SJS /TEN with real life case. how to treat SJS and TEN.

1. Case .
46 philpino male, k/c HTN , DLD , CKD (Bs 170) , recently diagnosed as
GOUT presented with generalized erythematous maculopapular skin rash since 3
days
Followed by appearance of blisters and involvement of mucosal membrane of oral
cavity causing him difficulty swallowing. During hospital stay developed clinical
condition worsened and was shifter to MICU.
Upon taking detailed history , he started with Allopurinol 100mg OD one month back.
NKDA before.
Driver by profession, married with 2 children, lifelong non-smoker.
Never had such skin rash before. Denied taking NSAIDs nor ABX before 3-4 weeks.
Other home medications ,
lisinopril 10mg, bisprolol 5mg, simvastatin 40mg, Lercadip 10mg.

3. UNDERSTANDING
SJS & TEN
Dr Shoaib Arshad
Allergy and immunology

52. MANAGEMENT IN ICU
• Closely followed by Dermatology, Immunology ENT, Ophthalmology, plastic surgery
, wound care teams.
• Good hydration and Topicals.
• 2 days course of IVIG (2g/kg) 120g iv od .
• NO ANTIBIOTICS
• NO STEROIDS
• After 2 weeks was discharged home and to avoid ALLOPURINOL LIFELONG.