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Lesion size, Etiology and algorithmic approaches to
CHONDRAL LESIONS
Dr.RAJAT JANGIR
Professor
Mahatma Gandhi Hospital, Jaipur
IDEAL CARTILAGE PROCEDURE
CHASING THE HOLY GRAIL
DECISION MAKING IS NOT LINEAR
SYMPTOMS
CARTILAGE
INJURY
MENISCUS
TEAR
SUBCHONDRAL
BONE LESIONS
LIAGMENT
INJURY
MALALIGNMENT
No reliable correlation between
Clinical symptoms and Articular cartilage status
Etiology
• Trauma – most common
• OCD
• Osteonecrosis
Focal
• Osteoarthritis – most common
• Ligament instability
• Meniscus deficiency
Degenerative
Patient-centered Approach
Patients Symptoms
Concomitant knee pathology
Correlation of Imaging findings
Intraarticular and subchondral findings
Goals and expectations
Patient-centered Evaluation
• History
• Risk factors Age Sex BMI
• Alignment
• Instability
• Locking
Symptoms will not always represent the degree of cartilage damage
Patient-centered Evaluation
Performance demand
Return to Sports
Return to ADL
Prophylactic treatment for the expectation of disease progression at the
initial onset of symptoms is not recommended – unpredictable nature
Imaging
• Xray Weight-bearing AP
• Flexion PA view
Tibiofemoral
joint
• Lateral View
• Merchant view
PF joint
Standing full-length scanogram
MRI
Cartilage Meniscus Ligament Subchondral Bone
Identification, Sizing, Characterization, of focal
chondral lesion
2D Fat Suppressant and 3D Fast Spin ECHO
DEPENDENCE ON MRI IS NOT JUSTIFIED
36 % Full thickness lesions
Arthroscopy – Gold Standard
Non Surgical Care
The benefits of exercise overweighs and insufficient evidence
that activity increases the progression
Physical activity and dedicated rehab
Symptoms relief Not Cartilage repair
USE ORTHOBIOLOGICS JUDICIOUSLY
Paucity of high quality studies
Preliminary results are encouraging
Not enough to recommend routine use at this time
Criteria For Surgery
Unacceptable Pain and dysfunction
Concomitant Pathology Considered
Nonsurgical treatment considered
Risk-Benefit ratio for Patients Goals
SYMPTOMATIC TIBIOFEMORAL CHONDRAL LESION
PF- TTO TF-DFO/HTO
MALALIGNMENT
REPAIR TRANSPLANT
LIGAMANT RECONSTRUCTION
MENISCUS
INSTABILITY
Correct All comorbidities at Some Point along the treatment Continuum
ALIGNMENT
MENISCAL
DEFICIENCY
INSTABILITY
SC SC
<2-3 CM2
LOW DEMAND
DEBRIDEMENT
MF +ADJUNCT*
HIGH DEMAND
DEBRIDEMENT
MF +ADJUNCT*
OCT
OAG
>2-3 CM2
LOW DEMAND
DEBRIDEMENT
MF +ADJUNCT*
OCT
OAG
ACI *
HIGH DEMAND
OAG
ACI*
Size
*Suchondral Bone Normal
Femoral MF OCT ACI OAG
PF Joint Topographical
Challenges for OCT
Tibial
Geometry
Poor Access
Little evidence
Location
There is More Than One Right Answer
FIBR0US
EASIER
HYALINE
COMPLEX
DBR MF OATS MACI OAG
DEBRIDEMENT IS AN ACCEPTABLE FORM OF TREATMENT
51.9
9.3
38.8
SYMPTOMATIC
RELIEF
INSURANCE DENIAL OTHERS
Microfracture and its adjuncts have evolved and remain
a cost-effective first-line treatment strategy
OCT remains a durable and predictable graft option in
smaller lesions (<2 cm2) in the young and active patient population.
• Large chondral lesions (≥3 cm2)
• OAG, MACI
• Both mid-term and long-term favourable results
Paucity of high quality studies
Preliminary results are encouraging
A lot of on going research
High-Grade Cartilage Defects in Young Active Patients
Treatment Advantages Disadvantages
MF Inexpensive
works well on small defects
relief tends to decline over time
worse results with larger defects
OCT Inexpensive
excellent option for defects 2 cm2 in athletes
Cannot be used on larger defects
donor-site morbidity
OAG Fast rehabilitation
varying size and subchondral bone involvement
athletes with large defects who cannot commit to long recovery
Expensive
availability
limited options for revision
ACI Durable symptom relief
superior clinical improvement VS MF
can treat large defects
Expensive
2-stage operation
long rehabilitation
Manage Expectations: Know the literature and know your own experience
NON OPERATIVE SUCCESSFUL OUTCOME POOR OUTCOME
CAREFUL PATIENT SELECTION IS THE KEY
Thank You

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Cartilage lesiosns - insight in management

  • 1. Lesion size, Etiology and algorithmic approaches to CHONDRAL LESIONS Dr.RAJAT JANGIR Professor Mahatma Gandhi Hospital, Jaipur
  • 3. DECISION MAKING IS NOT LINEAR SYMPTOMS CARTILAGE INJURY MENISCUS TEAR SUBCHONDRAL BONE LESIONS LIAGMENT INJURY MALALIGNMENT No reliable correlation between Clinical symptoms and Articular cartilage status
  • 4. Etiology • Trauma – most common • OCD • Osteonecrosis Focal • Osteoarthritis – most common • Ligament instability • Meniscus deficiency Degenerative
  • 5. Patient-centered Approach Patients Symptoms Concomitant knee pathology Correlation of Imaging findings Intraarticular and subchondral findings Goals and expectations
  • 6. Patient-centered Evaluation • History • Risk factors Age Sex BMI • Alignment • Instability • Locking Symptoms will not always represent the degree of cartilage damage
  • 7. Patient-centered Evaluation Performance demand Return to Sports Return to ADL Prophylactic treatment for the expectation of disease progression at the initial onset of symptoms is not recommended – unpredictable nature
  • 8. Imaging • Xray Weight-bearing AP • Flexion PA view Tibiofemoral joint • Lateral View • Merchant view PF joint Standing full-length scanogram
  • 9. MRI Cartilage Meniscus Ligament Subchondral Bone Identification, Sizing, Characterization, of focal chondral lesion 2D Fat Suppressant and 3D Fast Spin ECHO
  • 10. DEPENDENCE ON MRI IS NOT JUSTIFIED 36 % Full thickness lesions
  • 12. Non Surgical Care The benefits of exercise overweighs and insufficient evidence that activity increases the progression Physical activity and dedicated rehab Symptoms relief Not Cartilage repair
  • 13. USE ORTHOBIOLOGICS JUDICIOUSLY Paucity of high quality studies Preliminary results are encouraging Not enough to recommend routine use at this time
  • 14. Criteria For Surgery Unacceptable Pain and dysfunction Concomitant Pathology Considered Nonsurgical treatment considered Risk-Benefit ratio for Patients Goals
  • 15. SYMPTOMATIC TIBIOFEMORAL CHONDRAL LESION PF- TTO TF-DFO/HTO MALALIGNMENT REPAIR TRANSPLANT LIGAMANT RECONSTRUCTION MENISCUS INSTABILITY
  • 16. Correct All comorbidities at Some Point along the treatment Continuum ALIGNMENT MENISCAL DEFICIENCY INSTABILITY SC SC
  • 17. <2-3 CM2 LOW DEMAND DEBRIDEMENT MF +ADJUNCT* HIGH DEMAND DEBRIDEMENT MF +ADJUNCT* OCT OAG >2-3 CM2 LOW DEMAND DEBRIDEMENT MF +ADJUNCT* OCT OAG ACI * HIGH DEMAND OAG ACI* Size *Suchondral Bone Normal
  • 18. Femoral MF OCT ACI OAG PF Joint Topographical Challenges for OCT Tibial Geometry Poor Access Little evidence Location
  • 19. There is More Than One Right Answer FIBR0US EASIER HYALINE COMPLEX DBR MF OATS MACI OAG
  • 20. DEBRIDEMENT IS AN ACCEPTABLE FORM OF TREATMENT 51.9 9.3 38.8 SYMPTOMATIC RELIEF INSURANCE DENIAL OTHERS
  • 21. Microfracture and its adjuncts have evolved and remain a cost-effective first-line treatment strategy
  • 22. OCT remains a durable and predictable graft option in smaller lesions (<2 cm2) in the young and active patient population.
  • 23. • Large chondral lesions (≥3 cm2) • OAG, MACI • Both mid-term and long-term favourable results
  • 24. Paucity of high quality studies Preliminary results are encouraging A lot of on going research
  • 25. High-Grade Cartilage Defects in Young Active Patients Treatment Advantages Disadvantages MF Inexpensive works well on small defects relief tends to decline over time worse results with larger defects OCT Inexpensive excellent option for defects 2 cm2 in athletes Cannot be used on larger defects donor-site morbidity OAG Fast rehabilitation varying size and subchondral bone involvement athletes with large defects who cannot commit to long recovery Expensive availability limited options for revision ACI Durable symptom relief superior clinical improvement VS MF can treat large defects Expensive 2-stage operation long rehabilitation
  • 26. Manage Expectations: Know the literature and know your own experience NON OPERATIVE SUCCESSFUL OUTCOME POOR OUTCOME CAREFUL PATIENT SELECTION IS THE KEY