Notes

1. CPCSEA Guidelines for
Laboratory Animals
A Comprehensive Overview
Prepared by [Your Name]

2. Introduction to CPCSEA
• • CPCSEA (Committee for the Purpose of
Control and Supervision of Experiments on
Animals) is a regulatory body in India.
• • Ensures ethical treatment of animals used in
research and testing.
• • Governs the housing, maintenance,
breeding, and experimentation on laboratory
animals.

3. Animal Procurement & Transport
• • Animals must be acquired lawfully as per
CPCSEA guidelines.
• • Health screening and quarantine measures
must be followed.
• • Transportation should minimize stress and
ensure safe conditions.

4. Housing & Environmental
Conditions
• • Animals must be housed in species-
appropriate enclosures.
• • Proper ventilation, temperature control, and
lighting should be maintained.
• • Bedding should be absorbent, non-toxic, and
replaced regularly.

5. Nutrition, Water & Sanitation
• • Animals should receive a nutritionally
adequate, contamination-free diet.
• • Continuous access to potable water must be
provided.
• • Regular cleaning, waste disposal, and
emergency care should be ensured.

6. Conduct of Experiments on
Laboratory Animals
• • Every institution must have an Institutional
Animal Ethics Committee (IAEC).
• • Alternatives to animal testing should be
considered wherever possible.
• • Pain management and humane euthanasia
techniques must be used.

7. Euthanasia Methods
• • To minimize animal suffering, humane
euthanasia must be performed.
• • Approved methods include:
• - Overdose of anesthetics
• - Carbon dioxide asphyxiation
• - Cervical dislocation (for small animals, by
trained personnel)

8. Conclusion
• • CPCSEA ensures the humane and ethical
treatment of laboratory animals.
• • Institutions must strictly adhere to
guidelines for ethical research.
• • Following CPCSEA rules helps in maintaining
scientific integrity and animal welfare.