Chemistry Connect is AstraZeneca's platform for integrating structural and bioactivity data on a large scale. It connects compound, document, and test result data from both internal and external sources to enable more effective drug discovery. By linking chemical structures to literature and experimental data, Chemistry Connect helps scientists access SAR information and identify potentially promising compounds. It provides applications like Canvas and SARConnect to facilitate navigation of chemical and target relationships.
Athens is the capital city of Greece located near the sea. It is a place rich with culture and history, with notable sites like the Acropolis, National Archaeological Museum, and Zappeion park. Athens offers opportunities to learn about the civilization that influenced the world through its art, history and architecture. Visitors can stay at hotels like Airport Hotel Les Amis or Aristoteles and use taxis, buses, trains or walking to get around the historic yet modern city.
La Unión Europea ha anunciado nuevas sanciones contra Rusia por su invasión de Ucrania. Las sanciones incluyen prohibiciones de viaje y congelamiento de activos para más funcionarios rusos, así como restricciones a las importaciones de productos rusos de acero y tecnología. Los líderes de la UE esperan que estas medidas adicionales aumenten la presión económica sobre Rusia y la disuadan de continuar su guerra contra Ucrania.
Berol® SurfBoost AD15 - a sustainable solution for cleaningSorel Muresan
Berol SurfBoost AD15 is a readily and anaerobically biodegradable cosurfactant that boosts the degreasing performance of non-ionic surfactants. It can be used in household and industrial cleaning applications without being classified. Test results showed it provided superior grease removal compared to other cosurfactants in kitchen soil and industrial soil. Example formulations demonstrated its effectiveness in all-purpose cleaners and manual dishwashing concentrates. Berol SurfBoost AD15 enhances cleaning performance at high dilutions while reducing chemical usage.
Chemistry Connect is AstraZeneca's platform for integrating structural and bioactivity data on a large scale. It connects compound, document, and test result data from both internal and external sources to enable more effective drug discovery. By linking chemical structures to literature and experimental data, Chemistry Connect helps scientists access SAR information and identify potentially promising compounds. It provides applications like Canvas and SARConnect to facilitate navigation of chemical and target relationships.
Athens is the capital city of Greece located near the sea. It is a place rich with culture and history, with notable sites like the Acropolis, National Archaeological Museum, and Zappeion park. Athens offers opportunities to learn about the civilization that influenced the world through its art, history and architecture. Visitors can stay at hotels like Airport Hotel Les Amis or Aristoteles and use taxis, buses, trains or walking to get around the historic yet modern city.
La Unión Europea ha anunciado nuevas sanciones contra Rusia por su invasión de Ucrania. Las sanciones incluyen prohibiciones de viaje y congelamiento de activos para más funcionarios rusos, así como restricciones a las importaciones de productos rusos de acero y tecnología. Los líderes de la UE esperan que estas medidas adicionales aumenten la presión económica sobre Rusia y la disuadan de continuar su guerra contra Ucrania.
Berol® SurfBoost AD15 - a sustainable solution for cleaningSorel Muresan
Berol SurfBoost AD15 is a readily and anaerobically biodegradable cosurfactant that boosts the degreasing performance of non-ionic surfactants. It can be used in household and industrial cleaning applications without being classified. Test results showed it provided superior grease removal compared to other cosurfactants in kitchen soil and industrial soil. Example formulations demonstrated its effectiveness in all-purpose cleaners and manual dishwashing concentrates. Berol SurfBoost AD15 enhances cleaning performance at high dilutions while reducing chemical usage.
Automated spelling correction to improve recall rates of name-to-structure to...Sorel Muresan
This document discusses using automated spelling correction to improve the recall rates of name-to-structure tools for chemical text mining. It notes that the biggest cause of missing compounds when extracting chemical entities is the presence of typographical errors. The document introduces CaffeineFix, a chemical nomenclature aware automatic spell checker, that can significantly improve recall rates as a pre-processing step by correcting OCR and other errors in compound names found in patents and other texts.
Getting the Big Picture by Joining up the SAR dotsSorel Muresan
Getting the Big Picture by Joining up the SAR dots
This document discusses challenges in integrating structure and bioactivity data at large scales due to the volume and complexity of unstructured data from various sources. It describes efforts to extract chemical entities from text using natural language processing and to standardize structures. The Chemistry Connect knowledge base aims to enable searching across internal and external datasets by developing a chemical dictionary and common representation of concepts.
Challenges with CLP and solutions offered by AkzoNobelSorel Muresan
To support customers in creating new solutions to meet the stricter regulations demands AkzoNobel Surface Chemistry offers surfactants with reduced or no classification and superior cleaning performance at low concentrations.
This document summarizes a presentation on narrow range ethoxylates which provide highly targeted cleaning performance at low concentrations. Narrow range ethoxylates have a narrow distribution of ethylene oxide units which results in low residual alcohol and lower foam compared to standard ethoxylates. They are effective cleaners even at temperatures below 50°C and have applications in household, industrial and institutional cleaning products due to their performance and low viscosity at cold temperatures. Guidelines formulations provided demonstrate cleaning effectiveness for kitchen soils and in industrial and institutional applications.
Hydrotropes are organic compounds that increase the solubility of a surfactant in a formulation. Traditional hydrotropes, such as sodium cumene sulfonate, bring no additional value to the cleaning process.
Multifunctional hydrotropes are cosurfactants that bring additional value to formulations in synergy with the primary surfactant. High performance at low concentration, foam control, tolerance to alkali and electrolytes, minimal impact on the environment and low human and aquatic toxicity are examples of such additional benefits.
Akzo Nobel Surface Chemistry has a range of readily biodegradable cosurfactants for Household and Industrial & Institutional cleaning applications. The presentation will review AkzoNobel Surface Chemistry’s multifunctional hydrotropes with examples of formulations and their performance.
Patent Cheminformatics: Identification of key compounds in patentsSorel Muresan
Patents can contain valuable chemical and biological information not found in scientific journals. This document discusses extracting key compounds from patents, including identifying sources for full-text patents, extracting compounds from text, and predicting key compounds through methods like frequency of group analysis. Predicting key compounds is important as they are often the most biologically active and suitable for further development. The document provides examples of extracting known drug compounds like Bextra, Aciphex, and Aricept from early patents through these methods.
Berol® ENV226 Plus - a formulator’s delightSorel Muresan
Berol ENV226 Plus exploits the synergy between nonionic and cationic surfactants to achieve excellent wetting, fast soil penetration and effectiveness at low concentrations.
Thickening is the increase of viscosity of a liquid solution. Cleaning products are thickened to allow for easier dosage and application to the surface and to increase the contact time on inclined and vertical surfaces such as toilet bowl and tile walls. The longer adherence results in an improved removal of soil, limestone and microorganisms as well as in enhanced perfume release.
In addition to moderate to extreme thickening across pH 1 to 14, the use of surfactants provides additional benefits such as cleaning and foaming, stability in chlorine and hydrogen peroxide bleaches, fragrance solubilization, disinfection support, corrosion inhibition.
AkzoNobel Surface Chemistry has a wide range of products for thickening cleaning formulations including ethoxylated amines (Ethomeen®), quaternary amines (Arquad®), and amine oxides (Aromox®) all based on our nitrogen chemistry core technology.
The presentation will review AkzoNobel Surface Chemistry’s surfactants for thickening with examples of formulations and their performance.
Automated spelling correction to improve recall rates of name-to-structure to...Sorel Muresan
This document discusses using automated spelling correction to improve the recall rates of name-to-structure tools for chemical text mining. It notes that the biggest cause of missing compounds when extracting chemical entities is the presence of typographical errors. The document introduces CaffeineFix, a chemical nomenclature aware automatic spell checker, that can significantly improve recall rates as a pre-processing step by correcting OCR and other errors in compound names found in patents and other texts.
Getting the Big Picture by Joining up the SAR dotsSorel Muresan
Getting the Big Picture by Joining up the SAR dots
This document discusses challenges in integrating structure and bioactivity data at large scales due to the volume and complexity of unstructured data from various sources. It describes efforts to extract chemical entities from text using natural language processing and to standardize structures. The Chemistry Connect knowledge base aims to enable searching across internal and external datasets by developing a chemical dictionary and common representation of concepts.
Challenges with CLP and solutions offered by AkzoNobelSorel Muresan
To support customers in creating new solutions to meet the stricter regulations demands AkzoNobel Surface Chemistry offers surfactants with reduced or no classification and superior cleaning performance at low concentrations.
This document summarizes a presentation on narrow range ethoxylates which provide highly targeted cleaning performance at low concentrations. Narrow range ethoxylates have a narrow distribution of ethylene oxide units which results in low residual alcohol and lower foam compared to standard ethoxylates. They are effective cleaners even at temperatures below 50°C and have applications in household, industrial and institutional cleaning products due to their performance and low viscosity at cold temperatures. Guidelines formulations provided demonstrate cleaning effectiveness for kitchen soils and in industrial and institutional applications.
Hydrotropes are organic compounds that increase the solubility of a surfactant in a formulation. Traditional hydrotropes, such as sodium cumene sulfonate, bring no additional value to the cleaning process.
Multifunctional hydrotropes are cosurfactants that bring additional value to formulations in synergy with the primary surfactant. High performance at low concentration, foam control, tolerance to alkali and electrolytes, minimal impact on the environment and low human and aquatic toxicity are examples of such additional benefits.
Akzo Nobel Surface Chemistry has a range of readily biodegradable cosurfactants for Household and Industrial & Institutional cleaning applications. The presentation will review AkzoNobel Surface Chemistry’s multifunctional hydrotropes with examples of formulations and their performance.
Patent Cheminformatics: Identification of key compounds in patentsSorel Muresan
Patents can contain valuable chemical and biological information not found in scientific journals. This document discusses extracting key compounds from patents, including identifying sources for full-text patents, extracting compounds from text, and predicting key compounds through methods like frequency of group analysis. Predicting key compounds is important as they are often the most biologically active and suitable for further development. The document provides examples of extracting known drug compounds like Bextra, Aciphex, and Aricept from early patents through these methods.
Berol® ENV226 Plus - a formulator’s delightSorel Muresan
Berol ENV226 Plus exploits the synergy between nonionic and cationic surfactants to achieve excellent wetting, fast soil penetration and effectiveness at low concentrations.
Thickening is the increase of viscosity of a liquid solution. Cleaning products are thickened to allow for easier dosage and application to the surface and to increase the contact time on inclined and vertical surfaces such as toilet bowl and tile walls. The longer adherence results in an improved removal of soil, limestone and microorganisms as well as in enhanced perfume release.
In addition to moderate to extreme thickening across pH 1 to 14, the use of surfactants provides additional benefits such as cleaning and foaming, stability in chlorine and hydrogen peroxide bleaches, fragrance solubilization, disinfection support, corrosion inhibition.
AkzoNobel Surface Chemistry has a wide range of products for thickening cleaning formulations including ethoxylated amines (Ethomeen®), quaternary amines (Arquad®), and amine oxides (Aromox®) all based on our nitrogen chemistry core technology.
The presentation will review AkzoNobel Surface Chemistry’s surfactants for thickening with examples of formulations and their performance.