The document announces the 8th European Multidisciplinary Colorectal Cancer Congress (EMCCC) to be held on December 11-13, 2016 in Amsterdam. It provides information on registration deadlines, the scientific program including workshops on various topics related to colorectal cancer, and keynote speakers. The congress aims to facilitate multidisciplinary interaction and discussion among researchers and clinicians from different areas involved in colorectal cancer.

1. 8th
European Multidisciplinary
Colorectal Cancer Congress
WWW.EMCCC2016.ORG
11 - 13 december 2016
RAI Amsterdam, the Netherlands
Early Bird Registration deadline: 1 July 2016
Abstract
Deadline:
1 Sept.
2016
2nd
announcement including scientific programme

2. It is our great pleasure to announce the 8th
EMCCC 2016!
The European Multidisciplinary Colorectal Cancer Congress (EMCCC) is the European conference
that truly provides a platform for in-depth multidisciplinary interaction among the various research
areas involved.The DutchColorectalCancerGroup (DCCG) has taken the initiative for the EMCCC since
2001.The conference in 2016 builds upon seven previous successful multidisciplinary conferences
on colorectal cancer which were held in the Netherlands, Germany, France and Czech Republic.
The EMCCC offers an intimate scientific/educational environment for around 700 participants.
Colorectal cancer is one of the most common types of malignancies and much progress has been made
in recent years in understanding the biology and treatment of this disease.These developments
encompass almost the full research area including genetics, biology, pathology/prognostic
markers, surgery, screening, systemic treatment, radiotherapy, and imaging.This implies that
both pre-clinical and clinical research is becoming much more multidisciplinary oriented.
The conference will have separate workshops on surgery, medical oncology, radiotherapy, pathology,
imaging, gastroenterology, and genetics, but all other sessions are plenary in order to have optimal
interaction between all disciplines.The format of the conference consists of workshops, a keynote
lecture, controversy sessions, satellite symposia, and oral and poster presentations on prevention
and screening, diagnosis and follow-up, translational research, multidisciplinary management,
genetics, evaluation of treatment, and updates on randomized CRC trials.
Looking forward meeting you in December in Amsterdam!
The EMCCC local organising committee,
Prof.dr. C.J.A. (Kees) Punt, medical oncology, congress president
Prof.dr. R.G.H. (Regina) Beets-Tan, radiology
Prof.dr. N. (Nicoline) Hoogerbrugge-van der Linden, antropogenetics
Dr. J. (Jeroen) Buijsen, radiotherapy
Prof.dr. G.A. (Gerrit) Meijer, pathology
Dr. S. (Silvia) Sanduleanu, gastroenterology
Dr. P.J. (Pieter)Tanis, surgery
Important dates
1 July 2016 Early registration deadline
1 September 2016 Abstract submission deadline
1October 2016 Abstract notifications mailed
1October 2016 Deadline regular fee
15October 2016 Abstract presenter registration deadline
1 November 2016 Deadline late breaking abstracts*
* for information on late breaking abstract requirements see www.emccc2016.org.
See the congress website for the latest information: www.emccc2016.org
The European MultidisciplinaryColorectalCancerCongres is an initiative from the DutchColorectal
CancerGroup (DCCG) en is endoserd by the following assocations:
Sponsors & Exhibitors
See pages 15 for detailed information
Congress secretariat
Congress Care
PO Box 440
NL-5201 AK ‘s-Hertogenbosch
T: +31 (0)73 690 1415
info@congresscare
www.congresscare.com
Introduction

3. CommitteesCommittees
Local Organising Committee
Prof.dr. C.J.A. (Kees) Punt, medical oncology, congress president
Prof.dr. R.G.H. (Regina) Beets-Tan, radiology
Prof.dr. N. (Nicoline) Hoogerbrugge-van der Linden, antropogenetics
Dr. J. (Jeroen) Buijsen, radiotherapy
Prof.dr. G.A. (Gerrit) Meijer, pathology
Dr. S. (Silvia) Sanduleanu, gastroenterology
Dr. P.J. (Pieter)Tanis, surgery
Scientific Committee
Surgery
P.J.Tanis (the Netherlands)
E.Tiret (France, European Society of Coloprectology)
G. Beets (the Netherlands, European Society of Digestive Oncology)
A. Martling (Sweden, European Society of Coloproctology)
D. Morton (United Kingdom, research committee ESCP)
G. Romano (Italy, UEG representative ESCP)
T. Gruenberger (Austria, ESDO)
S. Biondo (Spain, ESCP)
Medical Oncology
C.J.A. Punt (the Netherlands)
D. Arnold (Germany)
A. Sobrero (Italy)
R. Adams (UK)
T. André (France)
M. Peeters (Belgium)
H. Sorbeye (Norway)
Radiation Oncology
D. Sebag-Montefiore (United Kingdom)
C.A.M. Marijnen (the Netherlands)
K. Haustermans (Belgium)
C. Rödel (Germany)
V.Valentini (Italy)
J.P. Gérard (France)
K. Bujko (Poland)
J. Buijsen (the Netherlands)
Gastroenterology
E. Dekker (the Netherlands)
C. Rees United Kingdom)
L. Ricciardiello (Italy)
M. Bretthauer (Norway)
Imaging
R.G.H. Beets-Tan (the Netherlands)
A. Laghi (Italy)
L. Blomqvist (Sweden)
T. Helmberger (Germany)
J. Stoker (the Netherlands)
M. Stokkel (the Netherlands)
S. Halligan (United Kingdom)
P. Flamen (Belgium)
Genetics
N. Hoogerbrugge - van der Linden (the Netherlands)
G. Evans (United Kingdom)
M. Genuardi (Italy)
E. Holinky-Feder (Germany)
T. Frebourg (France)
R. Sijmons (the Netherlands)
M.Tischkowitz (United Kingdom)
Pathology
G. Meijer (the Netherlands)
Ph. Quirke (UK)

4. Sunday 11 December Monday
12 December
Tuesday
13 December
08.00 Registration Registration
08.00 - 10.00 Interactive
computerized
radiology
workshop
Interactive
computerized
radiology
workshop
08.15 Plenary session 1 Plenary session 7
09.30 Plenary session 2 Plenary session 8
10.45 Break Break
11:00 Registration 11.15 Plenary session 3 Plenary session 9
13:00 Workshop round 1 12.30 Lunch & Posters Lunch & Posters
12.45 - 13.45
Sponsored
symposium 2
Sponsored
symposium 3
14:15 Break 14:00 Key-note lecture Plenary session 10
14:45 Workshop round 2 14:45 Plenary session 4
15.15 Plenary session 5 Plenary session 11
16:00 Sponsored
symposium 1 16.00 - 16.30 Break Break
17:45 Opening 16.30 Plenary session 6 Plenary session 12
18:45 Welcome
Reception
18.00 Drinks & Posters Closing & Drinks
SUNDAY 11 DECEMBER 2016
11:00 REGISTRATION
13:00 - 14:15 Workshop round 1
13:00 - 14:15 Workshop 1: Medical Oncology - Methodology of clinical trails
13:00 Issues in the design of maintenance trials
Dirk Arnold, CUF Cancer Centre, Portugal
13:15 Toxicity analysis of clinical trials
Axel Grothey, Mayo Clinic, United States
13:30 The meaning of PFS as an endpoint
Kees Punt, University of Amsterdam, the Netherlands
13:45 Cohort multiple randomized controlled trial design
LennyVerkooijen, University Medical Centre Utrecht, the Netherlands
14:00 Discussion
13:00 - 14:15 Workshop 2: Surgical workshop -
SurgicalTreatment of Metastatic Disease
13:00 Liver resection - How extensive and how minimally invasive?
Peter Neumann, Uniklinik RWTH Aachen, Germany
13:15 State of the art treatment of peritoneal carcinomatosis
Pompiliu Piso, University Hospital of Regensburg, Germany
13:30 Surgery for extrahepatic visceral metastases
KeesVerhoef, Radboud University Medical Centre, the Netherlands
13:45 Discussion
13:00 - 14:15 Workshop 3: Radiation Oncology workshop -
The role a local boost in the treatment of rectal cancer
13:00 Dose-response curves, brachy and external boost
Ane Appelt, Rigshospitalet Vejle Hospital, Denmark
13:15 Intraluminal contact therapy
Sun Myint, Clatterbridge Cancer Centre, United Kingdom
13:30 Trial external beam radiation
Peter Burbach, University Medical Centre Utrecht, the Netherlands
13:45 Discussion
13:00 - 14:15 Workshop 4: Pathology workshop
13:00 DNA, stroma profiles
Instituut Erik Hooijberg,VU University Medical Centre, the Netherlands
13:20 Scoring tumor infiltrate
Petur Snaebjornsson, Netherlands Cancer Institute, the Netherlands
13:40 Discussion
Programme at glance Scientific Programme

5. 13:00 - 14:15 Workshop 5: Genetics workshop 1
13:00 Microbioma and risk for CRC in Lynch syndrome
Annemarie Boleij, Radboud University Medical Centre, the Netherlands
13:10 Testing for Lynch syndrome and other predisposition variants –
a medical oncology perspective
David Church, University of Oxford, United Kingdom
13:20 New guidelines on genetic testing in CRC
T.b.a.
13:30 New genes for adenomatous polyposis and predisposition to CRC
Roland Kuiper, Radboud University Medical Centre, the Netherlands
13:40 Serrated Polyposis
Thomas Huw, Imperial College London, United Kingdom
13:50 Discussion
13:00 - 14:15 Workshop6:ImagingworkshopColonandRectalCancerImaging
13:00 Local Staging Colon Cancer : CT and MRI
Max Lahaye, Netherlands Cancer Institute, the Netherlands
13:15 MR imaging
Doenja Lambregts, Maastricht University Medical Centre, the Netherlands
13:30 Endorectal ultrasonography and elastography evaluation of rectal tumors
JoWaage, Haukeland University Hospital, Norway
13:45 Distant staging of CRC : Optimal algorithm
Christoph Zech, Basel University hospital, Switzerland
14:00 Discussion
14:15 BREAK
14:45 - 16:00 Workshops round 2
RepeatWorkshop 1
RepeatWorkshop 2
RepeatWorkshop 3
RepeatWorkshop 4
RepeatWorkshop 5
RepeatWorkshop 6
16:00 - 17:30 Sponsored symposium
See page 15 for detailed information
17:45 OPENING
18:00 WELCOME RECEPTION
MONDAY 12 DECEMBER 2016
08:00 REGISTRATION
08:00 - 10:00 Interactive computerized radiology workshop
08:15 - 09:30 Session 1: Follow-up
08:15 New data uit PROFILES registry
Lonneke van de Poll-Franse,Tilburg University, the Netherlands
08:40 Frequency of surveillance
T.b.a.
09:05 CEAWatch trial
CharlotteVerberne, University Medical Centre Groningen, the Netherlands
09:30 - 10:45 Session 2: Health economics and quality of care
09:30 Magnitude of clinical benefit of colorectal cancer drugs
T.b.a.
09:55 Variations in patterns of CRC care - which lessons can be learned?
T.b.a.
10:20 Long term surgical morbidity and reintervention after rectal cancer treatment;
a snapshot population based analysis
PieterTanis, Academic Medical Centre, the Netherlands
10:45 BREAK
11:15 - 12:30 Session 3: Updated results from phase 3 trials
11:15 The FACS trial: the role of CT and CEA in colorectal cancer follow up
John Primrose, Southampton General Hospital, United Kingdom
11:30 CREST trial (stent as bridge to surgery versus acute resection)
James Hill, University of Colorado Health Sciences Centre, United States
11:45 The German CAO/ARO/AIO-04 study
Claus Rodel, University of Frankfurt, Germany
12:00 Translational research CAIRO3 study
Miriam Koopman, University Medical Centre Utrecht, the Netherlands
12:15 New EPOC trial
John Primrose, Southampton General Hospital, United Kingdom
12:30 LUNCH POSTERS
Scientific ProgrammeScientific Programme

6. 12:45 - 13:45 Sponsored Symposium 2
See page 15 for detailed information
14:00 - 14:45 Key-note lecture:The genomic landscape of colorectal cancer
T.b.a.
14:45 - 15:15 Session 4:Translational research
14:45 Radiomics: there is more than meets the eye
Philippe lambin, MAASTRO clinic, the Netherlands
15:00 Relation tumor and stroma
Onno Kranenburg, University Medical Centre Utrecht, the Netherlands
15:15 - 16:00 Session 5: Controversy 1
15:15 PRO || Oxaliplatin has a role in the (neo)adjuvant treatment of locally advanced
rectal cancer
Dirk Arnold, CUF Cancer Centre, Portugal
15:30 CON || Oxaliplatin has a role in the (neo)adjuvant treatment of locally advanced
rectal cancer
David Sebag-Montefiore, University of Leeds, United Kingdom
15:45 - 16:00 Discussion
16:00 BREAK
16:30 - 17:50 Session 6: Multidisciplinary management 1
16:30 Whole body imaging for detection of distant metastases: what’s new?
VincentVandecaveye, University Hospitals Leuven, Belgium
16:50 Treatment of screen detected early colon and rectal cancers
Roel Hompes, University of Oxford, United Kingdom
17:10 Anti-VEGF versus anti-EGFR antibodies in RAS wildtype metastatic CRC: what
are the data?
Axel Grothey, Mayo Clinic, United States
17:30 Role of SIRT in the management of CRC liver metastases
Thomas Helmberger, Institute for Diagnostic and Interventional Radiology
München, Germany
18:00 DRINKS POSTERS
TUESDAY 13 DECEMBER 2016
08:00 REGISTRATION
08:00 - 10:00 Interactive computerized radiology workshop
08:15 - 09:30 Session 7: Prevention and screening
08:15 Taiwan: data from the nationwide CRC screening programme
(10 years experience)
Chiu Han-Mo, NationalTaiwan University Hospital,Taiwan
08:40 Screening uptake and socioeconomic status
T.b.a.
09:05 Biomarker tests for screening of colorectal cancer:What is on the horizon?
Gerrit Meijer, Netherlands Cancer Institute, the Netherlands
09:30 - 10:45 Session 8: Genetics
09:30 Germline genetic testing form targeted testing to panel testing
Maurizio Genuardi, University of the Sacred Heart, Italy
09:45 Genetic risk communication in daily practice
Jan Oosterwijk, University Medical Centre Groningen, the Netherlands
10:00 Adding a family history to population CRC screening
Nicoline Hoogerbrugge, Radboud University Medical Centre, the Netherlands
10:15 NGS in germline or somatic testing
T.b.a.
10:30 Characterization of unclassified MMR gene variants
Hein te Riele, Netherlands Cancer Institute, the Netherlands
10:45 BREAK
11:15 - 12:30 Session 9: Colorectal cancer and the immune system
11:15 Principles of immunotherapy
Erik Hooijberg,VU university medical cente, the Netherlands
11:45 Current status and future prospects of immunotherapy in colorectal cancer
T.b.a.
12:30 LUNCH POSTERS
12:45 - 13:45 Sponsored Symposium 2
See page 15 for detailed information
Scientific ProgrammeScientific Programme

7. Scientific Programme
14:00 - 15:15 Session 10: Rectal cancer surgery
14:00 A patient tailored approach to low rectal cancer
Yves Panis, Hôspital Beaujon Paris, France
14:25 Is there still an oncological safety issue in laparoscopic rectal cancer surgery?
T.b.a.
14:25 TransanalTME as the step forward in minimally invasive rectal cancer surgery
JurriaanTuynman,VU university medical cente, the Netherlands
15:15 - 16:00 Session 11: Controversy 2
15:15 PRO ||Wait and see after clinical complete response following
chemoradiotherapy for rectal cancer is an acknowledged treatment option
Geerard Beets, Netherlands Cancer Institute, the Netherlands
15:15 CON ||Wait and see after clinical complete response following
chemoradiotherapy for rectal cancer is an acknowledged treatment option
Rob Glynne-Jones, MountVernon Cancer Centre, United Kingdom
15:40 PRO || Improving complete responders of chemo-radiotherapy, role of systamic
therapy
Julio Garcia Aguilar, Memorial Sloan Kettering Cancer Cente, United States
15:40 CON || Improving complete responders of chemo-radiotherapy, role of
systamic therapy
VincenzoValentini, Catholic University of the Sacred Heart, Italy
16:00 BREAK
16:30 - 17:50 Session 12: Interval colorectal cancer: from nomenclature to
benchmarking
16:30 Interval CRC:What andWhy?
Silvia Sanduleanu, Maastricht University Medical Centre, the Netherlands
16:50 Interval cancer after colonoscopy - data from the Bowel Cancer Screening
Program
Matthew Rutter, NHS FoundationTrust, United Kingdom
17:10 Interval cancers: Can we avoid them?
Chiu Han-Mo, NationalTaiwan University Hospital,Taiwan
17:30 The molecular secrets of interval cancers
Beatriz Carvalho, Netherlands Cancer Institute, the Netherlands
18:00 CLOSING DRINKS
Abstract deadline
Thursday 1 September 2016, 10.00hrs. CET (Central EuropeanTime)
The EMCCC Scientific Committee would like to encourage authors to submit their abstracts
through the congress website.The online submission module is available at: www.emccc2016.org.
Please check the conference website for the submission guidelines and read them carefully before
submitting your abstract.
Late breaker abstracts
Late breaker abstracts will only be considered if there is new information on surgery, medical
oncology, radiotherapy, pathology, imaging, gasttoenterology, and genetics that should be
brought to the attention of conference because it is timely and will likely have an impact on the
conference topics and the CRC community at large. Late breaking abstracts can be sent until
1 November 2016. Information on submission will be published as of 1 October 2016.
Important dates for authors
1 September 2016 Abstract submission deadline
1 October 2016 Abstract notifications mailed
15 October 2016 Abstract presenter registration deadline
1 November 2016 Deadline late breaking abstracts
Registration
Registration fees
Early Bird Regular Late
(until 1 July ‘16) (2 July -1 October ‘16) (as of 2 October ‘16)
Physicians academics EUR 475 EUR 675 EUR 795
Physicians academics in training EUR 295 EUR 395 EUR 495
Emerging economy rate EUR 175 EUR 200 EUR 200
What is included in the registration fee?
The registration fee for delegates includes: admission to the meeting, welcome reception,
programme and abstract book, e-certificate of attendance, 2 lunches and all coffee breaks.
Congress dinner Monday
Dinner tickets are available at the price of EUR 75.
Please make your reservation when you register online.
* Please check the website www.emccc2016.org for terms and conditions of registration.
Registration payment
Registration is possible via the congress website. Payment can be done online
(all regular credit cards and SEPA direct debit).
Group registrations
For group registrations please contact the congress secretariat via: info@congresscare.com.
Group registration is available for groups of 5 participants or more.
Call for abstracts / RegistrationScientific Programme

8. CME Accreditation
Accreditation is applied for at the EuropeanAccreditationCouncil forContinuing Medical Education
(EACCME). This accreditation will be endorsed by the European Union of Medical Specialists
(UEMS) ensuring that the CME credits awarded to the participants are recognized by the national
medical authorities who have agreed to co-operate in this European system. EACCME credits are
recognized by theAmerican MedicalAssociation towards the Physician’s RecognitionAward (PRA).
Venue
The congress will be held in the RAI Congress Centre, Amsterdam, the Netherlands. www.rai.nl
Exhibition sponsored symposia
A targeted group of biotechnical and pharmaceutical companies will be invited to organize a
sponsored integrated symposium and or exhibit their products and services.
Language
The official congress language will be English. No simultaneous translation will be available.
Letter of invitation
The organizers will be pleased to send a letter of invitation to any individual requesting one, once
their registration form and fee have been received. It is to be understood that such an invitation is
intended to help potential participants raise travel funds or obtain a visa. It is not a commitment on
the part of the congress to provide any financial support. Applications have to be received by the
conference secretariat before 1 October 2016. A refused visa application is no reason for refund.
Insurance
In registering for the EMCCC2016 delegates agree that neither the organization nor the congress
agency Congress Care is responsible for individual medical, travel or personal insurance. Delegates
are requested to arrange their own travel and health insurance. The organizers cannot assume
liability for changes in the programme due to external circumstances.
Website
Please check de website www.emccc2016.org for more relevant information and (programme)
updates.
Sunday 11 December 2016
16:00 Sponsored symposium 1 Organised by Servier
Monday 12 December 2016
12:45 Sponsored symposium 2
Tuesday 13 December 2016
12:45 Sponsored symposium 3
Sponsors EMCCC 2016
Major sponsors
Sponsors
General information Integrated Sponsored Symposia

9. Congress secretariat
Congress Care
PO Box 440
NL-5201 AK ‘s-Hertogenbosch
T: +31 (0)73 690 1415
info@congresscare
www.congresscare.com
WWW.EMCCC2016.ORG