ANTIBIOTICS

1. FINC NURSING CHOACHING
AGRA
ANTIBIOTICS

2. INTRODUCTION-
• AN ANTIBIOTIC IS AN IMPRECISELY
APPLIED TERM , GENERALLY USED TO
DESCRIBE ANY COMPOUND (NATURAL
OR SYNTHETIC) THAT INHIBITS THE
GROWTH OF , OR ACTIVELY KILLS ,
MICROORGANISMS.

3. BACTERIOSTATIC-
• INHIBITS BACTERIA FROM REPRODUCING
BUT DOESN’T OTHERWISE KILL THEM
BACTERIOCIDAL –
• ACTIVELY KILLS BACTERIA

4. TRICKS USED FOR LEARN ANTIBIOTICS
NAME-
• TRICKS-
• TIPU SULTAN KA BETA NIZAM NIKLA
NIKKAMA AALSI BOLA APNI DRAMA QUEEN
KE SATH MACRONI PAKA KE LG TV PE
POKYMON $NINZA DEKHUGA OK

5. CONT…
• TIPU- TETRACYCLIN
• SULTAN – SULPHONEMIDE
• BETA- BETA LACTUM
• NIZAM – NITROMIDAZOLE
• NIKKAMA- NICOTIN ACID DERIVATIVES
• AALSI –AZOLE DERIVATIVES
• APNI- AMINOGLYCOSIDES
• DRAMA- DIAAMINOPYRIMIDINE DERIVATIVE
• QUEEN- QUINOLONE

6. CONT…
• MACRONI – MACROLIDE
• PAKA – POLYENE
• L- LINCOSEMIDE
• G- GLYCOPEPTIDE
• POKYMON –POLYPEPTIDE
• NINZA – NITROBENZENE DERIVATIVE
• OK - OXAZALIDINONE

7. CLASSIFICATION OF ANTIBIOTIC-
A- BASED ON CHEMICAL STRUCTURE –
• 1- QUINOLONES – E g- CIPROFLOXACIN
• 2-SULFONAMIDE AND RELATED DRUGS – E g-
DEPSONE
• 3- NITROBENZENE DERIVATIVE- E g-
CHLORRAMPHENICOL
• 4- MACROLIDE ANTIBIOTIC – E g -
ERYTHROMYCIN

8. CONT…
• 5-NICOTINIC ACID DERIVATIVES- E g
ISONIAZID
• 6- NITROMIDAZOL- E g METRONIDAZOLE
• 7- POLYENE ANTIBIOTICS – E g -
AMPHOTERICIN
• 8- AMINOGLYCOSIDES – E g – STREPTOMYCIN

9. B- BASED ON MECHANISM -
• 1- INHIBIT CELL WALL CYNTHESIS –
PENICILLIN
• 2- CAUSE LEAKAGE FROM CELL MEMBREANE
– POLYPETIDES , POLYENE
• 3- INHIBIT PROTEIN SYNTHESIS –
TETRACYCLINES , LENEZOID
• 4- CAUSE MISREADING OF M- RNACODE-
STREPTOMYCIN

10. CONT…
• 5- INHIBIT DNA –CIPROFLOXIN
• 6- INTERFERE WITH DNA FUNCTION-
RIFAMPIN
• 7- INTERFERE WITH DNA SYNTHESIS –
ACYCLOVIR , ZIDOVUDINE
• 8- INTERFERE WITH INTERMEDIARY
METABOLISM -METRONIDAZOLE

11. C- INHIBIT CELL WALL SYNTHESIS -
• TRICKS – (CELL VALL BURN BY PENICILLIN)
• PENICILLINS
• CEPHALOSPORINS , CYSLOSERINE ,
VANCOMYCIN
• BACITRACIN

12. D- INHIBIT PROTEIN SYNTHESIS-
• TRICKS-(CIVIL LINE EXTENDED TO PRIME
LOCATION)
• TETRACYCLINES
• CHLORAMPHENICOL
• ERYTHROMYCIN ,CLINDAMYCIN
• LINEZOLID

13. E-BASED ON SPECTRUM OF ACTIVITY-
• 1- NARROW SPECTRUM – PENICILLIN
• 2- BROAD SPECTRUM - TETRACYCLINES

14. F- BASED ON SOURCE OF ANTIBIOTIC-
• ANTIBIOTIC ARE OBTAINED –
• 1- FUNGI – PENICILLIN
• 2- BACTERIA – BACITACIN , COLISTIN
• 3- ACTINOMYCETES – TETRACYCLINES,
MACROLIDE, AMINOGLYCOSIDES

15. G- BASED ON TYPE OF ORGANISM
THEY KILL/ STOP GROWTH-
• TYPE OF ORGANISM AGAINST WHICH
PRIMARILY ACTIVE –
• 1- ANTIBACTERIAL – PENICILLIN ,
AMINOGLYCOSIDES, ERYTHROMYCIN
• 2- ANTIFUNGAL - AMPHOTERICIN –B
• 3- ANTIVIRAL – ACYCLOVIR , ZIDUVUDINE
• 4- ANTIPROTOZOAL –CHLOROQUINE ,
METRONIDAZOLE
• 5- ANTHELMINTIC -MEBENDAZOLE

16. H-BASED ON THERAPEUTIC INDEX-
1- HIGH THERAPEUTIC INDEX-
• PENICILLIN
• CEPHALOOSPORINS
• MACROLIDE
TRICKS( PCM)

17. CONT…
2- LOW THERAPEUTIC INDEX –
• CHLORAMPHENICOL
• AMINOGLYCOSIDES
• TETRACYCLINES
TRICKS(CAT)

18. 3- VERY LOW TERAPEUTIC INDEX-
• POLYMIXIN –B
• VANCOMYCIN
• AMPHOTERICIN- B

19. COMMON USES OF ANTIBIOTICS-
- BRONCHITIS
- ACHE
- URINARY TRACT INFECTION
- OTITIS MEDIA
- SKIN OR SOFT TISSUE INFECTION
- SEXUALLY TRANSMITTED DISEASE
- FLU
- SORE THROAT

20. COMMON SIDE EFFECT OF
ANTIBIOTIC-
• VOMITING
• NAUSEA
• INDIGESTION
• ANDOMINAL PAIN
• LOSSE OF APPETITE

21. SOME INSTRUCTION FOR ANTIBIOTIC
ADMINISTRATION-
• BEFORE GIVING ANTIBIOTIC SENSITIVITY TEST
DONE