This document certifies that Miss Ganchen Dong received a Bachelor's Degree in Management from the Beijing Institute of Graphic Communication in June 2013, having completed a 4-year undergraduate program in the Management of Cultural Industry from September 2009 to June 2013, passing all required courses.
This document certifies that Miss Ganchen Dong received a Bachelor's Degree in Management from the Beijing Institute of Graphic Communication in June 2013, having completed a 4-year undergraduate program in the Management of Cultural Industry from September 2009 to June 2013, passing all required courses.
This doctoral dissertation discusses molecular dynamics simulations of polyglutamine and insulin aggregation. Two projects are described. The first uses replica-exchange molecular dynamics to simulate one and two polyglutamine peptides. It finds the peptides form helical or coil structures at long distances but β-sheets at short distances. The second simulates insulin and binding peptides LVEALYL and RGFFYT. It discovers both peptides aggregate into β-sheets and bind strongly to insulin.
This doctoral dissertation discusses molecular dynamics simulations of polyglutamine and insulin aggregation. Two projects are described. The first uses replica-exchange molecular dynamics to simulate one and two polyglutamine peptides. It finds the peptides form helical or coil structures at long distances but β-sheets at short distances. The second simulates insulin and binding peptides LVEALYL and RGFFYT. It discovers both peptides aggregate into β-sheets and bind strongly to insulin.
