SharpBrains @ New York Public Library
              09/25/09




        http://www.sharpbrains.com/book/
    Presentation Redistribution allowed, under Creative Commons
    Attribution-No Derivative Works License
Draw a circle with the right hand and a square
with the left one
Debunking 10 Myths

1. Genes determine the fate of our brains.
2. Aging means automatic decline.
3. Medication is the only hope for cognitive enhancement.
4. We will soon have a Magic Pill or General Solution.
5. There is only one “it” in “Use It or Lose it”.
6. All mental activity is equal.
7. After age X, no new neurons are generated in the human brain.
8. We all have something called “Brain Age”.
9. That “brain age” can be reversed by 10, 20, 30 years.
10. All human brains need the same mental exercise.
Games I am playing…




© SharpBrains
An introduction to SharpBrains


   SharpBrains (www.sharpbrains.com) is a Market
    Research & Publishing firm, co-founded in 2005 by
    Alvaro Fernandez and Dr. Elkhonon Goldberg

   SharpBrains doesn’t develop or sell products

   SharpBrains has been quoted in The New York
    Times, WSJ, CNN, Scientific American Mind, …

   Dozens of neuroscientists collaborate with
    SharpBrains
SharpBrains.com
5 Data Points




© SharpBrains
5 Data Points




© SharpBrains
5 Data Points




© SharpBrains
Chapters


   I.     The Brain and Brain Fitness 101
   II.    The 4 Pillars of Brain Maintenance
   III.   Mental Exercise vs. Mental Activity
   IV.    How to Evaluate and Choose Products
   V.     Emerging Research and Applications
   VI.    Ready For the Future?
   VII.   Opening the Debate
What is this? How many do we have?
A complex system

    Goal-oriented
                    Emotions,                Breathing,
     behavior,
                     memory                  movement
      thinking




                                Source: Rita Carter, Mapping the Mind
Parts of the cortex




                      by Morphonix
What is Brain Fitness

   The general state of feeling alert, in control,
      productive.
     Having fit brain functions, as required to function in
      society, in our occupations, in our communities. It is
      about attention, information processing, memory,
      emotional self-regulation, planning…
     It is not about “IQ”.
     It is not (mainly) about Alzheimer’s Disease.
     Can it be measured today?
Five-fingered relaxation


   Travel back to a time
       Index: when you felt a healthy exhaustion
       Middle: loving exchange
       Ring: most caring gesture you have ever received
       Little: most magnificient place you have seen




    Source: Five Good minutes, by Jeffrey Brantley
Which one doesn’t fit
Cognition and Aging

 Some areas that typically improve as we age
   Self-regulation
   Emotional functioning
   Wisdom: from problem-solving to pattern recognition
 Some areas that typically decline as we age
   Processing speed
   Attention: selective, divided
   Memory: working, recall, source
   Effortful problem-solving
What is lifelong learning?

 “Learning is physical. Learning means the
 modification, growth, and pruning of our
 neurons, connections–called synapses–
 and neuronal networks, through
 experience...When we do so, we are
 cultivating our own neuronal networks.
 We become our own gardeners”

 - Dr. James Zull, Professor of Biology and
 Biochemistry at Case Western University
What is attention and how to train it

 “…we have found no ceiling for abilities
 such as attention, including among adults.
 The more training, even with normal
 people, the higher the results.“

 - Dr. Michael Posner, Emeritus Professor at
 the University of Oregon, and first recipient
 of the Dogan Prize
Recovering from traumatic brain injury

 “There is much more optimism and hope
 today …about how many traumatic brain
 injury patients can improve, if given the
 opportunity to.”

 - Lee Woodruff, co-author of In An Instant
 with husband, reporter and TBI survivor
 Bob Woodruff
Chapters

   I.     The Brain and Brain Fitness 101

   II.    The 4 Pillars of Brain Maintenance

   III.   Mental Exercise vs. Mental Activity

   IV.    How to Evaluate and Choose Products

   V.     Emerging Research and Applications

   VI.    Ready For the Future?

   VII.   Opening the Debate
Brain Maintenance


        Neuroplasticity = The brain lifelong capacity to
          reorganize itself according to one’s experiences


        Drive good neuroplasticity through:
                 Balanced Diet
                 Physical Exercise
                 Stress Management
                 Mental Stimulation



© SharpBrains
Brain Maintenance: Mental Stimulation



      The 3 key principles for good mental stimulation are:

                 1. Novelty

                 2. Variety

                 3. Challenge




© SharpBrains
What is this?
Building a cognitive reserve to delay
Alzheimer’s symptoms

 “Individuals who lead mentally stimulating
 lives, through education, occupation and
 leisure activities, seem to have 35-40%
 less risk of manifesting Alzheimer’s
 Disease”

 - Dr. Yaakov Stern, Division Leader of the
 Cognitive Neuroscience Division of the
 Sergievsky Center at the College of
 Physicians and Surgeons of Columbia
 University, New York.
A multi-pronged approach to brain health

 “…components of a well-rounded approach
 to brain health involve:
 A) Appropriate nutrition
 B) Stimulating brain activity
 C) Physical activity
 D) Stress reduction
 E) Be Aware of side effects of medications”


 - Dr. Larry McCleary, former acting Chief of
     Pediatric Neurosurgery at Denver
     Children's Hospital
Why we need both physical and mental
 exercise

     “Ideally, combine both physical and
     mental stimulation along with social
     interactions. Why not take a good walk
     with friends to discuss a book?"

     - Dr. Arthur Kramer, Professor of
     Psychology and Director of the Biomedical
     Imaging Center at the University of Illinois




© SharpBrains
Chapters

   I.     The Brain and Brain Fitness 101
   II.    The 4 Pillars of Brain Maintenance
   III.   Mental Exercise vs. Mental Activity
   IV.    How to Evaluate and Choose Products
   V.     Emerging Research and Applications
   VI.    Ready For the Future?
   VII.   Opening the Debate
Mental Exercise vs. Mental Activity


     Which job would you choose?




                                   Source: Maguire, Woollett, & Spiers, 2006




© SharpBrains
Meditation

 “…meditation requires practice and
 dedication. It is not an easy fix… You need
 to match practice with need: understand
 the specific goals you have in mind, your
 schedule and lifestyle, and find something
 practical.”

 - Dr. Andrew Newberg, Associate Professor
 in the Department of Radiology and
 Psychiatry at the University of
 Pennsylvania
Cognitive therapy

 “Thanks to fMRI and other neuroimaging
 techniques we are starting to
 understand the impact our actions can
 have on specific parts of the brain.“

 - Dr. Judith S. Beck, Director of the Beck
 Institute for Cognitive Therapy and
 Research, and author of The Beck Diet
 Solution: Train Your Brain to Think Like a
 Thin Person
Biofeedback

     “It is important to understand the role of
     emotions: they are not “bad”. They are
     very useful signals. It is important to
     become aware of them to avoid being
     engulfed by them, and learn how to
     manage them.”

     - Dr. Brett Steenbarger, Associate
     Professor of Psychiatry and Behavioral
     Sciences, SUNY Medical University



© SharpBrains
The value and limitations of targeted training

     "What was very surprising was that there
     was also a clear benefit in auditory
     memory, which wasn’t directly trained. In
     other words, people who were 75-years-old
     performed auditory memory tasks as well
     as average 65-year-olds, so we can say
     they reversed 10 years of aging for that
     cognitive ability."

     - Dr. Liz Zelinski, Professor of Psychology
     at the University of Southern California
     Andrus Gerontology Center

© SharpBrains
Chapters

   I.     The Brain and Brain Fitness 101
   II.    The 4 Pillars of Brain Maintenance
   III.   Mental Exercise vs. Mental Activity
   IV.    How to Evaluate and Choose Products
   V.     Emerging Research and Applications
   VI.    Ready For the Future?
   VII.   Opening the Debate
Does Brain Training “Work”?


 Randomized controlled studies show improvements of
  targeted functions that last beyond training itself


 Most programs have not been on the market long enough to
  show direct long term effects vs. overall mental stimulation


 Whether a program “works” will depend on:
   What functions one wants to enhance and why
   Which program one selects and amount of practice
   Realistic expectations – there is no silver bullet
Brain-based outcomes




 Source: Klingberg et al.
One shoe doesn’t fit all

 Overall Maintenance    Targeted Training          Stress Management

  Nintendo Brain Age    Brain Fitness Classic     emWave PC
  BrainWare Safari      CogMed WMT
                                                    emWave Handheld
  FitBrains.com         DriveFit
                                                    Journey Wild Divine
  Happy-Neuron.com      Earobics
                                                    RESPeRATE
  Lumosity.com          Fast Forword
                         Insight with Cortex       Stress Eraser
  MindFit
                         Intelligym
  (m)Power
                         Vision Restoration Therapy
Evaluation checklist (www.sharpbrains.com)


   1. Are neuropsychologists behind the program?
   2. What peer-reviewed research supports it?
   3. Is there a solid Scientific Advisory Board?
   4. What are the specific benefits claimed?
   5. What cognitive function does it train?
   6. How many hours/ days per week to use it?
   7. Do the exercises teach something new?
   8. Always challenging?
   9. Does the program fit user’s specific goals?
   10. Is it more fun/ engaging than stressful?
Chapters

        I.      The Brain and Brain Fitness 101

        II.     The 4 Pillars of Brain Maintenance

        III.    Mental Exercise vs. Mental Activity

        IV.     How to Evaluate and Choose Products

        V.      Emerging Research and Applications

        VI.     Ready For the Future?

        VII.    Opening the Debate


© SharpBrains
Emerging Trends 2008-2015
Brain Fitness goes Mainstream
   1. Increasing Focus on Brain Maintenance
   2. Better Integration of Physical and Mental Exercise
   3. Public policy initiatives to drive adoption
Leveraging Better Tools
   4. Wide Use of Cognitive Assessments as Baseline
   5. More and Refined computer-based programs
   6. Low-tech options to play increasing role
A Growing Eco-System
   7. Need for Professional Development
   8. Insurance companies will introduce incentives
   9. Transfer from military research and applications
   10. Corporate Wellness adds a Brain component
A New Era

 “We have shown that working memory
 can be improved by training...I think that
 we are seeing the beginning of a new era”

 – Dr. Torkel Klingberg, Director of the
 Developmental Cognitive Neuroscience
 Lab at Karolinska Institute
Brain Fitness Culture: from Magic Pills to
Addressing Lifestyle and Bottlenecks

                                       Bottleneck



         Lifestyle                Emotional self-regulation
                                  Visual/ auditory
                                     processing
    Balanced diet                  Attention
    Aerobic exercise               Executive functions
    Stress management              Working memory
    Mental activity/ exercise      Long-term memory
    Medication management
    Sleep
The SharpBrains Guide to Brain Fitness

 "This is the only book that I know of that seamlessly
  integrates latest information about cognitive health across
  the lifespan. Very useful to anyone interested in brain
  care.” —Arthur Kramer, Ph.D., leading researcher


  1) For more information:
  http://www.sharpbrains.com/, free
  monthly eNewsletter
  2) To read book:
  Library, www.Amazon.com
  3) To contact us:
  information@sharpbrains.com

SharpBrains @ New York Public Library

  • 1.
    SharpBrains @ NewYork Public Library 09/25/09 http://www.sharpbrains.com/book/ Presentation Redistribution allowed, under Creative Commons Attribution-No Derivative Works License
  • 2.
    Draw a circlewith the right hand and a square with the left one
  • 3.
    Debunking 10 Myths 1.Genes determine the fate of our brains. 2. Aging means automatic decline. 3. Medication is the only hope for cognitive enhancement. 4. We will soon have a Magic Pill or General Solution. 5. There is only one “it” in “Use It or Lose it”. 6. All mental activity is equal. 7. After age X, no new neurons are generated in the human brain. 8. We all have something called “Brain Age”. 9. That “brain age” can be reversed by 10, 20, 30 years. 10. All human brains need the same mental exercise.
  • 4.
    Games I amplaying… © SharpBrains
  • 5.
    An introduction toSharpBrains  SharpBrains (www.sharpbrains.com) is a Market Research & Publishing firm, co-founded in 2005 by Alvaro Fernandez and Dr. Elkhonon Goldberg  SharpBrains doesn’t develop or sell products  SharpBrains has been quoted in The New York Times, WSJ, CNN, Scientific American Mind, …  Dozens of neuroscientists collaborate with SharpBrains
  • 6.
  • 7.
    5 Data Points ©SharpBrains
  • 8.
    5 Data Points ©SharpBrains
  • 9.
    5 Data Points ©SharpBrains
  • 11.
    Chapters I. The Brain and Brain Fitness 101 II. The 4 Pillars of Brain Maintenance III. Mental Exercise vs. Mental Activity IV. How to Evaluate and Choose Products V. Emerging Research and Applications VI. Ready For the Future? VII. Opening the Debate
  • 12.
    What is this?How many do we have?
  • 13.
    A complex system Goal-oriented Emotions, Breathing, behavior, memory movement thinking Source: Rita Carter, Mapping the Mind
  • 14.
    Parts of thecortex by Morphonix
  • 15.
    What is BrainFitness  The general state of feeling alert, in control, productive.  Having fit brain functions, as required to function in society, in our occupations, in our communities. It is about attention, information processing, memory, emotional self-regulation, planning…  It is not about “IQ”.  It is not (mainly) about Alzheimer’s Disease.  Can it be measured today?
  • 16.
    Five-fingered relaxation  Travel back to a time  Index: when you felt a healthy exhaustion  Middle: loving exchange  Ring: most caring gesture you have ever received  Little: most magnificient place you have seen Source: Five Good minutes, by Jeffrey Brantley
  • 17.
  • 18.
    Cognition and Aging Some areas that typically improve as we age  Self-regulation  Emotional functioning  Wisdom: from problem-solving to pattern recognition  Some areas that typically decline as we age  Processing speed  Attention: selective, divided  Memory: working, recall, source  Effortful problem-solving
  • 19.
    What is lifelonglearning? “Learning is physical. Learning means the modification, growth, and pruning of our neurons, connections–called synapses– and neuronal networks, through experience...When we do so, we are cultivating our own neuronal networks. We become our own gardeners” - Dr. James Zull, Professor of Biology and Biochemistry at Case Western University
  • 20.
    What is attentionand how to train it “…we have found no ceiling for abilities such as attention, including among adults. The more training, even with normal people, the higher the results.“ - Dr. Michael Posner, Emeritus Professor at the University of Oregon, and first recipient of the Dogan Prize
  • 21.
    Recovering from traumaticbrain injury “There is much more optimism and hope today …about how many traumatic brain injury patients can improve, if given the opportunity to.” - Lee Woodruff, co-author of In An Instant with husband, reporter and TBI survivor Bob Woodruff
  • 22.
    Chapters I. The Brain and Brain Fitness 101 II. The 4 Pillars of Brain Maintenance III. Mental Exercise vs. Mental Activity IV. How to Evaluate and Choose Products V. Emerging Research and Applications VI. Ready For the Future? VII. Opening the Debate
  • 23.
    Brain Maintenance  Neuroplasticity = The brain lifelong capacity to reorganize itself according to one’s experiences  Drive good neuroplasticity through:  Balanced Diet  Physical Exercise  Stress Management  Mental Stimulation © SharpBrains
  • 24.
    Brain Maintenance: MentalStimulation The 3 key principles for good mental stimulation are: 1. Novelty 2. Variety 3. Challenge © SharpBrains
  • 25.
  • 26.
    Building a cognitivereserve to delay Alzheimer’s symptoms “Individuals who lead mentally stimulating lives, through education, occupation and leisure activities, seem to have 35-40% less risk of manifesting Alzheimer’s Disease” - Dr. Yaakov Stern, Division Leader of the Cognitive Neuroscience Division of the Sergievsky Center at the College of Physicians and Surgeons of Columbia University, New York.
  • 27.
    A multi-pronged approachto brain health “…components of a well-rounded approach to brain health involve: A) Appropriate nutrition B) Stimulating brain activity C) Physical activity D) Stress reduction E) Be Aware of side effects of medications” - Dr. Larry McCleary, former acting Chief of Pediatric Neurosurgery at Denver Children's Hospital
  • 28.
    Why we needboth physical and mental exercise “Ideally, combine both physical and mental stimulation along with social interactions. Why not take a good walk with friends to discuss a book?" - Dr. Arthur Kramer, Professor of Psychology and Director of the Biomedical Imaging Center at the University of Illinois © SharpBrains
  • 29.
    Chapters I. The Brain and Brain Fitness 101 II. The 4 Pillars of Brain Maintenance III. Mental Exercise vs. Mental Activity IV. How to Evaluate and Choose Products V. Emerging Research and Applications VI. Ready For the Future? VII. Opening the Debate
  • 30.
    Mental Exercise vs.Mental Activity Which job would you choose? Source: Maguire, Woollett, & Spiers, 2006 © SharpBrains
  • 32.
    Meditation “…meditation requirespractice and dedication. It is not an easy fix… You need to match practice with need: understand the specific goals you have in mind, your schedule and lifestyle, and find something practical.” - Dr. Andrew Newberg, Associate Professor in the Department of Radiology and Psychiatry at the University of Pennsylvania
  • 33.
    Cognitive therapy “Thanksto fMRI and other neuroimaging techniques we are starting to understand the impact our actions can have on specific parts of the brain.“ - Dr. Judith S. Beck, Director of the Beck Institute for Cognitive Therapy and Research, and author of The Beck Diet Solution: Train Your Brain to Think Like a Thin Person
  • 34.
    Biofeedback “It is important to understand the role of emotions: they are not “bad”. They are very useful signals. It is important to become aware of them to avoid being engulfed by them, and learn how to manage them.” - Dr. Brett Steenbarger, Associate Professor of Psychiatry and Behavioral Sciences, SUNY Medical University © SharpBrains
  • 35.
    The value andlimitations of targeted training "What was very surprising was that there was also a clear benefit in auditory memory, which wasn’t directly trained. In other words, people who were 75-years-old performed auditory memory tasks as well as average 65-year-olds, so we can say they reversed 10 years of aging for that cognitive ability." - Dr. Liz Zelinski, Professor of Psychology at the University of Southern California Andrus Gerontology Center © SharpBrains
  • 36.
    Chapters I. The Brain and Brain Fitness 101 II. The 4 Pillars of Brain Maintenance III. Mental Exercise vs. Mental Activity IV. How to Evaluate and Choose Products V. Emerging Research and Applications VI. Ready For the Future? VII. Opening the Debate
  • 37.
    Does Brain Training“Work”?  Randomized controlled studies show improvements of targeted functions that last beyond training itself  Most programs have not been on the market long enough to show direct long term effects vs. overall mental stimulation  Whether a program “works” will depend on:  What functions one wants to enhance and why  Which program one selects and amount of practice  Realistic expectations – there is no silver bullet
  • 38.
  • 39.
    One shoe doesn’tfit all Overall Maintenance Targeted Training Stress Management  Nintendo Brain Age  Brain Fitness Classic  emWave PC  BrainWare Safari  CogMed WMT  emWave Handheld  FitBrains.com  DriveFit  Journey Wild Divine  Happy-Neuron.com  Earobics  RESPeRATE  Lumosity.com  Fast Forword  Insight with Cortex  Stress Eraser  MindFit  Intelligym  (m)Power  Vision Restoration Therapy
  • 40.
    Evaluation checklist (www.sharpbrains.com) 1. Are neuropsychologists behind the program? 2. What peer-reviewed research supports it? 3. Is there a solid Scientific Advisory Board? 4. What are the specific benefits claimed? 5. What cognitive function does it train? 6. How many hours/ days per week to use it? 7. Do the exercises teach something new? 8. Always challenging? 9. Does the program fit user’s specific goals? 10. Is it more fun/ engaging than stressful?
  • 41.
    Chapters I. The Brain and Brain Fitness 101 II. The 4 Pillars of Brain Maintenance III. Mental Exercise vs. Mental Activity IV. How to Evaluate and Choose Products V. Emerging Research and Applications VI. Ready For the Future? VII. Opening the Debate © SharpBrains
  • 42.
    Emerging Trends 2008-2015 BrainFitness goes Mainstream 1. Increasing Focus on Brain Maintenance 2. Better Integration of Physical and Mental Exercise 3. Public policy initiatives to drive adoption Leveraging Better Tools 4. Wide Use of Cognitive Assessments as Baseline 5. More and Refined computer-based programs 6. Low-tech options to play increasing role A Growing Eco-System 7. Need for Professional Development 8. Insurance companies will introduce incentives 9. Transfer from military research and applications 10. Corporate Wellness adds a Brain component
  • 43.
    A New Era “We have shown that working memory can be improved by training...I think that we are seeing the beginning of a new era” – Dr. Torkel Klingberg, Director of the Developmental Cognitive Neuroscience Lab at Karolinska Institute
  • 44.
    Brain Fitness Culture:from Magic Pills to Addressing Lifestyle and Bottlenecks Bottleneck Lifestyle  Emotional self-regulation  Visual/ auditory processing  Balanced diet  Attention  Aerobic exercise  Executive functions  Stress management  Working memory  Mental activity/ exercise  Long-term memory  Medication management  Sleep
  • 45.
    The SharpBrains Guideto Brain Fitness  "This is the only book that I know of that seamlessly integrates latest information about cognitive health across the lifespan. Very useful to anyone interested in brain care.” —Arthur Kramer, Ph.D., leading researcher 1) For more information: http://www.sharpbrains.com/, free monthly eNewsletter 2) To read book: Library, www.Amazon.com 3) To contact us: information@sharpbrains.com