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Schizophrenia
Treatment options
Treatment for Schizophrenia
• Medication
• Rehabilitation and Therapy
• Surgery
• Lifestyle Changes


• References
Antipsychotic, First Generation
(Typical)
• Helps patient:
  –   think more clearly
  –   reduce anxiety.
  –   Many reduce desire to hurt self
  –   Reduce desire to hurt others.

• Side effects:
  – uncontrollable movements
Antipsychotic, First Generation
(Typical)
• Chlorpromazine (Thorazine)
• Fluphenazine hydrochloride (Prolixin)
• Haloperidol (Haldol, Haldol
  Decanoate, Haloperidol LA, Peridol)
• Perphenazine (Trilafon)
• Thiothixene (Navane)
• Trifluoperazine (Stelazine)
Antipsychotic, Second
Generation (Atypical)
• Less uncontrollable shaking than the first-
  generation antipsychotics.
• More costly and
• have higher rates of metabolic side effects
  – hypertension,
  – diabetes and
  – weight gain.
Antipsychotic, Second
Generation (Atypical)
• Aripiprazole (Abilify)      • Olanzapine (Zyprexa)
• Asenapine (Saphris)         • Paliperidone (Invega)
• Clozapine (Clozaril)        • Quetiapine (Seroquel)
• Iloperidone (Fanapt)        • Ziprasidone (Geodon)
• Lurasidone (Latuda)
• Risperidone (Risperdal , Risperdal
  Consta, Risperdal M-Tab)
Therapy and Rehabilitation
• Psychotherapy
• Individual psychotherapy, Cognitive Behavioral Therapy
  (CBT)
• Group therapy
• Family therapy
• Social skills training
• Vocational rehabilitation and supported employment
• Community Treatment Programs
• ECT (Electro-Convulsive Therapy)
• Art Therapy
• Self-help groups
Surgery
• Lobotomy
 – No longer in widespread use

• New procedures
 – Antipsychotic medication delivery system implant
   – Currently being tested
Lifestyle Changes
• Nutrition
  – Healthy Diet
  – Avoid sugar, alcohol, caffeine and preservatives
  – Add omega3 and antioxidants

• Exercise
  – Including yoga
  – Improves physical and mental health

• Stress Management
  – Stress contributes to active symptoms
  – Learn to identify stressors
  – Develop relaxation techniques
References
http://emedicine.medscape.com/article/288259-medication#2
http://www.nimh.nih.gov/health/publications/schizophrenia/how-is-
schizophrenia-treated.shtml
http://psychcentral.com/disorders/schizophrenia/schizo_treatment.htm
http://www.webmd.com/schizophrenia/second-generation-antipsychotics-for-
treating-schizophrenia
http://reference.medscape.com/
http://www.depressionforums.org/forums/topic/8415-the-metabolic-side-
effects-of-atypical-antipsychot/
http://effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-
reports/?productid=453&pageaction=displayproduct
http://www.ncbi.nlm.nih.gov/pubmedhealth/
http://reference.medscape.com/drug/geodon-ziprasidone-342985#91
http://reference.medscape.com/drug/risperdal-consta-risperidone-342986#91
http://reference.medscape.com/drug/chlorpromazine-342970#91
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000603/
http://reference.medscape.com/drug/haldol-decanoate-haloperidol-
342974#91
http://reference.medscape.com/drug/perphenazine-342980#91
http://reference.medscape.com/drug/navane-thiothixene-342988#91
http://reference.medscape.com/drug/trifluoperazine-342991#91
http://reference.medscape.com/drug/abilify-discmelt-aripiprazole-342983#91
http://reference.medscape.com/drug/saphris-asenapine-999301#91
http://reference.medscape.com/drug/clozaril-fazaclo-odt-clozapine-
342972#91
http://reference.medscape.com/drug/fanapt-iloperidone-999104#91
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0005189/
http://reference.medscape.com/drug/zyprexa-relprevv-olanzapine-342979#91
http://reference.medscape.com/drug/invega-sustenna-paliperidone-
342992#91
http://reference.medscape.com/drug/seroquel-xr-quetiapine-342984#91
http://www.encyclopedia.com/topic/lobotomy.aspx
http://www.nature.com/npp/journal/v26/n6/pdf/1395869a.pdf
http://psychcentral.com/disorders/sx31t.htm
http://www.mayoclinic.com/health/schizophrenia/DS00196/DSECTION=treatme
nts-and-drugs
http://www.emedicinehealth.com/schizophrenia/page11_em.htm
http://www.emedicinehealth.com/schizophrenia/page15_em.htm
http://www.umm.edu/patiented/articles/what_psychological_therapies_schizoph
renia_000047_9.htm
Gohol, J., Schizophrenia
Treatment, http://psychcentral.com/disorders/sx31t.htm
http://www.webmd.com/a-to-z-guides/schizophrenia-social-skills-training-topic-
overview
http://www.schizophrenia.com/treatments.php
http://www.schizophrenia.com/treatments.htm#art
ECT http://www.ncbi.nlm.nih.gov/pubmed/15846598
 Group Art Therapy as an Adjunctive Treatment for People with Schizophrenia:
Multicentre Pragmatic Randomized Trial in BMJ 2012;344:e846 doi:
10.1136/bmj.e846 (Published 28 February 2012)
Keuneman, R., Weerasundera, R., & Castle, D. (2002). The role of ECT in
schizophrenia. Australasian Psychiatry, 10(4), 385.
Ruddy R, Milnes D. Art therapy for schizophrenia or schizophrenia-like
illnesses. Cochrane Database Syst Rev 2005;4:CD003728.

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Schizophrenia