- The study evaluated the in vitro activity of azithromycin, ceftriaxone, doxycycline, and various fluoroquinolones against a mutant strain of Neisseria gonorrhoeae. It determined the minimum inhibitory concentration (MIC) and mutant prevention concentration (MPC) of each drug.
- Pharmacokinetic parameters were used to model concentrations over time and calculate the percentage of time drug levels remained above the MPC and within the mutant selection window (MSW). Time-kill assays measured bacterial killing at various time points.
- All fluoroquinolones showed bactericidal activity and maintained levels above the MPC, suggesting they could prevent mutant selection. Azithromy
This document discusses project success criteria for engineering and refurbishment projects at Eskom, a South African power utility. It conducted a survey of stakeholders to identify key success criteria. The survey found that while time, cost and quality were important, other factors like satisfying business goals, customer satisfaction, and impact on plant were rated as even more important. Different stakeholders had differing views, with clients prioritizing satisfying goals, customer satisfaction and impact, while project managers prioritized quality, time and cost. Most respondents felt that time, cost and quality were not the only important success criteria. The document concludes that multiple factors are important for measuring project success.
El Zika es una amenaza sanitaria mundial. Ya que se multiplicaron los embarazos con microcefalia que, además, es de tardía detección. En Brasil, Colombia, Jamaica y El Salvador piden a las mujeres que no se embaracen. Pero no se garantizan sus derechos sexuales y reproductivos al acceso pleno a la anticoncepción y al aborto seguro. En Argentina recomiendan a las turistas que se cuiden de picaduras. Aunque, como todavía no llegó el virus, no hay un plan en marcha. Pero distintas organizaciones reclaman que se refuerce –y no se le quite personal ni recursos– al Programa de Salud Sexual y Procreación Responsable y se garantice el reparto de todos los anticonceptivos y la interrupción voluntaria del embarazo.
The document discusses alternatives to fiat currency monopolies and argues for total de-monopolization of money. It notes that any monopoly is prone to abuse and corruption. While bitcoin provides an alternative to fiat currencies, it cannot replace the loan mechanism that is essential to modern economies. For a free and just monetary system, individuals and organizations must have the right to issue their own currencies and facilitate promissory notes and loans. Technical solutions are needed to implement issuance and exchange of digital currencies independently without centralized control.
- The study evaluated the in vitro activity of azithromycin, ceftriaxone, doxycycline, and various fluoroquinolones against a mutant strain of Neisseria gonorrhoeae. It determined the minimum inhibitory concentration (MIC) and mutant prevention concentration (MPC) of each drug.
- Pharmacokinetic parameters were used to model concentrations over time and calculate the percentage of time drug levels remained above the MPC and within the mutant selection window (MSW). Time-kill assays measured bacterial killing at various time points.
- All fluoroquinolones showed bactericidal activity and maintained levels above the MPC, suggesting they could prevent mutant selection. Azithromy
This document discusses project success criteria for engineering and refurbishment projects at Eskom, a South African power utility. It conducted a survey of stakeholders to identify key success criteria. The survey found that while time, cost and quality were important, other factors like satisfying business goals, customer satisfaction, and impact on plant were rated as even more important. Different stakeholders had differing views, with clients prioritizing satisfying goals, customer satisfaction and impact, while project managers prioritized quality, time and cost. Most respondents felt that time, cost and quality were not the only important success criteria. The document concludes that multiple factors are important for measuring project success.
El Zika es una amenaza sanitaria mundial. Ya que se multiplicaron los embarazos con microcefalia que, además, es de tardía detección. En Brasil, Colombia, Jamaica y El Salvador piden a las mujeres que no se embaracen. Pero no se garantizan sus derechos sexuales y reproductivos al acceso pleno a la anticoncepción y al aborto seguro. En Argentina recomiendan a las turistas que se cuiden de picaduras. Aunque, como todavía no llegó el virus, no hay un plan en marcha. Pero distintas organizaciones reclaman que se refuerce –y no se le quite personal ni recursos– al Programa de Salud Sexual y Procreación Responsable y se garantice el reparto de todos los anticonceptivos y la interrupción voluntaria del embarazo.
The document discusses alternatives to fiat currency monopolies and argues for total de-monopolization of money. It notes that any monopoly is prone to abuse and corruption. While bitcoin provides an alternative to fiat currencies, it cannot replace the loan mechanism that is essential to modern economies. For a free and just monetary system, individuals and organizations must have the right to issue their own currencies and facilitate promissory notes and loans. Technical solutions are needed to implement issuance and exchange of digital currencies independently without centralized control.
This document discusses the partnership between science and NASA's human space flight program over the years. It notes how NASA has contributed to scientific discoveries and technological advancements through missions and projects like Hubble Space Telescope, Mars rovers, Galileo, and Apollo. The document argues that continuing this partnership can enable the construction of increasingly larger space-based telescopes to further scientific knowledge in areas like exoplanet detection, astrophysics, Earth observation, and national security.
Konkurence atkritumu apsaimniekošanā – problēmas un izaicinājumiKonkurences padome
Lai noskaidrotu, kāda ir konkurences situācija sadzīves atkritumu apsaimniekošanas tirgū un nozares attīstības perspektīvas, Konkurences padome 2015. gadā uzsāka sadzīves atkritumu apsaimniekošanas pētījumu. Prezentācija ietver būtiskākos secinājumus.
O documento discute três projetos para a orla de Ilhéus: 1) Projeto Orla, que visa revitalizar a orla priorizando pedestres e lazer; 2) Projeto de Reurbanização do Centro, priorizando praças e ruas; 3) Projeto Viário das Orlas do DERBA, priorizando veículos e conexões rodoviárias, em detrimento dos pedestres. Há preocupação que este último projeto comprometa os outros dois, ao transformar avenidas em rodovias.
Este documento presenta los requisitos para la cuarta tarea de diseño de una asignatura de diseño industrial sobre el diseño de una silla de trabajo desplazable para un estudiante universitario de diseño gráfico con discapacidad motora. Los estudiantes deben entregar dibujos a escala de la solución técnica y fabricable en una presentación de PowerPoint y planos de AutoCAD convertidos a PDF publicados en una plataforma en línea junto con sus datos personales.
على الرغم من كل التحفظات فإن نموذج هارود - دومار لا يزال بعد مرور أكثر من خمسون عاماً عليه أكثر النماذج استخداماً، كما أنه هام للغاية عند توضيح علاقة التداخل بين الأهداف الكلية للدخل والاستثمار والادخار وتأثيرها على معدل النمو. كما تعرض النموذج نفسه للتعديل ومحاولات ضبط حساب المتغيرات.
This document discusses the partnership between science and NASA's human space flight program over the years. It notes how NASA has contributed to scientific discoveries and technological advancements through missions and projects like Hubble Space Telescope, Mars rovers, Galileo, and Apollo. The document argues that continuing this partnership can enable the construction of increasingly larger space-based telescopes to further scientific knowledge in areas like exoplanet detection, astrophysics, Earth observation, and national security.
Konkurence atkritumu apsaimniekošanā – problēmas un izaicinājumiKonkurences padome
Lai noskaidrotu, kāda ir konkurences situācija sadzīves atkritumu apsaimniekošanas tirgū un nozares attīstības perspektīvas, Konkurences padome 2015. gadā uzsāka sadzīves atkritumu apsaimniekošanas pētījumu. Prezentācija ietver būtiskākos secinājumus.
O documento discute três projetos para a orla de Ilhéus: 1) Projeto Orla, que visa revitalizar a orla priorizando pedestres e lazer; 2) Projeto de Reurbanização do Centro, priorizando praças e ruas; 3) Projeto Viário das Orlas do DERBA, priorizando veículos e conexões rodoviárias, em detrimento dos pedestres. Há preocupação que este último projeto comprometa os outros dois, ao transformar avenidas em rodovias.
Este documento presenta los requisitos para la cuarta tarea de diseño de una asignatura de diseño industrial sobre el diseño de una silla de trabajo desplazable para un estudiante universitario de diseño gráfico con discapacidad motora. Los estudiantes deben entregar dibujos a escala de la solución técnica y fabricable en una presentación de PowerPoint y planos de AutoCAD convertidos a PDF publicados en una plataforma en línea junto con sus datos personales.
على الرغم من كل التحفظات فإن نموذج هارود - دومار لا يزال بعد مرور أكثر من خمسون عاماً عليه أكثر النماذج استخداماً، كما أنه هام للغاية عند توضيح علاقة التداخل بين الأهداف الكلية للدخل والاستثمار والادخار وتأثيرها على معدل النمو. كما تعرض النموذج نفسه للتعديل ومحاولات ضبط حساب المتغيرات.