5. Typical vs. Atypical Chest Pain
Typical
Characterized as
discomfort/pressure rather than
pain
Time duration >2 mins
Provoked by activity/exercise
Radiation (i.e. arms, jaw)
Does not change with
respiration/position
Associated with
diaphoresis/nausea
Relieved by rest/nitroglycerin
Atypical
Pain that can be localized with
one finger
Constant pain lasting for days
Fleeting pains lasting for a few
seconds
Pain reproduced by
movement/palpation
8. Case 1
You are the orphan intern on Wearn team at 6PM. You
are called by the nurse because Ms. Z has developed
chest pain. Ms. Z is a 62 yo F with PMHx of CAD s/p
remote PCI to the LAD, COPD and right THA 3 weeks
ago who was admitted for a COPD exacerbation.
What would you do next?
9. Evaluation of Chest Pain
Case 1:
Ask nurse for most current set of vital signs
Ask nurse to get an EKG
Obtain the admission EKG from the paper chart
Go see the patient!
10. Evaluation of Chest Pain
Once at bedside, determine if patient is stable or unstable
Perform focused history and physical exam
Read and interpret the EKG. Compare EKG to old EKG if
available
If patient looks unstable or has concerning EKG findings, call
your senior resident for help
Write a clinical event note!
11. Evaluation of Chest Pain
focused physical exam for chest pain
Vital Signs: tachycardia, hypertension/hypotension or hypoxia
General: Sick appearing, actively having chest pain
HEENT: JVD, carotid bruits
Chest: Rales, wheezes or decreased breath sounds
CVS: New murmurs, reproducible chest pain, s3 gallop
Abd: Abdominal tenderness, pulsatile mass
Ext: Edema, peripheral pulses
Skin: Rash on chest wall
12. Case 1
You go see the patient. She had been feeling better after getting
duonebs, but suddenly developed chest pain that is L-sided, 8/10
and worse with breathing. This pain is not like her prior MI.
Vital signs: Afebrile, HR 120, BP 110/70, RR 28, O2 sat 89% on 2L
(was 95% on RA this morning)
Physical exam
Gen – in distress, using accessory muscles of respiration
Lungs – CTAB, no rales/wheezes
Heart – tachycardic, nl s1, loud s2, no mumurs
Abd – soft, NT/ND, active BS
Ext – b/l LEs warm and well perfused
Labs:
CBC wnl, RFP wnl, BNP = 520, D-dimer = positive, Troponin = 0.12
16. Modified Wells Criteria
Clinical symptoms of DVT (3 points)
Other diagnoses less likely than PE (1 point)
Heart Rate >100 (1.5 points)
Immobilization >/= 3 days or surgery within 4 weeks (1.5 points)
Previous DVT/PE (1.5 points)
Hemoptysis (1 point)
Malignancy (1 point)
Interpretation:
>6: high
2-6: moderate
<2: low
17. Next moves
DDIMER: 95% sensitive, VERY nonspecific
ABG – Elevated A-a gradient fairly sensitive, highly
nonspecific
EKG – most commonly nonspecific changes (ST/T wave
changes, etc)
V/Q scan – helpful in patients with HIGH or LOW pretest
probabilities in whom a CTPE cannot be obtained (eg CKD)
LE Ultrasound: not sensitive
CTPE
Sensitivity 83%
Specificity 96%
Moderate - high clinical probability and positive CTPE: 92-96%
chance of PE
18. Pearl
A CT angiogram (important for evaluating for Pulmonary
Embolism or Aortic Dissection) requires EITHER:
1) At least a 20G peripheral IV
OR
2) A Power injectable central line
In keeping with this being intern bootcamp, I’m going to focus on common scenarios you’ll encounter in hospitalized patients
I’ll try to keep this relevant, with some lessions I’ve learned along the way
MI
PE
Dissection (20G IV!)
Costocondiritis/musculoskeletal
Esophageal Spasm
Acute Chest
PNA
pericarditis
Pleuritis
Heartburn
RUQ pathology
Panic attack
Cocaine chest pain
Aortic Stenosis
Myocarditis
Eosinophilic Esophagitis
Esophageal Rupture/Perforation
Asthma/COPD
Pneumothorax
Pearls:
don’t accept “chest pain” – could be abdominal, patients haven’t read the anatomy books! (story of kidney stones)
Need 20G IV or power injectable central line for contrast – important for PE and TAA
MI: continued chest pain on floor in NSTEMI
TPA in PE
(just because the ER says it is chest pain doesn’t mean it’s not abdominal pain)
If the patient can localize pain with 1 finger, less likely to be ACS
Many patients will indicate abdomen but say “chest.”
Question: would would rash on chest wall indicate?
ABG – A-a gradient can be normal in ~6% of patients with PE,
EKG – 70% had changes, in one study
LE ultrasound: only 29% of patients with known PE had + u/s in one study. False positive ~3%.
Can help to define clot burden in cases of known PE
Echo: only 30-40% sensitive
Echocardiolography – useful for suspected massive/submassive PE where use of thrombolytics is in question.
V/Q Scan:
Useful in the following scenarios:
Renal insufficiency
Contrast allergy
Morbid obesity
Inconclusive CTPE
- Helpful scenarios:
High clinical probability with high likelihood V/Q: 95% chance of PE
Low clinical probability with low probability V/Q: 4% chance of PE
Normal V/Q essentially excludes PE
Other situations, V/Q scan is insufficient to diagnose or exclude PE