Rinkodaros automatizavimas 30 robotų sprendimų automatizuoti rinkodarą ir besikartojantį darbą sprendimai. Pagal Jūsų specialių poreikį gali būti sukurti Jums reikalingi. Įjunkite kompiuterį atėję į darbą ir programos atliks visą Jums reikalingą darbą. Interneto rinkodara gali būti efektyvi ir naudinga jeigu ji vykdoma aktyviai, išnaudojant kanalo visas suteikiamas srauto galimybes ir jei ji yra pigi naudoti. Jeigu smulkaus ir vidutinio verslo įmonės darbuotojai skirtų savo laiką reikalingiems skaitmeninės rinkodaros veiksmams ji tampa nuostolinga. Rinkodaros veiksmus ir biuro pasikartojančius darbus internete galima automatizuoti su nemokamomis rinkodaros programų versijomis ir naršyklių darbo automatizavimo programomis. Jūsų biuro kompiuteris su integruotais sprendimais gali tapti nauju biuro darbuotoju atliekančiu interneto rinkodaros veiksmus ir rutinos darbus interneto svetainėse ir debesų technologijų programose. Kiekvienam pagal poreikius galima įdiegti programas, jas papildyti programų funkcijomis, kurios yra reikalingos specialiems interneto darbams ir užduotims, integruoti programas kad nustatytų laiku ir pasikartojančiais intervalais atliktų reikalingas užduotis. Programas robotus galima panaudoti rinkodaros tyrimams ir informacijos surinkimui. Programos robotai gali būti panaudojamos surenkant informaciją apie prekių kainas, populiariausius prekių modelius, žmonių nuomonių informacijos surinkimui socialiniuose tinklapiuose apie konkrečias prekes, elektroninio pašto adresus tiesioginei
3 pagrindinės priežastys, kodėl Jūsų verslas dabar turi naudoti Pinterest. Kodėl reikia naudoti Pinterest Verslo paskyrą, o ne asmeninę paskyrą? Šiame straipsnyje aprašytos 5 idėjas, kaip padaryti populiarius, bendrinamus Pin'us; kaip pradėti, gauti rasti ir gauti pasekėjų Pinterest'e.
Google tyrimų darbuotojai planuoja įvesti svetainių rangų sistemą, kuri remsis juose aprašomais faktais, o ne jas siejančiomis nuorodomis
Ar "Google" vieną dieną reitinguos svetaines remiantis, kas jose tiksliai aprašoma? Naujausi duomenys rodo, kad gali taip atsitikti. Užmerkite akis ir įsivaizduoti pasaulį, kuriame tinklalapius reitinguoja ne tik populiarumas - ty, nuorodos, kurios nurodo į jas, o taip pat ant kiek tiksli yra jose informacija. Tad pasaulis nebus nutolęs.
Rinkodaros automatizavimas 30 robotų sprendimų automatizuoti rinkodarą ir besikartojantį darbą sprendimai. Pagal Jūsų specialių poreikį gali būti sukurti Jums reikalingi. Įjunkite kompiuterį atėję į darbą ir programos atliks visą Jums reikalingą darbą. Interneto rinkodara gali būti efektyvi ir naudinga jeigu ji vykdoma aktyviai, išnaudojant kanalo visas suteikiamas srauto galimybes ir jei ji yra pigi naudoti. Jeigu smulkaus ir vidutinio verslo įmonės darbuotojai skirtų savo laiką reikalingiems skaitmeninės rinkodaros veiksmams ji tampa nuostolinga. Rinkodaros veiksmus ir biuro pasikartojančius darbus internete galima automatizuoti su nemokamomis rinkodaros programų versijomis ir naršyklių darbo automatizavimo programomis. Jūsų biuro kompiuteris su integruotais sprendimais gali tapti nauju biuro darbuotoju atliekančiu interneto rinkodaros veiksmus ir rutinos darbus interneto svetainėse ir debesų technologijų programose. Kiekvienam pagal poreikius galima įdiegti programas, jas papildyti programų funkcijomis, kurios yra reikalingos specialiems interneto darbams ir užduotims, integruoti programas kad nustatytų laiku ir pasikartojančiais intervalais atliktų reikalingas užduotis. Programas robotus galima panaudoti rinkodaros tyrimams ir informacijos surinkimui. Programos robotai gali būti panaudojamos surenkant informaciją apie prekių kainas, populiariausius prekių modelius, žmonių nuomonių informacijos surinkimui socialiniuose tinklapiuose apie konkrečias prekes, elektroninio pašto adresus tiesioginei
3 pagrindinės priežastys, kodėl Jūsų verslas dabar turi naudoti Pinterest. Kodėl reikia naudoti Pinterest Verslo paskyrą, o ne asmeninę paskyrą? Šiame straipsnyje aprašytos 5 idėjas, kaip padaryti populiarius, bendrinamus Pin'us; kaip pradėti, gauti rasti ir gauti pasekėjų Pinterest'e.
Google tyrimų darbuotojai planuoja įvesti svetainių rangų sistemą, kuri remsis juose aprašomais faktais, o ne jas siejančiomis nuorodomis
Ar "Google" vieną dieną reitinguos svetaines remiantis, kas jose tiksliai aprašoma? Naujausi duomenys rodo, kad gali taip atsitikti. Užmerkite akis ir įsivaizduoti pasaulį, kuriame tinklalapius reitinguoja ne tik populiarumas - ty, nuorodos, kurios nurodo į jas, o taip pat ant kiek tiksli yra jose informacija. Tad pasaulis nebus nutolęs.
MORPHOLOGICAL STUDY OF THE MUSCLE- BONE INTERFACE IN MAN
The aim of the present study was to investigate the histological structure of the fleshy muscle-bone interface in selected limb muscles in man, as compared to that of the enthesis, in an attempt to clarify the way muscle fibers transmit their contractile force to adjacent bone. The muscle specimens were taken from biceps and tendocalcaneus as examples for the tendon-bone attachment (enthesis), from external intercostal, brachioradialis, and external oblique muscles as examples for the linear fleshy attachment, and from infraspinatus and brachialis as examples for the fleshy attachment over a wide area.
The muscle-bone interface specimens were collected form six formalin-fixed dissecting room elderly male cadavers with no gross pathology. The whole muscle-bone interface was extracted so that each specimen included the muscle and the underlying bone tissues. The specimens were fixed in 10% neutral buffered formol saline for one week, and then decalcified with 10% EDTA for about 4-6 weeks. Dehydrated in ascending grades of alcohols, cleared in xylol, and embedded in paraffin wax. Serial sections were cut at 8-µm thickness and stained with Haematoxylin and eosin, and Masson's trichrome.
In the present work, it was found that tendon-bone attachment of either biceps brachii or tendocalcaneus was formed of four zones; zone 1 (Z1) of dense connective tissue, zone 2 (Z2) of fibrocartilage, zone 3 (Z3) of calcified fibrocartilage, and zone 4 (Z4) of compact bone. Serrated basophilic line "tidemark" was usually seen between fibrocartilage and calcified fibrocartilage zones. Moreover, differences in the distribution and population of chondrocytes occurred between zone 2 (Z2) and zone 3 (Z3).
On the other hand, the muscle-bone interface of brachialis, infraspinatus, brachioradialis, and external intercostal muscles was noticed to be formed of three zones; zone 1 (Z1) of skeletal muscle tissue, zone 2 (Z2) of dense connective tissue, and zone 3 (Z3) of compact bone. The dense connective tissue zone interposed between the skeletal muscle fibers and the bone differed in its density and structure between the studied muscles. Moreover, some regions of the attachment site of the external oblique muscle were observed to include zones of fibrocartilage and calcified fibrocartilage so that a mixture of fibrocartilaginous and fibrous attachment could be identified.
From the above mentioned findings it was concluded that three patterns of muscle-bone interfaces could be described according to the number and types of histological zones; (1) the classical pattern of tendon-bone interface (enthesis) formed of the four zones, (2) the fleshy pattern of the muscle-bone interface characterized by absence of fibrocartilage, (3) the third pattern is an admixture of the previous two patterns. The present findings would be helpful in clinical practice; especially, for the choice of the suitable muscle for transplant.
The ameliorative potential of hyphaene thebaica on streptozotocin induced dia...Prof. Hesham N. Mustafa
Background: Diabetic nephropathy (DN) is the leading cause of end-stage renal
disease. The aim of the current study is to investigate the possible beneficial effects
of Hyphaene thebaica in DN.
Materials and methods: For this, 50 male albino rats were divided into five
groups: group I — represented the control group; group II — received Hyphaene thebaica extracts of 150 mg/kg BW by oral gavage for 6 weeks; group III
— received single intraperitoneal injections of streptozotocin (50 mg/kg BW)
to induce type-2 diabetes mellitus; group IV (protective) — diabetic rats received Hyphaene thebaica extract (150 mg/kg BW) orally for 6 weeks; group V
(curative) — received Hyphaene thebaica extract (150 mg/kg BW) orally after the
diagnosis of DN.
Results: In the DN protected group, blood glucose, urea, and creatinine decreased
significantly, while insulin and C-peptide increased significantly. Moreover, cystatin C
and neutrophil gelatinase-associated lipocalin decreased. Collagen fibre deposition is increased with an apparent thickening of the parietal layer of Bowman’s
capsules and the basal lamina of convoluted tubules, as well as increase of the
immune-reaction of caspase-3 and desmin. The introduction of Hyphaene thebaica
led to greater amelioration in the biochemical markers, apoptotic alterations, and
podocyte injuries of the protected group than in the curative group.
Conclusions: Hyphaene thebaica may be advised as a good choice that can delay
diabetic renal complications. (Folia Morphol 2015; 74, 4: 447–457)
Key words: diabetic nephropathy, Hyphaene thebaica, podocyte injury,
apoptosis
MORPHOLOGICAL STUDY OF THE MUSCLE- BONE INTERFACE IN MAN
The aim of the present study was to investigate the histological structure of the fleshy muscle-bone interface in selected limb muscles in man, as compared to that of the enthesis, in an attempt to clarify the way muscle fibers transmit their contractile force to adjacent bone. The muscle specimens were taken from biceps and tendocalcaneus as examples for the tendon-bone attachment (enthesis), from external intercostal, brachioradialis, and external oblique muscles as examples for the linear fleshy attachment, and from infraspinatus and brachialis as examples for the fleshy attachment over a wide area.
The muscle-bone interface specimens were collected form six formalin-fixed dissecting room elderly male cadavers with no gross pathology. The whole muscle-bone interface was extracted so that each specimen included the muscle and the underlying bone tissues. The specimens were fixed in 10% neutral buffered formol saline for one week, and then decalcified with 10% EDTA for about 4-6 weeks. Dehydrated in ascending grades of alcohols, cleared in xylol, and embedded in paraffin wax. Serial sections were cut at 8-µm thickness and stained with Haematoxylin and eosin, and Masson's trichrome.
In the present work, it was found that tendon-bone attachment of either biceps brachii or tendocalcaneus was formed of four zones; zone 1 (Z1) of dense connective tissue, zone 2 (Z2) of fibrocartilage, zone 3 (Z3) of calcified fibrocartilage, and zone 4 (Z4) of compact bone. Serrated basophilic line "tidemark" was usually seen between fibrocartilage and calcified fibrocartilage zones. Moreover, differences in the distribution and population of chondrocytes occurred between zone 2 (Z2) and zone 3 (Z3).
On the other hand, the muscle-bone interface of brachialis, infraspinatus, brachioradialis, and external intercostal muscles was noticed to be formed of three zones; zone 1 (Z1) of skeletal muscle tissue, zone 2 (Z2) of dense connective tissue, and zone 3 (Z3) of compact bone. The dense connective tissue zone interposed between the skeletal muscle fibers and the bone differed in its density and structure between the studied muscles. Moreover, some regions of the attachment site of the external oblique muscle were observed to include zones of fibrocartilage and calcified fibrocartilage so that a mixture of fibrocartilaginous and fibrous attachment could be identified.
From the above mentioned findings it was concluded that three patterns of muscle-bone interfaces could be described according to the number and types of histological zones; (1) the classical pattern of tendon-bone interface (enthesis) formed of the four zones, (2) the fleshy pattern of the muscle-bone interface characterized by absence of fibrocartilage, (3) the third pattern is an admixture of the previous two patterns. The present findings would be helpful in clinical practice; especially, for the choice of the suitable muscle for transplant.
The ameliorative potential of hyphaene thebaica on streptozotocin induced dia...Prof. Hesham N. Mustafa
Background: Diabetic nephropathy (DN) is the leading cause of end-stage renal
disease. The aim of the current study is to investigate the possible beneficial effects
of Hyphaene thebaica in DN.
Materials and methods: For this, 50 male albino rats were divided into five
groups: group I — represented the control group; group II — received Hyphaene thebaica extracts of 150 mg/kg BW by oral gavage for 6 weeks; group III
— received single intraperitoneal injections of streptozotocin (50 mg/kg BW)
to induce type-2 diabetes mellitus; group IV (protective) — diabetic rats received Hyphaene thebaica extract (150 mg/kg BW) orally for 6 weeks; group V
(curative) — received Hyphaene thebaica extract (150 mg/kg BW) orally after the
diagnosis of DN.
Results: In the DN protected group, blood glucose, urea, and creatinine decreased
significantly, while insulin and C-peptide increased significantly. Moreover, cystatin C
and neutrophil gelatinase-associated lipocalin decreased. Collagen fibre deposition is increased with an apparent thickening of the parietal layer of Bowman’s
capsules and the basal lamina of convoluted tubules, as well as increase of the
immune-reaction of caspase-3 and desmin. The introduction of Hyphaene thebaica
led to greater amelioration in the biochemical markers, apoptotic alterations, and
podocyte injuries of the protected group than in the curative group.
Conclusions: Hyphaene thebaica may be advised as a good choice that can delay
diabetic renal complications. (Folia Morphol 2015; 74, 4: 447–457)
Key words: diabetic nephropathy, Hyphaene thebaica, podocyte injury,
apoptosis