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Basic Training
ISUOG Basic Training
Fetal Biometry – Dating, Assessing Size
& Estimating Fetal Weight
Basic Training
Learning objective
At the end of the lecture you will be able to:
• List the measurements commonly used in obstetric
ultrasound examinations & describe how these are used
Basic Training
Key questions
1. How, & when in gestation, should gestational age be assigned?
2. What are the key features required to measure the the crown rump
length (CRL) correctly?
3. What are the key features of the section of the fetal head required
to measure the head circumference (HC) & biparietal diameter
(BPD) correctly?
4. What are the key features of the section of the fetal abdomen
required to measure the abdominal circumference (AC) correctly?
5. What are the key features of the section of the fetal femur required
to measure the femur length (FL) correctly?
Basic Training
Topics covered
• Estimating gestational age/assessing fetal size
• Standard fetal biometry – CRL, BPD, HC, AC & FL
• Correct anatomical planes for measurement & assessment
of head, abdomen & leg
• Components for estimation of fetal weight (EFW)
• 3rd trimester gestational age (GA) assignment - late referral
Basic Training
Estimating gestational age
• Between 4w3d and 5w6d – measure mean sac diameter
(MSD) of gestational sac but do not date or assign EDD
• Between 6w and 9w6d - CRL [4 mm – 29.9 mm]
• Between 10w and 13w6d - CRL (30 mm – 84 mm)
• Between 14w and 24w - HC and FL should ‘agree’
• After 24 weeks, assess size not gestational age
Basic Training
ISUOG Practice Guidelines CRL criteria
• Midline sagittal section of whole embryo/fetus
• Oriented horizontally, with CRL measurement
line ~900 to ultrasound beam
• Fills most of the width of the screen
• Neutral position – neither flexed nor
hyperextended
• End points of crown & rump clearly defined
• Avoid inclusion of structures such as yolk sac
• Amniotic fluid visible between chin & chest
(to ensure fetus not flexed)
Ultrasound Obstet Gynecol 2013; 41: 102-113
EDD +/- 5 days (95% of cases)
59mm = 12w3d
Basic Training
INTERGROWTH-21st CRL criteria
Ioannou C et al BJOG 2013,120 (Suppl.2): 38-41
Basic Training
Correct caliper placement
50.7mm
50.7mm = 11w5d
55.8mm = 12w1d
55.8mm
Correct Incorrect
Basic Training
30 yrs, NT 2.4mm, dating by CRL (Tri 21 risks at term)
Practical implications of poor CRL technique
CRL GA Background risk Adjusted risk
52.8 11w6d 1:906 1:182
48.9 11w4d 1:906 1:143
CRL 48.9mm - incorrect
CRL 52.8mm - correct
Basic Training
Correct anatomical plane HC/BPD
http://fetalanomaly.screening.nhs.uk/standardsandpolicy
Basic Training
Correct anatomical plane HC/BPD
1. Cross section at level of lateral ventricles/
thalami (slide)
2. Midline (falx cerebri) horizontal (dip)
3. Midline equidistant from upper & lower
parietal bones (angle)
4. Cavum septum pellucidum bisects midline,
1/3 from synciput (front) to occiput (back)
5. Rugby football shape, rounded at back, more
pointed at front (rotate)
6. Skull contour regular (angle)
Basic Training
Dating by HC
• Cross section of head at level of lateral
ventricles/thalami
• HC from ellipse round outer skull border
• HC calculated from measurement of
BPD (outer to outer) + OFD (outer to
outer)
HC = (BPD + OFD) x 1.62
HC = 158.0mm = 19w
Basic Training
Dating by BPD
• Cross section of head at level of lateral
ventricles/thalami
• BPD from linear calipers across widest
diameter between parietal bones
• Upper caliper on OUTER border of upper
skull
• Lower caliper on either OUTER or INNER
border of lower skull, depending on BPD
chart used
• Skull thickness at 20 weeks~3 mm,
equivalent to ~3 days of gestation
BPD outer to outer
BPD outer to outer
BPD outer to inner
Basic Training
Dating by HC
HC = 158 mm = 19w
HC dating table HC size chart
• Look-up table to date
• Size chart for reporting
Loughna et al Ultrasound 2009, 17(3):161-167
Basic Training
Correct anatomical plane FL
1. Both ends of ossified metaphysis
clearly visible (rotate + slide)
2. Longest axis measured
3. Distal femoral epiphysis if visible or
spur artefacts should not be included
4. Angle of femur to incident beam
should correspond to technique of
reference chart (dip)
5. Recommend 00-150 to horizontal
http://fetalanomaly.screening.nhs.uk/standardsandpolicy
Basic Training
Dating by HC & FL
• Assigning GA accurately requires GA from HC
& FL to ‘agree’
• Both 50th centile – straightforward
HC = 158 mm = 19w
FL = 29 mm = 18w6d
Basic Training
Dating by HC & FL
• Assigning GA accurately requires GA from
HC & HC & FL to ‘agree’
– same centile?
– +/- 10 centiles?
– +/- 45 centiles?
• Where HC & FL ‘disagree’
– review HC & FL sections & caliper placements
– repeat sections & re-measure
– consider significance of genuine discrepancy
Basic Training
HC & FL discrepancy
Small FL (below 5th centile)
• Skeletal dysplasia
• Down’s syndrome
• ?early FGR
Refer for further assessment
Review HC & FL sections & caliper placements
Repeat sections & re-measure
Consider significance of genuine discrepancy
Small HC (below 5th centile)
• Microcephaly
• Spina bifida
Refer for further assessment
Basic Training
32 week landmarks 33 week landmarks
Landmarks & gestational age
20 week landmarks
Basic Training
Correct anatomical plane AC
Transverse section of fetal abdomen
1. As circular as possible (rotate or angle)
2. Short length of umbilical vein/at level of
portal sinus (usually rotate)
3. Stomach ‘bubble’ visualised (slide)
4. Kidneys should not be visible (slide)
http://fetalanomaly.screening.nhs.uk/standardsandpolicy
Basic Training
1. Correct short length of umbilical vein
2. Stomach ‘bubble’ visualised
3. Incorrect long length of umbilical vein
Correct Incorrect
AC sections
Basic Training
Measurement of AC
• Caliper(s) at outer surface of skin line
a. Ellipse
b. Linear
• anteroposterior diameter (APAD)
• transverse abdominal diameter (TAD)
• diameters 900 to each other, outer to outer
• AC = (APAD + TAD) x 1.57
19 week landmarks
31 week landmarks
Basic Training
Assessing fetal size
• Once the EDD has been assigned (CRL), fetal biometry
is used to assess
– Fetal growth velocity
– Fetal size
– Fetal weight
• Measurements should not be used to reassign the EDD
• Time interval between scans - at least 2 weeks
Basic Training
Fetal growth
International standards for fetal growth based on serial ultrasound measurements:
the Fetal Growth Longitudinal. Study of the INTERGROWTH-21st Project
Papageorghiou et al Lancet 2014, 384:869-79
HC BPD AC Femur
Basic Training
Fetal growth
Basic Training
Components for EFW
• AC alone
• AC, HC
• AC, HC, FL
• AC, HC, FL, BPD
Basic Training
Caliper placement & estimating fetal
weight
AC 310.3mm
FL 60.1mm
EFW (Hadlock) = 2299g
AC 322.8mm
FL 65.4mm
EFW (Hadlock) = 2837g
Basic Training
Estimated fetal weight
Hadlock 2 and 3 - most reliable formulae
- > 3 kg, % error increases
Kurmanavicius et al J Perinat Med 2004, 32:155-61
Basic Training
3rd trimester GA assignment (late referral)
• Biometry used to assess fetal size (& wt), not gestational age
• Subsequent examination(s) to assess growth velocity
Basic Training
3rd trimester GA assignment (late referral)
• Pregnancy dating >24 weeks unreliable
– ?average 30 weeks
– ?small 32 weeks
– ?large 28 weeks
• Biometry used to assess fetal size (& weight), not
gestational age
• Subsequent examination(s) to assess growth velocity
Basic Training
Key points
1. Correct the incorrect level by sliding the probe, the shape by
rotating the probe, the symmetry of the contents by angling the
probe and the position of the structures relative to the horizontal by
dipping the probe
2. Ideally pregnancies should be dated by CRL, between 10w and
13w6d, i.e. 30 mm – 84 mm
3. Pregnancies scanned for the first time between 14 and 24 weeks
should be dated by HC or FL. These two parameters should ‘agree’
4. Gestational age should not be assigned if scanning a pregnancy for
the first time after 24 weeks
Basic Training
Key points
5. Accurate dating, assessment of size &/or estimating fetal weight
requires
– The correct section(s) to be obtained
– The calipers to be placed correctly as described by the relevant
reference chart(s)
6. It is preferable not to report an inaccurate measurement than to
provide potentially clinically misleading ultrasound information
Editable text here
BASIC TRAINING
Basic Training
ISUOG Basic Training by ISUOG is licensed under a Creative Commons Attribution-NonCommercial-
NoDerivatives 4.0 International License.
Based on a work at https://www.isuog.org/education/basic-training.html.
Permissions beyond the scope of this license may be available at https://www.isuog.org/

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Lecture-10-Fetal-Biometry-Dating-Assessing-Size-Estimating-Fetal-Weight.pdf

  • 1. Basic Training ISUOG Basic Training Fetal Biometry – Dating, Assessing Size & Estimating Fetal Weight
  • 2. Basic Training Learning objective At the end of the lecture you will be able to: • List the measurements commonly used in obstetric ultrasound examinations & describe how these are used
  • 3. Basic Training Key questions 1. How, & when in gestation, should gestational age be assigned? 2. What are the key features required to measure the the crown rump length (CRL) correctly? 3. What are the key features of the section of the fetal head required to measure the head circumference (HC) & biparietal diameter (BPD) correctly? 4. What are the key features of the section of the fetal abdomen required to measure the abdominal circumference (AC) correctly? 5. What are the key features of the section of the fetal femur required to measure the femur length (FL) correctly?
  • 4. Basic Training Topics covered • Estimating gestational age/assessing fetal size • Standard fetal biometry – CRL, BPD, HC, AC & FL • Correct anatomical planes for measurement & assessment of head, abdomen & leg • Components for estimation of fetal weight (EFW) • 3rd trimester gestational age (GA) assignment - late referral
  • 5. Basic Training Estimating gestational age • Between 4w3d and 5w6d – measure mean sac diameter (MSD) of gestational sac but do not date or assign EDD • Between 6w and 9w6d - CRL [4 mm – 29.9 mm] • Between 10w and 13w6d - CRL (30 mm – 84 mm) • Between 14w and 24w - HC and FL should ‘agree’ • After 24 weeks, assess size not gestational age
  • 6. Basic Training ISUOG Practice Guidelines CRL criteria • Midline sagittal section of whole embryo/fetus • Oriented horizontally, with CRL measurement line ~900 to ultrasound beam • Fills most of the width of the screen • Neutral position – neither flexed nor hyperextended • End points of crown & rump clearly defined • Avoid inclusion of structures such as yolk sac • Amniotic fluid visible between chin & chest (to ensure fetus not flexed) Ultrasound Obstet Gynecol 2013; 41: 102-113 EDD +/- 5 days (95% of cases) 59mm = 12w3d
  • 7. Basic Training INTERGROWTH-21st CRL criteria Ioannou C et al BJOG 2013,120 (Suppl.2): 38-41
  • 8. Basic Training Correct caliper placement 50.7mm 50.7mm = 11w5d 55.8mm = 12w1d 55.8mm Correct Incorrect
  • 9. Basic Training 30 yrs, NT 2.4mm, dating by CRL (Tri 21 risks at term) Practical implications of poor CRL technique CRL GA Background risk Adjusted risk 52.8 11w6d 1:906 1:182 48.9 11w4d 1:906 1:143 CRL 48.9mm - incorrect CRL 52.8mm - correct
  • 10. Basic Training Correct anatomical plane HC/BPD http://fetalanomaly.screening.nhs.uk/standardsandpolicy
  • 11. Basic Training Correct anatomical plane HC/BPD 1. Cross section at level of lateral ventricles/ thalami (slide) 2. Midline (falx cerebri) horizontal (dip) 3. Midline equidistant from upper & lower parietal bones (angle) 4. Cavum septum pellucidum bisects midline, 1/3 from synciput (front) to occiput (back) 5. Rugby football shape, rounded at back, more pointed at front (rotate) 6. Skull contour regular (angle)
  • 12. Basic Training Dating by HC • Cross section of head at level of lateral ventricles/thalami • HC from ellipse round outer skull border • HC calculated from measurement of BPD (outer to outer) + OFD (outer to outer) HC = (BPD + OFD) x 1.62 HC = 158.0mm = 19w
  • 13. Basic Training Dating by BPD • Cross section of head at level of lateral ventricles/thalami • BPD from linear calipers across widest diameter between parietal bones • Upper caliper on OUTER border of upper skull • Lower caliper on either OUTER or INNER border of lower skull, depending on BPD chart used • Skull thickness at 20 weeks~3 mm, equivalent to ~3 days of gestation BPD outer to outer BPD outer to outer BPD outer to inner
  • 14. Basic Training Dating by HC HC = 158 mm = 19w HC dating table HC size chart • Look-up table to date • Size chart for reporting Loughna et al Ultrasound 2009, 17(3):161-167
  • 15. Basic Training Correct anatomical plane FL 1. Both ends of ossified metaphysis clearly visible (rotate + slide) 2. Longest axis measured 3. Distal femoral epiphysis if visible or spur artefacts should not be included 4. Angle of femur to incident beam should correspond to technique of reference chart (dip) 5. Recommend 00-150 to horizontal http://fetalanomaly.screening.nhs.uk/standardsandpolicy
  • 16. Basic Training Dating by HC & FL • Assigning GA accurately requires GA from HC & FL to ‘agree’ • Both 50th centile – straightforward HC = 158 mm = 19w FL = 29 mm = 18w6d
  • 17. Basic Training Dating by HC & FL • Assigning GA accurately requires GA from HC & HC & FL to ‘agree’ – same centile? – +/- 10 centiles? – +/- 45 centiles? • Where HC & FL ‘disagree’ – review HC & FL sections & caliper placements – repeat sections & re-measure – consider significance of genuine discrepancy
  • 18. Basic Training HC & FL discrepancy Small FL (below 5th centile) • Skeletal dysplasia • Down’s syndrome • ?early FGR Refer for further assessment Review HC & FL sections & caliper placements Repeat sections & re-measure Consider significance of genuine discrepancy Small HC (below 5th centile) • Microcephaly • Spina bifida Refer for further assessment
  • 19. Basic Training 32 week landmarks 33 week landmarks Landmarks & gestational age 20 week landmarks
  • 20. Basic Training Correct anatomical plane AC Transverse section of fetal abdomen 1. As circular as possible (rotate or angle) 2. Short length of umbilical vein/at level of portal sinus (usually rotate) 3. Stomach ‘bubble’ visualised (slide) 4. Kidneys should not be visible (slide) http://fetalanomaly.screening.nhs.uk/standardsandpolicy
  • 21. Basic Training 1. Correct short length of umbilical vein 2. Stomach ‘bubble’ visualised 3. Incorrect long length of umbilical vein Correct Incorrect AC sections
  • 22. Basic Training Measurement of AC • Caliper(s) at outer surface of skin line a. Ellipse b. Linear • anteroposterior diameter (APAD) • transverse abdominal diameter (TAD) • diameters 900 to each other, outer to outer • AC = (APAD + TAD) x 1.57 19 week landmarks 31 week landmarks
  • 23. Basic Training Assessing fetal size • Once the EDD has been assigned (CRL), fetal biometry is used to assess – Fetal growth velocity – Fetal size – Fetal weight • Measurements should not be used to reassign the EDD • Time interval between scans - at least 2 weeks
  • 24. Basic Training Fetal growth International standards for fetal growth based on serial ultrasound measurements: the Fetal Growth Longitudinal. Study of the INTERGROWTH-21st Project Papageorghiou et al Lancet 2014, 384:869-79 HC BPD AC Femur
  • 26. Basic Training Components for EFW • AC alone • AC, HC • AC, HC, FL • AC, HC, FL, BPD
  • 27. Basic Training Caliper placement & estimating fetal weight AC 310.3mm FL 60.1mm EFW (Hadlock) = 2299g AC 322.8mm FL 65.4mm EFW (Hadlock) = 2837g
  • 28. Basic Training Estimated fetal weight Hadlock 2 and 3 - most reliable formulae - > 3 kg, % error increases Kurmanavicius et al J Perinat Med 2004, 32:155-61
  • 29. Basic Training 3rd trimester GA assignment (late referral) • Biometry used to assess fetal size (& wt), not gestational age • Subsequent examination(s) to assess growth velocity
  • 30. Basic Training 3rd trimester GA assignment (late referral) • Pregnancy dating >24 weeks unreliable – ?average 30 weeks – ?small 32 weeks – ?large 28 weeks • Biometry used to assess fetal size (& weight), not gestational age • Subsequent examination(s) to assess growth velocity
  • 31. Basic Training Key points 1. Correct the incorrect level by sliding the probe, the shape by rotating the probe, the symmetry of the contents by angling the probe and the position of the structures relative to the horizontal by dipping the probe 2. Ideally pregnancies should be dated by CRL, between 10w and 13w6d, i.e. 30 mm – 84 mm 3. Pregnancies scanned for the first time between 14 and 24 weeks should be dated by HC or FL. These two parameters should ‘agree’ 4. Gestational age should not be assigned if scanning a pregnancy for the first time after 24 weeks
  • 32. Basic Training Key points 5. Accurate dating, assessment of size &/or estimating fetal weight requires – The correct section(s) to be obtained – The calipers to be placed correctly as described by the relevant reference chart(s) 6. It is preferable not to report an inaccurate measurement than to provide potentially clinically misleading ultrasound information
  • 33. Editable text here BASIC TRAINING Basic Training ISUOG Basic Training by ISUOG is licensed under a Creative Commons Attribution-NonCommercial- NoDerivatives 4.0 International License. Based on a work at https://www.isuog.org/education/basic-training.html. Permissions beyond the scope of this license may be available at https://www.isuog.org/