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   Osteoporosis is a medical condition which weakens the bones,
    making it more prone to fractures. This bone disease is believed to
    afflict eight million women and two million men in the United States
    and another 34 million of American people who have low bone
    density, which puts them at risk for the disease, according to the
    National Osteoporosis Foundation (NOF). The primary medical
    intervention for osteoporosis is Fosamax, a bisphosphonate drug. This
    medication is popular for osteoporotic individuals, considering that
    this may help in strengthening their bones and prevent the
    development of osteoporosis. However, long-term use of Fosamax is
    believed to contribute for the unusual incidences of femur fractures,
    especially post-menopausal women. Today, there arenumber of
    lawsuits filed aganst Merck & Co., manufacturer of Fosamax in
    behalf of the injured women.

      The U.S. Food and Drug Administration raised concerns about the
    potential for some serious side effects in women taking bone-
    building drugs, such as Fosamax. The FDA has announced their
    concern over the long-term use of this drug, which may potentially
    contribute to weakening the bones, thus increasing the risk of serious
    side-effects, such atypical femur fractures, esophageal cancers and
    osteonecrosis of the jaw, a painful and disfiguring crumbling of the
    jaw bone.
   Although the concerns about the long-term safety of bone drugs are
    not new, the FDA conducted its own systematic review of the
    effectiveness of bisphosphonates after years of use. The agency’s
    analysis, which found little if any benefit from the drugs after three to five
    years of use, may prompt doctors around the country to rethink how
    they prescribe them. The F.D.A. report offered little specific guidance
    about long-term use, saying that the decision to continue or stop
    treatment should be based on an individual assessment of risks, benefits
    and preferences discussed between a patient and her doctor.

   It is always essential to take care of our bones. Eating a healthy diet rich
    in calcium, magnesium and vitamin C and performing weight-bearing
    exercises contributes good benefits to our bone health. If you want to
    know more, click here for related information.

References:

   pbs.org/newshour/bb/health/jan-june12/bonedensity_05-10.html
   abcnews.go.com/Health/fda-cautions-long-term-bone-drugs-
    osteoporosis/story?id=16321946
   well.blogs.nytimes.com/2012/05/09/new-cautions-about-long-term-use-
    of-bone-drugs/
   bloomberg.com/news/2012-05-10/bone-drugs-may-not-help-women-
    long-term-fda-review-says.html

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Fda doubts benefits from long term fosamax use

  • 1.
  • 2. Osteoporosis is a medical condition which weakens the bones, making it more prone to fractures. This bone disease is believed to afflict eight million women and two million men in the United States and another 34 million of American people who have low bone density, which puts them at risk for the disease, according to the National Osteoporosis Foundation (NOF). The primary medical intervention for osteoporosis is Fosamax, a bisphosphonate drug. This medication is popular for osteoporotic individuals, considering that this may help in strengthening their bones and prevent the development of osteoporosis. However, long-term use of Fosamax is believed to contribute for the unusual incidences of femur fractures, especially post-menopausal women. Today, there arenumber of lawsuits filed aganst Merck & Co., manufacturer of Fosamax in behalf of the injured women. The U.S. Food and Drug Administration raised concerns about the potential for some serious side effects in women taking bone- building drugs, such as Fosamax. The FDA has announced their concern over the long-term use of this drug, which may potentially contribute to weakening the bones, thus increasing the risk of serious side-effects, such atypical femur fractures, esophageal cancers and osteonecrosis of the jaw, a painful and disfiguring crumbling of the jaw bone.
  • 3. Although the concerns about the long-term safety of bone drugs are not new, the FDA conducted its own systematic review of the effectiveness of bisphosphonates after years of use. The agency’s analysis, which found little if any benefit from the drugs after three to five years of use, may prompt doctors around the country to rethink how they prescribe them. The F.D.A. report offered little specific guidance about long-term use, saying that the decision to continue or stop treatment should be based on an individual assessment of risks, benefits and preferences discussed between a patient and her doctor.  It is always essential to take care of our bones. Eating a healthy diet rich in calcium, magnesium and vitamin C and performing weight-bearing exercises contributes good benefits to our bone health. If you want to know more, click here for related information. References:  pbs.org/newshour/bb/health/jan-june12/bonedensity_05-10.html  abcnews.go.com/Health/fda-cautions-long-term-bone-drugs- osteoporosis/story?id=16321946  well.blogs.nytimes.com/2012/05/09/new-cautions-about-long-term-use- of-bone-drugs/  bloomberg.com/news/2012-05-10/bone-drugs-may-not-help-women- long-term-fda-review-says.html