La temática general de la obra son vidas, muy
variadas, y la muerte. Verán, soy patólogo y todos
los días tengo que pensar en la muerte cuando
tengo un cadáver en la mesa de autopsia y
cuando tengo que dar una mala noticia por una
biopsia. El denominador común es el sufrimiento,
la enfermedad, el envejecimiento y, claro está, la
propia condición humana: la vida como la
conocemos. Esta perspectiva la he intentado
plasmar en esta obra, particularmente con
personajes considerados despreciables por todos.
Despreciables en el sentido que no son personas
con quienes te gustaría compartir un café o un
asiento y, mucho menos, tu vida. Me he tomado el
esfuerzo de describirlos para ocasionar tu
desagrado pero, al mismo tiempo, llevarte por un
relato que te haga sentir empatía por ellos. La
mayoria de los personajes mueren, excepto uno
que vive rodeado de muerte, uno que nunca
realmente estuvo vivo y dos que mueren de una
forma para renacer en otra. Pretendo, a través de
mis palabras, crear empatía por ellos. Verlos
como personas, igual que tu y yo, con virtudes y
defectos, victorias y derrotas, alegrías y tristezas,
placer y sufrimiento.
La temática general de la obra son vidas, muy
variadas, y la muerte. Verán, soy patólogo y todos
los días tengo que pensar en la muerte cuando
tengo un cadáver en la mesa de autopsia y
cuando tengo que dar una mala noticia por una
biopsia. El denominador común es el sufrimiento,
la enfermedad, el envejecimiento y, claro está, la
propia condición humana: la vida como la
conocemos. Esta perspectiva la he intentado
plasmar en esta obra, particularmente con
personajes considerados despreciables por todos.
Despreciables en el sentido que no son personas
con quienes te gustaría compartir un café o un
asiento y, mucho menos, tu vida. Me he tomado el
esfuerzo de describirlos para ocasionar tu
desagrado pero, al mismo tiempo, llevarte por un
relato que te haga sentir empatía por ellos. La
mayoria de los personajes mueren, excepto uno
que vive rodeado de muerte, uno que nunca
realmente estuvo vivo y dos que mueren de una
forma para renacer en otra. Pretendo, a través de
mis palabras, crear empatía por ellos. Verlos
como personas, igual que tu y yo, con virtudes y
defectos, victorias y derrotas, alegrías y tristezas,
placer y sufrimiento.
Control de calidad estadístico en citología de cuello uterino y vagina, en preparaciones convencionales, interpretadas según el Sistema de Bethesda 2001. Presentación para las Jornadas del Hospital Regional de David, 2017.
XXIX Jornadas Médicas del Hospital Chiriquí. Control de calidad estadístico en citología exfoliativa del cuello uterino, presentación de datos preliminares, del 2008 al 2016
Estudio descriptivo, de serie de casos, transveral. Citología de cuello uterino y vagina, del 2008 al 2016, provincia de Chiriquí, República de Panamá.
Libro de texto. Histología de Fuente Abierta. Proyecto Open Source Pathology. Capítulo UNO (versión 1.3): Microscopía y procesamiento histológico. Autor: R. Alvarado Anchisi, MD
Cancer de colon desde la perspectiva del patólogo, viernes 20 de mayo del 2016Rolando Alvarado Anchisi
Charla sobre neoplasias epiteliales de colon y recto en la República de Panamá. Valoración morfológica, factores pronósticos, incidencia y mortalidad. Policlínica Licenciado Manuel María Valdés. Tercera Jornada de Docencia del Servicio de Urgencias.
El término "nini" se refiere a un sector de la población, particularmente jóvenes, que ni estudian, ni trabajan. El término correspondiente en inglés, "neet", incluye el concepto que tampoco se encuentra en entrenamiento.
Hoy en día, constituyen un segmento social cuestionado, porque es heterogéneo y no representa una situación específica.
Cáncer de testículo en Chiriquí y Bocas del Toro, del 2009 al 2015. Hospital Regional de David, Jornadas de Docencia. Hotel Ciudad de David. Rolando Alvarado Anchisi.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Control de calidad estadístico en citología de cuello uterino y vagina, en preparaciones convencionales, interpretadas según el Sistema de Bethesda 2001. Presentación para las Jornadas del Hospital Regional de David, 2017.
XXIX Jornadas Médicas del Hospital Chiriquí. Control de calidad estadístico en citología exfoliativa del cuello uterino, presentación de datos preliminares, del 2008 al 2016
Estudio descriptivo, de serie de casos, transveral. Citología de cuello uterino y vagina, del 2008 al 2016, provincia de Chiriquí, República de Panamá.
Libro de texto. Histología de Fuente Abierta. Proyecto Open Source Pathology. Capítulo UNO (versión 1.3): Microscopía y procesamiento histológico. Autor: R. Alvarado Anchisi, MD
Cancer de colon desde la perspectiva del patólogo, viernes 20 de mayo del 2016Rolando Alvarado Anchisi
Charla sobre neoplasias epiteliales de colon y recto en la República de Panamá. Valoración morfológica, factores pronósticos, incidencia y mortalidad. Policlínica Licenciado Manuel María Valdés. Tercera Jornada de Docencia del Servicio de Urgencias.
El término "nini" se refiere a un sector de la población, particularmente jóvenes, que ni estudian, ni trabajan. El término correspondiente en inglés, "neet", incluye el concepto que tampoco se encuentra en entrenamiento.
Hoy en día, constituyen un segmento social cuestionado, porque es heterogéneo y no representa una situación específica.
Cáncer de testículo en Chiriquí y Bocas del Toro, del 2009 al 2015. Hospital Regional de David, Jornadas de Docencia. Hotel Ciudad de David. Rolando Alvarado Anchisi.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
1. 2008 2009 2010 2011 2012 2013 2014 2015
0
2,000
4,000
6,000
8,000
10,000
12,000
14,000
Cervico-vaginal cytologies, 2008 to 2015
Total cytologies
Year
Absolutefrequency
2. 2008 2009 2010 2011 2012 2013 2014 2015
0.00
20.00
40.00
60.00
80.00
100.00
120.00
140.00
160.00
180.00
ASC-US, Absolute frequency and ±1 standard deviation range
Absolute frequency +1 Standard deviation -1 Standard deviation
Year
Absolutefrequency
3. 2008 2009 2010 2011 2012 2013 2014 2015
0.00
50.00
100.00
150.00
200.00
250.00
SIL, Absolute frequency and ±1 standard deviation range
Absolute frequency +1Standard deviation -1 Standard deviation
Year
Absolutefrequency
4. 2008 2009 2010 2011 2012 2013 2014 2015
0.00
0.20
0.40
0.60
0.80
1.00
1.20
1.40
1.60
1.80
ASC-US/SIL, ratio and ±1 standard deviation range
Ratio +1 Standard deviation -1 Standard deviation
Year
ASC-US/SIL
5. 2008 2009 2010 2011 2012 2013 2014 2015
0.00%
0.50%
1.00%
1.50%
2.00%
2.50%
3.00%
3.50%
4.00%
4.50%
ASC-US, Percentage and ±1 standard deviation range
ASC-US -1 Standard deviation +1 Standard deviation
Year
Percentage
6. 2008 2009 2010 2011 2012 2013 2014 2015
0.00%
0.50%
1.00%
1.50%
2.00%
2.50%
3.00%
SIL, Percentage and ±1 standard deviation range
SIL -1 Standard deviation +1 Standard deviation
Year
Percentage