non-­‐ random  allocation  of  participants;  length  of  follow-­‐up  (all  if  applicable)   Outcomes  and  results:  Outcome  measures;  effect  sizes;  confidence  intervals;  significance  levels   Other  information:  limitations;  references  for  follow-­‐up;  secondary  effects/adverse  effects     Search  terms  by  PICO  question     Questions  1  and  2    
  • 3.     3   Search  strategy  for  The  Cochrane  Library   Date:  February  2011   Hepatitis  C    &  B     Searches   1   MeSH  descriptor  Hepatitis  B  explode  all  trees   2   MeSH  descriptor  Hepatitis  B  virus  explode  all  trees   3   Hbv:ti,ab   4   Chb:ti,ab   5   MeSH  descriptor  Hepacivirus  explode  all  trees   6   MeSH  descriptor  Hepatitis  C  explode  all  trees   7   Hepatitis:ab,ti   8   HCV.ti,ab,kw   9   CHC:ti,ab   10   #1  OR  #2  OR  #3  OR  #4  OR  #5  OR  #6  OR  #7  OR  #8  OR  #9     PWID  filter     11   MeSH  descriptor  Substance-­‐related  disorder  explode  all  trees   12   Drug:ti,ab,kw  OR  substance:ti,ab,kw  OR  heroin:ti,ab,kw  OR  cocaine:ti,ab,kw  OR   opioid*:ti,ab,kw  OR  opiate*:ti,ab,kw  or  methadone:ti,ab,kw  OR  narcotic*:ti,ab,kw  OR   PWID:ti,ab,kw  OR  psychostimulant*:ti,ab,kw  or  crack:ti,ab,kw  or  IDU:ti,ab,kw    OR   morphine:  ti,ab,kw       13   addict*:ti,ab  OR  abus*:ti,ab  OR  user*:ti,ab  OR  inject*:ti,ab    OR  dependen*:ti,ab  or   disorder*:ti,ab    OR  overdos*:ti,ab   14   #12  AND  #13   15   #11  OR  #14   Vaccination   filter     16   "Immunization"[Mesh]   17   Immunization:ti,ab  or  vaccinat*:ti,ab  OR  immunisation:ti,ab  OR  immunotherapy[tiab]       18   MeSH  descriptor  Immunization  Programs  explode  all  trees         19   #16  OR  #17  OR  #18  
  • 4.     4   Filter  for   intervention     20   incentive*:ti,ab  OR  voucher*:ti,ab  OR  contingen*:ti,ab  or  money:ti,ab     Motivation*:ti,ab  OR  inducement[tiab]  OR  reward[tiab]  OR  prize  [tiab]   21   MeSH  descriptor  "Reimbursement,  Incentive"  explode  all  trees   22   #20  OR  #21     23   #10  AND  #15  AND  #19     24   #10  AND  #15  AND  #19  AND  #23       Search  strategy  for  PubMed:   Date:  February  2011   #   Searches   Hepatitis  C  filter:     1   Hepatitis  C[Mesh]   2   Hepatitis  C,  Chronic[Mesh]   3   "hep  C"[tiab]   4   HCV[All  Fields]   5   "HCV-­‐DNA"[All  Fields]   6   "CHC"[All  Fields]   7   hepatitis[tiab]   8   Hepacivirus[MESH]   Hepatitis  B  filter:     9   "Hepatitis  B"[MeSH  Terms]   10   "Hepatitis  B,  Chronic"[MeSH  Terms]   11   "hep  B”[tiab]   12   HBV[tiab]   13   "HBV-­‐DNA"[tiab]  
  • 5.     5   14   CHB[tiab]   15   #1  OR  #2  OR  #3  OR  #4  OR  #5  OR  #6  OR  #7  OR  #8  OR  #9  OR  #10  OR  #11  or  #12  or   #13  or  #14   PWID  filter     16   Substance-­‐related  disorder[mesh]   17   addict*[tiab]  OR  abuse[tiab]  OR  user*[tiab]  OR  inject*[tiab]  OR  dependen*[tiab]   or  disorder*[tiab]  or  overdos*[tiab]   18   drug  [tw]  OR  alcohol  [tw]  OR  substance  [tw]  OR  amphetamine*[tw]  OR   cocaine[tw]  OR  opioid*[tw]  OR  opiate*[tw]  or  methadone[tw]  OR  narcotic*[tw]   OR  PWID[tw]  OR  psychostimulant*[tw]  or  crack[tiab]  or  IDU[tiab]  or  morphine   [tiab]   19   #18  AND  #17   20   #16  OR  #19   Vaccination  filter     21   "Immunization"[Mesh]   22   "Immunization  Programs"[Mesh]   23   Immunization[tiab]  or  vaccinat*[tiab]  OR  immunisation[tiab]  or   immunotherapy[tiab]   24   #21  OR  #22  OR  #23   Filter  for  intervention     25   incentive*[TIAB]  OR  voucher*[tiab]  OR  contingen*[tiab]  or  money[tiab]   Motivation*[tiab]  OR  inducement[tiab]  OR  reward[tiab]  OR  prize  [tiab]   26   "Reimbursement,  Incentive"[Mesh]   27   #25  OR  #26     28   #15  AND  #20  AND  #24   29   #15  AND  #20  AND  #24  AND  #27   30   Animals[mesh]  NOT  humans[mesh]   31   #28  NOT  #30   32   #29  NOT  #30      
  • 6.     6   Search  strategy  for  EMBASE     Date:  February  2011   Hepatitis   filter     1   'hepatitis  c'/exp  OR  'hepatitis  c'  OR  'hep  c'  OR  'hcv'  OR  'chc'  OR  'hepatitis'/exp  OR   'hepatitis'  OR  'hepacivirus':ab,ti  OR  'hepatitis  b'/exp  OR  'hepatitis  b'  OR  'hep  b':ab,ti  OR   'hbv':ab,ti  OR  'chb':ab,ti  OR  'hepatitis  virus  non  a  non  b'/exp  OR  'hepatitis  virus  non  a   non  b'  OR  'hepatitis  b  virus'/exp  OR  'hepatitis  b  virus'  OR  'hepatitis  c  virus'/exp  OR   'hepatitis  c  virus'  OR  'hepatitis  virus'/exp  OR  'hepatitis  virus'   PWID  filter     2   'drug  abuse'/exp  OR  'drug  abuse'  OR  addict*:ab,ti  OR  abuse:ab,ti  OR  user*:ab,ti  OR   inject*:ab,ti  OR  dependen*:ab,ti  OR  disorder*:ab,ti  AND  ('drug'/exp  OR  drug  OR   substance  OR  'cocaine'/exp  OR  cocaine  OR  opioid*  OR  opiate*  OR  'methadone'/exp  OR   methadone  OR  narcotic*  OR  pwid  OR  psychostimulant*  OR  crack:ab,ti  OR  idu:ab,ti  OR   morphine:  ab,ti  )   3        #1  AND  #2                                                             Vaccination   filter     4   Immunization:ti,ab  or  vaccinat*:ti,ab  OR  immunisation:ti,ab  OR  immunotherapy[tiab]   Filter  for   intervention     5   incentive*:ti,ab  OR  voucher*:ti,ab  OR  contingen*:ti,ab  or  money:ti,ab    Motivation*:ti,ab   OR  inducement:ti,ab  OR  reward:ti,ab  OR  prize:ti,ab  or  reimbursement:ti,ab   6   #3  AND  #4     7   #3  AND  #4  AND  #5       Search  strategy  for  CINAHL     Date:  February  2011   Hepatitis  filter   Searches   1   MH  Hepatitis  B     2   MH  Hepatitis  C  
  • 7.     7   3   TW  Hepatitis     4   TX  ‘hep  b’   5   TX  ‘hep  C’   6   TX  Hbv   7   TX  Chb   8   TX  HCV   9   TX  CHC   10   1  OR  2  OR  3  OR  4  OR  5  OR  6  OR  7  OR  8  OR  9   PWID  filter     11   (MM  "Substance  Abuse,  Intravenous")   12   (MM  "Intravenous  Drug  Users")   13   TX  drug  OR  TX  substance  OR  TX  cocaine  OR  TX  opioid*  OR  TX  opiate*  OR  TX  methadone   OR  TX  narcotic*  OR  TX  PWID  OR  TX  psychostimulant*  OR  TX  crack  OR  TX  IDU  or  TX   morphine  OR  TX  narcotic*   14   TX  addict*  OR  TX  abus*  OR  TX  user*  OR  TX  inject*    OR  TX  dependen*  OR  TX  disorder*   OR  TX  overdose   15   13  AND  14   16   11  OR  12  OR  15   Vaccination   filter     17   (MH  "Immunization+")   18   TX  Immunization  or  TX  vaccinat*  OR  TX  immunisation  OR  TX  immunotherapy   19   17  OR  18   Filter  for   intervention     20   TX  incentive*  OR  TX  voucher*  OR  TX  contingen*  or  TX  money    TX  Motivation*  OR  TX   inducement  OR  TX  reward:ti,ab  TX  prize  or  TX  reimbursement   21   10  AND  16  AND  19   22   10  AND  16  AND  19  AND  20      
  • 8.     8   Search  strategy  for  WHO  regional  databases   Date:  October  2010   #   Searches   LILACS   (  (  (  (  "HEPATITIS  B"  )  or  "HEPATITIS  B,  chronic"  )  or  "HEPATITIS  C"  )  or  "hepatitis   c,  chronic"  )  or  "HEPACIVIRUS"  [Subject  descriptor]  or  "CHC"  or  "HCV"  or   "HEPATITIS  B"  or  "HEPATITIS  C"  or  "HBV"  or  "CHB"  [Words]  and  (  (  (  "SEROLOGIC   TESTS"  )  or  "DIAGNOSTIC  TESTs,  routine"  )  or  "HEPATITIS  ANTIGENS"  )  or   "HEPATITIS  ANTIBODIES"  [Subject  descriptor]   African  Index  Medicus   Index  Medicus  for  the   Eastern   Mediterranean  Region   (Hepatitis  or  Hep*)       Question  3       Search  strategy  for  The  Cochrane  Library   Date:  September  2011   Hepatitis  C    &  B     Searches   1   MeSH  descriptor  Hepatitis  B  explode  all  trees   2   MeSH  descriptor  Hepatitis  B  virus  explode  all  trees   3   Hbv:ti,ab   4   Chb:ti,ab   5   MeSH  descriptor  Hepacivirus  explode  all  trees   6   MeSH  descriptor  Hepatitis  C  explode  all  trees   7   Hepatitis:ab,ti   8   HCV.ti,ab,kw   9   CHC:ti,ab   10   #1  OR  #2  OR  #3  OR  #4  OR  #5  OR  #6  OR  #7  OR  #8  OR  #9     HIV    
  • 9.     9   11   MeSH  descriptor  HIV  Infections  explode  all  trees   12   MeSH  descriptor  HIV  explode  all  trees   13   HIV   14   MeSH  descriptor  Acquired  Immunodeficiency  Syndrome  explode  all  trees   15   #11  OR  #12  OR  #13  OR  #14   PWID  filter     16   MeSH  descriptor  Substance-­‐related  disorder  explode  all  trees   17   Drug:ti,ab,kw  OR  substance:ti,ab,kw  OR  heroin:ti,ab,kw  OR  cocaine:ti,ab,kw  OR   opioid*:ti,ab,kw  OR  opiate*:ti,ab,kw  or  methadone:ti,ab,kw  OR  narcotic*:ti,ab,kw  OR   PWID:ti,ab,kw  OR  psychostimulant*:ti,ab,kw  or  crack:ti,ab,kw  or  IDU:ti,ab,kw    OR   morphine:  ti,ab,kw       18   addict*:ti,ab  OR  abus*:ti,ab  OR  user*:ti,ab  OR  inject*:ti,ab    OR  dependen*:ti,ab  or   disorder*:ti,ab    OR  overdos*:ti,ab   19   #17  AND  #18   20   #16  OR  #19   Dead-­‐Space   Syringes     21   MeSH  descriptor  Syringes  explode  all  trees   22   MeSH  descriptor  Needle  Sharing  explode  all  trees   23     syringe  next  type   24   (dead  AND  space  AND  syringe*)   25   #21  OR  #22  OR  #23  OR  #24   26   #10  OR  #15   27   #20  AND  #25  AND  #26       Search  strategy  for  PubMed:   Date:  September  2011   #   Searches  
  • 10.     10   Hepatitis  C  filter:     1   Hepatitis  C[Mesh]   2   Hepatitis  C,  Chronic[Mesh]   3   "hep  C"[tiab]   4   HCV[All  Fields]   5   "HCV-­‐DNA"[All  Fields]   6   "CHC"[All  Fields]   7   hepatitis[tiab]   8   Hepacivirus[MESH]   Hepatitis  B  filter:     9   "Hepatitis  B"[MeSH  Terms]   10   "Hepatitis  B,  Chronic"[MeSH  Terms]   11   "hep  B”[tiab]   12   HBV[tiab]   13   "HBV-­‐DNA"[tiab]   14   CHB[tiab]   HIV     15   HIV  Infections[MeSH]  OR  HIV[MeSH]  OR  hiv[tw]  OR  hiv1[tw]  OR  hiv2[tw]  OR  human   immunodeficiency  virus[tw]  OR  human  immunedeficiency  virus[tw]  OR  ((human  immun*)   AND(deficiency  virus[tw]))OR  acquired  immunodeficiency  syndrome[tw]OR  acquired   immunedeficiency  syndrome[tw]OR  acquired  immuno-­‐deficiency  syndrome[tw]  OR   acquired  immune-­‐deficiency  syndrome[tw]  OR  ((acquired  immun*)  AND  (deficiency   syndrome[tw])  )   16   #1  OR  #2  OR  #3  OR  #4  OR  #5  OR  #6  OR  #7  OR  #8  OR  #9  OR  #10  OR  #11  OR  #12   OR  #13  OR  #14  OR  #15   PWID  filter     17   Substance-­‐related  disorder[mesh]   18   addict*[tiab]  OR  abuse[tiab]  OR  user*[tiab]  OR  inject*[tiab]  OR  dependen*[tiab]   or  disorder*[tiab]  or  overdos*[tiab]   19   drug  [tw]  OR  alcohol  [tw]  OR  substance  [tw]  OR  amphetamine*[tw]  OR   cocaine[tw]  OR  opioid*[tw]  OR  opiate*[tw]  or  methadone[tw]  OR  narcotic*[tw]   OR  PWID[tw]  OR  psychostimulant*[tw]  or  crack[tiab]  or  IDU[tiab]  or  morphine  
  • 11.     11   [tiab]   20   #18  AND  #19   21   #17  OR  #20   Dead-­‐Space  Syringes     22   "Syringes"[Mesh]   23   "Needle  Sharing"[Mesh]   24   (dead  AND  space  AND  syringe*)   25   LDSS[tiab]  OR  hdss[tiab]   26   #22  OR  #23  OR  #24  OR  #25   27   #16  AND  #21  AND  #26       Search  strategy  for  EMBASE     Date:  September  2011   Hepatitis   filter     1   'hepatitis  c'/exp  OR  'hepatitis  c'  OR  'hep  c'  OR  'hcv'  OR  'chc'  OR  'hepatitis'/exp  OR   'hepatitis'  OR  'hepacivirus':ab,ti  OR  'hepatitis  b'/exp  OR  'hepatitis  b'  OR  'hep  b':ab,ti  OR   'hbv':ab,ti  OR  'chb':ab,ti  OR  'hepatitis  virus  non  a  non  b'/exp  OR  'hepatitis  virus  non  a   non  b'  OR  'hepatitis  b  virus'/exp  OR  'hepatitis  b  virus'  OR  'hepatitis  c  virus'/exp  OR   'hepatitis  c  virus'  OR  'hepatitis  virus'/exp  OR  'hepatitis  virus'   HIV  filter     2   'human  immunodeficiency  virus  infection'/exp  OR  'hiv':ab,ti  OR  'human   immunodeficiency  virus':ab,ti  OR  'human  immuno-­‐deficiency  virus':ab,ti  OR  'human   immune-­‐deficiency  virus':ab,ti  OR  'acquired  immune-­‐deficiency  syndrome':ab,ti  OR   'acquired  immunedeficiency  syndrome':ab,ti  OR  'acquired  immuno-­‐deficiency   syndrome':ab,ti  AND  [embase]/lim   3   #1  OR  #2   PWID  filter     4   'drug  abuse'/exp  OR  'drug  abuse'  OR  addict*:ab,ti  OR  abuse:ab,ti  OR  user*:ab,ti  OR   inject*:ab,ti  OR  dependen*:ab,ti  OR  disorder*:ab,ti  AND  ('drug'/exp  OR  drug  OR   substance  OR  'cocaine'/exp  OR  cocaine  OR  opioid*  OR  opiate*  OR  'methadone'/exp  OR   methadone  OR  narcotic*  OR  pwid  OR  psychostimulant*  OR  crack:ab,ti  OR  idu:ab,ti  OR  
  • 12.     12   morphine:  ab,ti  )   5        #3  AND  #4                                                             Dead-­‐Space   Syringes     6   'syringe'/exp  OR  'syringe'   7   'needle  sharing':ab,ti   8   dead:ab,ti  AND  space:ab,ti  AND  syringe*:ab,ti   9   'ldss':ab,ti  OR  'hdss':ab,ti   10   #6  OR  #7  OR  #8  OR  #9   11   #5  AND  #10       Search  strategy  for  CINAHL     Date:  September  2011   Hepatitis  filter   Searches   1   MH  Hepatitis  B     2   MH  Hepatitis  C   3   TW  Hepatitis     4   TX  ‘hep  b’   5   TX  ‘hep  C’   6   TX  Hbv   7   TX  Chb   8   TX  HCV   9   TX  CHC   10   1  OR  2  OR  3  OR  4  OR  5  OR  6  OR  7  OR  8  OR  9   Hiv  filter     11   (MH  "HIV  Infections+")   12   (MH  "Human  Immunodeficiency  Virus+")  
  • 13.     13   13   (MH  "Acquired  Immunodeficiency  Syndrome")   14   TX  HIV   15   11  OR  12  OR  13  OR  14     16   10  OR  15   PWID  filter     17   (MM  "Substance  Abuse,  Intravenous")   18   (MM  "Intravenous  Drug  Users")   19   TX  drug  OR  TX  substance  OR  TX  cocaine  OR  TX  opioid*  OR  TX  opiate*  OR  TX  methadone   OR  TX  narcotic*  OR  TX  PWID  OR  TX  psychostimulant*  OR  TX  crack  OR  TX  IDU  or  TX   morphine  OR  TX  narcotic*   20   TX  addict*  OR  TX  abus*  OR  TX  user*  OR  TX  inject*    OR  TX  dependen*  OR  TX  disorder*   OR  TX  overdose   21   19  AND  20   22   17  OR  18OR  21   Dead-­‐Space   Syringes     23   (MH  "Syringes")   24   (MH  "Needle  Sharing")   25   (dead  AND  space  AND  syringe*)   26   TI  LDSS  OR  AB  LDSS  OR  TI  HDSS  OR  AB  HDSS   27   23  OR  24  OR  25  OR  26   28   16  AND  22  AND  26       Questions  4  and  5       Search  strategy  for  The  Cochrane  Library   Date:  February  2011  
  • 14.     14   Hepatitis  C    &  B     Searches   1   MeSH  descriptor  Hepatitis  B  explode  all  trees   2   MeSH  descriptor  Hepatitis  B  virus  explode  all  trees   3   Hbv:ti,ab   4   Chb:ti,ab   5   MeSH  descriptor  Hepacivirus  explode  all  trees   6   MeSH  descriptor  Hepatitis  C  explode  all  trees   7   Hepatitis:ab,ti   8   HCV.ti,ab,kw   9   CHC:ti,ab   10   #1  OR  #2  OR  #3  OR  #4  OR  #5  OR  #6  OR  #7  OR  #8  OR  #9     PWID  filter     11   MeSH  descriptor  Substance-­‐related  disorder  explode  all  trees   12   Drug:ti,ab,kw  OR  substance:ti,ab,kw  OR  heroin:ti,ab,kw  OR  cocaine:ti,ab,kw  OR   opioid*:ti,ab,kw  OR  opiate*:ti,ab,kw  or  methadone:ti,ab,kw  OR  narcotic*:ti,ab,kw  OR   PWID:ti,ab,kw  OR  psychostimulant*:ti,ab,kw  or  crack:ti,ab,kw  or  IDU:ti,ab,kw    OR   morphine:  ti,ab,kw       13   addict*:ti,ab  OR  abus*:ti,ab  OR  user*:ti,ab  OR  inject*:ti,ab    OR  dependen*:ti,ab  or   disorder*:ti,ab    OR  overdos*:ti,ab   14   #12  AND  #13   15   #11  OR  #14   Filter  for     intervention     16   MeSH  descriptor  "Psychotherapy,  Brief"  explode  all  trees   17   MeSH  descriptor  "Peer  Group"  explode  all  trees   18   peer*:ti,ab  OR  "peer  support":ti,ab  OR  motivation*:ti,ab  OR  "minimal   intervention":ti,ab  OR  "brief  intervention":ti,ab  OR  testing:ti,ab  OR  psychosocial:ti,ab   OR  adivice:ti,ab  OR  counseling:ti,ab   19   #16  OR  #17  OR  #18   20   #10  AND  #15  AND  #19      
  • 15.     15     Search  strategy  for  PubMed     Date:  February  2011   #   Searches   Hepatitis  C   filter:     1   Hepatitis  C[Mesh]   2   Hepatitis  C,  Chronic[Mesh]   3   "hep  C"[tiab]   4   HCV[All  Fields]   5   "HCV-­‐DNA"[All  Fields]   6   "CHC"[All  Fields]   7   hepatitis[tiab]   8   Hepacivirus[MESH]   Hepatitis  B   filter:     9   "Hepatitis  B"[MeSH  Terms]   10   "Hepatitis  B,  Chronic"[MeSH  Terms]   11   "hep  B”[tiab]   12   HBV[tiab]   13   "HBV-­‐DNA"[tiab]   14   CHB[tiab]   15   #1  OR  #2  OR  #3  OR  #4  OR  #5  OR  #6  OR  #7  OR  #8  OR  #9  OR  #10  OR  #11  or  #12  OR  #13  OR   #14   PWID  filter     16   drug  [tw]  OR  substance  [tw]  OR  cocaine[tw]  OR  opioid*[tw]  OR  opiate*[tw]  or   methadone[tw]  OR  narcotic*[tw]  OR  PWID[tw]  OR  psychostimulant*[tw]  OR  crack[tiab]   OR  IDU[tiab]  or  morphine[tw]   17   addict*[tiab]  OR  abuse[tiab]  OR  user*[tiab]  OR  inject*[tiab]  OR  dependen*[tiab]  or   disorder*[tiab]  OR  overdos*[tiab]  
  • 16.     16   18   16  AND  17   19   Substance-­‐related  disorder[mesh]   20   #18  OR  #19   21   #15  AND  #20   Filter  for   intervention     22   "Psychotherapy,  Brief"[Mesh]   23   Counseling[mesh]   24   "Peer  Group"[Mesh]   25   advice[tiab]  OR  peer*[tiab]  OR  "peer  support"  [tiab]  OR  "Brief  intervention"  [tiab]  OR     "minimal  intervention"[tiab]  OR  motivation[tiab]  OR  psychosocial[tiab]  OR   counseling[tiab]  OR  test*[tiab]  OR  testing[tiab]     26   #22  OR  #23  OR  #24  OR  #25   27   #26  AND  #21   28   Animals[mesh]  NOT  humans[mesh]   29   #27  NOT  #28         Search  strategy  for  EMBASE     Date:  February  2011   Hepatitis  filter:     1   'hepatitis  c'/exp  OR  'hepatitis  c'  OR  'hep  c'  OR  'hcv'  OR  'chc'  OR  'hepatitis'/exp  OR   'hepatitis'  OR  'hepacivirus':ab,ti  OR  'hepatitis  b'/exp  OR  'hepatitis  b'  OR  'hep  b':ab,ti  OR   'hbv':ab,ti  OR  'chb':ab,ti  OR  'hepatitis  virus  non  a  non  b'/exp  OR  'hepatitis  virus  non  a   non  b'  OR  'hepatitis  b  virus'/exp  OR  'hepatitis  b  virus'  OR  'hepatitis  c  virus'/exp  OR   'hepatitis  c  virus'  OR  'hepatitis  virus'/exp  OR  'hepatitis  virus'   PWID  filter     2   'drug  abuse'/exp  OR  'drug  abuse'  OR  addict*:ab,ti  OR  abuse:ab,ti  OR  user*:ab,ti  OR   inject*:ab,ti  OR  dependen*:ab,ti  OR  disorder*:ab,ti  AND  ('drug'/exp  OR  drug  OR   substance  OR  'cocaine'/exp  OR  cocaine  OR  opioid*  OR  opiate*  OR  'methadone'/exp  OR   methadone  OR  narcotic*  OR  pwid  OR  psychostimulant*  OR  crack:ab,ti  OR  idu:ab,ti  OR   morphine:  ab,ti  )  
  • 17.     17   3        #1  AND  #2                                                             Filter  for   intervention     4   psychosocial*:ab,ti  OR  counseling:ab,ti  OR  advice:  ab,ti  OR  reinforcement:  ab,ti    OR   motivation*:  ab,ti  OR  education:  ab,ti  OR  psychotherapy:ab,ti  OR  social:ab,ti  OR   peer:ab,ti  or  brief  intervention:  ab,ti  OR  testing:ab,ti  or  test:ab,ti       Search  strategy  for  CINAHL     Date:  February  2011   #   Searches   Hepatitis  filter     1   MH  Hepatitis  B     2   MH  Hepatitis  C   3   TW  Hepatitis     4   TW  ‘hep  b’   5   TW  ‘hep  C’   6   TW  Hbv   7   TW  Chb   8   TW  HCV   9   TW  CHC   10   1  OR  2  OR  3  OR  4  OR  5  OR  6  OR  7  OR  8  OR  9   PWID  filter     11   (MM  "Substance  Abuse,  Intravenous")   12   (MM  "Intravenous  Drug  Users")   13   [TX]  drug  OR  [TX]  substance  OR  [TX]  cocaine[tw]  OR  [TX]  opioid*  OR  [TX]  opiate*   OR  [TX]  methadone  OR  [TX]  narcotic*  OR  [TX]  PWID  OR  [TX]  psychostimulant*   OR  [TX]  crack  OR  [TX]  IDU  or  [TX]  morphine  OR  [TX]  narcotic*   14   [TX]  addict*  OR  [TX]  abus*  OR  [TX]  user*  OR  [TX]  inject*    OR  [TX]  dependen*  OR   [TX]  disorder*  OR  [TX]  overdose  
  • 18.     18   15   13  AND  14   16   11  OR  12  OR  15   Filter  for    intervention     17    MH  "Psychotherapy+"   18    (MM  "Peer  Group")     19   (MH  "Counseling+")   20   [TW]peer*  OR  [TW]  Motivation*  OR  [TW]"minimal  intervention"  OR  [TW]"brief   intervention"  OR  [TW]testing  OR  [TW]psychosocial  or  [tw]advice  OR   [TW]counseling   21   17  OR  18  OR  19  OR  20   22   10  AND  16  AND  21       Search  strategy  for  WHO  regional  databases   Date:  October  2010   #   Searches   LILACS   (  (  (  (  "HEPATITIS  B"  )  or  "HEPATITIS  B,  chronic"  )  or  "HEPATITIS  C"  )  or  "hepatitis   c,  chronic"  )  or  "HEPACIVIRUS"  [Subject  descriptor]  or  "CHC"  or  "HCV"  or   "HEPATITIS  B"  or  "HEPATITIS  C"  or  "HBV"  or  "CHB"  [Words]  and  (  (  (  "SEROLOGIC   TESTS"  )  or  "DIAGNOSTIC  TESTs,  routine"  )  or  "HEPATITIS  ANTIGENS"  )  or   "HEPATITIS  ANTIBODIES"  [Subject  descriptor]   African  Index  Medicus   Index  Medicus  for  the   Eastern   Mediterranean  Region   (Hepatitis  or  Hep*)              
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