This document describes the "Learn from Every Patient" (LFEP) program at Nationwide Children's Hospital, which aims to fully integrate clinical care and research. The LFEP program collects standardized clinical and research data in the electronic medical record during patient visits. This data is then extracted to a data mart where it can be analyzed to systematically improve care and advance research. While implementation of the LFEP program requires significant changes, it offers opportunities to improve patient outcomes through evidence-based care and gain a competitive advantage for organizations that can successfully integrate clinical and research activities.

1. Translating Research into the Standard of CareWilliam E. Smoyer, M.D.C. Robert Kidder Chair,Vice President and Director,Center for Clinical and Translational ResearchThe Research Institute at Nationwide Children’s HospitalProfessor of Pediatrics,The Ohio State University

2. OverviewSummarize major trends and barriers to integrating clinical care and research

3. Describe the “Learn from Every Patient” (LFEP) Program mission, model, structure, and flow

4. Share NCH experience with a LFEP Pilot Program

5. Outline resources needed to ensure LFEP success

6. Share lessons learned and opportunities !BackgroundMajor trend toward merging clinical care and medical research Information

7. Conversion to electronic medical records

8. Data use to improve and personalize health care, and reduce costs

9. Overarching Goal:

10. Improving patient outcomes through integration of clinical care and researchBackgroundMajor Barriers to Merging Clinical Care and Research Information

11. Inadequate organizational readiness

12. Infrastructure-related / financial / political

13. Inadequate information standards

14. Differing terminologies, data models, data architectures

15. Inadequate technology integration

16. Differing IT systems

17. Inadequate workflow integration

18. Differing clinical care and research processes“Learn From Every Patient” ProgramA Model for Full Integrationof Research and Clinical Care

19. “Learn from Every Patient”Program MissionTo fully integrate knowledge gained from clinical care with research to systematically advance the care of childrenIn other words…“We will learn from every patient at every visit and use that knowledge to improve the care of the children that follow”

20. Alignment of LFEP with Strategic GoalsGoal: To fully integrate knowledge gained from clinical care with research to systematically advance the care of children at NCH

21. “Learn from Every Patient”Program ModelWith IRB oversightData MartClinical + research data collection integrated into provision of careLeverage data sources, including EMR and EDW(Disease-specific data set derived from multiple data sources)Patientreceives evidence-based standardized careTranslationalResearchPeer Reviewed PublicationsSystematically improve care of all patientsDrive incremental improvements in standard of careQualityImprovement