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Approach to Chest Pain
Intern Bootcamp, 2014
Nathan Stehouwer, MD
PGY-4, Internal Medicine & Pediatrics
Differential
Pearl: ALWAYS have the patient
point to the pain!
Typical vs. Atypical Chest Pain
Typical
 Characterized as
discomfort/pressure rather than
pain
 Time duration >2 mins
 Provoked by activity/exercise
 Radiation (i.e. arms, jaw)
 Does not change with
respiration/position
 Associated with
diaphoresis/nausea
 Relieved by rest/nitroglycerin
Atypical
 Pain that can be localized with
one finger
 Constant pain lasting for days
 Fleeting pains lasting for a few
seconds
 Pain reproduced by
movement/palpation
Typical vs. Atypical Chest Pain
UpToDate
Typical vs. Atypical Chest Pain
Cayley 2005
Case 1
 You are the orphan intern on Wearn team at 6PM. You
are called by the nurse because Ms. Z has developed
chest pain. Ms. Z is a 62 yo F with PMHx of CAD s/p
remote PCI to the LAD, COPD and right THA 3 weeks
ago who was admitted for a COPD exacerbation.
 What would you do next?
Evaluation of Chest Pain
Case 1:
 Ask nurse for most current set of vital signs
 Ask nurse to get an EKG
 Obtain the admission EKG from the paper chart
 Go see the patient!
Evaluation of Chest Pain
 Once at bedside, determine if patient is stable or unstable
 Perform focused history and physical exam
 Read and interpret the EKG. Compare EKG to old EKG if
available
 If patient looks unstable or has concerning EKG findings, call
your senior resident for help
 Write a clinical event note!
Evaluation of Chest Pain
focused physical exam for chest pain
 Vital Signs: tachycardia, hypertension/hypotension or hypoxia
 General: Sick appearing, actively having chest pain
 HEENT: JVD, carotid bruits
 Chest: Rales, wheezes or decreased breath sounds
 CVS: New murmurs, reproducible chest pain, s3 gallop
 Abd: Abdominal tenderness, pulsatile mass
 Ext: Edema, peripheral pulses
 Skin: Rash on chest wall
Case 1
 You go see the patient. She had been feeling better after getting
duonebs, but suddenly developed chest pain that is L-sided, 8/10
and worse with breathing. This pain is not like her prior MI.
 Vital signs: Afebrile, HR 120, BP 110/70, RR 28, O2 sat 89% on 2L
(was 95% on RA this morning)
 Physical exam
 Gen – in distress, using accessory muscles of respiration
 Lungs – CTAB, no rales/wheezes
 Heart – tachycardic, nl s1, loud s2, no mumurs
 Abd – soft, NT/ND, active BS
 Ext – b/l LEs warm and well perfused
 Labs:
 CBC wnl, RFP wnl, BNP = 520, D-dimer = positive, Troponin = 0.12
Case 1
Case 1
Differential
Modified Wells Criteria
 Clinical symptoms of DVT (3 points)
 Other diagnoses less likely than PE (1 point)
 Heart Rate >100 (1.5 points)
 Immobilization >/= 3 days or surgery within 4 weeks (1.5 points)
 Previous DVT/PE (1.5 points)
 Hemoptysis (1 point)
 Malignancy (1 point)
 Interpretation:
 >6: high
 2-6: moderate
 <2: low
Next moves
 DDIMER: 95% sensitive, VERY nonspecific
 ABG – Elevated A-a gradient fairly sensitive, highly
nonspecific
 EKG – most commonly nonspecific changes (ST/T wave
changes, etc)
 V/Q scan – helpful in patients with HIGH or LOW pretest
probabilities in whom a CTPE cannot be obtained (eg CKD)
 LE Ultrasound: not sensitive
 CTPE
 Sensitivity 83%
 Specificity 96%
 Moderate - high clinical probability and positive CTPE: 92-96%
chance of PE
Pearl
A CT angiogram (important for evaluating for Pulmonary
Embolism or Aortic Dissection) requires EITHER:
1) At least a 20G peripheral IV
OR
2) A Power injectable central line
Case 1
Continue reading…
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Approach to Chest Pain

  • 1. Approach to Chest Pain Intern Bootcamp, 2014 Nathan Stehouwer, MD PGY-4, Internal Medicine & Pediatrics
  • 3.
  • 4. Pearl: ALWAYS have the patient point to the pain!
  • 5. Typical vs. Atypical Chest Pain Typical  Characterized as discomfort/pressure rather than pain  Time duration >2 mins  Provoked by activity/exercise  Radiation (i.e. arms, jaw)  Does not change with respiration/position  Associated with diaphoresis/nausea  Relieved by rest/nitroglycerin Atypical  Pain that can be localized with one finger  Constant pain lasting for days  Fleeting pains lasting for a few seconds  Pain reproduced by movement/palpation
  • 6. Typical vs. Atypical Chest Pain UpToDate
  • 7. Typical vs. Atypical Chest Pain Cayley 2005
  • 8. Case 1  You are the orphan intern on Wearn team at 6PM. You are called by the nurse because Ms. Z has developed chest pain. Ms. Z is a 62 yo F with PMHx of CAD s/p remote PCI to the LAD, COPD and right THA 3 weeks ago who was admitted for a COPD exacerbation.  What would you do next?
  • 9. Evaluation of Chest Pain Case 1:  Ask nurse for most current set of vital signs  Ask nurse to get an EKG  Obtain the admission EKG from the paper chart  Go see the patient!
  • 10. Evaluation of Chest Pain  Once at bedside, determine if patient is stable or unstable  Perform focused history and physical exam  Read and interpret the EKG. Compare EKG to old EKG if available  If patient looks unstable or has concerning EKG findings, call your senior resident for help  Write a clinical event note!
  • 11. Evaluation of Chest Pain focused physical exam for chest pain  Vital Signs: tachycardia, hypertension/hypotension or hypoxia  General: Sick appearing, actively having chest pain  HEENT: JVD, carotid bruits  Chest: Rales, wheezes or decreased breath sounds  CVS: New murmurs, reproducible chest pain, s3 gallop  Abd: Abdominal tenderness, pulsatile mass  Ext: Edema, peripheral pulses  Skin: Rash on chest wall
  • 12. Case 1  You go see the patient. She had been feeling better after getting duonebs, but suddenly developed chest pain that is L-sided, 8/10 and worse with breathing. This pain is not like her prior MI.  Vital signs: Afebrile, HR 120, BP 110/70, RR 28, O2 sat 89% on 2L (was 95% on RA this morning)  Physical exam  Gen – in distress, using accessory muscles of respiration  Lungs – CTAB, no rales/wheezes  Heart – tachycardic, nl s1, loud s2, no mumurs  Abd – soft, NT/ND, active BS  Ext – b/l LEs warm and well perfused  Labs:  CBC wnl, RFP wnl, BNP = 520, D-dimer = positive, Troponin = 0.12
  • 16. Modified Wells Criteria  Clinical symptoms of DVT (3 points)  Other diagnoses less likely than PE (1 point)  Heart Rate >100 (1.5 points)  Immobilization >/= 3 days or surgery within 4 weeks (1.5 points)  Previous DVT/PE (1.5 points)  Hemoptysis (1 point)  Malignancy (1 point)  Interpretation:  >6: high  2-6: moderate  <2: low
  • 17. Next moves  DDIMER: 95% sensitive, VERY nonspecific  ABG – Elevated A-a gradient fairly sensitive, highly nonspecific  EKG – most commonly nonspecific changes (ST/T wave changes, etc)  V/Q scan – helpful in patients with HIGH or LOW pretest probabilities in whom a CTPE cannot be obtained (eg CKD)  LE Ultrasound: not sensitive  CTPE  Sensitivity 83%  Specificity 96%  Moderate - high clinical probability and positive CTPE: 92-96% chance of PE
  • 18. Pearl A CT angiogram (important for evaluating for Pulmonary Embolism or Aortic Dissection) requires EITHER: 1) At least a 20G peripheral IV OR 2) A Power injectable central line

Editor's Notes

  1. In keeping with this being intern bootcamp, I’m going to focus on common scenarios you’ll encounter in hospitalized patients I’ll try to keep this relevant, with some lessions I’ve learned along the way MI PE Dissection (20G IV!) Costocondiritis/musculoskeletal Esophageal Spasm Acute Chest PNA pericarditis Pleuritis Heartburn RUQ pathology Panic attack Cocaine chest pain Aortic Stenosis Myocarditis Eosinophilic Esophagitis Esophageal Rupture/Perforation Asthma/COPD Pneumothorax Pearls: don’t accept “chest pain” – could be abdominal, patients haven’t read the anatomy books! (story of kidney stones) Need 20G IV or power injectable central line for contrast – important for PE and TAA MI: continued chest pain on floor in NSTEMI TPA in PE
  2. (just because the ER says it is chest pain doesn’t mean it’s not abdominal pain) If the patient can localize pain with 1 finger, less likely to be ACS Many patients will indicate abdomen but say “chest.”
  3. Question: would would rash on chest wall indicate?
  4. ABG – A-a gradient can be normal in ~6% of patients with PE, EKG – 70% had changes, in one study LE ultrasound: only 29% of patients with known PE had + u/s in one study. False positive ~3%. Can help to define clot burden in cases of known PE Echo: only 30-40% sensitive Echocardiolography – useful for suspected massive/submassive PE where use of thrombolytics is in question. V/Q Scan: Useful in the following scenarios: Renal insufficiency Contrast allergy Morbid obesity Inconclusive CTPE - Helpful scenarios: High clinical probability with high likelihood V/Q: 95% chance of PE Low clinical probability with low probability V/Q: 4% chance of PE Normal V/Q essentially excludes PE Other situations, V/Q scan is insufficient to diagnose or exclude PE