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PradeepMK
M.Sc. Nursing I year
Seminar
Presentation
CONTENTS
Introduction
A Definition
B
Causes
C Pathophysiology
D
Signs & Symptoms
E Diagnostic Evaluation
F
G Management
Introduction;
A
Hemorrhagic shock occurs when the body begins to
shut down due to heavy blood loss. People
suffering injuries that cause heavy bleeding may go
into hemorrhagic shock if the bleeding isn't stopped
immediately.
Definition;
B
Hemorrhagic shock is a condition of reduced
tissue perfusion, resulting in the inadequate
delivery of oxygen and nutrients that are
necessary for cellular function. Whenever
cellular oxygen demand out weighs supply,
both the cell and the organism are in a state
of shock.
Cont....
On a multi-cellular level, the definition of shock becomes
more difficult because not all tissues and organs will
experience the same amount of oxygen imbalance for a
given clinical disturbance. Clinicians struggle daily to
adequately define and monitor oxygen utilization on the
cellular level and to correlate this physiology to useful
clinical parameters and diagnostic tests.
Hypovolemic
Septic
Cardiogenic (Obstructive)
Neurogenic
Four Classes of Shock;
Causes of Hemorrhagic Shock;
Deep Cuts
1
Gunshot Wounds
2
Trauma
3
Blunt Injury
4 5 6
Severe Burns
Amputations
C
Cont;
Cont;
 Hemorrhagic shock is caused by the loss of both
circulating blood volume and oxygen-carrying
capacity. The most common clinical etiologies are
penetrating and blunt trauma, gastrointestinal
bleeding, and obstetrical bleeding.
Pathophysiology,
D
Cont;
 At the site of hemorrhage, clotting cascade and
platelets form a hemostatic plug whereas remote
from the site fibrinolytic activity increases,
presumably to prevent microvascular thrombosis.
 However excess plasmin activity and
autoheparinization can lead to pathologic
hyperfibrinolysis and coagulopathy.
Cont;
 There is transition to anaerobic metabolism
which generates lactic acid, inorganic
phosphates and oxygen radicals.
 Release of Damage Associated Molecular
Patterns (DAMP) incites a systemic
inflammatory response.
 As ATP levels deplete, cellular homeostasis
fails and cell death ensues
Cont; External Hemorrhage
• Results from soft tissue injury.
• Most soft tissue trauma is accompanied by mild
hemorrhage and is not life threatening.
–Can carry significant risks of patient morbidity and
disfigurement
• The seriousness of the injury is dependent on:
– Anatomical source of the hemorrhage (arterial,
venous, capillary)
– Degree of vascular disruption
– Amount of blood loss that can be tolerated by the patient
Cont; Internal Hemorrhage
• Can result from:
–Blunt or penetrating trauma
–Acute or chronic medical illnesses
• Internal bleeding that can cause hemodynamic instability
usually occurs in one of four body cavities:
–Chest
–Abdomen
–Pelvis
–Retroperitoneum
Compensated Shock;
• 0-20% of blood loss
• Blood pressure is
maintained via
increased vascular
tone and increased
blood flow to vital
organs
Cont....
Signs & Symptoms;
Blue lips &
fingernails
1
Low (or) no urine
output
2
Profuse
sweating
3
Dizziness
4 5 6
Anxiety
Shallow Breathing
E
Cont....
Chest pain
7
Loss of
consciousness
8
Low blood
pressure
9
Weak pulse
10 11 12
Confusion
Rapid heart rate
Cont....
Blood in the
stool
13
Blood in the urine
14
Vaginal bleeding
15
Chest pain
16 17 18
Abdominal
pain/swelling
Blood vomiting
Cont...,
• The organs who win -
Brain
Heart
Kidney
Liver
• The organs who lose –
Skin
GI tract
Muscles
Diagnostic Evaluation;
Physical
Examination
Chest
radiographs
CT Scan
Imaging
studies
Abdominal
radiographs
F
Cont....
Esophago
Gastro
duodenoscopy
Ultrasounds
Nuclear
medicine
scanning
Colonoscopy Angiography
Cont...,
• Initial Assessment
–General Impression
–Obvious bleeding
–Mental Status
–Interventions
• Manage as you go
–O2
–Bleeding control
–Shock
–BLS before ALS!
Cont...,
• Focused History & Physical examination
– Rapid Trauma Assessment
• Full head to toe
• Consider air medical if stage 2+ blood loss
– Focused Physical Exam
• Guided by c/c
– Vitals, SAMPLE,
– Additional Assessment
• Orthostatic hypotension
• Tilt test: 20
– ↓BP or ↑P from supine tositting
Cont...,
• Fractures and Blood Loss
• Pelvic fracture →
• Femur fracture
• Tibia/fibula fracture →
• Hematomas and
contusions →
2,000 mL
1,500 mL
500–750 mL
500 mL
Cont...,
• Ongoing Assessment;
– Reassess vitals and mental status:
• Q 5 min: UNSTABLE patients
• Q 15 min: STABLE patients
– Reassess interventions:
• Oxygen
• ET
• IV
• Medication actions
– Trending: improvement vs. deterioration
• Pulse oximetry
• End-tidal CO2 levels
Management of Shock;
Management of ABC Fluid replacement
Vasoactive medications
G
Shock required immediate intervention to preserve life. Re-
establishing perfusion to the organs is the primary goal through restoring
and maintaining the blod circulating volume ensuring oxygenation and
blood pressure are adequate, achieving and maintaining effective cardiac
function and preventing complications.
Nutritional support
1. Management of ABC;
A - Airway
B - Breathing
C - Circulation
 Secure the airway, breathing and
circulation, by performing cardio
pulmonary resuscitation (or) life support
measurements
 Provide oxygen supplements through nasal
cannula, mask (or) endotrachial intubation
(or) mechanical ventilator.
2.Fluid replacement to restore intravascular;
 Stop further bleeding- Recent studies indicates that
tourniquet application proximal to the site of
hemorrhage in the extremities saves lives without
risking amputation or extremity dysfunction, if the
patient can be quickly transported to the hospital.
 Isotonic crystalloid resuscitation has been used for
decades in early management of bleeding. However
they only transiently expand the intravascular
volume & have no intrinsic therapeutic benefit.
 Overzealous resuscitation with crystalloid dilutes the
oxygen carrying capacity and clotting factors.
 Limiting crystalloid infusion to 3L in 1st 6 hours is
recommended as a part of bundle of care for
patients with acute bleeding & trauma.
Cont....
 Blood Transfusion;
• Blood products transfusion provide a greater survival benefit
as compared to colloids/crystalloids
TYPES-
• Red blood cells
• Plasma
• Platelets
• Cryoprecipitate
• Prospective studies show that 1:1:1 ratio of plasma to
platelets to RBC’s is safe
• However all these contain citrate which can lead to
hypocalcemia &
progressive coagulopathy.
• Thus empirical dosing of calcium & frequent measurement of
electrolytes is recommended.
Cont....
 Vasopressor therapy initially to target a mean
arterial pressure (MAP) of 65 mm Hg
Norepinephrine as the first choice vasopressor
 Epinephrine (added to and potentially
substituted for norepinephrine) when an
additional agent is needed to maintain
adequate blood pressure
 Vasopressin 0.03 units/minute can be added to
norepinephrine (NE) with intent of either raising
MAP or decreasing NE dosage
Cont- Emergency care & First aid;
 Rapid evaluation
 Damage control resuscitation
 CXR, Pelvis X-Ray,ICD Insertion
 Permissive hypotension
 Control hemorrhage
 Prevent contamination
 Avoid further injuries
 Initial homeostasis and packing.
Cont- Emergency care & First aid;
 Reverse the sequel of hypotension
 Physiological and biochemical restoration
 Adequate Oxygen delivery
 Agressive core rewarming
 Correction of coagulopathy
 Definitive surgery
Decrease cardiac output related to
• Alteration in heart rate & rhythm
• Decreased ventricular filling
• Fluid volume loss of 30% (or) more
• Late uncompensated shock
Difficult fluid volume, decreased intravascular,
interstitial and intracellular fluid may related to
• Active fluid volume loss
• Internal fluid shifts
• Regulatory mechanism failure
NURSING MANAGEMENT;
Nursing diagnosis;
Complications;
Multiple organ
failure
01
Kidney damage
02
Gangrene
develops
03
Death
04
Summary
THANK YOU

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Hemorrhagic Shock Management

  • 3. CONTENTS Introduction A Definition B Causes C Pathophysiology D Signs & Symptoms E Diagnostic Evaluation F G Management
  • 4. Introduction; A Hemorrhagic shock occurs when the body begins to shut down due to heavy blood loss. People suffering injuries that cause heavy bleeding may go into hemorrhagic shock if the bleeding isn't stopped immediately.
  • 5. Definition; B Hemorrhagic shock is a condition of reduced tissue perfusion, resulting in the inadequate delivery of oxygen and nutrients that are necessary for cellular function. Whenever cellular oxygen demand out weighs supply, both the cell and the organism are in a state of shock.
  • 6. Cont.... On a multi-cellular level, the definition of shock becomes more difficult because not all tissues and organs will experience the same amount of oxygen imbalance for a given clinical disturbance. Clinicians struggle daily to adequately define and monitor oxygen utilization on the cellular level and to correlate this physiology to useful clinical parameters and diagnostic tests.
  • 8. Causes of Hemorrhagic Shock; Deep Cuts 1 Gunshot Wounds 2 Trauma 3 Blunt Injury 4 5 6 Severe Burns Amputations C
  • 10. Cont;  Hemorrhagic shock is caused by the loss of both circulating blood volume and oxygen-carrying capacity. The most common clinical etiologies are penetrating and blunt trauma, gastrointestinal bleeding, and obstetrical bleeding.
  • 12. Cont;  At the site of hemorrhage, clotting cascade and platelets form a hemostatic plug whereas remote from the site fibrinolytic activity increases, presumably to prevent microvascular thrombosis.  However excess plasmin activity and autoheparinization can lead to pathologic hyperfibrinolysis and coagulopathy.
  • 13. Cont;  There is transition to anaerobic metabolism which generates lactic acid, inorganic phosphates and oxygen radicals.  Release of Damage Associated Molecular Patterns (DAMP) incites a systemic inflammatory response.  As ATP levels deplete, cellular homeostasis fails and cell death ensues
  • 14. Cont; External Hemorrhage • Results from soft tissue injury. • Most soft tissue trauma is accompanied by mild hemorrhage and is not life threatening. –Can carry significant risks of patient morbidity and disfigurement • The seriousness of the injury is dependent on: – Anatomical source of the hemorrhage (arterial, venous, capillary) – Degree of vascular disruption – Amount of blood loss that can be tolerated by the patient
  • 15. Cont; Internal Hemorrhage • Can result from: –Blunt or penetrating trauma –Acute or chronic medical illnesses • Internal bleeding that can cause hemodynamic instability usually occurs in one of four body cavities: –Chest –Abdomen –Pelvis –Retroperitoneum
  • 16. Compensated Shock; • 0-20% of blood loss • Blood pressure is maintained via increased vascular tone and increased blood flow to vital organs
  • 18. Signs & Symptoms; Blue lips & fingernails 1 Low (or) no urine output 2 Profuse sweating 3 Dizziness 4 5 6 Anxiety Shallow Breathing E
  • 19. Cont.... Chest pain 7 Loss of consciousness 8 Low blood pressure 9 Weak pulse 10 11 12 Confusion Rapid heart rate
  • 20. Cont.... Blood in the stool 13 Blood in the urine 14 Vaginal bleeding 15 Chest pain 16 17 18 Abdominal pain/swelling Blood vomiting
  • 21. Cont..., • The organs who win - Brain Heart Kidney Liver • The organs who lose – Skin GI tract Muscles
  • 24. Cont..., • Initial Assessment –General Impression –Obvious bleeding –Mental Status –Interventions • Manage as you go –O2 –Bleeding control –Shock –BLS before ALS!
  • 25. Cont..., • Focused History & Physical examination – Rapid Trauma Assessment • Full head to toe • Consider air medical if stage 2+ blood loss – Focused Physical Exam • Guided by c/c – Vitals, SAMPLE, – Additional Assessment • Orthostatic hypotension • Tilt test: 20 – ↓BP or ↑P from supine tositting
  • 26. Cont..., • Fractures and Blood Loss • Pelvic fracture → • Femur fracture • Tibia/fibula fracture → • Hematomas and contusions → 2,000 mL 1,500 mL 500–750 mL 500 mL
  • 27. Cont..., • Ongoing Assessment; – Reassess vitals and mental status: • Q 5 min: UNSTABLE patients • Q 15 min: STABLE patients – Reassess interventions: • Oxygen • ET • IV • Medication actions – Trending: improvement vs. deterioration • Pulse oximetry • End-tidal CO2 levels
  • 28. Management of Shock; Management of ABC Fluid replacement Vasoactive medications G Shock required immediate intervention to preserve life. Re- establishing perfusion to the organs is the primary goal through restoring and maintaining the blod circulating volume ensuring oxygenation and blood pressure are adequate, achieving and maintaining effective cardiac function and preventing complications. Nutritional support
  • 29. 1. Management of ABC; A - Airway B - Breathing C - Circulation  Secure the airway, breathing and circulation, by performing cardio pulmonary resuscitation (or) life support measurements  Provide oxygen supplements through nasal cannula, mask (or) endotrachial intubation (or) mechanical ventilator.
  • 30. 2.Fluid replacement to restore intravascular;  Stop further bleeding- Recent studies indicates that tourniquet application proximal to the site of hemorrhage in the extremities saves lives without risking amputation or extremity dysfunction, if the patient can be quickly transported to the hospital.  Isotonic crystalloid resuscitation has been used for decades in early management of bleeding. However they only transiently expand the intravascular volume & have no intrinsic therapeutic benefit.  Overzealous resuscitation with crystalloid dilutes the oxygen carrying capacity and clotting factors.  Limiting crystalloid infusion to 3L in 1st 6 hours is recommended as a part of bundle of care for patients with acute bleeding & trauma.
  • 31. Cont....  Blood Transfusion; • Blood products transfusion provide a greater survival benefit as compared to colloids/crystalloids TYPES- • Red blood cells • Plasma • Platelets • Cryoprecipitate • Prospective studies show that 1:1:1 ratio of plasma to platelets to RBC’s is safe • However all these contain citrate which can lead to hypocalcemia & progressive coagulopathy. • Thus empirical dosing of calcium & frequent measurement of electrolytes is recommended.
  • 32. Cont....  Vasopressor therapy initially to target a mean arterial pressure (MAP) of 65 mm Hg Norepinephrine as the first choice vasopressor  Epinephrine (added to and potentially substituted for norepinephrine) when an additional agent is needed to maintain adequate blood pressure  Vasopressin 0.03 units/minute can be added to norepinephrine (NE) with intent of either raising MAP or decreasing NE dosage
  • 33. Cont- Emergency care & First aid;  Rapid evaluation  Damage control resuscitation  CXR, Pelvis X-Ray,ICD Insertion  Permissive hypotension  Control hemorrhage  Prevent contamination  Avoid further injuries  Initial homeostasis and packing.
  • 34. Cont- Emergency care & First aid;  Reverse the sequel of hypotension  Physiological and biochemical restoration  Adequate Oxygen delivery  Agressive core rewarming  Correction of coagulopathy  Definitive surgery
  • 35. Decrease cardiac output related to • Alteration in heart rate & rhythm • Decreased ventricular filling • Fluid volume loss of 30% (or) more • Late uncompensated shock Difficult fluid volume, decreased intravascular, interstitial and intracellular fluid may related to • Active fluid volume loss • Internal fluid shifts • Regulatory mechanism failure NURSING MANAGEMENT; Nursing diagnosis;