Diabetes mellitus 2

•

1 like•70 views

The document outlines the terms and conditions for a rental agreement between a landlord and tenant for an apartment located at 123 Main St. It specifies the monthly rent amount and due date, the security deposit required, the length of the lease, rules regarding guests and pets, and responsibilities for repairs, utilities, and notices to vacate. The landlord and tenant must both sign the agreement prior to the tenant moving into the apartment.

Science

Rheumatoid arthritis. Osteoarthritis. Gout. SLE (Systemic lupus erythematosus). Scleroderma. Polymyositis. Dermatomyositis. Rheumatic fever in children. Acute rheumatic fever. Juvenile rheumatoid arthritis. Chronic rheumatic heart disease. Dermatomyositis. Podagra. Ankylosing spondyloarthritis. Psoriatic arthritis. Glucocorticosteroids. Systemic vasculitides: Wegener's granulomatosis, Churg-strauss syndrome, Polyarteritis Nodosa (PAN), Giant-cell arteritis (Temporal arteritis), Polymyalgia rheumatica, Takayasu's arteritis (Pulseless disease). Chronic rheumatic heart disease.

Diseases of the Kidney

Dinoosh De Livera

What's hot

Fluid Mechanics (Unit4) - Internal Flows by Prof. Y. H. Ahire

Hydraulic pdf

Afmc

LOGIC GATES

Physics handbook part 2

RUHULAMIN428

Business Studies Class 12th Marketing management Project- Fruit Juice

Aashpreet Giddey

Mottershed- Filter Circuits for Power Supplies

Daphne Silveira

solution to Problem 8.13,8.14,8.15,8.16 from power plant technology by MM.EL....

ijaz Ali

SOLUTION TO Problem 2.2, 2.4, 2.10, 2.11, 2.19 From power plant technology by...

ijaz Ali

EC6503 - Tlwg unit 4 notes

BEULAH Bmerlin55

Thermodynamics. chemical engineering

Mushahid Haider

O ratinho, o morango vermelho e o grande urso esfomeado

PamellaSilveira3

What's hot (12)

Fluid Mechanics (Unit4) - Internal Flows by Prof. Y. H. Ahire

Hydraulic pdf

Afmc

LOGIC GATES

Physics handbook part 2

Business Studies Class 12th Marketing management Project- Fruit Juice

Mottershed- Filter Circuits for Power Supplies

solution to Problem 8.13,8.14,8.15,8.16 from power plant technology by MM.EL....

SOLUTION TO Problem 2.2, 2.4, 2.10, 2.11, 2.19 From power plant technology by...

EC6503 - Tlwg unit 4 notes

Thermodynamics. chemical engineering

O ratinho, o morango vermelho e o grande urso esfomeado

Recently uploaded

ESR_factors_affect-clinic significance-Pathysiology.pptx

muralinath2

GBSN - Biochemistry (Unit 5) Chemistry of Lipids

Areesha Ahmad

general properties of oerganologametal.ppt

IqrimaNabilatulhusni

Lab report on liquid viscosity of glycerin

ossaicprecious19

(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...

Scintica Instrumentation

Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes. In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.

erythropoiesis-I_mechanism& clinical significance.pptx

muralinath2

Seminar of U.V. Spectroscopy by SAMIR PANDA

SAMIR PANDA

platelets- lifespan -Clot retraction-disorders.pptx

muralinath2

SCHIZOPHRENIA Disorder/ Brain Disorder.pdf

SELF-EXPLANATORY

Orion Air Quality Monitoring Systems - CWS

Columbia Weather Systems

Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...

Sérgio Sacani

Since volcanic activity was first discovered on Io from Voyager images in 1979, changes on Io’s surface have been monitored from both spacecraft and ground-based telescopes. Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images show that a plume deposit from a powerful eruption at Pillan Patera has covered part of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive optics at visible wavelengths.

Anemia_ different types_causes_ conditions

muralinath2

Hemoglobin metabolism_pathophysiology.pptx

muralinath2

Large scale production of streptomycin.pptx

Cherry

Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...

Sérgio Sacani

We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and 30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1 . Our search finds no candidates at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to infer the properties of the evolving luminosity function without binning in redshift or luminosity that marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results, and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5 from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical models for evolution of the dark matter halo mass function.

Hemostasis_importance& clinical significance.pptx

muralinath2

THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.

Sérgio Sacani

The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.

RNA INTERFERENCE: UNRAVELING GENETIC SILENCING

AADYARAJPANDEY1

Introduction: RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression. It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences. dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants. This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes. What are small ncRNAs? micro RNA (miRNA) short interfering RNA (siRNA) Properties of small non-coding RNA: Involved in silencing mRNA transcripts. Called “small” because they are usually only about 21-24 nucleotides long. Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered). Silence an mRNA by base pairing with some sequence on the mRNA. Discovery of siRNA? The first small RNA: In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the development of the worm C. elegans. Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14. Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions. Types of RNAi ( non coding RNA) MiRNA Length (23-25 nt) Trans acting Binds with target MRNA in mismatch Translation inhibition Si RNA Length 21 nt. Cis acting Bind with target Mrna in perfect complementary sequence Piwi-RNA Length ; 25 to 36 nt. Expressed in Germ Cells Regulates trnasposomes activity MECHANISM OF RNAI: First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces. Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands. The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it. THE RISC COMPLEX: RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA Unwinding of double stranded Si RNA by ATP independent Helicase Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA. DICER: endonuclease (RNase Family III) Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC) One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute ARGONAUTE PROTEIN : 1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA 2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity. MiRNA: The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .

GBSN- Microbiology (Lab 3) Gram Staining

Areesha Ahmad

Richard's aventures in two entangled wonderlands

Richard Gill

Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.