F L U I D SAND                       ELECTROLYTES
Water overview*Water comprises about    60% -70% of the total body   weight *Varies with	age	weight	gender
Factors that Determine the Amount of Water ContentAge – the older we get, water content is lesserSex/Gender – males have more water than femalesBody size/Weight– thin people have more water than chubby ones
Normal Composition in Average ManWhen a person loses more than 10% of his total body fluids,he can DIE!!!Functions of Water in the Body-Transportingnutrients to cells and     wastes from cells -Transporting hormones, enzymes, blood    platelets, and red and white blood cells-Facilitating cellular metabolism and proper     cellular chemical functioning-Facilitating digestionand promoting elimination
-Acting as asolventfor electrolytes and     non-electrolytes-Acting as a tissue lubricant and cushion
-Helping maintain normal body temperatureTwo Compartments of Fluid in the Body Intracellular fluid (ICF)(60-70%)- fluid within cells	- K is the major component Extracellular fluid (ECF)(20-30%)- fluid outside cells	- Na & Cl
Interstitial – between the cellsIntravascular – inside the blood vesselTranscellular – CSF, saliva, GIT secretions and tears
LOSS of WATERRoutes and daily body fluid excretion
SENSIBLE- An individual is aware of losing that water.
GIT / FecesWater loss through defecation/feces is 200cc
KIDNEYS / UrineWater loss through urination is 1,500ml
INSENSIBLE- An individual is unaware of losing that water.
SKIN / PerspirationWater loss through perspiration is 600ml
LUNGS / RespirationWater loss through respiration is about 300ml – 350ml
Causes of  Increased Water LossCauses of Increased Water GainFever
Diarrhea
Diaphoresis
Vomiting
Gastric suctioning
Tachypnea
Increased sodium intake
Increased sodium retention
Excessive intake of water
Excess secretion of ADHElectrolytes
ElectrolytesAnelectrolyteis a substance, that when dissolved in water, gives a solution that can conduct electricity Ion -atom or molecule carrying an electrical charge       cation –develop a positive charge                   ex. Na, K, Ca, Mg       anions –develop a negative charge                   ex. Cl, HCO, PO4These charges are the basis of chemical interactions inThe body necessary for metabolism and other function
Functions of electrolytes-promotes neuromascular irritability-maintenance of body fluid osmolarity-regulation of water balance-distribution of body fluids between compartments-Conduct an electric current that transports            energy thoughout the body
Effects of ElectrolytesThe loss of electrolytes in the body can lead to an unbalance of fluids in the body and the pH, and a damage of the electric potential between the nerve cells that transmit the nerve signals (Encarta)Major Electrolytes/Chief FunctionSodium- support muscle contraction and nerve impulse transmissionPotassium— chief regulator of cellular enzyme activity and water contentCalcium- formation of bones and teeth, nerve impulse, blood clotting, muscle contraction, B12 absorptionMagnesium— support bone mineralization, protein building, muscular contraction, nerve impulse t.Chloride — maintains osmotic pressure in blood, produces hydrochloric acidBicarbonate — body’s primary buffer systemPhosphate— involved in important chemical reactions in body, cell division and hereditary traits
Regulation of Body Fluid CompartmentsProcesses:Osmosisfluid move across a semi -	permeable membrane from an 	area of low solute concentration 	to an area of high solute  	concentration until equilibrium 	is achieved.
Diffusion The movement of particles in all directions through a solution.
 The process by which a solute (substance that is dissolved) may spread through a solution or solvent (solution in which the solute is dissolved).Active Transport
Physiologic pump that moves from an area of lower concentration to higher concentration with the use of ATP.
The sodium-potassium pump is an example of active transport.OsmolarityDescribes the concentration of solutes or dissolved particlesFiltrationis the movement of solutes and solvents by hydrostatic pressure. - the movement is from an area of greater pressure to an area of lesser pressure.Osmotic pressure   is the amount of hydrostatic pressure needed   to stop the flow of water by osmosis	  -pressure exerted by proteinsHydrostatic pressure   pressure exerted by fluid on blood vessel wall
Types of IV SolutionsISOTONIC – balance osmotic pressure Solute concentration is equal to that of the serum Fluid doesn’t shift because they’re equally concentrated and already in balanceSolution has the same osmolality as the 			extracellular fluid.		Examples:	D5W ; Normal Saline* Doesn’t cause shrinking or swelling of the cell
HYPERTONIC SOLUTIONGreater pressure than that of the blood serumFluids tend to move out of the less concentrated solution into the more concentrated Solutions have a higher concentration of solute and are more concentrated than extracellular fluids. Net movement intracellular to extracellular		Examples : 	3% saline; 5% saline* Causes the cell to shrink
HYPOTONIC SOLUTIONLesser pressure than that of the blood serumFluid shifts from the hypotonic solution into the more concentrated compartment to equalize the concentrationsSolutions have a lower concentration of solutes and is more dilute than extracellular fluid . Net movement extracellular to intracellular		Examples :	1/2 Normal Saline; 1/3 Normal Saline* Causes the cell to swell
WATER BALANCETHIRST – hypothalamusHormones	a.  ADH – posterior pituitary gland			- reabsorption of water	b.  Aldosterone – adrenal gland			- Na retention, H2O retention
ADHHypothalamus senses low blood volume  pituitary gland secretes ADH into the bloodstream 	 ADH causes the kidney to retain water 	 water retention boosts blood volume
ALDOSTERONEProduced as a result  of the renin-angiotensin mechanismActs to regulate fluid volumeAngiotensin II stimulate the adrenal gland to release aldosterone
Aldosterone causes the kidneys to retain Na and water
Increases fluid volume and sodium levelsRenin - angiotensinsystem BP decreased  renin  angiotensinogenangiotensin 1angiotensin 2
Renin – angiotensinsystemAngiotensin 2aldosterone			peripheral						vasoconstriction	increase Na reabsorptionincrease water reabsorptionIncrease plasma volume				increase blood pressure
VOLUME DISTURBANCES
FLUID VOLUME DEFICIT
Description:Dehydration in which the body’s intake is not sufficient to meet the body’s fluid needs.The goal of treatment is to restore fluid volume, replace electrolytes as needed, and eliminate the cause of the fluid volume deficit.
CAUSESDiabetes insipidusFeverDiarrheaRenal failureLack of fluid intakeMalnutritionVomitingDiaphoresis
Poor skin turgorSunken fontanelsDry mouthScanty urineNo perspirationSunken eyeballsWeight lossNo tearsWeakLethargyDizziness Extreme thirstDry skinSIGNS AND SYMPTOMS
Encourage increase oral fluid intakeAdminister IVF (LR or NSS)Monitor I & OReplace fluid loss gradually over 48 hoursMonitor Na levels, urine specific gravityMANAGEMENT
FLUID VOLUME EXCESSIncrease waterCAUSESExcess fluid or sodium intake	a.  IV administration of NSS or LR	b.  High intake of dietary NaFluid and Na retentionFluid shift into the intravascular space	a.  Burn	b.  use of plasma CHON or albumin
EdemaIncrease in weigHtPuffy eyelidsPoor skin turgorTachypneaDyspneaSigns and symptoms
MANAGEMENTMonitor I & OLimit waterSkin careTurn patient every 2 hoursO2Limit NaMonitor electrolyte values
ELECTROLYTE IMBALANCES
SODIUM (Na+)  135-145 mEq/L-principal cation in ECF-average daily requirements 2-4 grms/day-responsible for:	-serum osmolality	-water retention	-neuromuscular activity “Na pump action”	-acid- base balance-foods high in Na	-salted foods ex. ham, corned beef,  cheese etc.-regulated by the kidneys-influenced by hormone aldosterone-Chloride frequently appears in combination with Na+ion.
Hyponatremia:serum sodium level falls below 135 mEq/L. Cells become swollen.Etiology:a. loss of Nab. gains of waterc. Disease states associated with  ADH (Vasopressin)
Clinical manifestations(Hyponatremia) <135mEq/LCNS changesLethargy, headachesConfusionSeizuresComanausea/vomitingHemiparesisDiarrhea, abdominal crampsPale dry skin
Nursing Intervention1.Evaluate precipitating cause is     corrected2.monitor Na serum level3.Evaluate clinical manifestations of Na loss4.Maintain pts. safety5.Administer prescribed treatment, IV therapy
Hypernatremia:Serum sodium is more than 150 mEq/L.Cells shrink. Etiology:Water deprivationExcessive salt ingestionIncreased insensible lossWater loss diarrheaProlong fever or diaphoresis w/o water replacementNa containing parenteral solutions, corticosteroids, some antibioticsNear salt water drowningDiabetes insipidus- polyuria, polydipsia
Clinical manifestations (hypernatremia)Serum Na+>145 mEq/LThirstNausea and vomitingFlushed, dry skinFeverDry sticky membranesRough, dry, swollen tongueCNS effectsRestlessness, agitationMuscular twitching, tremor, hyper-reflexiaDisorientation, hallucinationsStupor, coma
Nursing Interventions1.Evalute precipitating cause and correct2.Monitor serum Na level3.Evaluate clinical manifestations of hypernatremia4.Administer prescribed treatment5.Report abnormal findings to MD6.Patient education for future prevention
POTASSIUM (K+): 3.5-5.0 mEq/L-Principal cation in ICF, 97%-Cannot be measured in the cells-Acute abnormal levels are life threatening1. K+<2.5 or>7.0-cardiac arrest	2. K+<3.5-hypokalemia	3. K+>5.5-hyperkalemia-Responsible for:Conduction of nerve impulses
Skeletal and cardiac muscle activity
Intracellular osmolality
Enzyme action for cellular metabolism  POTASSIUM (K+): 3.5-5.0 mEq/L-80-90% excreted in the GIT in urine-10-20% excreted in by GIT in feces-Poorly stored in the body-Daily intake is essential (40-60mEq/L)-Foods high in K+Green vegetablesDry fruitsNutsMeatCocoa, brewed coffee
Hypokalemia:<3 mEq/LEtiologyGI lossDiarrhea, GI suction, vomiting, laxativesRenal lossK loss diuretics, aldosterone, steroidsGlucocorticoids, sweat, some antibioticShift into cellsInsulin, alkalosis,TPNPoor intakeAnorexia, alcoholism, debilitation, neglect
Clinical manifestations ( hypokalemia)Fatigue, weaknessCramps, restless legsDecreased reflexesQuadra-paralysisRespiratory muscle-RenalImpaired conc. Of urineDilute frequent urinationResistance to ADH, kidney exchange Na for K-CVSensitivity to digoxinDecreased BP
Cont.Clinical manifestation (hypokalemia)-ECG changesFlat T wavesU waveArrhythmias/cardiac arrest-GIDecreased motility, paralytic ileusAnorexia, nausea, vomiting
Nursing interventionsBe aware of pt.at risk for K  excessAssess pt.taking K+P.O. for GI upsetBe aware that there are many forms of K+ supplements available. Check physicians order carefullyAssess and educate pt.concerning nutrition for adequate K+ intake
Hyperkalemia: serum value of >6 mEq/LEtiology:Pseudo hyperkalemiaExcess K+ intakeRenal excretionDrugsShift of K+ out of cells
Clinical manifestations (hyperkalemia)-ABD cramping, nausea, diarrhea-Lower extremities muscle weakness-Irritability-Paresthesias of face, tongue, feet and hands-Flaccid muscle paralysis-Bradycardia, irregular heart rate, cardiac standstill-ECG changesTall, peaked T waves, prolonged PRWidened QSR
Hyperkalemia: serum value of >6 mEq/L
Nursing InterventionsMonitor serum K+ report value >5.3Caution hyperkalemiapts.to avoid foods high in K+ like:Chocolates, coffee, tea, dried fruits and beans, meat and eggs, bananasMonitor for U/OAdminister fresh blood as orderedRegulate IV w/ K+ carefullyUtilized good phlebotomy techniques
CALCIUM :8.5-10.5 mg/dl or 4.5-5.8 mEq/LFunctions:Formation of bone and teeth
Contraction of muscle, relaxation, activation and excitation
Maintaining cardiac contraction
Cellular strength and permeability
Blood coagulation
Blocks sodium transport into the cell
Transmission of nerve impulsesCalcium ImbalancesEtiologyHypocalcemia<4.5/9 mg/dlDietChronic renal failureMal absorption syndromesAlcoholismAcute pancreatitisLoop diureticsCitrated bloodalkalosisHypercalcemia>5.5/11 mg/dl98%HyperparathyroidismThiazide diuretics malignancyImmobilityVit.A & D overdoseCa cont. antacidsRenal dysfunctionSteroidacidosis
Clinical manifestations (hypocalcemia)IrritabilityDecreased memoryDelusions, hallucinationsHyperreflexiaParasthesias+ Chvostek’s sign+ Trousseau’s signLaryngeal spasm, resp.arrestTetany, seizuresAbd’l. crampsECGProlonged QT interval
Nursing InterventionsMonitor serum Ca, VS, ECGGive PO Ca supp.30 mins.before eatingBe aware of safe administration of IV CaTeach clients to eat food high in Ca, Vit.D, proteinTake necessary precautions for confusion, seizureAssess for prolong bleeding
Clinical manifestation (Hypercalcemia)Headache, confusionDecreased memoryPsychosis, stupor, comaMuscle weaknesses, fatigueDepressed reflexesAnorexia, N/VBone pain, fracturesPolyuria, dehydrationNephrolithiasis ( kidney stones)ECGShortened QT interval
Nursing InterventionsMonitor serum Ca, VS, ECGMobilization and wt. bearing activityDiet low in CaDilute urine to prevent renal calculi formationHydrate w/ isotonic solutionsPromote excretion w/loop diureticWatch for digitalis toxicity
DEHYDRATION
Dehydration: Definitiondefined as "the excessive loss of water and electrolytes from the body“Dehydration can be caused by losing too much fluid, not drinking enough water or fluids, or both.
Dehydration: DefinitionInfants and children are more susceptible to dehydration than adults because of their smaller body weights and higher turnover of water and electrolytes. So are the elderly and those with illnesses
Causes of Dehydrationwhen losses are not replaced adequately, a deficit of  water and electrolytes develop.vomiting or diarrheaacute illness where there is loss of appetite and vomitingExcessive urine output ex. diabetes or diuretic use Excessive sweating (sports)Burns
Since diarrhea and vomiting are the most common causes of dehydration in children, the volume of fluid loss may vary from 5 ml/kg (normal) to 200 ml/kgConcentration of electrolytes lost also variesNaCl and K are the most common electrolytes lost through stools
Dehydration:Checking the main symptomsHistory taking and  do a thorough physical examination classify type of dehydration depending on the amount of water and electrolytes lostThese are reflected by the signs and symptoms the child will present
Dehydration: ClassificationDehydration is classified as no dehydration, some dehydration, or severe dehydration based on how much of the body's fluid is lost or not replenished. When severe, dehydration is a life-threatening emergencyDEATH
Clinical signs of dehydration
Poor Skin Turgor
WHO Treatment Plan AThree rules of home treatment:give extra fluidscontinue feedingadvise when to return to the doctor(if the child develops blood in the stool, drinks poorly, becomes sicker, or is not better in three days).
WHO Treatment Plan BORS(ml)  					the mother slowly gives the recommended amount of ORS by spoonfuls or sipsNote: If the child is breastfed, breast-feeding should continue.After 4 hours, reassess and reclassify dehydration, and begin feeding to provide required amounts of potassium and glucose. Wt kg x 75 for 4h
WHO Treatment Plan BIf there are no more signs of dehydration, do Plan A. If there is still some dehydration, repeatPlan B.If the child now has severe dehydration, do  Plan  C.
WHO Treatment Plan C-Give IV infusion-If IV infusion is not possible, fluids should     	be given by nasogastric tube. -If none of these are possible and the child can drink, ORS must be given by mouth. Note: In areas where cholera cannot be excluded for patients less than 2 years old with severe dehydration, antibiotics are recommended. Start Cotrimoxazole.
WHO Treatment Plan C100 ml/kg of PLRNormal saline does not correct acidosis or replace potassium losses, but can be used. Plain glucose or dextrose solutions are not acceptable for the treatment of severe dehydration.
REMEMBER:Do not give:Very sweet tea, soft drinks, and sweetened fruit drinks. (These are often hyperosmolar (high sugar content).Can cause osmotic diarrhea, worsening dehydration and hyponatremia. Also to be avoided are   fluids with purgative   action and stimulants   (e.g., coffee, some  medicinal teas or infusions).
Assessment of DehydrationGraded according to the signs and symptoms that reflect the amount of fluid lost.There are usually no signs or symptoms in the early stagesAs dehydration increases, signs and symptoms develop. Initially, thirst, restlessness, irritability, decreased skin turgor, sunken eyes and sunken fontanelles.As more losses occur, these  effects become more pronounced.
Signs of hypovolemic shock (SEQUELAE)diminished sensorium (lethargy)Lack of urine outputCool moist extremitiesA rapid and feeble pulseDecreased BPPeripheral cyanosisDEATH.
Summary of Management According to Degree of Dehydration
Summary of Management According to Degree of Dehydration
Summary of Management According to Degree of Dehydration
INTRAVENOUSFLOW RATES
IV TUBING
Calculating Administration RatesOne must know two key components before using the formula:Drop factor of the IV administration set
Amount of solution to be infused over one hourRate Calculations Macrodrip Set10 drops = 1 ml
15 drops = 1 ml
20 drops = 1 mlMicrodrip Set60 drops = 1 mlBlood Set10 drops = 1 mlCalibrated in drops per ml-this calibration is needed in calculating flow rates.
Macrodrip set is used for routine adult IV administration, depending on the manufacturer and the type of tubing.
10/15, 15/60, 20/60, commonly drop factor.
A macrodrip set is used when more exact measurements are needed, such as in pediatric units.FORMULADrip Rate (gtts or mgtts/min) =Total no. of ml       x      Drip Factor Total no. of min.
			Total number of mlqtts/min=				   × drop factor			Total number of hours 			    1000ml						      =	   	         × 20gtts/ml			     8hours              =   41-42gtts/minDoctor’s Order: Start D5LR 1L to infuse over 8 hours the drop factor is 20qtts/ml,compute for the drops/minute.
Ex. gtts/min.	Doctor’s order: Start 500ml of NS to infuse over 300 minutes. The drop factor is 10 gtts/ml. compute for the gtts/min.?Gtts/min = total no. of ml  X  drop factor                 total no. of hour               = 500ml         X      10gtts/ml                 300mins.                               = 16.66 gtts/min
Ex. gtts/min.	Doctor’s order: Start 500ml of NS to infuse over 300 minutes. The drop factor is 10 gtts/ml. compute for the gtts/min.?Gtts/min = 	total no. of ml  X  drop factor                 	total no. of hour              	 =	 500ml         X      10gtts/ml                    	 5 hours                     60                 = 	16.66 gtts/min
FORMULAml per hour =Total no. of ml				Total no of hours
total number of ml			Cc /hr=					total number of hours			                            1000ml		     		=			                           80ml/hour		                   	=              12.5hourDoctor’s Order: 1000ml of D5NM to infuse at a rate of 80cc/hour. A nurse determine that it will take, how many hours for 1L to infuse?total number of mlCc/hour    =c
Start D5LR 1L to run for 10 hours. Compute for cc/hour?	    	total number of mlcc/hour=	           total number of hour			1000cc		   =					 10hours		   =  100cc/hour
Ex. Gtts/min	D5NM 1L has been ordered by Dr. Dy for his post-mastectomy patient to be infused at rate of 20gtts/minute. In how many hours will the said IVF last?Gtts/min = _____total no. of ml_____  X drop factor                    total no. of hour              =          __1,000ml__ X 15                            20 gtts/min     60                               =                15,000                                1,200             =              12.5 hours
Other factors affecting Flow Rate:Gauge of the catheterViscosity of the infusateHeight of the IV standCondition of the veinsCondition of the patient
COMPLICATIONSCirculatory Overloadcan occur if an IV is not regulated and IV fluids infuse to rapidly for the patient’s body to handle. Signs of fluid over load:TachycardiaIncrease Blood pressureHeadacheAnxietyWheezing or signs of respiratory distressDiaphoresisRestlessnessDistended neck veinsChest pain
- If an IV is running behind schedule-colaborate with the physician to determine the patients ability to tolerate an increased flow rate particularly patients with cardiac, pulmonary and renal problem.A nurse should never arbitrarily speed up an IV to catch up if the IV is running behind the schedule.Whenever an IV rate is increased the nurse should assess the patient for increased heart rate, increase respiration or lung congestion-indication of fluid overload.
AFTERCARERegulating IV fluids is an ongoing process from the time that an IV is started until it is completed. Hourly checks of an IV should include assessing the pt’s response to the IV, the rate of an IV flow, how much fluid has infused, how much fluid remains to be infused, and the condition of the IV insertion site. Adjust the rate if the IV is not flowing at the rate that was ordered.
 	If IV fluid is flowing in slowly, the nurse should check for a kink in the tubing or a position of problem. 	If an IV is flowing to rapidly, it may be leaking out around the IV insertion site. The whole system from the insertion site to the IV bag should be examined.
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MAINTENANCE REQUIREMENTSHOLIDAY-SEGAR METHODBODY SURFACE AREA METHOD
HOLIDAY-SEGAR METHODEstimates caloric expenditure in fixed weight categoriesAssumption100 cal metabolized : 100 mL waterNot suitable for neonates < 14 daysOverestimates fluid needs
HOLIDAY-SEGAR METHOD
EXAMPLEWhat is the maintenance fluid rate for a an 8 year old child weighing 25 kg using the Holiday-Segar Method?
		100 x 10	=	1000 ml+		  50 x 10	=	  500 ml+		  20 x  5	=	  100 ml 					1600 ml/day
		4 x 10	=	40 ml+		2 x 10	=	20 ml+		1 x  5	=	  5 ml					65 ml/hr
EXERCISEUsing the Holiday-Segar Method, what is the full maintenance requirement and rate for a 10 year old patient who weighs 37 kg?
BODY SURFACE AREA METHODAssumption: caloric expenditure is related to BSANot used in children < 10 kg
BSA METHODSTANDARD VALUES FOR USE IN BODY SURFACE AREA METHOD
BSA FormulaSurface area (m2) =		ht (cm) x wt (kg)							3600
EXAMPLEUsing the BSA method, what is the maintenance requirement of an 8 year old who weighs 25 kg and is 132 cm tall?
BSA Formula		0.92 m2	=		132 cm x 25 kg							3600
Water	= 1500ml/0.92/day	= 1630 mlNa+		= 40 mEq/0.92/day	= 43.5 mEqK+		= 30 mEq/0.92/day	= 32.6 mEq
EXERCISEUsing the BSA Method, what is the maintenance requirement of a 12 year old boy who weighs 37 kg and is 142 cm tall?
DEFICIT THERAPYCalculated AssessmentClinical Assessment
CALCULATED ASSESSMENTFluid deficit (L) = preillness weight (kg) – illness weight (kg)% Dehydration = (preillness weight – illness weight)/preillness weight x 100%
CLINICAL ASSESSMENT
FLUID REPLACEMENT
ICF & ECF COMPARTMENTS
ICF & ECF COMPARTMENTSIn dehydration, there are variable losses from the extracellular and intracellular compartmentsPercentage of deficit is based on total duration of illness
BASIC MATH CONCEPTS
DECIMALSAll figures to the left of the decimal point are whole numbersAll figures to the right of the decimal point are decimal fractions. 385	=	. 3  8  5tenths.385   =    385	1000hundredthsthousandths.38   =    38              100.3   =   3          10
CHANGING FRACTIONS TO DECIMALS:Fractions can be changed to decimals by dividing the numerator and the denominator¾   =   3 ÷ 4    =  0.75
PERCENTAGEPercentage  ( % ) means hundredthsPercent ( % ) is the same as a fraction with denomination as 100.		3%  	=	31004510045%    =
CHANGING PERCENT TO A DECIMAL & CHANGING DECIMAL TO PERCENTTo change percent to a decimal, remove the percent sign and divide the number by 100 or move the decimal point two places to the left.		4% = 4/100	=   .04   or	0.04To change a decimal to a percent, multiply by 100 or move the decimal point two places to the right and place % sign.		0.04 X 100 	=    4%    or 	0.04  =   4%
RATIOA Ratio consists of two numbers as separated by a 	colon ( : )	e.g.	  1 : 4	A ratio indicates that there is a relationship between the two numbers.A ratio is an indicated fraction.		e.g. 	¼	= 	1 : 4The numbers in ratio must be expressed in the same terms.			e.g.	3 inches : 2 feet 	= 	3 : 24					(feet changes to inches)
PROPORTIONIt is a statement showing that the two ratios have equivalent values	1 : 50	=     2 : 100If one value is not known, it can be solved by using the term X.	1  : X  =  2 : 100    or         meansextremes1           2X         100~
THE METRIC SYSTEMIt is the international decimal system of weights and measures¤ 	In the metric system, fractions are expressed 	as decimals	¤	In the decimal system, the fraction ½ is 		written as 0.5METRIC SYSTEMLiter  =   vol. of fluids		milli   =   one thousandths	Gram  =  weights of solids		centi  = 	  one hundredths	Meter  = measure of length	deci  =    one tenth					mcg  =   one thousandths
RULE OF CONVERSIONWhen converting from a larger unit of measure to a smaller unit, multiply the larger unit by (1000, 100, 10) or move the decimal to the right.When converting a smaller unit of measure to a larger unit, divide the smaller unit by (1000, 100, 10) or move the decimal to the left.e.g. 	2.5 grams   =       ___________ mg.
APOTHECARIES SYSTEMGrain (gr)	Dram	    Ounce	Minims		PoundsApproximate Equivalent Value:	1 gr 		= 	60 mg	1 ml		= 	15 minims (16 minims)	1 ounce	=	30 ml	1 ounce	= 	30 Gm	1 kg 		= 	2.2 pounds	e.g.  60 gr  =    _________ mg.		        4 oz   =    _________ ml.
HOUSEHOLD MEASURES	1 teaspoon (tsp)	=    4 – 5 ml		1 Tablespoon (Tbsp) 	=    3 teaspoons (tsp)		1 Tablespoon 		=    15 ml		1 milliliter		=    15 drops (gtts)			e.g.	5  ml =  ______
CONVERSION OF TEMPERATURENormal Temperature     =      37°C       =     98°F	Conversion of Centigrade (Celsius) to Fahrenheit:	Conversion of Fahrenheit to Centigrade (Celsius):°C  =  5    ( °F )  – 32          9°F   =  9    ( °C )   +  32           5
Interpretation of Doctor’s Order for DrugsThe nurse must understand the order perfectly before acting on it > The Drug> The Dose> The Route> The FrequencyIf any of the above are unclear or open for interpretations, it is the Responsibility of the nurse to clarify the order with the physician.
Example:	The order reads : Inderal 2 x4		a. What is the Drug?		b. What is the Dose?		c. What is the Route?		d. What is the Frequency?		e. Does this order need clarification?The order reads :  Lasix 10 mg IV 1 ml O.D.		 a. What is the Drug?		b. What is the Dose?		c. What is the Route?		d. What is the Frequency?		e. Does this order need clarification?
BASIC MATH CONCEPTS
DECIMALSAll figures to the left of the decimal point are whole numbersAll figures to the right of the decimal point are decimal fractions. 385	=	. 3  8  5.385   =    385	1000tenths.38   =    38              100thousandthshundredths.3   =   3          10
CHANGING FRACTIONS TO DECIMALS:Fractions can be changed to decimals by dividing the numerator and the denominator¾   =   3 ÷ 4    =  0.75
PERCENTAGEPercentage  ( % ) means hundredthsPercent ( % ) is the same as a fraction with denomination as 100.		3%  	=	31004510045%    =
CHANGING PERCENT TO A DECIMAL & CHANGING DECIMAL TO PERCENTTo change percent to a decimal, remove the percent sign and divide the number by 100 or move the decimal point two places to the left.		4% = 4/100	=   .04   or	0.04To change a decimal to a percent, multiply by 100 or move the decimal point two places to the right and place % sign.		0.04 X 100 	=    4%    or 	0.04  =   4%
RATIOA Ratio consists of two numbers as separated by a 	colon ( : )	e.g.	  1 : 4	A ratio indicates that there is a relationship between the two numbers.A ratio is an indicated fraction.		e.g. 	¼	= 	1 : 4The numbers in ratio must be expressed in the same terms.			e.g.	3 inches : 2 feet 	= 	3 : 24					(feet changes to inches)
PROPORTIONIt is a statement showing that the two ratios have equivalent values	1 : 50	=     2 : 100If one value is not known, it can be solved by using the term X.	1  : X  =  2 : 100    or         meansextremes1           2X         100~
THE METRIC SYSTEMIt is the international decimal system of weights and measures¤ 	In the metric system, fractions are expressed 	as decimals	¤	In the decimal system, the fraction ½ is 		written as 0.5METRIC SYSTEMLiter  =   vol. of fluids		milli   =   one thousandths	Gram  =  weights of solids	centi  = 	  one hundredths	Meter  = measure of length	deci  =    one tenth					mcg  =   one thousandths
RULE OF CONVERSIONWhen converting from a larger unit of measure to a smaller unit, multiply the larger unit by (1000, 100, 10) or move the decimal to the right.When converting a smaller unit of measure to a larger unit, divide the smaller unit by (1000, 100, 10) or move the decimal to the left.e.g. 	2.5 grams   =       ___________ mg.
APOTHECARIES SYSTEMGrain (gr)	Dram	    Ounce	Minims		PoundsApproximate Equivalent Value:	1 gr 		= 	60 mg	1 ml		= 	15 minims (16 minims)	1 ounce	=	30 ml	1 ounce	= 	30 Gm	1 kg 		= 	2.2 pounds	e.g.  60 gr  =    _________ mg.		        4 oz   =    _________ ml.

Fluids And Electrolytes

  • 1.
    F L UI D SAND ELECTROLYTES
  • 2.
    Water overview*Water comprisesabout 60% -70% of the total body weight *Varies with age weight gender
  • 3.
    Factors that Determinethe Amount of Water ContentAge – the older we get, water content is lesserSex/Gender – males have more water than femalesBody size/Weight– thin people have more water than chubby ones
  • 4.
    Normal Composition inAverage ManWhen a person loses more than 10% of his total body fluids,he can DIE!!!Functions of Water in the Body-Transportingnutrients to cells and wastes from cells -Transporting hormones, enzymes, blood platelets, and red and white blood cells-Facilitating cellular metabolism and proper cellular chemical functioning-Facilitating digestionand promoting elimination
  • 5.
    -Acting as asolventforelectrolytes and non-electrolytes-Acting as a tissue lubricant and cushion
  • 6.
    -Helping maintain normalbody temperatureTwo Compartments of Fluid in the Body Intracellular fluid (ICF)(60-70%)- fluid within cells - K is the major component Extracellular fluid (ECF)(20-30%)- fluid outside cells - Na & Cl
  • 7.
    Interstitial – betweenthe cellsIntravascular – inside the blood vesselTranscellular – CSF, saliva, GIT secretions and tears
  • 8.
    LOSS of WATERRoutesand daily body fluid excretion
  • 9.
    SENSIBLE- An individualis aware of losing that water.
  • 10.
    GIT / FecesWaterloss through defecation/feces is 200cc
  • 11.
    KIDNEYS / UrineWaterloss through urination is 1,500ml
  • 12.
    INSENSIBLE- An individualis unaware of losing that water.
  • 13.
    SKIN / PerspirationWaterloss through perspiration is 600ml
  • 14.
    LUNGS / RespirationWaterloss through respiration is about 300ml – 350ml
  • 15.
    Causes of Increased Water LossCauses of Increased Water GainFever
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
    Excess secretion ofADHElectrolytes
  • 25.
    ElectrolytesAnelectrolyteis a substance,that when dissolved in water, gives a solution that can conduct electricity Ion -atom or molecule carrying an electrical charge cation –develop a positive charge ex. Na, K, Ca, Mg anions –develop a negative charge ex. Cl, HCO, PO4These charges are the basis of chemical interactions inThe body necessary for metabolism and other function
  • 26.
    Functions of electrolytes-promotesneuromascular irritability-maintenance of body fluid osmolarity-regulation of water balance-distribution of body fluids between compartments-Conduct an electric current that transports energy thoughout the body
  • 27.
    Effects of ElectrolytesTheloss of electrolytes in the body can lead to an unbalance of fluids in the body and the pH, and a damage of the electric potential between the nerve cells that transmit the nerve signals (Encarta)Major Electrolytes/Chief FunctionSodium- support muscle contraction and nerve impulse transmissionPotassium— chief regulator of cellular enzyme activity and water contentCalcium- formation of bones and teeth, nerve impulse, blood clotting, muscle contraction, B12 absorptionMagnesium— support bone mineralization, protein building, muscular contraction, nerve impulse t.Chloride — maintains osmotic pressure in blood, produces hydrochloric acidBicarbonate — body’s primary buffer systemPhosphate— involved in important chemical reactions in body, cell division and hereditary traits
  • 28.
    Regulation of BodyFluid CompartmentsProcesses:Osmosisfluid move across a semi - permeable membrane from an area of low solute concentration to an area of high solute concentration until equilibrium is achieved.
  • 29.
    Diffusion The movementof particles in all directions through a solution.
  • 30.
    The processby which a solute (substance that is dissolved) may spread through a solution or solvent (solution in which the solute is dissolved).Active Transport
  • 31.
    Physiologic pump thatmoves from an area of lower concentration to higher concentration with the use of ATP.
  • 32.
    The sodium-potassium pumpis an example of active transport.OsmolarityDescribes the concentration of solutes or dissolved particlesFiltrationis the movement of solutes and solvents by hydrostatic pressure. - the movement is from an area of greater pressure to an area of lesser pressure.Osmotic pressure is the amount of hydrostatic pressure needed to stop the flow of water by osmosis -pressure exerted by proteinsHydrostatic pressure pressure exerted by fluid on blood vessel wall
  • 33.
    Types of IVSolutionsISOTONIC – balance osmotic pressure Solute concentration is equal to that of the serum Fluid doesn’t shift because they’re equally concentrated and already in balanceSolution has the same osmolality as the extracellular fluid. Examples: D5W ; Normal Saline* Doesn’t cause shrinking or swelling of the cell
  • 34.
    HYPERTONIC SOLUTIONGreater pressurethan that of the blood serumFluids tend to move out of the less concentrated solution into the more concentrated Solutions have a higher concentration of solute and are more concentrated than extracellular fluids. Net movement intracellular to extracellular Examples : 3% saline; 5% saline* Causes the cell to shrink
  • 35.
    HYPOTONIC SOLUTIONLesser pressurethan that of the blood serumFluid shifts from the hypotonic solution into the more concentrated compartment to equalize the concentrationsSolutions have a lower concentration of solutes and is more dilute than extracellular fluid . Net movement extracellular to intracellular Examples : 1/2 Normal Saline; 1/3 Normal Saline* Causes the cell to swell
  • 36.
    WATER BALANCETHIRST –hypothalamusHormones a. ADH – posterior pituitary gland - reabsorption of water b. Aldosterone – adrenal gland - Na retention, H2O retention
  • 37.
    ADHHypothalamus senses lowblood volume  pituitary gland secretes ADH into the bloodstream  ADH causes the kidney to retain water  water retention boosts blood volume
  • 38.
    ALDOSTERONEProduced as aresult of the renin-angiotensin mechanismActs to regulate fluid volumeAngiotensin II stimulate the adrenal gland to release aldosterone
  • 39.
    Aldosterone causes thekidneys to retain Na and water
  • 40.
    Increases fluid volumeand sodium levelsRenin - angiotensinsystem BP decreased  renin  angiotensinogenangiotensin 1angiotensin 2
  • 41.
    Renin – angiotensinsystemAngiotensin2aldosterone peripheral vasoconstriction increase Na reabsorptionincrease water reabsorptionIncrease plasma volume increase blood pressure
  • 42.
  • 43.
  • 44.
    Description:Dehydration in whichthe body’s intake is not sufficient to meet the body’s fluid needs.The goal of treatment is to restore fluid volume, replace electrolytes as needed, and eliminate the cause of the fluid volume deficit.
  • 45.
    CAUSESDiabetes insipidusFeverDiarrheaRenal failureLackof fluid intakeMalnutritionVomitingDiaphoresis
  • 46.
    Poor skin turgorSunkenfontanelsDry mouthScanty urineNo perspirationSunken eyeballsWeight lossNo tearsWeakLethargyDizziness Extreme thirstDry skinSIGNS AND SYMPTOMS
  • 47.
    Encourage increase oralfluid intakeAdminister IVF (LR or NSS)Monitor I & OReplace fluid loss gradually over 48 hoursMonitor Na levels, urine specific gravityMANAGEMENT
  • 48.
    FLUID VOLUME EXCESSIncreasewaterCAUSESExcess fluid or sodium intake a. IV administration of NSS or LR b. High intake of dietary NaFluid and Na retentionFluid shift into the intravascular space a. Burn b. use of plasma CHON or albumin
  • 49.
    EdemaIncrease in weigHtPuffyeyelidsPoor skin turgorTachypneaDyspneaSigns and symptoms
  • 50.
    MANAGEMENTMonitor I &OLimit waterSkin careTurn patient every 2 hoursO2Limit NaMonitor electrolyte values
  • 51.
  • 52.
    SODIUM (Na+) 135-145 mEq/L-principal cation in ECF-average daily requirements 2-4 grms/day-responsible for: -serum osmolality -water retention -neuromuscular activity “Na pump action” -acid- base balance-foods high in Na -salted foods ex. ham, corned beef, cheese etc.-regulated by the kidneys-influenced by hormone aldosterone-Chloride frequently appears in combination with Na+ion.
  • 53.
    Hyponatremia:serum sodium levelfalls below 135 mEq/L. Cells become swollen.Etiology:a. loss of Nab. gains of waterc. Disease states associated with ADH (Vasopressin)
  • 54.
    Clinical manifestations(Hyponatremia) <135mEq/LCNSchangesLethargy, headachesConfusionSeizuresComanausea/vomitingHemiparesisDiarrhea, abdominal crampsPale dry skin
  • 55.
    Nursing Intervention1.Evaluate precipitatingcause is corrected2.monitor Na serum level3.Evaluate clinical manifestations of Na loss4.Maintain pts. safety5.Administer prescribed treatment, IV therapy
  • 56.
    Hypernatremia:Serum sodium ismore than 150 mEq/L.Cells shrink. Etiology:Water deprivationExcessive salt ingestionIncreased insensible lossWater loss diarrheaProlong fever or diaphoresis w/o water replacementNa containing parenteral solutions, corticosteroids, some antibioticsNear salt water drowningDiabetes insipidus- polyuria, polydipsia
  • 57.
    Clinical manifestations (hypernatremia)SerumNa+>145 mEq/LThirstNausea and vomitingFlushed, dry skinFeverDry sticky membranesRough, dry, swollen tongueCNS effectsRestlessness, agitationMuscular twitching, tremor, hyper-reflexiaDisorientation, hallucinationsStupor, coma
  • 58.
    Nursing Interventions1.Evalute precipitatingcause and correct2.Monitor serum Na level3.Evaluate clinical manifestations of hypernatremia4.Administer prescribed treatment5.Report abnormal findings to MD6.Patient education for future prevention
  • 60.
    POTASSIUM (K+): 3.5-5.0mEq/L-Principal cation in ICF, 97%-Cannot be measured in the cells-Acute abnormal levels are life threatening1. K+<2.5 or>7.0-cardiac arrest 2. K+<3.5-hypokalemia 3. K+>5.5-hyperkalemia-Responsible for:Conduction of nerve impulses
  • 61.
    Skeletal and cardiacmuscle activity
  • 62.
  • 63.
    Enzyme action forcellular metabolism POTASSIUM (K+): 3.5-5.0 mEq/L-80-90% excreted in the GIT in urine-10-20% excreted in by GIT in feces-Poorly stored in the body-Daily intake is essential (40-60mEq/L)-Foods high in K+Green vegetablesDry fruitsNutsMeatCocoa, brewed coffee
  • 64.
    Hypokalemia:<3 mEq/LEtiologyGI lossDiarrhea,GI suction, vomiting, laxativesRenal lossK loss diuretics, aldosterone, steroidsGlucocorticoids, sweat, some antibioticShift into cellsInsulin, alkalosis,TPNPoor intakeAnorexia, alcoholism, debilitation, neglect
  • 65.
    Clinical manifestations (hypokalemia)Fatigue, weaknessCramps, restless legsDecreased reflexesQuadra-paralysisRespiratory muscle-RenalImpaired conc. Of urineDilute frequent urinationResistance to ADH, kidney exchange Na for K-CVSensitivity to digoxinDecreased BP
  • 66.
    Cont.Clinical manifestation (hypokalemia)-ECGchangesFlat T wavesU waveArrhythmias/cardiac arrest-GIDecreased motility, paralytic ileusAnorexia, nausea, vomiting
  • 67.
    Nursing interventionsBe awareof pt.at risk for K excessAssess pt.taking K+P.O. for GI upsetBe aware that there are many forms of K+ supplements available. Check physicians order carefullyAssess and educate pt.concerning nutrition for adequate K+ intake
  • 68.
    Hyperkalemia: serum valueof >6 mEq/LEtiology:Pseudo hyperkalemiaExcess K+ intakeRenal excretionDrugsShift of K+ out of cells
  • 69.
    Clinical manifestations (hyperkalemia)-ABDcramping, nausea, diarrhea-Lower extremities muscle weakness-Irritability-Paresthesias of face, tongue, feet and hands-Flaccid muscle paralysis-Bradycardia, irregular heart rate, cardiac standstill-ECG changesTall, peaked T waves, prolonged PRWidened QSR
  • 70.
  • 71.
    Nursing InterventionsMonitor serumK+ report value >5.3Caution hyperkalemiapts.to avoid foods high in K+ like:Chocolates, coffee, tea, dried fruits and beans, meat and eggs, bananasMonitor for U/OAdminister fresh blood as orderedRegulate IV w/ K+ carefullyUtilized good phlebotomy techniques
  • 72.
    CALCIUM :8.5-10.5 mg/dlor 4.5-5.8 mEq/LFunctions:Formation of bone and teeth
  • 73.
    Contraction of muscle,relaxation, activation and excitation
  • 74.
  • 75.
  • 76.
  • 77.
  • 78.
    Transmission of nerveimpulsesCalcium ImbalancesEtiologyHypocalcemia<4.5/9 mg/dlDietChronic renal failureMal absorption syndromesAlcoholismAcute pancreatitisLoop diureticsCitrated bloodalkalosisHypercalcemia>5.5/11 mg/dl98%HyperparathyroidismThiazide diuretics malignancyImmobilityVit.A & D overdoseCa cont. antacidsRenal dysfunctionSteroidacidosis
  • 79.
    Clinical manifestations (hypocalcemia)IrritabilityDecreasedmemoryDelusions, hallucinationsHyperreflexiaParasthesias+ Chvostek’s sign+ Trousseau’s signLaryngeal spasm, resp.arrestTetany, seizuresAbd’l. crampsECGProlonged QT interval
  • 80.
    Nursing InterventionsMonitor serumCa, VS, ECGGive PO Ca supp.30 mins.before eatingBe aware of safe administration of IV CaTeach clients to eat food high in Ca, Vit.D, proteinTake necessary precautions for confusion, seizureAssess for prolong bleeding
  • 81.
    Clinical manifestation (Hypercalcemia)Headache,confusionDecreased memoryPsychosis, stupor, comaMuscle weaknesses, fatigueDepressed reflexesAnorexia, N/VBone pain, fracturesPolyuria, dehydrationNephrolithiasis ( kidney stones)ECGShortened QT interval
  • 82.
    Nursing InterventionsMonitor serumCa, VS, ECGMobilization and wt. bearing activityDiet low in CaDilute urine to prevent renal calculi formationHydrate w/ isotonic solutionsPromote excretion w/loop diureticWatch for digitalis toxicity
  • 83.
  • 84.
    Dehydration: Definitiondefined as"the excessive loss of water and electrolytes from the body“Dehydration can be caused by losing too much fluid, not drinking enough water or fluids, or both.
  • 85.
    Dehydration: DefinitionInfants andchildren are more susceptible to dehydration than adults because of their smaller body weights and higher turnover of water and electrolytes. So are the elderly and those with illnesses
  • 86.
    Causes of Dehydrationwhenlosses are not replaced adequately, a deficit of water and electrolytes develop.vomiting or diarrheaacute illness where there is loss of appetite and vomitingExcessive urine output ex. diabetes or diuretic use Excessive sweating (sports)Burns
  • 87.
    Since diarrhea andvomiting are the most common causes of dehydration in children, the volume of fluid loss may vary from 5 ml/kg (normal) to 200 ml/kgConcentration of electrolytes lost also variesNaCl and K are the most common electrolytes lost through stools
  • 88.
    Dehydration:Checking the mainsymptomsHistory taking and do a thorough physical examination classify type of dehydration depending on the amount of water and electrolytes lostThese are reflected by the signs and symptoms the child will present
  • 89.
    Dehydration: ClassificationDehydration isclassified as no dehydration, some dehydration, or severe dehydration based on how much of the body's fluid is lost or not replenished. When severe, dehydration is a life-threatening emergencyDEATH
  • 90.
  • 92.
  • 93.
    WHO Treatment PlanAThree rules of home treatment:give extra fluidscontinue feedingadvise when to return to the doctor(if the child develops blood in the stool, drinks poorly, becomes sicker, or is not better in three days).
  • 94.
    WHO Treatment PlanBORS(ml) the mother slowly gives the recommended amount of ORS by spoonfuls or sipsNote: If the child is breastfed, breast-feeding should continue.After 4 hours, reassess and reclassify dehydration, and begin feeding to provide required amounts of potassium and glucose. Wt kg x 75 for 4h
  • 95.
    WHO Treatment PlanBIf there are no more signs of dehydration, do Plan A. If there is still some dehydration, repeatPlan B.If the child now has severe dehydration, do Plan  C.
  • 96.
    WHO Treatment PlanC-Give IV infusion-If IV infusion is not possible, fluids should be given by nasogastric tube. -If none of these are possible and the child can drink, ORS must be given by mouth. Note: In areas where cholera cannot be excluded for patients less than 2 years old with severe dehydration, antibiotics are recommended. Start Cotrimoxazole.
  • 97.
    WHO Treatment PlanC100 ml/kg of PLRNormal saline does not correct acidosis or replace potassium losses, but can be used. Plain glucose or dextrose solutions are not acceptable for the treatment of severe dehydration.
  • 98.
    REMEMBER:Do not give:Verysweet tea, soft drinks, and sweetened fruit drinks. (These are often hyperosmolar (high sugar content).Can cause osmotic diarrhea, worsening dehydration and hyponatremia. Also to be avoided are fluids with purgative action and stimulants (e.g., coffee, some medicinal teas or infusions).
  • 99.
    Assessment of DehydrationGradedaccording to the signs and symptoms that reflect the amount of fluid lost.There are usually no signs or symptoms in the early stagesAs dehydration increases, signs and symptoms develop. Initially, thirst, restlessness, irritability, decreased skin turgor, sunken eyes and sunken fontanelles.As more losses occur, these effects become more pronounced.
  • 100.
    Signs of hypovolemicshock (SEQUELAE)diminished sensorium (lethargy)Lack of urine outputCool moist extremitiesA rapid and feeble pulseDecreased BPPeripheral cyanosisDEATH.
  • 101.
    Summary of ManagementAccording to Degree of Dehydration
  • 102.
    Summary of ManagementAccording to Degree of Dehydration
  • 103.
    Summary of ManagementAccording to Degree of Dehydration
  • 104.
  • 105.
  • 106.
    Calculating Administration RatesOnemust know two key components before using the formula:Drop factor of the IV administration set
  • 107.
    Amount of solutionto be infused over one hourRate Calculations Macrodrip Set10 drops = 1 ml
  • 108.
  • 109.
    20 drops =1 mlMicrodrip Set60 drops = 1 mlBlood Set10 drops = 1 mlCalibrated in drops per ml-this calibration is needed in calculating flow rates.
  • 110.
    Macrodrip set isused for routine adult IV administration, depending on the manufacturer and the type of tubing.
  • 111.
    10/15, 15/60, 20/60,commonly drop factor.
  • 112.
    A macrodrip setis used when more exact measurements are needed, such as in pediatric units.FORMULADrip Rate (gtts or mgtts/min) =Total no. of ml x Drip Factor Total no. of min.
  • 113.
    Total number ofmlqtts/min= × drop factor Total number of hours 1000ml = × 20gtts/ml 8hours = 41-42gtts/minDoctor’s Order: Start D5LR 1L to infuse over 8 hours the drop factor is 20qtts/ml,compute for the drops/minute.
  • 114.
    Ex. gtts/min. Doctor’s order:Start 500ml of NS to infuse over 300 minutes. The drop factor is 10 gtts/ml. compute for the gtts/min.?Gtts/min = total no. of ml X drop factor total no. of hour = 500ml X 10gtts/ml 300mins. = 16.66 gtts/min
  • 115.
    Ex. gtts/min. Doctor’s order:Start 500ml of NS to infuse over 300 minutes. The drop factor is 10 gtts/ml. compute for the gtts/min.?Gtts/min = total no. of ml X drop factor total no. of hour = 500ml X 10gtts/ml 5 hours 60 = 16.66 gtts/min
  • 116.
    FORMULAml per hour=Total no. of ml Total no of hours
  • 117.
    total number ofml Cc /hr= total number of hours 1000ml = 80ml/hour = 12.5hourDoctor’s Order: 1000ml of D5NM to infuse at a rate of 80cc/hour. A nurse determine that it will take, how many hours for 1L to infuse?total number of mlCc/hour =c
  • 118.
    Start D5LR 1Lto run for 10 hours. Compute for cc/hour? total number of mlcc/hour= total number of hour 1000cc = 10hours = 100cc/hour
  • 119.
    Ex. Gtts/min D5NM 1Lhas been ordered by Dr. Dy for his post-mastectomy patient to be infused at rate of 20gtts/minute. In how many hours will the said IVF last?Gtts/min = _____total no. of ml_____ X drop factor total no. of hour = __1,000ml__ X 15 20 gtts/min 60 = 15,000 1,200 = 12.5 hours
  • 120.
    Other factors affectingFlow Rate:Gauge of the catheterViscosity of the infusateHeight of the IV standCondition of the veinsCondition of the patient
  • 121.
    COMPLICATIONSCirculatory Overloadcan occurif an IV is not regulated and IV fluids infuse to rapidly for the patient’s body to handle. Signs of fluid over load:TachycardiaIncrease Blood pressureHeadacheAnxietyWheezing or signs of respiratory distressDiaphoresisRestlessnessDistended neck veinsChest pain
  • 122.
    - If anIV is running behind schedule-colaborate with the physician to determine the patients ability to tolerate an increased flow rate particularly patients with cardiac, pulmonary and renal problem.A nurse should never arbitrarily speed up an IV to catch up if the IV is running behind the schedule.Whenever an IV rate is increased the nurse should assess the patient for increased heart rate, increase respiration or lung congestion-indication of fluid overload.
  • 123.
    AFTERCARERegulating IV fluidsis an ongoing process from the time that an IV is started until it is completed. Hourly checks of an IV should include assessing the pt’s response to the IV, the rate of an IV flow, how much fluid has infused, how much fluid remains to be infused, and the condition of the IV insertion site. Adjust the rate if the IV is not flowing at the rate that was ordered.
  • 124.
    If IVfluid is flowing in slowly, the nurse should check for a kink in the tubing or a position of problem. If an IV is flowing to rapidly, it may be leaking out around the IV insertion site. The whole system from the insertion site to the IV bag should be examined.
  • 125.
    Thank you verymuch for listening
  • 126.
  • 127.
    HOLIDAY-SEGAR METHODEstimates caloricexpenditure in fixed weight categoriesAssumption100 cal metabolized : 100 mL waterNot suitable for neonates < 14 daysOverestimates fluid needs
  • 128.
  • 129.
    EXAMPLEWhat is themaintenance fluid rate for a an 8 year old child weighing 25 kg using the Holiday-Segar Method?
  • 130.
    100 x 10 = 1000ml+ 50 x 10 = 500 ml+ 20 x 5 = 100 ml 1600 ml/day
  • 131.
    4 x 10 = 40ml+ 2 x 10 = 20 ml+ 1 x 5 = 5 ml 65 ml/hr
  • 132.
    EXERCISEUsing the Holiday-SegarMethod, what is the full maintenance requirement and rate for a 10 year old patient who weighs 37 kg?
  • 133.
    BODY SURFACE AREAMETHODAssumption: caloric expenditure is related to BSANot used in children < 10 kg
  • 134.
    BSA METHODSTANDARD VALUESFOR USE IN BODY SURFACE AREA METHOD
  • 136.
    BSA FormulaSurface area(m2) = ht (cm) x wt (kg) 3600
  • 137.
    EXAMPLEUsing the BSAmethod, what is the maintenance requirement of an 8 year old who weighs 25 kg and is 132 cm tall?
  • 138.
  • 139.
    Water = 1500ml/0.92/day = 1630mlNa+ = 40 mEq/0.92/day = 43.5 mEqK+ = 30 mEq/0.92/day = 32.6 mEq
  • 140.
    EXERCISEUsing the BSAMethod, what is the maintenance requirement of a 12 year old boy who weighs 37 kg and is 142 cm tall?
  • 141.
  • 142.
    CALCULATED ASSESSMENTFluid deficit(L) = preillness weight (kg) – illness weight (kg)% Dehydration = (preillness weight – illness weight)/preillness weight x 100%
  • 143.
  • 144.
  • 145.
    ICF & ECFCOMPARTMENTS
  • 146.
    ICF & ECFCOMPARTMENTSIn dehydration, there are variable losses from the extracellular and intracellular compartmentsPercentage of deficit is based on total duration of illness
  • 148.
  • 149.
    DECIMALSAll figures tothe left of the decimal point are whole numbersAll figures to the right of the decimal point are decimal fractions. 385 = . 3 8 5tenths.385 = 385 1000hundredthsthousandths.38 = 38 100.3 = 3 10
  • 150.
    CHANGING FRACTIONS TODECIMALS:Fractions can be changed to decimals by dividing the numerator and the denominator¾ = 3 ÷ 4 = 0.75
  • 151.
    PERCENTAGEPercentage (% ) means hundredthsPercent ( % ) is the same as a fraction with denomination as 100. 3% = 31004510045% =
  • 152.
    CHANGING PERCENT TOA DECIMAL & CHANGING DECIMAL TO PERCENTTo change percent to a decimal, remove the percent sign and divide the number by 100 or move the decimal point two places to the left. 4% = 4/100 = .04 or 0.04To change a decimal to a percent, multiply by 100 or move the decimal point two places to the right and place % sign. 0.04 X 100 = 4% or 0.04 = 4%
  • 153.
    RATIOA Ratio consistsof two numbers as separated by a colon ( : ) e.g. 1 : 4 A ratio indicates that there is a relationship between the two numbers.A ratio is an indicated fraction. e.g. ¼ = 1 : 4The numbers in ratio must be expressed in the same terms. e.g. 3 inches : 2 feet = 3 : 24 (feet changes to inches)
  • 154.
    PROPORTIONIt is astatement showing that the two ratios have equivalent values 1 : 50 = 2 : 100If one value is not known, it can be solved by using the term X. 1 : X = 2 : 100 or meansextremes1 2X 100~
  • 155.
    THE METRIC SYSTEMItis the international decimal system of weights and measures¤ In the metric system, fractions are expressed as decimals ¤ In the decimal system, the fraction ½ is written as 0.5METRIC SYSTEMLiter = vol. of fluids milli = one thousandths Gram = weights of solids centi = one hundredths Meter = measure of length deci = one tenth mcg = one thousandths
  • 156.
    RULE OF CONVERSIONWhenconverting from a larger unit of measure to a smaller unit, multiply the larger unit by (1000, 100, 10) or move the decimal to the right.When converting a smaller unit of measure to a larger unit, divide the smaller unit by (1000, 100, 10) or move the decimal to the left.e.g. 2.5 grams = ___________ mg.
  • 157.
    APOTHECARIES SYSTEMGrain (gr) Dram Ounce Minims PoundsApproximate Equivalent Value: 1 gr = 60 mg 1 ml = 15 minims (16 minims) 1 ounce = 30 ml 1 ounce = 30 Gm 1 kg = 2.2 pounds e.g. 60 gr = _________ mg. 4 oz = _________ ml.
  • 158.
    HOUSEHOLD MEASURES 1 teaspoon(tsp) = 4 – 5 ml 1 Tablespoon (Tbsp) = 3 teaspoons (tsp) 1 Tablespoon = 15 ml 1 milliliter = 15 drops (gtts) e.g. 5 ml = ______
  • 159.
    CONVERSION OF TEMPERATURENormalTemperature = 37°C = 98°F Conversion of Centigrade (Celsius) to Fahrenheit: Conversion of Fahrenheit to Centigrade (Celsius):°C = 5 ( °F ) – 32 9°F = 9 ( °C ) + 32 5
  • 160.
    Interpretation of Doctor’sOrder for DrugsThe nurse must understand the order perfectly before acting on it > The Drug> The Dose> The Route> The FrequencyIf any of the above are unclear or open for interpretations, it is the Responsibility of the nurse to clarify the order with the physician.
  • 161.
    Example: The order reads: Inderal 2 x4 a. What is the Drug? b. What is the Dose? c. What is the Route? d. What is the Frequency? e. Does this order need clarification?The order reads : Lasix 10 mg IV 1 ml O.D. a. What is the Drug? b. What is the Dose? c. What is the Route? d. What is the Frequency? e. Does this order need clarification?
  • 162.
  • 163.
    DECIMALSAll figures tothe left of the decimal point are whole numbersAll figures to the right of the decimal point are decimal fractions. 385 = . 3 8 5.385 = 385 1000tenths.38 = 38 100thousandthshundredths.3 = 3 10
  • 164.
    CHANGING FRACTIONS TODECIMALS:Fractions can be changed to decimals by dividing the numerator and the denominator¾ = 3 ÷ 4 = 0.75
  • 165.
    PERCENTAGEPercentage (% ) means hundredthsPercent ( % ) is the same as a fraction with denomination as 100. 3% = 31004510045% =
  • 166.
    CHANGING PERCENT TOA DECIMAL & CHANGING DECIMAL TO PERCENTTo change percent to a decimal, remove the percent sign and divide the number by 100 or move the decimal point two places to the left. 4% = 4/100 = .04 or 0.04To change a decimal to a percent, multiply by 100 or move the decimal point two places to the right and place % sign. 0.04 X 100 = 4% or 0.04 = 4%
  • 167.
    RATIOA Ratio consistsof two numbers as separated by a colon ( : ) e.g. 1 : 4 A ratio indicates that there is a relationship between the two numbers.A ratio is an indicated fraction. e.g. ¼ = 1 : 4The numbers in ratio must be expressed in the same terms. e.g. 3 inches : 2 feet = 3 : 24 (feet changes to inches)
  • 168.
    PROPORTIONIt is astatement showing that the two ratios have equivalent values 1 : 50 = 2 : 100If one value is not known, it can be solved by using the term X. 1 : X = 2 : 100 or meansextremes1 2X 100~
  • 169.
    THE METRIC SYSTEMItis the international decimal system of weights and measures¤ In the metric system, fractions are expressed as decimals ¤ In the decimal system, the fraction ½ is written as 0.5METRIC SYSTEMLiter = vol. of fluids milli = one thousandths Gram = weights of solids centi = one hundredths Meter = measure of length deci = one tenth mcg = one thousandths
  • 170.
    RULE OF CONVERSIONWhenconverting from a larger unit of measure to a smaller unit, multiply the larger unit by (1000, 100, 10) or move the decimal to the right.When converting a smaller unit of measure to a larger unit, divide the smaller unit by (1000, 100, 10) or move the decimal to the left.e.g. 2.5 grams = ___________ mg.
  • 171.
    APOTHECARIES SYSTEMGrain (gr) Dram Ounce Minims PoundsApproximate Equivalent Value: 1 gr = 60 mg 1 ml = 15 minims (16 minims) 1 ounce = 30 ml 1 ounce = 30 Gm 1 kg = 2.2 pounds e.g. 60 gr = _________ mg. 4 oz = _________ ml.
  • 172.
    HOUSEHOLD MEASURES 1 teaspoon(tsp) = 4 – 5 ml 1 Tablespoon (Tbsp) = 3 teaspoons (tsp) 1 Tablespoon = 15 ml 1 milliliter = 15 drops (gtts) e.g. 5 ml = ______
  • 173.
    CONVERSION OF TEMPERATURENormalTemperature = 37°C = 98°F Conversion of Centigrade (Celsius) to Fahrenheit: Conversion of Fahrenheit to Centigrade (Celsius):°C = 5 ( °F ) – 32 9°F = 9 ( °C ) + 32 5
  • 174.
    Interpretation of Doctor’sOrder for DrugsThe nurse must understand the order perfectly before acting on it > The Drug> The Dose> The Route> The FrequencyIf any of the above are unclear or open for interpretations, it is the Responsibility of the nurse to clarify the order with the physician.
  • 175.
    Example: The order reads: Inderal 2 x4 a. What is the Drug? b. What is the Dose? c. What is the Route? d. What is the Frequency? e. Does this order need clarification?The order reads : Lasix 10 mg IV 1 ml O.D. a. What is the Drug? b. What is the Dose? c. What is the Route? d. What is the Frequency? e. Does this order need clarification?
  • 176.
    GENERAL FORMULA FORDRUG CALCULATION1. Dx Q S2. Calculation by Ratio : Proportion 8 mg : x = 16 mg : 1 tab (works for any computation of Dosage if you have a given and a need to determine the unknown). Rule : 1. Units for each ratio must be the same. 2. Units for each ratio must be placed in the same order.
  • 177.
    Computation of Dosages:Whenthe dose prescribed is in milligram (mg) and the dose available is in Gram (Gm) or vice versa.E.g. The order reads : 0.008 Gm of Morphine Sulfate IV q 4 hours prn for pain. Ampule available is labeled 10 mg/ml. 1. What do you know? 0.008 Gm - 8 mg 10 mg/ml - 2. What do you need to know? Known amount in cc for 0.008 Gm dose 3. Setting up the proportion: a. the units for each ratio must be placed in the same order b. the units for each ratio must be the same ( mg to mg ) 8mg : X = 10 mg : ml
  • 178.
    4. solve forthe correct dosage 8 mg : X = 10 mg : ml 10 mg X = 8 mg/ml X = 8 mg/ml 10 mg X = .8 ml
  • 179.
    When the doseis ordered in one system and the dose on hand is in another system. E.g. The order reads : codeine sulfate ¼ gr P.O. q 8 hrs PRN for pain. Tablets on hand are labeled 0.015 Gm tablets. 1. What do you know? Known¼ gr 1 gr = 60 mg 0.015 Gm / tab 1 Gm = 1000 mg¼ = .25 2. What do you need to know? # of tablets for ¼ gr dose
  • 180.
    3. Settingup the proportion a. the units for each ratio must be the same b. the units for each ratio must be placed in the same order. .25 gm : X = 0.015 gm : 1 tab 15 mg : x = 15 mg : 1 tab 4. Solve for the correct dosage: 15 mg : x = 15 mg : 1 tab 15 mg x = 15 mg / tab x = 15 mg / tab 15 mg x = 1 tab
  • 181.
    Computation of CorrectInsulin DosageU - 40 meansU - 80 meansU - 100 meansInsulin syringes are calibrated according to the strength of insulin with which it is to be used.U 40 insulin needs a U 40 syringeU 80 insulin needs a U 80 syringe
  • 182.
    X 1 ml = ml neededIf this can not be done, the dose can be converted to millilitersDose RequiredDose on Hand Serious error can occur if incorrect syringe or incorrect b calculations are used
  • 183.
    Itis essential that all insulin be checked by a second RN to confirm that errors in dosage are not made and error in the type of insulin were not made.Fractional Dosages in Infants and Children
  • 184.
    Children’s DosesClarks’ Rule:weightof child in pounds X A.D. = child’s dose 150Body Surface Area e.g. Wt = 10 kgBSA X A.D. = child’s dose 1.7 BSA = 4(wt in kg) + 7 = BSA in m² wt in kg + 90 = 4(10 kg) + 7 = 47 10+ 90 = .47 m² Child’s dose = .47 m² X 500 1.7
  • 185.
    Youngs’ Formula:Age ofchild in Years X A.D. = Child’s dose Age of child + 12
  • 186.
    CALCULATION OF FLUIDVOLUME(BASED ON BODY WEIGHT)1. WEIGHT --- 1 – 10 kg. --- 100ml/kg. Eg. Wt = 8 kg. --- 800cc2. WEIGHT --- 11 – 20 kg.--- 1,000+50ml/excess b.wt. Eg. Wt = 15 kg. 1,000=250ml = 1,250ml 15 50-10 X 5 5 2503. WEIGHT > 20 kg. Eg. Wt = 27 kg. 1,500 + 20 ml/excess b.wt. 1,500 + 140 ml = 1640 ml. 27 20-20 X 7 7 140
  • 187.
    Calculation of IVFlow RatesCalculation of cc/hr is essential in most IV therapy. Volume # of hrs E.g. 1 L over 8 hrs = 125 cc/hr 50 cc over 20 minutes = 150 cc/hr= cc/hr
  • 188.
    Calculation of gtt/min(Long Method)STEPS : 1. Need to know cc/hr to calculate 2. Gtt factor = gtt / ml gtt factors : macrodrip 10, 15, 20 gtts/ml microdrip 60 gtt/mlEXAMPLE : LONG METHODDoctors Order : Run 1L D5W over 8 hours Microdrip - 1000 ml ÷ 8 hours = 125 cc/hr125 cc x 60 gtt/ml = 125 gtt/ml 60 min 1 10 gtt/ml set 125cc x 10 gtt/ml = 20 – 21 gtt/min 60 min 1 15 gtt/ml set 125cc x 15 gtt/ml = 31 gtt/min 60 min 1 20 gtt/ml set 125 cc x 20 gtt/ml = 41 – 42 gtt/min 60 min 1
  • 189.
    SHORT METHODcc /hr ÷ 6 for 10 gtt / min cc / hr ÷ 4 for 15 gtt / min cc / hr ÷ 3 for 20 gtt / min cc / hr = gtt / min for microdrip set
  • 190.
    SourcesFluids & Electrolytes,Lippincott Williams & WilkinsFluids & Electrolytes, Walters KluwerNelson’s Texbook of PediatricsWHO department of child and adolescent development(Medline Plus)http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/000982.htm