Cartilage lesions - insight in management
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3. DECISION MAKING IS NOT LINEAR
SYMPTOMS
CARTILAGE
INJURY
MENISCUS
TEAR
SUBCHONDRAL
BONE LESIONS
LIAGMENT
INJURY
MALALIGNMENT
No reliable correlation between
Clinical symptoms and Articular cartilage status
4. Etiology
• Trauma – most common
• OCD
• Osteonecrosis
Focal
• Osteoarthritis – most common
• Ligament instability
• Meniscus deficiency
Degenerative
6. Patient-centered Evaluation
• History
• Risk factors Age Sex BMI
• Alignment
• Instability
• Locking
Symptoms will not always represent the degree of cartilage damage
7. Patient-centered Evaluation
Performance demand
Return to Sports
Return to ADL
Prophylactic treatment for the expectation of disease progression at the
initial onset of symptoms is not recommended – unpredictable nature
9. MRI
Cartilage Meniscus Ligament Subchondral Bone
Identification, Sizing, Characterization, of focal
chondral lesion
2D Fat Suppressant and 3D Fast Spin ECHO
12. Non Surgical Care
The benefits of exercise overweighs and insufficient evidence
that activity increases the progression
Physical activity and dedicated rehab
Symptoms relief Not Cartilage repair
14. Criteria For Surgery
Unacceptable Pain and dysfunction
Concomitant Pathology Considered
Nonsurgical treatment considered
Risk-Benefit ratio for Patients Goals
16. Correct All comorbidities at Some Point along the treatment Continuum
ALIGNMENT
MENISCAL
DEFICIENCY
INSTABILITY
SC SC
17. <2-3 CM2
LOW DEMAND
DEBRIDEMENT
MF +ADJUNCT*
HIGH DEMAND
DEBRIDEMENT
MF +ADJUNCT*
OCT
OAG
>2-3 CM2
LOW DEMAND
DEBRIDEMENT
MF +ADJUNCT*
OCT
OAG
ACI *
HIGH DEMAND
OAG
ACI*
Size
*Suchondral Bone Normal
18. Femoral MF OCT ACI OAG
PF Joint Topographical
Challenges for OCT
Tibial
Geometry
Poor Access
Little evidence
Location
19. There is More Than One Right Answer
FIBR0US
EASIER
HYALINE
COMPLEX
DBR MF OATS MACI OAG
20. DEBRIDEMENT IS AN ACCEPTABLE FORM OF TREATMENT
51.9
9.3
38.8
SYMPTOMATIC
RELIEF
INSURANCE DENIAL OTHERS
21. Microfracture and its adjuncts have evolved and remain
a cost-effective first-line treatment strategy
22. OCT remains a durable and predictable graft option in
smaller lesions (<2 cm2) in the young and active patient population.
23. • Large chondral lesions (≥3 cm2)
• OAG, MACI
• Both mid-term and long-term favourable results
24. Paucity of high quality studies
Preliminary results are encouraging
A lot of on going research
25. High-Grade Cartilage Defects in Young Active Patients
Treatment Advantages Disadvantages
MF Inexpensive
works well on small defects
relief tends to decline over time
worse results with larger defects
OCT Inexpensive
excellent option for defects 2 cm2 in athletes
Cannot be used on larger defects
donor-site morbidity
OAG Fast rehabilitation
varying size and subchondral bone involvement
athletes with large defects who cannot commit to long recovery
Expensive
availability
limited options for revision
ACI Durable symptom relief
superior clinical improvement VS MF
can treat large defects
Expensive
2-stage operation
long rehabilitation
26. Manage Expectations: Know the literature and know your own experience
NON OPERATIVE SUCCESSFUL OUTCOME POOR OUTCOME
CAREFUL PATIENT SELECTION IS THE KEY