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1. Bioinformatics
Conference 2010
Enhancing synergy among life sciences and information technology
17th – 18th May 2010, BSG House, London, UK BOOK NOW!
Key Speakers
Josef Scheiber, Computational Biologist, Roche Diagnostics
Dr. Bhushan Bonde, Principal Scientist (Bioinformatics), GlaxoSmithKline
Dr. Adel Laoui, Director, Healthcare Technologies Aging Therapeutic Strategic Unit, Sanofi Aventis
Christopher Southan, Contractor, AstraZeneca
Dr. Jonathan Green, Head of Bioinformatics Unit, Health Protection Agency
Sandeep Modi, Cheminformatics, Unilever
Chris Rawlings, Head of Biomathematics and Bioinformatics, Rothamsted Research
Dr. Tatiana Tatarinova, Senior Lecturer Statistics, University of Glamorgan
Rob Gill, Director, AnurOS
Dr. Florian Markowetz, Group Leader, Computational Biology, Cancer Research UK Cambridge Research Institute
Driving the Industry Forward | www.futurepharmaus.com
Media Partners Organised By
To Book Call: +44 (0) 20 7336 6100 | www.visiongain.com/bioinformatics

2. Conference Introduction
Bioinformatics Conference 2010
17th – 18th May 2010, London, UK
Dear Colleague, Media Partners:
According to BCC Research ‘The worldwide value of bioinformatics is expected to PharmiWeb.com is the leading industry-sponsored portal for
grow to $3.0 billion in 2010, at an average annual growth rate of 15.8%.’ the pharmaceutical sector. Supported by most of the leading
pharmaceutical corporations, PharmiWeb.com provides dynamic real-time news, features,
In recent years there has been an explosive growth in biological data which has events listings and international jobs to industry professionals across Europe and the US.
to be managed and stored for various purposes. Bioinformatics plays a vital role in
developing new tools for managing and analysing the data. For further information please email: corporate@pharmiweb.com
BIOTECHNOLOGY EUROPE is owned by BIOTECHNOLOGY WORLD.
The bioinformatics market is driven by the need of pharmaceutical and biotechnology
It is based and located in Warsaw, Poland. Biotechnology World was
companies to increase the efficiency of their drug-discovery and development
efforts. The focus is now on target validation for translating genomic information founded in 2007 to provide the world’s biotech and pharma information and market to
into knowledge for developing therapeutics, proteomics and the changing trends in make it universally accessible and useful for scientific and business processes. Its first step
the drug discovery procedures. to fulfilling that mission was building the BIOTECHNOLOGY EUROPE platform that will
allow a quick spread of information in different channels. BIOTECHNOLOGY EUROPE offers
By attending this conference you will be a key participant to discuss the practical companies completed internet public relations, publication and marketing solutions. One of
challenges encountered and assess latest scientific results with fellow researchers, the mains goals of BIOTECHNOLOGY EUROPE is to integrate the Biotech and Pharma Sector
practitioners, developers, scientists on all aspects of bioinformatics which will in Europe to global biotechnology, pharmaceutical and life science activities.
facilitate to establish business or research partnership for future alliances.
For further information please visit www.biotechnology-europe.com
Visiongains’s bioinformatics conference will provide an ideal platform for the Future Pharmaceuticals has forged powerful relationships with
Driving the Industry Forward | www.futurepharmaus.com
attendees to get an overview of the recent advances and challenges in this area key industry leaders to provide a platform for successful brand
and provide a novel outlook on emerging technologies and next generation business recognition, and for senior decision-makers to have the means to procure and plan
models. implementation strategies based on the topics covered. Positioned to be an authoritative
resource within top pharma companies as well as small, specialty, and biotech, Future
Key Benefits: Pharmaceuticals magazine is geared to create a deep penetration into a highly targeted
• Examine DNA and RNA structure, function and sequence analysis and responsive audience, bridging the gap between the industries’ top issues and the
• Assess the challenges of data integration solutions top-tier vendors can provide.
• Evaluate the advantages of proteomic analysis to the drug industry For further information please visit: www.futurepharmaus.com
• Analyse the future regulatory environment InPharm is the online platform for exclusive pharmaceutical news,
• Receive an update on the global informatics software market comment, contracts, services, jobs and events and is home to
InPharmjobs.com, Pharmafile and Pharmafocus.
• Gain an insight into the bioinformatics application in drug discovery
• Discover the effects of gene methylation in biological systems
For further information please visit: www.In-Pharm.com
• Understand the role of informatics to enable a consumer healthcare business ‘Pharma Connections Worldwide® is the leading professional
model business networking website focused in the Pharmaceutical,
Biotechnology and Life Sciences research industry. Our goal is to provide a conduit for
• Get an overview of available genomic resources and systems biology platforms delivery of premiere content coupled with the right clientele in order to facilitate business
• Be part of a unique networking opportunity development opportunities among industry professionals responsible for making key
decisions in a global marketplace. ‘
Best regards
For further information please visit: www.pharmaconnections.com
Pranita Nangia About Visiongain:
Conference Producer Visiongain is a specialist business information company focused on providing cutting edge
products and services across the Pharmaceutical/Biotech, Telecommunications, Defence
and Finance sectors, which include reports, conferences, online daily news and offline
Who should attend? • Drug Safety news analysis and bespoke consultancy. With a commitment to innovation and excellence,
VPs, Directors, Heads and • Regulatory Affairs visiongain offers flexible solutions to meet our clients’ business intelligence needs, providing
Managers of: • Scientific Affairs the right information at the right time to facilitate the commercial decision-making process. Our
pharmaceutical products include Pharma Business Daily, the leading daily email newsletter for
• Health Informatics • Legal the pharmaceutical, biotech and healthcare industries, and a range of independent, high-quality,
• Medical Informatics • Intellectual Property in-depth reports covering focused and topical areas of concern. Our pharmaceutical conferences
• Process Development address the hottest commercial, regulatory and technical topics and provide an ideal forum for
• Bioinformatics
debate and networking for pharmaceutical professionals from around the world.
• Biostatistics • Process Engineering
For further information, please visit: www.visiongain.com
• Biocomputing • Validation
• Bio Research • Technical Management
• Bio IT • Pharmaceutical Sponsorship and exhibition opportunities:
Technology This event offers a unique opportunity to meet and do business with some of the key
• Clinical Trial
• Analytical Research, players in the pharmaceutical and biotech industries. If you have a service or product to
• Scientific Data promote, you can do so at this event by:
Scientist,
• Bioanalytical
• Marketing • Hosting a networking drinks reception
• Chemoinformatics • Taking an exhibition space at the conference
• Sales
• Lead Discovery • Advertising in the delegate documentation pack
• Product Management • Providing branded bags, pens, gifts, etc.
• Genetics
• Business Development If you would like more information on the range of sponsorship or exhibition possibilities
• Biochemistry for visiongain's Immunogenicity Summit, please contact us:
Others
• Computational Chemistry
• Scientists Avnee Gajjar, +44 (0)20 7549 9948
• Computer Assisted avnee.gajjar@visiongainglobal.com
Drug Design • Biologists
Ronald Magali, +44 (0)20 7549 9934
• Data Mining • Physicists
ronald.magali@visiongainglobal.com
• Molecular biology • Academics
James Hopkins, +44 (0)20 7549 9974
• Molecular Medicine • Researchers james.hopkins@visiongainglobal.co.uk

3. Day 1
Bioinformatics Conference 2010
Monday 17th May 2010, London, UK
09:30 Registration and refreshments 13:10 Networking lunch
14:30 An integrated approach for the functional analysis
10:00 Opening address from the chair
of gene expression data
• Overview of available genomic resources and systems biology platforms
10:10 Analysing networks in biology – What data do we • Strategy of a functional integrative approach
need for sophisticated analyses and why?
• Application to identification/validation of biomarkers in cancer
• Properties of biological networks
Dr Nicolas Goffard
• Overview on information we need Bioinformatician - Functional Analysis
• Overview on available information Almac Diagnostics
• What can we do with that?
• Examples 15:10 From phenotypes to pathways: inferring genetic
• Future directions architecture from perturbation maps
Josef Scheiber • High-throughput gene perturbation screens
Computational Biologist
Roche Diagnostics • Exploratory analysis: enriched gene sets and sub-networks
• Reconstructing pathways from transcriptional phenotypes
10:50 Assess the challenges of data integration Dr. Florian Markowetz
• Importance of data integration Group Leader, Computational Biology
Cancer Research UK Cambridge Research Institute
• Current challenges for data integration
• Possible solutions / limitations
• Show application of these using cheminformatic models in genetix 15:50 Afternoon refreshments
toxicology area
Sandeep Modi
Cheminformatician 16:10 A paradigm to explain development of metabolic
Unilever disorders/diseases
• A general explanation of the molecular mechanism and pathway of
diseases by any simple and universal paradigm is still a daunting task in this
11:30 Morning refreshments millennium characterised by high throughput biomolecular data production
and high performance computing fortified with efficient algorithms
11:50 Assessing the complementarities of databases • What could be the cause of these newly emerging diseases?
that integrate data between drug targets and • Propose a simple theory of cause of metabolic diseases. In this paradigm
bioactive compounds it will be possible to predict new diseases and also explain the inter-
• Content overlap provides useful insights relationships between apparently distinct diseases
• The expansion of data-integrated bioactive space relevant to drug Dr. Meeta Rani Mannaert
discovery and chemical biology Chief Research Officer, HPC Project,
• Both commercial and public sources are complementary for its exploration University of Pecs
Christopher Southan
Contractor, AstraZeneca
16:50 Biodiveristy informatics component-strategic
Special Professor of Proteomics,
objectives and perspectives
University of Nottingham, Biosciences
• Analysing trends in biodiversity information management
• Assessment of completeness of biodiversity data
12:30 Applications of Genome Scale Metabolic Network • Advancements made so far
modelling for Drug Discovery
• Building in-silico metabolic models: genome scale metabolic network
reconstruction 17:30 Closing remarks from the chair
• Systems biology approaches for metabolic network modelling
• Applications of genome scale metabolic networks to drug discovery 17:40 Networking drinks
Dr. Bhushan Bonde Take your discussions further and build new
Principal Scientist (Bioinformatics) relationships in a relaxed and informal setting
GlaxoSmithKline
Due to unforeseen circumstances the programme may change and visiongain reserves the right to alter the venue and/or speakers c Copyright visiongain Ltd, 2010

4. Day 2
Bioinformatics Conference 2010
Tuesday 18th May 2010, London, UK
09:30 Registration and refreshments 13:10 Networking lunch
10:00 Opening address from the chair
14:30 Data integration and bioinformatics – problems
and solutions
10:10 Healthcare informatics challenges for an aging society
• Pharmaceutical company moving towards global healthcare corporation • Contemporary biological research relies on access to data from many
different resources
• Healthcare paradigm shift from traditional inpatient care towards
home-based care
• The automatic integration of biological data is challenging because of the
• Develop solutions that span from wellness to illness care scale and heterogeneity of the available data
• Role of informatics to enable a consumer healthcare business model
• Provide an overview of a general-purpose data integration platform (Ondex)
• Vision-Gain from a true integrated and diversified healthcare system that has been developed by Rothamsted Research and collaborators
Dr. Adel Laoui
Director, Healthcare Technologies Aging Therapeutic Strategic Unit • Ondex combines data integration, data visualisation and analysis methods
Sanofi Aventis that facilitate working with large scale biological networks (e.g. of genes,
proteins, biochemical pathways etc)
10:50 Bioinformatics for public health microbiology
• Illustrations will be provided of the how Ondex has been used to
• The ‘research to surveillance’ informatics continuum overcome data integration problems and how integrated analysis of
• Communicating and translating data into ‘information for action’ biological networks has revealed novel biological discoveries
• Data integration needs and challenges for infectious disease management Prof. Chris Rawlings
and control Scientific Director of Centre for Mathematical and Computational
Biology and Head of Department of Biomathematics and Bioinformatics
• Looking forward – the impact of new technologies Rothamsted Research
Dr. Jon Green
Head of Bioinformatics Unit
Health Protection Agency 15:10 Processing and archiving experiment data with the
AnIML data standard
11:30 Morning refreshments
• A look at the current state of laboratory and bioinformatics
11:50 A unifying theory for GC3 biology in plants and animals • Introduction to the AnIML standard for analytical data
• Two kinds of genes in plants and animals • Using generic software components to streamline working with analytical data
• Most probable explanations for GC3 bimodality
• Making it easier to exchange data from different instruments
• Role of biased gene conversion
• Transcriptional advantage of high GC3 • Long-term archiving of laboratory data
• Effects of gene methylation in biological systems Burkhard Schaefer
President
• Applications of GC3 for functional genome annotation
BSSN Software
Dr Tatiana Tatarinova
Senior Lecturer in Statistics
University of Glamorgan
15:50 Afternoon refreshments
12:30 Bioinformatics, integration, virtualisation and “Elastic
Computing”. A new way to run your analysis pipelines?
16:10 Analysing the future regulatory environment
• Data management and analysis is becoming more expensive
• Assessing the legal aspects
• Data volumes continue to increase with new technology and will continue
to do so • Examining the current issues in bioinformatics patenting
• Hardware and support are largely “Hidden” costs • Evaluation plans for license acquisition
• Pharma and biotech and constantly looking for ways to streamline their
organisations and save money
16:50 Chair’s closing remarks
• Flexibility Vs IT process
• Can outsourcing and virtualisation help?
Rob Gill 17:00 End of Conference
Director
AnurOS

5. Registration Form
Bioinformatics Conference 2010
17th – 18th May 2010, London, UK
Angel
For multiple bookings Pentonville Road
Photocopy this form Conf. code VG
Bioinformatics
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Conference only Fee: £1299 VAT: £227.33 Total: £1526.33
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