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These are simplified slides discussing the regulation of cardiac output and venous return. Learning objectives: 1. Comprehend the determinants of cardiac output and factors affecting cardiac output 2. Comprehend the factors affecting stroke volume and heart rate and total peripheral resistance 3. Identify the factors regulating venous return 4. Discuss the causes of high and low output cardiac failure 5. Enlist the functions of veins and recognise the significance of venous reservoirs Study Resources: 1. Chapter 20, Guyton and Hall Textbook of Medical Physiology, 14th edition 2. Chapter 30 and 32, Ganong’s Review of Medical Physiology, 26th edition 3. Chapter 10, Human Physiology by Lauralee Sherwood, 9th edition 4. Physiology, Cardiac Output - StatPearls https://www.ncbi.nlm.nih.gov/books/NBK470455/
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In this comprehensive lecture, Dr. Faiza delves deep into the physiologic anatomy of the heart and the intricate properties of cardiac muscles. Beginning with a thorough exploration of the circulatory system, she meticulously elucidates the physiological arrangement of the right and left hearts, providing a detailed overview of systemic circulation's parallel arrangement. Through meticulous explanation, she traces the intricate path of blood flow, providing insightful comparisons of pressures across various components of the heart and circulatory tree, offering a holistic understanding of cardiovascular dynamics. Transitioning seamlessly, Dr. Faiza meticulously dissects the functional anatomy and mechanics of the atrioventricular and semilunar valves, essential components for maintaining the precise unidirectional flow of blood within the heart. By delving into their structure and function, she illuminates their pivotal role in cardiac physiology, elucidating their mechanisms to prevent backflow and ensure efficient circulation. Furthermore, Dr. Faiza embarks on a detailed exploration of the properties of cardiac muscles, providing a comprehensive understanding of their histological composition, syncytial arrangement, and action potential characteristics. Through detailed analysis, she sheds light on the factors influencing contractility, including sympathetic stimulation, hormonal regulation, and alterations in extracellular and intracellular ion concentrations. Throughout the lecture, Dr. Faiza employs illustrative diagrams and engaging explanations to facilitate understanding, ensuring students grasp the intricate nuances of cardiac physiology. By elucidating the fundamental concepts underlying heart anatomy and cardiac muscle properties, she equips learners with the foundational knowledge necessary for a comprehensive understanding of cardiovascular function and pathology.
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