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Machine Learning to Control
Prescription Drug Costs
Project Purpose
 Recognize Physicians whose drug costs are remarkably higher than predicted.
 Use machine learning algorithms with over 50 variables for hundreds of
thousands of physicians to make a prediction for each physicians annual
prescription drug costs.
 Physicians who are much higher than predicted may be strongly affected by
pharmaceutical representatives & marketing
Privatized Medicare Insurance
 Medicare is broken into three parts (A,B,
and D). Prescription drugs are provided
through Medicare Part D
 Medicare Advantage Plans are purchased
from and implemented by private
insurance companies. They provide all
parts of Medicare
 Medicare advantage plans can choose
which doctors are in their plan
Prescription Drug Costs
 Drug costs are driven up by ’brand name’
drugs.
 Annually 20 billion is spent to convince
doctors of the benefits of brand name
drugs.
 Brand name drugs do not always have
higher efficacy than generic, but are
almost always more expensive.
Dataset Description
 Dataset was comprised of two separate
csv files from Medicare.gov
 One file included information about
each physicians’ patient population
 2nd file included information on each
physician annual drug costs
 Merged data frame included over 50 features
for each physician:
 features and their percentage of total
importance to algorithm:
 Total number of prescriptions written: 39.2%
 Sum of importance of all chronic illnesses:
17.2%
 Average annual prescription cost for
respective specialty: 9.5%
 Number of Beneficiaries with Medicaid: 6.5%
 Sum of Age Demographic Information: 6.2%
Considerations for Specialties
 Specialty type strongly correlates with
prescription drug costs
 Important for algorithm to recognize
specific specialties as categorical variable
Chronic Illnesses in Relation to Medical
Specialty
 Specialist treat illness that pertain to their specific knowledge.
 In physician’s patient population only data for the illnesses that the physician
treats should correlate with total prescription drug costs.
 One reason algorithms must differentiate between specialties is to recognize and
quantify correlations between patient populations’ frequency of specific diseases
and drug costs of specific specialties
Rheumatoid Arthritis Effect on Different
Specialties Prescription Drug Costs
Percentage of patients with Rheumatoid Arthritis is correlated with Rheumatologists
prescription drug costs but not cardiologists drug costs.
Dealing with Categorical Data
 The dataset included over seventy different
specialties. Algorithms can’t effectively use
so many categorical variables.
 Dataset was filtered to include the most
common 8 specialties
 Created dummy variables so that a new
feature was created for each specialty
included.
 Additionally, a feature equal to the average
annual drug cost of respective physician’s
specialty was created
Results
 Gradient Boosting was the most effective algorithm; had a
Coefficient of Determination of .66
 Indicates 66% of the variance in drug costs was
predictable from the variables present in the data
 79.5% of physicians were no more than 40% above
predicted and 88.2% were no more than 60% above
predicted annual prescription drug costs.
 Potential causes of variance not explained by the
Coefficient of determination :
 How easily persuaded specific physician are to the marketing
and pharmaceutical companies representatives
 Doctor has a unique population or sub-specialty not
represented in data
Other Potential Applications of Project
 This data could also be useful to pharmaceutical companies.
 If a company was releasing a new medication they could look at physicians that are
outliers as potentially highly effective to market to
 Companies could put extra resources toward targeting these outliers.
 Additionally, the Algorithm and data could easily be manipulated to focus on the
specialties and types of drugs relevant to the company.

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Machine Learning to Control Medicare Prescription Drug Costs

  • 1. Machine Learning to Control Prescription Drug Costs
  • 2. Project Purpose  Recognize Physicians whose drug costs are remarkably higher than predicted.  Use machine learning algorithms with over 50 variables for hundreds of thousands of physicians to make a prediction for each physicians annual prescription drug costs.  Physicians who are much higher than predicted may be strongly affected by pharmaceutical representatives & marketing
  • 3. Privatized Medicare Insurance  Medicare is broken into three parts (A,B, and D). Prescription drugs are provided through Medicare Part D  Medicare Advantage Plans are purchased from and implemented by private insurance companies. They provide all parts of Medicare  Medicare advantage plans can choose which doctors are in their plan
  • 4. Prescription Drug Costs  Drug costs are driven up by ’brand name’ drugs.  Annually 20 billion is spent to convince doctors of the benefits of brand name drugs.  Brand name drugs do not always have higher efficacy than generic, but are almost always more expensive.
  • 5. Dataset Description  Dataset was comprised of two separate csv files from Medicare.gov  One file included information about each physicians’ patient population  2nd file included information on each physician annual drug costs  Merged data frame included over 50 features for each physician:  features and their percentage of total importance to algorithm:  Total number of prescriptions written: 39.2%  Sum of importance of all chronic illnesses: 17.2%  Average annual prescription cost for respective specialty: 9.5%  Number of Beneficiaries with Medicaid: 6.5%  Sum of Age Demographic Information: 6.2%
  • 6. Considerations for Specialties  Specialty type strongly correlates with prescription drug costs  Important for algorithm to recognize specific specialties as categorical variable
  • 7. Chronic Illnesses in Relation to Medical Specialty  Specialist treat illness that pertain to their specific knowledge.  In physician’s patient population only data for the illnesses that the physician treats should correlate with total prescription drug costs.  One reason algorithms must differentiate between specialties is to recognize and quantify correlations between patient populations’ frequency of specific diseases and drug costs of specific specialties
  • 8. Rheumatoid Arthritis Effect on Different Specialties Prescription Drug Costs Percentage of patients with Rheumatoid Arthritis is correlated with Rheumatologists prescription drug costs but not cardiologists drug costs.
  • 9. Dealing with Categorical Data  The dataset included over seventy different specialties. Algorithms can’t effectively use so many categorical variables.  Dataset was filtered to include the most common 8 specialties  Created dummy variables so that a new feature was created for each specialty included.  Additionally, a feature equal to the average annual drug cost of respective physician’s specialty was created
  • 10. Results  Gradient Boosting was the most effective algorithm; had a Coefficient of Determination of .66  Indicates 66% of the variance in drug costs was predictable from the variables present in the data  79.5% of physicians were no more than 40% above predicted and 88.2% were no more than 60% above predicted annual prescription drug costs.  Potential causes of variance not explained by the Coefficient of determination :  How easily persuaded specific physician are to the marketing and pharmaceutical companies representatives  Doctor has a unique population or sub-specialty not represented in data
  • 11.
  • 12. Other Potential Applications of Project  This data could also be useful to pharmaceutical companies.  If a company was releasing a new medication they could look at physicians that are outliers as potentially highly effective to market to  Companies could put extra resources toward targeting these outliers.  Additionally, the Algorithm and data could easily be manipulated to focus on the specialties and types of drugs relevant to the company.