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2012 Deep Research Report on China Influenza Vaccine Industry



2012 Deep Research Report on China Influenza Vaccine Industry

Hard copy: 2200 USD
Electronic copy (PDF):2200USD
Global License: 4000USD
Pages: 144
Tables and Figures: 155
Published Date: May 9 2012
Publisher: QY Research Group
Contact: Mr. Zhang Dong 86-10-82945717 86-13811796901 sales@qyresearch.com

Summary

<2012 Deep Research Report on China Influenza Vaccine Industry > was a professional and depth
research report on China Influenza Vaccine Industry. Firstly the report describes the background
knowledge of Influenza Vaccine, including Concepts Classification Manufacturing process
technical parameters and equipments List etc; then statistics International and China 16
Manufacturers Influenza Vaccine product 2009-2016 Capacity production cost price production
value profit margins and other relevant data, statistics these enterprises Influenza Vaccine
products, Product Specifications, company background information, then summary statistics and
analysis the relevant data on these enterprises. The report got Global and China Influenza Vaccine
companies production market share, China Influenza Vaccine demand supply and shortage, China
Influenza Vaccine 2009-2016 production price cost profit production value profit margins,
production market share by different Sources(China Domestic and Imported etc) . At the same
time, the report analyzed and discussed supply and demand changes in Influenza Vaccine market
and business development strategies, conduct a comprehensive analysis on China Influenza
Vaccine industry trends. Finally, the report also introduced 8Million Pieces/year Influenza Vaccine
project Feasibility analysis and related research conclusions. In a word, It was a depth research
report on China Influenza Vaccine industry. And thanks to the support and assistance from
Influenza Vaccine industry chain related experts and enterprises during QYResearch Vaccine
Research Team survey and interview.




QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717                   1(8 Total)
2012 Deep Research Report on China Influenza Vaccine Industry



Table of Contents

Chapter One Influenza Vaccine Industry Overview     1
1.1 Definition 1
1.2 Classification 2
1.2.1 Seasonal Influenza Vaccine 2
1.2.2 Type A H1N1 Influenza Vaccine 4
1.2.3 Two Type Influenza Vaccine Comparison 6
1.3 Vaccine Inoculation 7
1.4 Industry Chain Structure 9
1.5Influenza Vaccine Development Prospect 15
1.5.1 United States Overplus 15
1.5.2 Seek Competitive Differentiation New Technology Prevalence 17
1.5.3 Huge Market Demand in China 18

Chapter Two Influenza Vaccine Manufacturing Technology and Process 19
2.1 Influenza Vaccine Manufacturing Technology Overview19
2.1.1 Embryo Culture Type A H1N1 Influenza Vaccine Manufacturing Process 20
2.1.2 Vero Cell Culture Inactivated Influenza Vaccine Manufacturing Process 23
2.2 Comparison of Two Procee Method 26
2.2.1 Embryo Culture Inactivated Influenza Vaccine Process Flow     26
2.2.2 Cell Culture Inactivated Influenza Vaccine Process Flow 27
2.2.3 Two Manufacturing Process Comparison 28
2.3 Influenza Vaccine Manufacturing Equipments List 30
2.4 Influenza Vaccine Manufacturing Process Today and Tomorrow 33
2.4.1 Influenza Vaccine Manufacturing Process Status 33
2.4.2 H1N1 Influenza Vaccine Manufacturing Process Problems 33
2.4.3 Influenza Vaccine New Manufacturing Technology 34

Chapter Three Influenza Vaccine Production Supply Sales Demand Market Status and Forecast
     38
3.1 Influenza Vaccine Productions Overview 38
3.2 Influenza Vaccine Demand Overview 49
3.4 Influenza Vaccine Cost Price Production Value Gross Margin53

Chapter Four Influenza Vaccine Key Manufacturers         57
4.1 Hualan Bio (Henan) 57
4.2 Sinovac (Beijing) 65
4.3 Tianyuan Bio-pharma (Zhejiang) 73
4.4 Changsheng (Jilin Changchun) 77
4.5 Aleph Biomedical (Liaoning) 81
4.6 SIOBP (Shanghai) 87
4.7 CCBIO (Jilin Changchun)      91

QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717             2(8 Total)
2012 Deep Research Report on China Influenza Vaccine Industry

4.8 Lanzhou Institute of Biological Products (Qinghai)95
4.9 Tiantan Biological (Beijing) 99
4.10 Sanofi-pasteur (France) 105
4.11 GSK (UK)       109
4.12 Novartis (Switzerland) 116
4.13 Abbott (US) 122
4.14 Crucell (Holland) 125
4.15 Tasly&Jenner (Tianjin) 130
4.16 Neptunus Interlong (Shenzhen) 134

Chapter Five China 8Million Pieces/Year Influenza Vaccine Project Investment Feasibility
Analysis 139
5.1 China 8Million Pieces/Year Influenza Vaccine Project Opportunities and Risks Analysis 139
5.1.1 Opportunities 139
5.1.2 Risks    140
5.3 China 8Million Pieces/Year Influenza Vaccine Project Investment Feasibility Analysis140
5.3.1 Project Overview 141
5.3.2 Capacity 141
5.3.3 Construction Standards 141
5.3.3 Construction Period     141
5.3.4 Project Schedule 141
5.3.5 Investment Feasibility Analysis 142

Chapter Six Influenza Vaccine Industry Research Conclusions          143



Tables and Figures

Table Common Vaccines Classification 2
Table Three Type Influenza Vaccine (Inactivated Whole Virus Vaccine Split Vaccine Subunit
Vaccine) Characteristic Comparison    4
Table United States Approval Type A influenza H1N1 Vaccine Suppliers and Product
Specifications List 5
Table Europe Approval Type A influenza H1N1 Vaccine Suppliers and Product Specifications List
     6
Figure China First Type Vaccine and Second Type Vaccine Classification and Application 10
Table First Type Vaccine and Second Type Vaccine Detail Market Analysis10
Table 2009-2010 China First Type Vaccine and Second Type Vaccine Issue Number (10K Pieces)
and Market Share 11
Figure 2010 State-owned Private Foreign Enterprise Market Share in First Type Vaccine and
Second Type Vaccine 11
Figure Influenza Vaccine Industry Chain Structure   12
Figure Vaccine Cold Chain Circulation System 13
Figure Vaccine Transportation Model 13

QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717              3(8 Total)
2012 Deep Research Report on China Influenza Vaccine Industry

Figure First Type Vaccine Transportation Channel14
Figure Second Type Vaccine Transportation Channel 14
Figure Vaccine Transportation Steps and Process 15
Figure 2009-2019 Global Influenza Vaccine Market Scale(100 Million USD) 16
Figure 2007-2008 United States TOP5 Suppliers Influenza Vaccine Market Share 17
Figure China Influenza Vaccine Inoculation Coverage Rate and Its Gap to International Goal 18
Table Baxter Vero Cell Platform Background Information 23
Figure Embryo Culture Inactivated Vaccine Manufacturing Process Flow 26
Figure Cell Culture Inactivated Influenza Vaccine Manufacturing Process Flow 27
Figure Two Influenza Vaccine Manufacturing Process Comparison 28
Figure Influenza Vaccine Manufacturing Steps 30
Figure Influenza Vaccine Detection Steps 31
Table Influenza Vaccine Manufacturing Equipments List (38 Equipments) 32
Figure Influenza Vaccine Production Periodic Table 33
Figure Influenza Vaccine Production schedules 34
Table Influenza Vaccine Development History 35
Table Existing and R&D Influenza Vaccine Products List 35
Figure Influenza Vaccine New Manufacturing Technology 37
Table China 11 Manufacturers Influenza Vaccine Market Status List 38
Table Selling Influenza Vaccine in China 5 Foreign Suppliers List   39
Table 2009-2016 China 11 Manufacturers Influenza Vaccine Capacity and Total Capacity (10K
Pieces) List 40
Table 2009-2016 China 11 Manufacturers Influenza Vaccine Capacity Market Share List 40
Table 2009-2016 China 11 Manufacturers Influenza Vaccine Production and Total Production
(10K Pieces) List 41
Table 2009-2016 China 11 Manufacturers Influenza Vaccine Production Market Share List      42
Table 2009-2016 China Influenza Vaccine Capacity Production (10K Pieces) and Capacity
Utilization Rate    42
Figure 2009-2016 China Influenza Vaccine Capacity Production (10K Pieces) and Growth Rate
     43
Figure 2011 China Key Manufacturers Influenza Vaccine Production Market Share (China
Government Approcal Data) 43
Table 2009-2016 Global Key Suppliers Influenza Vaccine Capacity and Total Capacity (100
Million Pieces) List43
Table 2009-2016 Global Key Suppliers Influenza Vaccine Production and Total Production (100
Million Pieces) List44
Figure 2009-2016 Global Influenza Vaccine Capacity Production (100 Million Pieces) and Growth
Rate 44
Table 2009-2016 Global Influenza Vaccine Capacity Production (100 Million Pieces) and
Capacity Utilization Rate     45
Figure 2011 Global Key Suppliers Influenza Vaccine Production Market Share 45
Table 2009-2016 Global Key Suppliers Influenza Vaccine China Sales (10K Pieces) List 45
Figure 2011 China Imported Influenza Vaccine Market Share By Suppliers (China Government
Approval Data)      46

QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717              4(8 Total)
2012 Deep Research Report on China Influenza Vaccine Industry

Table Global and China Key Suppliers Key Vaccine Products Sales in China 46
Table 2007-2011 China Influenza Vaccine Approval Amount by Suppliers (10K Pieces) 47
Figure 2011 China Influenza Vaccine Market Share by Splitting Vaccine and Subunit Vaccine
(according China government approval amount) 48
Table 2009-2016 China local Influenza Vaccine and Imported Influenza Vaccine Market Share
Comparison 48
Table 2001-2020 China Birth Rate and Population (10K) 49
Figure China India Korea Japan etc 9 Countries Child Mortality (‰) 49
Figure 1950-2050 China Working-age Population Proportion (%)       50
Table 2000-2050 China Age Over 60 Population (100 Million) and Proportion (%) 50
Figure 2010-2050 China Age Over 60 Over 65 Over 80 Population Proportion 51
Table 2001-2015 China Per Capita GDP (USD) and Growth Rate         51
Figure 2009-2016 China Influenza Vaccine Supply Demand (10K Pieces) and Growth Rate 52
Figure China Japan France etc 9 Countries Age Over 65 Population Influenza Vaccine Inoculation
Coverage Rate52
Table 2009-2016 China Influenza Vaccine Supply Demand and Shortage (10K Pieces) 53
Table 2011 Hangzhou Disease Control and Prevention Center 33 Type Influenza Vaccine Products
Purchase and Selling Price (RMB/Piece)      53
Table 2011 China and Imported Influenza Vaccine Capacity Production (10K Pieces) Price Cost
Profit (RMB/Piece) Gross Margin List 56
Table 2009-2016 China Influenza Vaccine Capacity Production (10K Pieces) Price Cost Gross
(RMB/Piece) Production Value (10K RMB) Gross Margin List 56
Table Hualan Bio Company Information Table(Products Development History Location
Background Contact Information etc 14 Items) 57
Figure Hualan Bio Vaccine Factory Picture 58
Figure Hualan Bio Influenza Virus Split Vaccine (Childhood Type) 59
Figure Hualan Bio Influenza Virus Split Vaccine (Adult Type) 61
Figure Hualan Bio Type A H1N1 Influenza Virus Split Vaccine 62
Table 2009-2016 Hualan Bio Influenza Virus Split Vaccine Capacity Production (10K Pieces)
Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List        64
Figure 2009-2016 Hualan Bio Influenza Virus Split Vaccine Capacity Production (10K Pieces)
and Growth Rate 64
Table Sinovac Biotech Company Information Table(Products Development History Location
Background Contact Information etc 14 Items) 65
Table Sinovac Biotech Vaccine Plant Picture 66
Table Sinovac Biotech Development History Time Table 66
Figure Sinovac Biotech Influenza Virus Split Vaccine-Anrlaifu 67
Figure Sinovac Biotech Pandemic Influenza Virus Inactivated Vaccine - Panrlaifu 69
Figure Sinovac Biotech Type A H1N1 Influenza Virus Split Vaccine - Panrlaifu.1   71
Table 2009-2016 Sinovac Biotech Influenza Virus Split Vaccine Capacity Production (10K Pieces)
Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List        72
Figure 2009-2016 Sinovac Biotech Influenza Virus Split Vaccine Capacity Production (10K
Pieces) and Growth Rate73
Table Tianyuan Bio-pharma Company Information Table(Products Development History Location

QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717              5(8 Total)
2012 Deep Research Report on China Influenza Vaccine Industry

Background Contact Information etc 14 Items) 73
Figure Tianyuan Bio-pharma Influenza Vaccine Products List 75
Figure Tianyuan Bio-pharma Influenza Virus Split Vaccine - Yuganning 75
Table 2009-2016 Tianyuan Bio-pharma Influenza Virus Split Vaccine Capacity Production (10K
Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 76
Figure 2009-2016 Tianyuan Bio-pharma Influenza Virus Split Vaccine Capacity Production (10K
Pieces) and Growth Rate77
Table Changsheng Company Information Table(Products Development History Location
Background Contact Information etc 14 Items) 77
Figure Changsheng Influenza Virus Split Vaccine - Wanxin 79
Figure Changsheng Type A H1N1 Influenza Virus Split Vaccine 80
Table 2009-2016 Changsheng Influenza Virus Split Vaccine Capacity Production (10K Pieces)
Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List      80
Figure 2009-2016 Changsheng Influenza Virus Split Vaccine Capacity Production (10K Pieces)
and Growth Rate 81
Table Aleph Biomedical Company Information Table(Products Development History Location
Background Contact Information etc 14 Items) 81
Table Aleph Biomedical Contact Information List82
Figure Aleph Biomedical Influenza Vaccine Manufacturing Workshop       83
Figure Aleph Biomedical Influenza Virus Split Vaccine(Adult Type) 84
Figure Aleph Biomedical Influenza Virus Split Vaccine (Childhood Type) 85
Table 2009-2016 Aleph Biomedical Influenza Virus Split Vaccine Capacity Production (10K
Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 86
Figure 2009-2016 Aleph Biomedical Influenza Virus Split Vaccine Capacity Production (10K
Pieces) and Growth Rate86
Table SIOBP (Shanghai Institute of Biological Products) Company Information Table(Products
Development History Location Background Contact Information etc 14 Items) 87
Figure CNBG and Six Institutes Equity Relationship 88
Figure SIOBP Influenza Virus Split Vaccine 89
Figure SIOBP Type A H1N1 Influenza Virus Split Vaccine 89
Table 2009-2016 SIOBP Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price
Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 90
Figure 2009-2016 SIOBP Influenza Virus Split Vaccine Capacity Production (10K Pieces) and
Growth Rate 91
Table CCBIO(Changchun Institute of Biological Products) Company Information Table(Products
Development History Location Background Contact Information etc 14 Items) 91
Figure CCBIO Influenza Split Vaccine - Shipulir 93
Figure CCBIO Factory Workshop Picture 93
Table 2009-2016 CCBIO Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price
Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 94
Figure 2009-2016 CCBIO Influenza Virus Split Vaccine Capacity Production (10K Pieces) and
Growth Rate 95
Table Lanzhou Institute of Biological Products Company Information Table(Products
Development History Location Background Contact Information etc 14 Items) 95

QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717            6(8 Total)
2012 Deep Research Report on China Influenza Vaccine Industry

Figure Lanzhou Institute of Biological Products Factory Picture 97
Figure Lanzhou Institute of Biological Products Trivalent Influenza Split Vaccine 97
Table 2009-2016 Lanzhou Institute of Biological Products Influenza Virus Split Vaccine Capacity
Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross
Margin List 97
Figure 2009-2016 Lanzhou Institute of Biological Products Influenza Virus Split Vaccine Capacity
Production (10K Pieces) and Growth Rate 98
Table Tiantan Biological Company Information Table(Products Development History Location
Background Contact Information etc 14 Items) 99
Figure Tiantan Biological Control Shares of Sinopharm       101
Figure Tiantan Biological and Related Control Subsidiaries Relationship 101
Figure Tiantan Biological Factory Picture 102
Figure Tiantan Biological Beijing Yizhuang Vaccine Plants Picture 102
Figure Tiantan Biological Type A H1N1 Influenza Virus Split Vaccine        103
Figure Tiantan Biological Influenza Virus Split Vaccine     103
Table 2009-2016 Tiantan Biological Influenza Virus Split Vaccine Capacity Production (10K
Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 104
Figure 2009-2016 Tiantan Biological Influenza Virus Split Vaccine Capacity Production (10K
Pieces) and Growth Rate105
Table Sanofi-pasteur Company Information Table(Products Development History Location
Background Contact Information etc 14 Items) 105
Figure Sanofi-pasteur China Pharmaceutical Factories Distribution 107
Figure Influenza Virus Split Vaccine-Fanrling     107
Table 2009-2016 Sanofi-pasteur Influenza Virus Split Vaccine Capacity Production (100Million
Pieces) China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB)
Gross Margin List 108
Figure 2009-2016 Sanofi-pasteur Influenza Virus Split Vaccine Capacity Production (100Million
Pieces) and Growth Rate109
Table GSK Company Information Table(Products Development History Location Background
Contact Information etc 14 Items) 110
Figure GSK Shenzhen Influenza Vaccine Workshop Pictures          113
Figure GSK Influenza Split Vaccine - Fululishi 114
Table 2009-2016 GSKInfluenza Virus Split Vaccine Capacity Production (100Million Pieces)
China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross
Margin List 114
Figure 2009-2016 GSKInfluenza Virus Split Vaccine Capacity Production (100Million Pieces) and
Growth Rate 115
Table Novartis Company Information Table(Products Development History Location Background
Contact Information etc 14 Items) 116
Figure Novartis Subunit Influenza Vaccine - Agrippal 119
Figure Novartis Aged Population Special Use Influenza Vaccine - Fluad 120
Table 2009-2016 Novartis Influenza Virus Subunit Vaccine Capacity Production (100Million
Pieces) China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB)
Gross Margin List 121

QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717                7(8 Total)
2012 Deep Research Report on China Influenza Vaccine Industry

Figure 2009-2016 Novartis Influenza Virus Subunit Vaccine Capacity Production (100Million
Pieces) and Growth Rate121
Table Abbott Company Information Table(Products Development History Location Background
Contact Information etc 14 Items) 122
Figure Abbott Influenza Subunit Vaccine - Influvac 124
Table 2009-2016 Abbott Subunit Influenza Vaccine Capacity Production (100Million Pieces)
China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross
Margin List 124
Figure 2009-2016 Abbott Subunit Influenza Vaccine Capacity Production (100Million Pieces) and
Growth Rate 125
Table Crucell Company Information Table(Products Development History Location Background
Contact Information etc 14 Items) 126
Table Crucell Selling Vaccines and R&D Projects List 128
Table Crucell V Type Virion Adjuvant Influenza Vaccine (Subunit ) - Inflexal 129
Table 2009-2016 Crucell Subunit Influenza Vaccine Capacity Production (100Million Pieces)
China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross
Margin List 129
Table 2009-2016 Crucell Subunit Influenza Vaccine Capacity Production (100Million Pieces) and
Growth Rate 130
Table Tasly&Jenner Company Information Table(Products Development History Location
Background Contact Information etc 14 Items) 130
Figure Tasly&Jenner Factory Pictures 132
Figure Tasly&Jenner Subunit Influenza Virus Split Vaccine-Fuluoke®        132
Table 2009-2016 Tasly&Jenner Influenza Virus Subunit Vaccine Capacity Production (10K
Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 133
Table 2009-2016 Tasly&Jenner Influenza Virus Subunit Vaccine Capacity Production (10K
Pieces) and Growth Rate134
Table Neptunus Interlong Company Information Table(Products Development History Location
Background Contact Information etc 14 Items) 134
Figure Neptunus Interlong Vaccine Factory Picture    136
Figure Neptunus Interlong Vaccine Workshop Picture 136
Figure Neptunus Interlong Influenza Subunit Vaccine Package 137
Table 2009-2016 Neptunus Interlong Influenza Virus Subunit Vaccine Capacity Production (10K
Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 138
Table 2009-2016 Neptunus Interlong Influenza Virus Subunit Vaccine Capacity Production (10K
Pieces) and Growth Rate138
Table China 8Million Pieces/Year Influenza Vaccine Project Investments List 140
Table China 8Million Pieces/Year Influenza Vaccine Project Investment Feasibility Analysis 142




QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717              8(8 Total)

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2012 deep research report on china influenza vaccine industry

  • 1. 2012 Deep Research Report on China Influenza Vaccine Industry 2012 Deep Research Report on China Influenza Vaccine Industry Hard copy: 2200 USD Electronic copy (PDF):2200USD Global License: 4000USD Pages: 144 Tables and Figures: 155 Published Date: May 9 2012 Publisher: QY Research Group Contact: Mr. Zhang Dong 86-10-82945717 86-13811796901 sales@qyresearch.com Summary <2012 Deep Research Report on China Influenza Vaccine Industry > was a professional and depth research report on China Influenza Vaccine Industry. Firstly the report describes the background knowledge of Influenza Vaccine, including Concepts Classification Manufacturing process technical parameters and equipments List etc; then statistics International and China 16 Manufacturers Influenza Vaccine product 2009-2016 Capacity production cost price production value profit margins and other relevant data, statistics these enterprises Influenza Vaccine products, Product Specifications, company background information, then summary statistics and analysis the relevant data on these enterprises. The report got Global and China Influenza Vaccine companies production market share, China Influenza Vaccine demand supply and shortage, China Influenza Vaccine 2009-2016 production price cost profit production value profit margins, production market share by different Sources(China Domestic and Imported etc) . At the same time, the report analyzed and discussed supply and demand changes in Influenza Vaccine market and business development strategies, conduct a comprehensive analysis on China Influenza Vaccine industry trends. Finally, the report also introduced 8Million Pieces/year Influenza Vaccine project Feasibility analysis and related research conclusions. In a word, It was a depth research report on China Influenza Vaccine industry. And thanks to the support and assistance from Influenza Vaccine industry chain related experts and enterprises during QYResearch Vaccine Research Team survey and interview. QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717 1(8 Total)
  • 2. 2012 Deep Research Report on China Influenza Vaccine Industry Table of Contents Chapter One Influenza Vaccine Industry Overview 1 1.1 Definition 1 1.2 Classification 2 1.2.1 Seasonal Influenza Vaccine 2 1.2.2 Type A H1N1 Influenza Vaccine 4 1.2.3 Two Type Influenza Vaccine Comparison 6 1.3 Vaccine Inoculation 7 1.4 Industry Chain Structure 9 1.5Influenza Vaccine Development Prospect 15 1.5.1 United States Overplus 15 1.5.2 Seek Competitive Differentiation New Technology Prevalence 17 1.5.3 Huge Market Demand in China 18 Chapter Two Influenza Vaccine Manufacturing Technology and Process 19 2.1 Influenza Vaccine Manufacturing Technology Overview19 2.1.1 Embryo Culture Type A H1N1 Influenza Vaccine Manufacturing Process 20 2.1.2 Vero Cell Culture Inactivated Influenza Vaccine Manufacturing Process 23 2.2 Comparison of Two Procee Method 26 2.2.1 Embryo Culture Inactivated Influenza Vaccine Process Flow 26 2.2.2 Cell Culture Inactivated Influenza Vaccine Process Flow 27 2.2.3 Two Manufacturing Process Comparison 28 2.3 Influenza Vaccine Manufacturing Equipments List 30 2.4 Influenza Vaccine Manufacturing Process Today and Tomorrow 33 2.4.1 Influenza Vaccine Manufacturing Process Status 33 2.4.2 H1N1 Influenza Vaccine Manufacturing Process Problems 33 2.4.3 Influenza Vaccine New Manufacturing Technology 34 Chapter Three Influenza Vaccine Production Supply Sales Demand Market Status and Forecast 38 3.1 Influenza Vaccine Productions Overview 38 3.2 Influenza Vaccine Demand Overview 49 3.4 Influenza Vaccine Cost Price Production Value Gross Margin53 Chapter Four Influenza Vaccine Key Manufacturers 57 4.1 Hualan Bio (Henan) 57 4.2 Sinovac (Beijing) 65 4.3 Tianyuan Bio-pharma (Zhejiang) 73 4.4 Changsheng (Jilin Changchun) 77 4.5 Aleph Biomedical (Liaoning) 81 4.6 SIOBP (Shanghai) 87 4.7 CCBIO (Jilin Changchun) 91 QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717 2(8 Total)
  • 3. 2012 Deep Research Report on China Influenza Vaccine Industry 4.8 Lanzhou Institute of Biological Products (Qinghai)95 4.9 Tiantan Biological (Beijing) 99 4.10 Sanofi-pasteur (France) 105 4.11 GSK (UK) 109 4.12 Novartis (Switzerland) 116 4.13 Abbott (US) 122 4.14 Crucell (Holland) 125 4.15 Tasly&Jenner (Tianjin) 130 4.16 Neptunus Interlong (Shenzhen) 134 Chapter Five China 8Million Pieces/Year Influenza Vaccine Project Investment Feasibility Analysis 139 5.1 China 8Million Pieces/Year Influenza Vaccine Project Opportunities and Risks Analysis 139 5.1.1 Opportunities 139 5.1.2 Risks 140 5.3 China 8Million Pieces/Year Influenza Vaccine Project Investment Feasibility Analysis140 5.3.1 Project Overview 141 5.3.2 Capacity 141 5.3.3 Construction Standards 141 5.3.3 Construction Period 141 5.3.4 Project Schedule 141 5.3.5 Investment Feasibility Analysis 142 Chapter Six Influenza Vaccine Industry Research Conclusions 143 Tables and Figures Table Common Vaccines Classification 2 Table Three Type Influenza Vaccine (Inactivated Whole Virus Vaccine Split Vaccine Subunit Vaccine) Characteristic Comparison 4 Table United States Approval Type A influenza H1N1 Vaccine Suppliers and Product Specifications List 5 Table Europe Approval Type A influenza H1N1 Vaccine Suppliers and Product Specifications List 6 Figure China First Type Vaccine and Second Type Vaccine Classification and Application 10 Table First Type Vaccine and Second Type Vaccine Detail Market Analysis10 Table 2009-2010 China First Type Vaccine and Second Type Vaccine Issue Number (10K Pieces) and Market Share 11 Figure 2010 State-owned Private Foreign Enterprise Market Share in First Type Vaccine and Second Type Vaccine 11 Figure Influenza Vaccine Industry Chain Structure 12 Figure Vaccine Cold Chain Circulation System 13 Figure Vaccine Transportation Model 13 QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717 3(8 Total)
  • 4. 2012 Deep Research Report on China Influenza Vaccine Industry Figure First Type Vaccine Transportation Channel14 Figure Second Type Vaccine Transportation Channel 14 Figure Vaccine Transportation Steps and Process 15 Figure 2009-2019 Global Influenza Vaccine Market Scale(100 Million USD) 16 Figure 2007-2008 United States TOP5 Suppliers Influenza Vaccine Market Share 17 Figure China Influenza Vaccine Inoculation Coverage Rate and Its Gap to International Goal 18 Table Baxter Vero Cell Platform Background Information 23 Figure Embryo Culture Inactivated Vaccine Manufacturing Process Flow 26 Figure Cell Culture Inactivated Influenza Vaccine Manufacturing Process Flow 27 Figure Two Influenza Vaccine Manufacturing Process Comparison 28 Figure Influenza Vaccine Manufacturing Steps 30 Figure Influenza Vaccine Detection Steps 31 Table Influenza Vaccine Manufacturing Equipments List (38 Equipments) 32 Figure Influenza Vaccine Production Periodic Table 33 Figure Influenza Vaccine Production schedules 34 Table Influenza Vaccine Development History 35 Table Existing and R&D Influenza Vaccine Products List 35 Figure Influenza Vaccine New Manufacturing Technology 37 Table China 11 Manufacturers Influenza Vaccine Market Status List 38 Table Selling Influenza Vaccine in China 5 Foreign Suppliers List 39 Table 2009-2016 China 11 Manufacturers Influenza Vaccine Capacity and Total Capacity (10K Pieces) List 40 Table 2009-2016 China 11 Manufacturers Influenza Vaccine Capacity Market Share List 40 Table 2009-2016 China 11 Manufacturers Influenza Vaccine Production and Total Production (10K Pieces) List 41 Table 2009-2016 China 11 Manufacturers Influenza Vaccine Production Market Share List 42 Table 2009-2016 China Influenza Vaccine Capacity Production (10K Pieces) and Capacity Utilization Rate 42 Figure 2009-2016 China Influenza Vaccine Capacity Production (10K Pieces) and Growth Rate 43 Figure 2011 China Key Manufacturers Influenza Vaccine Production Market Share (China Government Approcal Data) 43 Table 2009-2016 Global Key Suppliers Influenza Vaccine Capacity and Total Capacity (100 Million Pieces) List43 Table 2009-2016 Global Key Suppliers Influenza Vaccine Production and Total Production (100 Million Pieces) List44 Figure 2009-2016 Global Influenza Vaccine Capacity Production (100 Million Pieces) and Growth Rate 44 Table 2009-2016 Global Influenza Vaccine Capacity Production (100 Million Pieces) and Capacity Utilization Rate 45 Figure 2011 Global Key Suppliers Influenza Vaccine Production Market Share 45 Table 2009-2016 Global Key Suppliers Influenza Vaccine China Sales (10K Pieces) List 45 Figure 2011 China Imported Influenza Vaccine Market Share By Suppliers (China Government Approval Data) 46 QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717 4(8 Total)
  • 5. 2012 Deep Research Report on China Influenza Vaccine Industry Table Global and China Key Suppliers Key Vaccine Products Sales in China 46 Table 2007-2011 China Influenza Vaccine Approval Amount by Suppliers (10K Pieces) 47 Figure 2011 China Influenza Vaccine Market Share by Splitting Vaccine and Subunit Vaccine (according China government approval amount) 48 Table 2009-2016 China local Influenza Vaccine and Imported Influenza Vaccine Market Share Comparison 48 Table 2001-2020 China Birth Rate and Population (10K) 49 Figure China India Korea Japan etc 9 Countries Child Mortality (‰) 49 Figure 1950-2050 China Working-age Population Proportion (%) 50 Table 2000-2050 China Age Over 60 Population (100 Million) and Proportion (%) 50 Figure 2010-2050 China Age Over 60 Over 65 Over 80 Population Proportion 51 Table 2001-2015 China Per Capita GDP (USD) and Growth Rate 51 Figure 2009-2016 China Influenza Vaccine Supply Demand (10K Pieces) and Growth Rate 52 Figure China Japan France etc 9 Countries Age Over 65 Population Influenza Vaccine Inoculation Coverage Rate52 Table 2009-2016 China Influenza Vaccine Supply Demand and Shortage (10K Pieces) 53 Table 2011 Hangzhou Disease Control and Prevention Center 33 Type Influenza Vaccine Products Purchase and Selling Price (RMB/Piece) 53 Table 2011 China and Imported Influenza Vaccine Capacity Production (10K Pieces) Price Cost Profit (RMB/Piece) Gross Margin List 56 Table 2009-2016 China Influenza Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 56 Table Hualan Bio Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 57 Figure Hualan Bio Vaccine Factory Picture 58 Figure Hualan Bio Influenza Virus Split Vaccine (Childhood Type) 59 Figure Hualan Bio Influenza Virus Split Vaccine (Adult Type) 61 Figure Hualan Bio Type A H1N1 Influenza Virus Split Vaccine 62 Table 2009-2016 Hualan Bio Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 64 Figure 2009-2016 Hualan Bio Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate 64 Table Sinovac Biotech Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 65 Table Sinovac Biotech Vaccine Plant Picture 66 Table Sinovac Biotech Development History Time Table 66 Figure Sinovac Biotech Influenza Virus Split Vaccine-Anrlaifu 67 Figure Sinovac Biotech Pandemic Influenza Virus Inactivated Vaccine - Panrlaifu 69 Figure Sinovac Biotech Type A H1N1 Influenza Virus Split Vaccine - Panrlaifu.1 71 Table 2009-2016 Sinovac Biotech Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 72 Figure 2009-2016 Sinovac Biotech Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate73 Table Tianyuan Bio-pharma Company Information Table(Products Development History Location QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717 5(8 Total)
  • 6. 2012 Deep Research Report on China Influenza Vaccine Industry Background Contact Information etc 14 Items) 73 Figure Tianyuan Bio-pharma Influenza Vaccine Products List 75 Figure Tianyuan Bio-pharma Influenza Virus Split Vaccine - Yuganning 75 Table 2009-2016 Tianyuan Bio-pharma Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 76 Figure 2009-2016 Tianyuan Bio-pharma Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate77 Table Changsheng Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 77 Figure Changsheng Influenza Virus Split Vaccine - Wanxin 79 Figure Changsheng Type A H1N1 Influenza Virus Split Vaccine 80 Table 2009-2016 Changsheng Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 80 Figure 2009-2016 Changsheng Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate 81 Table Aleph Biomedical Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 81 Table Aleph Biomedical Contact Information List82 Figure Aleph Biomedical Influenza Vaccine Manufacturing Workshop 83 Figure Aleph Biomedical Influenza Virus Split Vaccine(Adult Type) 84 Figure Aleph Biomedical Influenza Virus Split Vaccine (Childhood Type) 85 Table 2009-2016 Aleph Biomedical Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 86 Figure 2009-2016 Aleph Biomedical Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate86 Table SIOBP (Shanghai Institute of Biological Products) Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 87 Figure CNBG and Six Institutes Equity Relationship 88 Figure SIOBP Influenza Virus Split Vaccine 89 Figure SIOBP Type A H1N1 Influenza Virus Split Vaccine 89 Table 2009-2016 SIOBP Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 90 Figure 2009-2016 SIOBP Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate 91 Table CCBIO(Changchun Institute of Biological Products) Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 91 Figure CCBIO Influenza Split Vaccine - Shipulir 93 Figure CCBIO Factory Workshop Picture 93 Table 2009-2016 CCBIO Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 94 Figure 2009-2016 CCBIO Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate 95 Table Lanzhou Institute of Biological Products Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 95 QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717 6(8 Total)
  • 7. 2012 Deep Research Report on China Influenza Vaccine Industry Figure Lanzhou Institute of Biological Products Factory Picture 97 Figure Lanzhou Institute of Biological Products Trivalent Influenza Split Vaccine 97 Table 2009-2016 Lanzhou Institute of Biological Products Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 97 Figure 2009-2016 Lanzhou Institute of Biological Products Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate 98 Table Tiantan Biological Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 99 Figure Tiantan Biological Control Shares of Sinopharm 101 Figure Tiantan Biological and Related Control Subsidiaries Relationship 101 Figure Tiantan Biological Factory Picture 102 Figure Tiantan Biological Beijing Yizhuang Vaccine Plants Picture 102 Figure Tiantan Biological Type A H1N1 Influenza Virus Split Vaccine 103 Figure Tiantan Biological Influenza Virus Split Vaccine 103 Table 2009-2016 Tiantan Biological Influenza Virus Split Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 104 Figure 2009-2016 Tiantan Biological Influenza Virus Split Vaccine Capacity Production (10K Pieces) and Growth Rate105 Table Sanofi-pasteur Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 105 Figure Sanofi-pasteur China Pharmaceutical Factories Distribution 107 Figure Influenza Virus Split Vaccine-Fanrling 107 Table 2009-2016 Sanofi-pasteur Influenza Virus Split Vaccine Capacity Production (100Million Pieces) China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 108 Figure 2009-2016 Sanofi-pasteur Influenza Virus Split Vaccine Capacity Production (100Million Pieces) and Growth Rate109 Table GSK Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 110 Figure GSK Shenzhen Influenza Vaccine Workshop Pictures 113 Figure GSK Influenza Split Vaccine - Fululishi 114 Table 2009-2016 GSKInfluenza Virus Split Vaccine Capacity Production (100Million Pieces) China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 114 Figure 2009-2016 GSKInfluenza Virus Split Vaccine Capacity Production (100Million Pieces) and Growth Rate 115 Table Novartis Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 116 Figure Novartis Subunit Influenza Vaccine - Agrippal 119 Figure Novartis Aged Population Special Use Influenza Vaccine - Fluad 120 Table 2009-2016 Novartis Influenza Virus Subunit Vaccine Capacity Production (100Million Pieces) China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 121 QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717 7(8 Total)
  • 8. 2012 Deep Research Report on China Influenza Vaccine Industry Figure 2009-2016 Novartis Influenza Virus Subunit Vaccine Capacity Production (100Million Pieces) and Growth Rate121 Table Abbott Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 122 Figure Abbott Influenza Subunit Vaccine - Influvac 124 Table 2009-2016 Abbott Subunit Influenza Vaccine Capacity Production (100Million Pieces) China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 124 Figure 2009-2016 Abbott Subunit Influenza Vaccine Capacity Production (100Million Pieces) and Growth Rate 125 Table Crucell Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 126 Table Crucell Selling Vaccines and R&D Projects List 128 Table Crucell V Type Virion Adjuvant Influenza Vaccine (Subunit ) - Inflexal 129 Table 2009-2016 Crucell Subunit Influenza Vaccine Capacity Production (100Million Pieces) China Sales (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 129 Table 2009-2016 Crucell Subunit Influenza Vaccine Capacity Production (100Million Pieces) and Growth Rate 130 Table Tasly&Jenner Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 130 Figure Tasly&Jenner Factory Pictures 132 Figure Tasly&Jenner Subunit Influenza Virus Split Vaccine-Fuluoke® 132 Table 2009-2016 Tasly&Jenner Influenza Virus Subunit Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 133 Table 2009-2016 Tasly&Jenner Influenza Virus Subunit Vaccine Capacity Production (10K Pieces) and Growth Rate134 Table Neptunus Interlong Company Information Table(Products Development History Location Background Contact Information etc 14 Items) 134 Figure Neptunus Interlong Vaccine Factory Picture 136 Figure Neptunus Interlong Vaccine Workshop Picture 136 Figure Neptunus Interlong Influenza Subunit Vaccine Package 137 Table 2009-2016 Neptunus Interlong Influenza Virus Subunit Vaccine Capacity Production (10K Pieces) Price Cost Gross (RMB/Piece) Production Value (10K RMB) Gross Margin List 138 Table 2009-2016 Neptunus Interlong Influenza Virus Subunit Vaccine Capacity Production (10K Pieces) and Growth Rate138 Table China 8Million Pieces/Year Influenza Vaccine Project Investments List 140 Table China 8Million Pieces/Year Influenza Vaccine Project Investment Feasibility Analysis 142 QYResearch Mr. Zhangdong sales@qyresearch.com 13811796901 8610-82945717 8(8 Total)