K9 Advantix is a topical flea and tick treatment for dogs that kills fleas, ticks, mosquitoes, and other parasites through its active ingredients of imidacloprid and permethrin. It is applied to the skin between the shoulder blades once a month and remains effective for 4 weeks in killing and repelling parasites. K9 Advantix comes in 4 sizes depending on the dog's weight and treats dogs as young as 7 weeks old, including pregnant and nursing females.